AMPA Receptor Auxiliary Proteins of the CKAMP Family.

Abstract:

:α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors are assembled of four core subunits and several additional interacting proteins. Cystine-knot AMPA receptor-modulating proteins (CKAMPs) constitute a family of four proteins that influence the trafficking, subcellular localization and function of AMPA receptors. The four CKAMP family members CKAMP39/shisa8, CKAMP44/shisa9, CKAMP52/shisa6 and CKAMP59/shisa7 differ in their expression profile and their modulatory influence on AMPA receptor function. In this review, I report about recent findings on the differential roles of CKAMP family members.

journal_name

Int J Mol Sci

authors

von Engelhardt J

doi

10.3390/ijms20061460

subject

Has Abstract

pub_date

2019-03-22 00:00:00

issue

6

issn

1422-0067

pii

ijms20061460

journal_volume

20

pub_type

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