Neutrophils Dampen Adaptive Immunity in Brucellosis.

abstract：:The serum opacity factor (SOF) of Streptococcus pyogenes is a serotyping tool and pathogenesis factor. Using SOF-coated latex beads in cell adherence assays and antiserum directed against SOF in S. pyogenes-HEp-2 cell adherence inhibition experiments, we demonstrate SOF involvement in the fibronectin-mediated adherenc...

journal_title：Infection and immunity

authors： Oehmcke S,Podbielski A,Kreikemeyer B

更新日期：2004-07-01 00:00:00

abstract：:Erythrocytic malaria parasites degrade hemoglobin as a principal source of amino acids for parasite protein synthesis. We have previously shown that a Plasmodium falciparum trophozoite cysteine proteinase, now termed falcipain, is required for hemoglobin degradation, and we have hypothesized that this proteinase is re...

journal_title：Infection and immunity

authors： Salas F,Fichmann J,Lee GK,Scott MD,Rosenthal PJ

更新日期：1995-06-01 00:00:00

abstract：:Serological tests used in current brucellosis eradication schemes, such as bacterial tube agglutination, do not readily distinguish between infected animals and those immunized with strain 19 or 45/20 Brucella abortus vaccines. In this study, sera from naturally infected cattle were used to identify serologically impo...

journal_title：Infection and immunity

authors： Raybould TJ,Chantler S

更新日期：1980-08-01 00:00:00

abstract：:We have investigated the ability of two species of streptococci isolated from the human oral cavity (Streptococcus mutans NCTC 10449 and Streptococcus sobrinus SL-1) to metabolize N-acetylglucosamine (GlcNAc), a naturally occurring amino sugar present in saliva and human glycoproteins, when provided as the sole fermen...

journal_title：Infection and immunity

authors： Homer KA,Patel R,Beighton D

更新日期：1993-01-01 00:00:00

abstract：:Kinetic, microscopic, and biochemical studies show that virulent Ti (tumor inducing)-plasmid-containing strains of Agrobacterium attach to normal tobacco and carrot tissue culture cells. Kinetic studies showed that virulent strains of A. tumefaciens attach to the plant tissue culture cells in increasing numbers during...

journal_title：Infection and immunity

authors： Matthysse AG,Wyman PM,Holmes KV

更新日期：1978-11-01 00:00:00

abstract：:Ureaplasma urealyticum is a common commensal of the female lower urogenital tract, yet it has been shown to be an important cause of chorioamnion infection, respiratory and central nervous system disease, and death in premature infants. It has been suggested that only certain serovars are capable of producing invasive...

journal_title：Infection and immunity

authors： Zheng X,Teng LJ,Watson HL,Glass JI,Blanchard A,Cassell GH

更新日期：1995-03-01 00:00:00

abstract：:Herpes simplex virus (HSV) infection of mouse liver after partial hepatectomy was studied. Partial hepatectomy resulted in the rapid onset of cellular DNA synthesis and the appearance of many mitotic figures (peak, 3 days after surgery). Similar changes were not seen in control animals. After partial hepatectomy, the ...

journal_title：Infection and immunity

authors： Fang ZY,Tenser RB,Rapp F

更新日期：1983-10-01 00:00:00

abstract：:Vaccination has been proposed for the prevention of disease due to enterohemorrhagic Escherichia coli (EHEC), but the immune response following human infection, including the choice of potential antigens, has not been well characterized. To study this, sera were obtained from five pediatric patients with acute diarrhe...

journal_title：Infection and immunity

authors： Li Y,Frey E,Mackenzie AM,Finlay BB

更新日期：2000-09-01 00:00:00

abstract：:Transposon Tn916 was used to insertionally inactivate a coaggregation-relevant locus of Streptococcus gordonii DL1 (Challis). One mutant (F11) was isolated that lost the ability to coaggregate with the streptococcal partners of DL1 but retained the ability to coaggregate with partners belonging to other genera. A prob...

journal_title：Infection and immunity

authors： Whittaker CJ,Clemans DL,Kolenbrander PE

更新日期：1996-10-01 00:00:00

abstract：:Children are more resistant to gingivitis than are adults. To determine possible differences in their periodontal floras, an experimental gingivitis study, identical in design to one reported earlier with young adults, was conducted with four 4- to 6-year-old children. The incidence of sites that developed gingival in...

journal_title：Infection and immunity

authors： Moore WE,Holdeman LV,Smibert RM,Cato EP,Burmeister JA,Palcanis KG,Ranney RR

更新日期：1984-10-01 00:00:00

abstract：:The fungus Cryptococcus neoformans has emerged as a major cause of meningoencephalitis worldwide. Host response to the fungus involves both innate and adaptive immunity, but fungal genes that modulate these processes are poorly understood. Previous studies demonstrated attenuated virulence of a mutant of a virulence-a...

journal_title：Infection and immunity

authors： Qiu J,Olszewski MA,Williamson PR

更新日期：2013-03-01 00:00:00

abstract：:Nasopharyngeal colonization is a necessary first step in the pathogenesis of Streptococcus pneumoniae. Using isolates containing defined mutations in the S. pneumoniae capsule locus, we found that expression of the capsular polysaccharide is essential for colonization by the type 2 strain D39 and the type 3 strains A6...

journal_title：Infection and immunity

authors： Magee AD,Yother J

更新日期：2001-06-01 00:00:00

abstract：:The phenotypic and functional changes of glycolipid presented by CD1d(glycolipid/CD1d) specific Valpha14+ T cells in the liver of mice at early stages of bacterial infection were investigated. After Listeria monocytogenes infection or interleukin-12 (IL-12) treatment, alpha-galactosylceramide/CD1d tetramer-reactive (a...

journal_title：Infection and immunity

authors： Emoto M,Yoshizawa I,Emoto Y,Miamoto M,Hurwitz R,Kaufmann SH

更新日期：2006-10-01 00:00:00

abstract：:Modulation of cytosolic (intracellular) Ca(2+) concentration (Ca(i)) may be an important host response when airway epithelial cells are exposed to Pseudomonas aeruginosa. We measured Ca(i) in Calu-3 cells exposed from the apical or basolateral surface to cytotoxic and noncytotoxic strains of P. aeruginosa. Apical addi...

journal_title：Infection and immunity

authors： Jacob T,Lee RJ,Engel JN,Machen TE

更新日期：2002-11-01 00:00:00

abstract：:The bacterial pathogen Listeria monocytogenes causes foodborne systemic disease in pregnant women, which can lead to preterm labor, stillbirth, or severe neonatal disease. Colonization of the maternal decidua appears to be an initial step in the maternal component of the disease as well as bacterial transmission to th...

journal_title：Infection and immunity

authors： Rizzuto G,Tagliani E,Manandhar P,Erlebacher A,Bakardjiev AI

更新日期：2017-07-19 00:00:00

abstract：:Antibody rises to various virus subcomponents were measured by enzyme-linked immunosorbent assay in the paired sera of volunteers experimentally infected with human coronavirus 229E group viruses. Most of the antibody made during infection was directed against the virus surface projections, with only small amounts of ...

journal_title：Infection and immunity

authors： Macnaughton MR,Hasony HJ,Madge MH,Reed SE

更新日期：1981-03-01 00:00:00

abstract：:To test the hypothesis that the Staphylococcus aureus enterotoxin gene cluster (egc) can generate new enterotoxin genes by recombination, we analyzed the egc locus in a broad panel of 666 clinical isolates of S. aureus. egc was present in 63% of isolates, confirming its high prevalence. The archetypal organization of ...

journal_title：Infection and immunity

authors： Thomas DY,Jarraud S,Lemercier B,Cozon G,Echasserieau K,Etienne J,Gougeon ML,Lina G,Vandenesch F

更新日期：2006-08-01 00:00:00

abstract：:Human multidrug efflux transporters are known for their ability to extrude antibiotics and toxic compounds out of cells, yet accumulating data indicate they have additional functions in diverse physiological processes not related to drug efflux. Here, we show that the human multidrug transporter P-glycoprotein (P-gp) ...

journal_title：Infection and immunity

authors： Sigal N,Kaplan Zeevi M,Weinstein S,Peer D,Herskovits AA

更新日期：2015-06-01 00:00:00

abstract：:Three open reading frames (ORFs) were identified by a genome walking strategy in the genomes of serotype M49 group A streptococcal (GAS) strains CS101 and 591. These ORFs were located between the mga core regulon and the dipeptide permease operon. The deduced amino acid (aa) sequences contained signature sequences ind...

journal_title：Infection and immunity

authors： Elsner A,Kreikemeyer B,Braun-Kiewnick A,Spellerberg B,Buttaro BA,Podbielski A

更新日期：2002-09-01 00:00:00

abstract：:Cultures of Serpulina pilosicoli 95/1000, isolated from a pig with porcine intestinal spirochetosis (PIS), and S. pilosicoli WesB, isolated from an Aboriginal child with diarrhea, were used to infect 5-week-old newly weaned pigs. Four of 12 pigs infected with strain 95/1000 and 2 of 12 pigs infected with strain WesB b...

journal_title：Infection and immunity

authors： Trott DJ,Huxtable CR,Hampson DJ

更新日期：1996-11-01 00:00:00

abstract：:Streptococcus pneumoniae is a major cause of pneumonia and meningitis. Airway colonization is a necessary precursor to disease, but little is known about how the bacteria establish and maintain colonization. Carbohydrates are required as a carbon source for pneumococcal growth and, therefore, for colonization. Free ca...

journal_title：Infection and immunity

authors： Marion C,Burnaugh AM,Woodiga SA,King SJ

更新日期：2011-03-01 00:00:00

abstract：:Escherichia coli strains produce at least two heat-stable enterotoxins, STa and STb. STa is well known to be important in the pathogenesis of human diarrheal disease; the role of STb has not been defined. Fifty-two E. coli strains recovered from human diarrheal illness in northeast Brazil or Bangladesh were examined i...

journal_title：Infection and immunity

authors： Weikel CS,Tiemens KM,Moseley SL,Huq IM,Guerrant RL

更新日期：1986-04-01 00:00:00

abstract：:The ethanol-insoluble product formed from sucrose by purified enzyme encoded by the gtfA gene from Streptococcus mutans, expressed in recombinant Escherichia coli, was analyzed by 13C and 31P nuclear magnetic resonance. The product was identified as alpha-D-glucose-1-phosphate, and it was concluded that the GTF-A enzy...

journal_title：Infection and immunity

authors： Russell RR,Mukasa H,Shimamura A,Ferretti JJ

更新日期：1988-10-01 00:00:00

abstract：:The relationship between the selective abilities of bacteria to adhere and their predilections for colonizing different mammalian hosts was investigated by using bacteria indigenous to the tongue dorsum of humans and rats as models. Streptococcus salivarius and S. sanguis averaged 22.6 and 2.8%, respectively, of the c...

journal_title：Infection and immunity

authors： Gibbons RJ,Spinell DM,Skobe Z

更新日期：1976-01-01 00:00:00

abstract：:A recent study demonstrated that polyclonal antibodies to Rickettsia conorii and monoclonal antibodies to outer membrane proteins A (OmpA) and B (OmpB) provided effective, Fc-dependent, passive immunity, even in severe combined immunodeficient mice with an established infection. In order to determine the mechanism of ...

journal_title：Infection and immunity

authors： Feng HM,Whitworth T,Popov V,Walker DH

更新日期：2004-06-01 00:00:00

abstract：:The coaggregation-defective (COG-) mutant Actinomyces viscosus T14V(PK455), which is unable to participate in lactose-sensitive adherence, and its COG+ parent were compared to structurally define the mutational loss of cell-associated lectin activity. Immunoelectrophoretic comparisons of crude extracts or isolated fim...

journal_title：Infection and immunity

authors： Cisar JO,Curl SH,Kolenbrander PE,Vatter AE

更新日期：1983-05-01 00:00:00

abstract：:Streptococcus pyogenes is one of the most frequent human pathogens. Recent studies have identified dendritic cells (DCs) as important contributors to host defense against S. pyogenes. The objective of this study was to identify the receptors involved in immune recognition of S. pyogenes by DCs. To determine whether To...

journal_title：Infection and immunity

authors： Loof TG,Goldmann O,Medina E

更新日期：2008-06-01 00:00:00

abstract：:Previous experimentation has highlighted a number of difficulties in the development of carrier-based bivalent vaccines (J.-F. Viret and D. Favre, Biologicals 22:361-372, 1994) In an attempt to obviate these carrier strains. Toward this aim, a series of defined rfbInaba deletion (delta rfbInaba) mutants of the cholera...

journal_title：Infection and immunity

authors： Favre D,Cryz SJ Jr,Viret JF

更新日期：1996-02-01 00:00:00

abstract：:Parasite antigens which bind to host cell molecules of approximately 32 and 34 kilodaltons (kDa) were identified in supernatant fluids obtained from axenic cultures of Trypanosoma cruzi. These parasite components were first detected in culture supernatants obtained after 2 weeks in culture. Immunoblot analysis of cult...

journal_title：Infection and immunity

authors： Davis CD,Kuhn RE

更新日期：1990-06-01 00:00:00

abstract：:Earlier work had shown that a collection of anaerobic bacteria, in conjunction with facultative anaerobes, may be implanted into germfree mice, thereby rendering the animals "normal" with respect to a variety of parameters tested. The present experiments indicate that a different collection of anaerobic bacteria, isol...

journal_title：Infection and immunity

authors： Freter R,Abrams GD

更新日期：1972-08-01 00:00:00