New fluoroethyl phenylalanine analogues as potential LAT1-targeting PET tracers for glioblastoma.

abstract：:A numerical method of solving for the elastic wave eigenmodes in acoustic waveguides of arbitrary cross-section is presented. Operating under the assumptions of linear, isotropic materials, it utilizes a finite-difference method on a staggered grid to solve for the acoustic eigenmodes (field and frequency) of the vect...

journal_title：Scientific reports

authors： Dostart N,Liu Y,Popović MA

更新日期：2017-12-13 00:00:00

abstract：:The clinical application of dihydroartemisinin (DHA) has been hampered due to its poor water-solubility. To overcome this hurdle, we devised a novel polymer-drug conjugate, multiarm polyethylene glycol-dihydroartemisinin (PEG-DHA), made by linking DHA with multiarm polyethylene glycol. Herein, we investigated PEG-DHA ...

journal_title：Scientific reports

authors： Dai L,Wang L,Deng L,Liu J,Lei J,Li D,He J

更新日期：2014-07-29 00:00:00

abstract：:Notarchirico (Southern Italy) has yielded the earliest evidence of Acheulean settlement in Italy and four older occupation levels have recently been unearthed, including one with bifaces, extending the roots of the Acheulean in Italy even further back in time. New 40Ar/39Ar on tephras and ESR dates on bleached quartz ...

journal_title：Scientific reports

authors： Moncel MH,Santagata C,Pereira A,Nomade S,Voinchet P,Bahain JJ,Daujeard C,Curci A,Lemorini C,Hardy B,Eramo G,Berto C,Raynal JP,Arzarello M,Mecozzi B,Iannucci A,Sardella R,Allegretta I,Delluniversità E,Terzano R,Dug

更新日期：2020-08-14 00:00:00

abstract：:Organic light-emitting devices and solar cells are devices that create, manipulate, and convert excited states in organic semiconductors. It is crucial to characterize these excited states, or excitons, to optimize device performance in applications like displays and solar energy harvesting. This is complicated if the...

journal_title：Scientific reports

authors： Reineke S,Baldo MA

更新日期：2014-01-21 00:00:00

abstract：:As a two-dimensional material, graphene has attracted increasing attention as heat dissipation material owing to its excellent thermal transport property. In this work, we fabricated sisal nanocrystalline cellulose/functionalized graphene papers (NPGs) with high thermal conductivity by vacuum-assisted self-assembly me...

journal_title：Scientific reports

authors： Ren L,Wang M,Lu S,Pan L,Xiong Z,Zhang Z,Peng Q,Li Y,Yu J

更新日期：2019-03-14 00:00:00

abstract：:Cylindrical shell fused silica resonators coated with 8 axisymmetric Pb(Zr0.53Ti0.47)O3 (PZT) thin film electrodes (thickness ~2 μm) were reported. The resonators were firstly designed and fabricated, then annealed and processed by chemical etching to increase mechanical quality factor (Q factor) of resonators, which ...

journal_title：Scientific reports

authors： Luo Y,Qu T,Cui Y,Pan Y,Yu M,Luo H,Jia Y,Tan Z,Liu J,Zhang B

更新日期：2019-07-01 00:00:00

abstract：:L-amino acid oxidases from snake venoms have been described to possess various biological functions. In this study, we investigated the inflammatory responses induced in vivo and in vitro by CR-LAAO, an L-amino acid oxidase isolated from Calloselasma rhodostoma venom, and its antitumor potential. CR-LAAO induced acute...

journal_title：Scientific reports

authors： Costa TR,Menaldo DL,Zoccal KF,Burin SM,Aissa AF,Castro FA,Faccioli LH,Greggi Antunes LM,Sampaio SV

更新日期：2017-02-16 00:00:00

abstract：:Telomere length (TL) is linked to various age-related diseases, but little is known about telomeres in gestational diabetes mellitus (GDM). We surveyed 509 subjects (113 GDM patients and 396 frequency matched controls) in Nanjing Drum Tower Hospital, Jiangsu province of eastern China. Relative telomere length (RTL) of...

journal_title：Scientific reports

authors： Weng Q,Deng K,Wu F,Gan M,Li J,Dai Y,Jiang Y,Chen J,Dai J,Ma H,Hu Z,Shen H,Du J,Hu Y,Jin G

更新日期：2019-06-11 00:00:00

abstract：:Pre-shared non-local entanglement dramatically simplifies and improves the performance of quantum error correction via entanglement-assisted quantum error-correcting codes (EAQECCs). However, even considering the noise in quantum communication only, the non-local sharing of a perfectly entangled pair is technically im...

journal_title：Scientific reports

authors： Wang Z,Yu S,Fan H,Oh CH

更新日期：2014-11-26 00:00:00

abstract：:Basic leucine zippers (bZIPs) form a large plant transcription factor family. C and S1 bZIP groups can heterodimerize, fulfilling crucial roles in seed development and stress response. S1 sequences also harbor a unique regulatory mechanism, termed Sucrose-Induced Repression of Translation (SIRT). The conservation of b...

journal_title：Scientific reports

authors： Peviani A,Lastdrager J,Hanson J,Snel B

更新日期：2016-07-26 00:00:00

abstract：:Red mud as a waste material is produced in large quantities by the aluminum industry. Heat activation has been used to enhance sorption capacity of red mud for its beneficial reuse as an effective sorbent. In this study, heat-activated red mud (HARM) was investigated for its Cd(II) sorption capacity under various proc...

journal_title：Scientific reports

authors： Yang T,Sheng L,Wang Y,Wyckoff KN,He C,He Q

更新日期：2018-09-10 00:00:00

abstract：:Pachychoroid spectrum diseases have attracted increasing attention, though their pathophysiology has yet to be fully elucidated. In this study, we assessed the vascular diameters of vortex veins in pachychoroid spectrum diseases such as central serous chorioretinopathy (CSC), pachychoroid neovasculopathy without polyp...

journal_title：Scientific reports

authors： Matsumoto H,Hoshino J,Arai Y,Mukai R,Nakamura K,Kikuchi Y,Kishi S,Akiyama H

更新日期：2020-11-11 00:00:00

abstract：:The black rhinoceros is again on the verge of extinction due to unsustainable poaching in its native range. Despite a wide historic distribution, the black rhinoceros was traditionally thought of as depauperate in genetic variation, and with very little known about its evolutionary history. This knowledge gap has hamp...

journal_title：Scientific reports

authors： Moodley Y,Russo IM,Dalton DL,Kotzé A,Muya S,Haubensak P,Bálint B,Munimanda GK,Deimel C,Setzer A,Dicks K,Herzig-Straschil B,Kalthoff DC,Siegismund HR,Robovský J,O'Donoghue P,Bruford MW

更新日期：2017-02-08 00:00:00

abstract：:Cholesterol 25-hydroxylase (CH25H) encodes the enzyme that converts cholesterol to 25-hydroxycholesterol (25-HC). 25-HC has been demonstrated to be involved in the pathogenesis of inflammatory bowel disease. However, the role of CH25H in experimental colitis remains unknown. Dextran sulfate sodium (DSS)-induced coliti...

journal_title：Scientific reports

authors： Sheng N,Ma Z,Zhou Y,Xu J,Gao Y,Fu XY

更新日期：2020-08-28 00:00:00

abstract：:NANOG is a master regulator of embryonic stem cell pluripotency, found to be frequently aberrantly expressed in a variety of cancers, including laryngeal carcinomas. This study investigates for the first time the role of NANOG expression in early stages of laryngeal tumourigenesis and its potential utility as cancer r...

journal_title：Scientific reports

authors： Rodrigo JP,Villaronga MÁ,Menéndez ST,Hermida-Prado F,Quer M,Vilaseca I,Allonca E,Pedregal Mallo D,Astudillo A,García-Pedrero JM

更新日期：2017-09-11 00:00:00

abstract：:Cardiac trabeculae are mesh-like muscular structures within ventricular walls. Subtle perturbations in trabeculation are associated with many congenital heart diseases (CHDs), and complete failure to form trabeculae leads to embryonic lethality. Despite the severe consequence of an absence of trabecular formation, the...

journal_title：Scientific reports

authors： Fleming ND,Samsa LA,Hassel D,Qian L,Liu J

更新日期：2018-06-05 00:00:00

abstract：:ING2 (inhibitor of growth family member 2) is a component of a chromatin-regulatory complex that represses gene expression and is implicated in cellular processes that promote tumor suppression. However, few direct genomic targets of ING2 have been identified and the mechanism(s) by which ING2 selectively regulates ge...

journal_title：Scientific reports

authors： Bua DJ,Martin GM,Binda O,Gozani O

更新日期：2013-01-01 00:00:00

abstract：:Next generation sequencing panels have been developed for hereditary cancer, although there is some debate about their cost-effectiveness compared to exome sequencing. The performance of two panels is compared to exome sequencing. Twenty-four patients were selected: ten with identified mutations (control set) and four...

journal_title：Scientific reports

authors： Feliubadaló L,Tonda R,Gausachs M,Trotta JR,Castellanos E,López-Doriga A,Teulé À,Tornero E,Del Valle J,Gel B,Gut M,Pineda M,González S,Menéndez M,Navarro M,Capellá G,Gut I,Serra E,Brunet J,Beltran S,Lázaro C

更新日期：2017-01-04 00:00:00

abstract：:Diagnostic criteria for pathological gambling and alcohol dependence (AD) include repeated addictive behavior despite severe negative consequences. However, the concept of loss aversion (LA) as a facet of value-based decision making has not yet been used to directly compare these disorders. We hypothesized reduced LA ...

journal_title：Scientific reports

authors： Genauck A,Quester S,Wüstenberg T,Mörsen C,Heinz A,Romanczuk-Seiferth N

更新日期：2017-11-24 00:00:00

abstract：:Intestinal-type sinonasal adenocarcinoma (ITAC) is a rare tumor carrying poor prognosis and needing new treatment options. The aim of this study was to identify actionable gene mutations that can guide new personalized target-specific therapies in ITAC patients. A series of 48 tumor and 27 corresponding germline DNA s...

journal_title：Scientific reports

authors： Sánchez-Fernández P,Riobello C,Costales M,Vivanco B,Cabal VN,García-Marín R,Suárez-Fernández L,López F,Cabanillas R,Hermsen MA,Llorente JL

更新日期：2021-01-26 00:00:00

abstract：:Acoustic energy transfer is a promising energy harvesting technology candidate for implantable biomedical devices. However, it does not show competitive strength for enabling self-powered implantable biomedical devices due to two issues - large size of bulk piezoelectric ultrasound transducers and output power fluctua...

journal_title：Scientific reports

authors： Shi Q,Wang T,Lee C

更新日期：2016-04-26 00:00:00

abstract：:By growing monolayer FeSe on SrTiO3(001) surface, researchers obtain the highest superconducting transition-temperature for iron-based superconductor. Here, we study the antiferromagnetic (AFM) checkerboard monolayer FeSe adsorbed on SrTiO3(001) surface. We show that the system has a considerable charge transfer from ...

journal_title：Scientific reports

authors： Zheng F,Wang Z,Kang W,Zhang P

更新日期：2013-01-01 00:00:00

abstract：:The objective of this study was to determine if Ihh is required for fracture healing. Fibular fracture was created in adult Col2a1-CreERT2; Ihhfl/fl mice. Ihhfl/fl mice received Tamoxifen (TM) to delete Ihh. WT mice received Cyclopamine to inhibit Hh pathway. Callus tissue properties and Ihh pathway were analyzed at 1...

journal_title：Scientific reports

authors： Li S,Xiang C,Wei X,Li H,Li K,Sun X,Wang S,Zhang M,Deng J,Wang X,Li P,Li R,Zhang Y,Wei L

更新日期：2018-07-09 00:00:00

abstract：:Umami taste perception indicates the presence of amino acids, which are essential nutrients. Although the physiology of umami perception has been described in mammals, how insects detect amino acids remains unknown except in Drosophila melanogaster. We functionally characterized a gustatory receptor responding to L-am...

journal_title：Scientific reports

authors： Lim S,Jung J,Yunusbaev U,Ilyasov R,Kwon HW

更新日期：2019-08-12 00:00:00

abstract：:Distance, environmental heterogeneity and local adaptation can strongly influence population structure and connectivity. Understanding how these factors shape the genomic landscape of threatened species is a major goal in conservation genomics and wildlife management. Herein, we use thousands (6,859) of single nucleot...

journal_title：Scientific reports

authors： Sánchez-Ramírez S,Rico Y,Berry KH,Edwards T,Karl AE,Henen BT,Murphy RW

更新日期：2018-07-25 00:00:00

abstract：:The establishment of the infant gut microbiota is a highly dynamic process dependent on extrinsic and intrinsic factors. We characterized the faecal microbiota of 4 breastfed infants and 4 formula-fed infants at 17 consecutive time points during the first 12 weeks of life. Microbiota composition was analysed by a comb...

journal_title：Scientific reports

authors： Timmerman HM,Rutten NBMM,Boekhorst J,Saulnier DM,Kortman GAM,Contractor N,Kullen M,Floris E,Harmsen HJM,Vlieger AM,Kleerebezem M,Rijkers GT

更新日期：2017-08-21 00:00:00

abstract：:A novel characterization technique using both in situ reflection high-energy electron diffraction (RHEED) transmission mode and transmission electron microscopy (TEM) has been developed to investigate the growth behaviour of semiconductor nanostructures. RHEED employed in transmission mode enables the acquisition of s...

journal_title：Scientific reports

authors： Jo J,Tchoe Y,Yi GC,Kim M

更新日期：2018-01-26 00:00:00

abstract：:The origin of the enantio- and regioselectivity of ring-opening reaction of oxabicyclic alkenes catalyzed by rhodium/Josiphos has been examined using M06-2X density functional theory(DFT). DFT calculations predict a 98% ee for the enantioselectivity and only the 1,2-trans product as one regio- and diastereomer, in exc...

journal_title：Scientific reports

authors： Qi ZH,Zhang Y,Gao Y,Zhang Y,Wang XW,Wang Y

更新日期：2017-01-11 00:00:00

abstract：:Previously, long-term effects on body weight and reproductive performance have been demonstrated in the chicken model of prenatal protein undernutrition by albumen removal. Introduction of such persistent alterations in phenotype suggests stable changes in gene expression. Therefore, a genome-wide screening of the hep...

journal_title：Scientific reports

authors： Willems E,Guerrero-Bosagna C,Decuypere E,Janssens S,Buyse J,Buys N,Jensen P,Everaert N

更新日期：2016-02-10 00:00:00

abstract：:Mucociliary clearance is a biomechanical mechanism of airway protection. It consists of the active transport along the bronchial tree of the mucus, a fluid propelled by the coordinated beating of a myriad of cilia on the epithelial surface of the respiratory tract. The physics of mucus transport is poorly understood b...

journal_title：Scientific reports

authors： Khelloufi MK,Loiseau E,Jaeger M,Molinari N,Chanez P,Gras D,Viallat A

更新日期：2018-02-05 00:00:00