Abstract：
:Robot-assisted laparoscopic radical prostatectomy (RALRP) is a minimally invasive procedure; however, some amount of surgical trauma that can trigger systemic inflammation remains. Moreover, pneumoperitoneum during RALRP induces ischemia-reperfusion injury (IRI). Propofol, an anesthetic, is known to have anti-inflammatory and antioxidant properties. In the present study, we compared the effects of propofol with those of desflurane on inflammation and IRI during RALRP via measurements of different biomarkers and evaluation of perioperative renal function. Fifty patients were randomized to receive either desflurane (n = 25) or propofol (n = 25) with remifentanil during RALRP. Serum levels of interleukin (IL)-6 (IL-6), tumor necrosis factor alpha, C-reactive protein, and nitric oxide were measured 10 min after anesthesia induction (T1), 100 min after carbon dioxide (CO2) insufflation (T2), and 10 min after CO2 deflation (T3). Perioperative urine outputs and the serum creatinine level at 24 h after surgery were also recorded. We found that IL-6 levels at T2 and T3 were higher than those at T1 in both groups, although the increases were significant attenuated only in the propofol group. The other parameters showed no differences among the three time points in both groups. The intraoperative urine output was significantly higher in the propofol group than in the desflurane group, while the creatinine level showed no significant changes in either group. Our findings suggest that propofol can not only attenuate the inflammatory response during and after pneumoperitoneum in patients undergoing RALRP but also prevent oliguria during pneumoperitoneum.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Roh GU,Song Y,Park J,Ki YM,Han DWdoi
10.1038/s41598-019-41708-xsubject
Has Abstractpub_date
2019-03-27 00:00:00pages
5242issue
1issn
2045-2322pii
10.1038/s41598-019-41708-xjournal_volume
9pub_type
杂志文章,随机对照试验abstract：:Direct growth of MoS2 nanowalls on vapor grown carbon nanofibers (VGCNFs) has been achieved using a microwave-assisted hydrothermal (MAH) method under an acidic condition. The acidic condition was obtained through the addition of an HCl aqueous solution. We demonstrate that the HCl not only modifies the pH value for l...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-05805-z
更新日期：2017-07-20 00:00:00
abstract：:In this study, an anatase/rutile mixed-phase titanium dioxide (TiO2) hierarchical network deposited with Au nanoparticles (Au/TiO2 ARHN) was synthesized using a facile hydrothermal method followed by a simple calcination step. Such a unique structure was designed for improving the light harvest, charge transportation/...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep42524
更新日期：2017-02-10 00:00:00
abstract：:Bioavailability of α-tocopherol varies with source, dose and duration of supplementation. The effect of source and dose of α-tocopherol on response of α-tocopherol stereoisomers in plasma and tissues of mink kits during the weaning period was studied. Twelve mink kits were euthanised in CO2 at the beginning of the exp...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-80902-0
更新日期：2021-01-29 00:00:00
abstract：:The concept of milk as a healthy food has opened the way for studies on milk components, from nutrients to microRNAs, molecules with broad regulatory properties present in large quantities in milk. Characterization of these components has been performed in several species, such as humans and bovine, depending on the s...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-56690-7
更新日期：2019-12-30 00:00:00
abstract：:The group-IV tin has been hypothesized to possess intriguing electronic properties in an atom-thick hexagonal form. An attractive pathway of producing sizable 2D crystallites of tin is based on deintercalation of bulk compounds with suitable tin frameworks. Here, we have identified a new synthesizable metal distannide...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep28369
更新日期：2016-07-08 00:00:00
abstract：:Congenital reproductive tract anomalies could impair fertility. Female and male reproductive tracts are developed from Müllerian ducts and Wolffian ducts, respectively, involving initiation, elongation and differentiation. Genetic basis solely for distal reproductive tract development is largely unknown. Lhfpl2 (lipom...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep23037
更新日期：2016-03-11 00:00:00
abstract：:Experiments were conducted to improve jenny conception rates through induced ovulation and timed insemination. Jennies in control, hCG and LH groups were injected intramuscularly with saline alone or saline containing hCG or LH, respectively, when the dominant follicle diameter reached 35 mm. Then, follicle developmen...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-39757-3
更新日期：2019-03-01 00:00:00
abstract：:Medical image segmentation is an important tool for current clinical applications. It is the backbone of numerous clinical diagnosis methods, oncological treatments and computer-integrated surgeries. A new class of machine learning algorithm, deep learning algorithms, outperforms the results of classical segmentation ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-69920-0
更新日期：2020-08-13 00:00:00
abstract：:In this paper, for the first time, the switchable two-color quantum dot laser has been realized considering solution process technology, which has both simultaneous and lonely lasing capability exploiting selective energy contacts. Furthermore, both channels can be modulated independently, which is a significant featu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-60859-w
更新日期：2020-03-24 00:00:00
abstract：:We have employed a model system, inspired by SNARE proteins, to facilitate membrane fusion between Giant Unilamellar Vesicles (GUVs) and Large Unilamellar Vesicles (LUVs) under physiological conditions. In this system, two synthetic lipopeptide constructs comprising the coiled-coil heterodimer-forming peptides K4, (KI...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-59926-z
更新日期：2020-02-20 00:00:00
abstract：:It is unclear whether N-acetylaspartate (NAA) depletions documented in schizophrenia patients might be due to the disease progression or medications. Here we investigated longitudinal NAA changes in drug-naïve first-episode patients (FEP) who are relatively free from chronicity. Forty-two drug-naïve FEP and 38 control...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep09109
更新日期：2015-03-16 00:00:00
abstract：:Many plant essential oils and their terpenoid constituents possess bioactivities including insecticidal activity, and they sometimes act synergistically when mixed. Although several hypotheses for this have been proposed, the underlying mechanism has not been fully elucidated thus far. In the present study, we report ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep42432
更新日期：2017-02-09 00:00:00
abstract：:Photonic qubits lie at the heart of quantum information technology, often encoding information in their polarization state. So far, only low-frequency optical and infrared photons have been employed as flying qubits, as the resources that are at present easiest to control. With their essentially different way of inter...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep25136
更新日期：2016-04-27 00:00:00
abstract：:Shoulder problems are common in patients with a cervical herniated intervertebral disc (HIVD). This study aimed to explore the incidence and risk of shoulder capsulitis/tendonitis following cervical HIVD surgery. We used data from the Taiwan "Longitudinal Health Insurance Database". We identified all patients who were...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep26898
更新日期：2016-05-27 00:00:00
abstract：:Our data about pathogenesis of hepatic steatosis after liver transplantation is scarce. This study aimed to investigate the association between serum adipokines and insulin resistance with hepatic steatosis in liver transplant recipients. We investigated the association between insulin resistance, serum adiponectin, i...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-69571-1
更新日期：2020-07-29 00:00:00
abstract：:This study aims to identify promising biomarkers for the early detection of lung cancer and evaluate the prognosis of lung cancer patients. Genome-wide mRNA expression data obtained from the Gene Expression Omnibus (GSE19188, GSE18842 and GSE40791), including 231 primary tumor samples and 210 normal samples, were used...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-08615-5
更新日期：2017-08-14 00:00:00
abstract：:Multiplexed or simultaneous detection of multiple analytes is a valuable tool in many analytical applications. However, complications caused by the presence of interfering compounds in a sample form a major drawback in existing molecular sensor technologies, particularly in multi-analyte systems. Although separating a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep06785
更新日期：2014-10-30 00:00:00
abstract：:Knowledge about a tool's dynamics can be acquired from the visual configuration of the tool and through physical interaction. Here, we examine how visual information affects the generalization of dynamic learning during tool use. Subjects rotated a virtual hammer-like object while we varied the object dynamics separat...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-39507-5
更新日期：2019-02-25 00:00:00
abstract：:Clinicians often hesitate prescribing corticosteroids to treat corticosteroid-responsive conditions in sickle cell disease (SCD) patients because their use can be associated with complications (increased hospital readmission, rebound pain, strokes, avascular necrosis, acute chest syndrome). Consequently, SCD patients ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-24274-6
更新日期：2018-04-17 00:00:00
abstract：:The adipokines chemerin and omentin-1 have been suggested to influence cardiovascular function. The study aimed to investigate the longitudinal association between chemerin, omentin-1 concentrations and risk of incident heart failure (HF), respectively. We conducted a case-cohort study nested within the European Prosp...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-14518-2
更新日期：2017-10-26 00:00:00
abstract：:Giant spin Hall effect (GSHE) has received significant attention for its potential in future spintronic applications. Spin current via GSHE-based thin films provides an effective and promising means to manipulate magnetization. However, an external in-plane magnetic field is required to consistently switch the perpend...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-26586-z
更新日期：2018-05-25 00:00:00
abstract：:In the current report, we describe the identification of three genetically distinct groups of prophages integrated into three different chromosomal sites of human gut-associated Bifidobacterium breve and Bifidobacterium longum strains. These bifidobacterial prophages are distantly related to temperate actinobacterioph...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-31181-3
更新日期：2018-08-24 00:00:00
abstract：:Ocean warming with climate change is forcing marine organisms to shift their distributions polewards and phenology. In warm tropical seas, evolutionary adaptation by local species to warming will be crucial to avoid predicted desertification and reduction in diversity. However, little is known about the adaptation of ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-36091-y
更新日期：2018-12-11 00:00:00
abstract：:Garcinia L. (Clusiaceae) fruits are a rich source of (-)-hydroxycitric acid, and this has gained considerable attention as an anti-obesity agent and a popular weight loss food supplement. In this study, we assessed adulteration of morphologically similar samples of Garcinia using DNA barcoding, and used NMR to quantif...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-28635-z
更新日期：2018-07-12 00:00:00
abstract：:It is well known that collective migrations of oxygen vacancies in oxide is the key principle of resistance change in oxide-based resistive memory (OxRAM). The practical usefulness of OxRAM mainly arises from the fact that these oxygen vacancy migrations take place at relatively low operating voltages. The activation ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-53498-3
更新日期：2019-11-19 00:00:00
abstract：:Ooids are typically spherical sediment grains characterised by concentric layers encapsulating a core. There is no universally accepted explanation for ooid genesis, though factors such as agitation, abiotic and/or microbial mineralisation and size limitation have been variously invoked. Here we examine the possible i...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-18908-4
更新日期：2018-01-11 00:00:00
abstract：:Cu removal by a novel multi-amines decorated resin (PAMD) from wastewater in the absence or presence of citric acid (CA) was examined. Adsorption capacity of Cu onto PAMD markedly increased by 186% to 5.07 mmol/g in the presence of CA, up to 7 times of that onto four commercial resins under the same conditions. Preloa...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep09944
更新日期：2015-05-12 00:00:00
abstract：:Plastic pollution is a rapidly worsening environmental problem, especially in oceanic habitats. Environmental pollution with microplastic particles is also causing food consumed by humans to be increasingly polluted, including table salts. Therefore, we present the first study which focuses only on table salt products...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-46417-z
更新日期：2019-07-12 00:00:00
abstract：:The controlled preparation of Au nanoparticles (NPs) in the size range of 6 to 22 nm is explored in this study. The Au NPs were prepared by the reduction of tetrachloroauric acid using maltose in the presence of nonionic surfactant Tween 80 at various concentrations to control the size of the resulting Au NPs. With in...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-22976-5
更新日期：2018-03-15 00:00:00
abstract：:Cerebral lateralization is expressed at both the structural and functional levels, and can exist as either a stable characteristic or as a dynamic feature during behavior and development. The anatomically relatively simple olfactory system demonstrates lateralization in both human and non-human animals. Here, we explo...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-15109-x
更新日期：2017-11-06 00:00:00
