Cold stress on Araucaria angustifolia embryogenic cells results in oxidative stress and induces adaptation: implications for conservation and propagation.

Abstract:

:Araucaria angustifolia (Bert.) O. Kuntze is a species critically endangered of extinction and its development and propagation is strongly affected by abiotic stress. We have previously shown the activation of uncoupling protein in A. angustifolia embryogenic stem cells subjected to cold stress. Now, we have furthered those studies by exposing these cells to cold stress (4 ± 1 °C for either 24 or 48 h) and evaluating parameters associated with oxidative stress and alterations in the cellular and mitochondrial responses. Cold stress affect the H2O2 levels and lipid peroxidation increased after both stress condition, an effect associated with the decrease in the activities of peroxidases, catalase and ascorbate/dehydroascorbate ratio. On the other hand, the activities of ascorbate peroxidase, monodehydroascorbate and dehydroascorbate reductases increased as an indication of adaptation. Another important impact of cold stress conditions was the decrease of external alternative NAD(P)H dehydrogenases activity and the increase of mitochondrial mass. These results show that cold stress induces oxidative stress in A. angustifolia embryogenic cells, which results in activation of the glutathione-ascorbate cycle as a compensation for the decrease in the activities of catalase, peroxidases, and external NAD(P)H dehydrogenases. Our results contribute to the understanding of the pathways that gymnosperms employ to overcome oxidative stress, which must be explored in order to improve the methods of conservation and propagation of A. angustifolia.

journal_name

Free Radic Res

journal_title

Free radical research

authors

Dorigan de Matos Furlanetto AL,Valente C,Martinez GR,Merlin Rocha ME,Maurer JBB,Cadena SMSC

doi

10.1080/10715762.2018.1548767

subject

Has Abstract

pub_date

2019-01-01 00:00:00

pages

45-56

issue

1

eissn

1071-5762

issn

1029-2470

journal_volume

53

pub_type

杂志文章
  • Levels of 8-oxo-dGsn and 8-oxo-Gsn in random urine are consistent with 24 h urine in healthy subjects and patients with renal disease.

    abstract::Oxidatively generated damage to nucleic acids may play an important role in the pathophysiological processes of a variety of diseases. 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxo-dGsn) and 8-oxo-7,8-dihydroguanosine (8-oxo-Gsn) are oxidatively generated products of DNA and RNA, respectively. Our previous studies have s...

    journal_title:Free radical research

    pub_type: 杂志文章

    doi:10.1080/10715762.2017.1346249

    authors: Mao YH,Weng QH,Xu LN,Li XY,Zhao B,Sun Y,Nie JJ,Hu JH,Zhou Q,Zhang LQ,Guo J,Zuo MZ,Ito S,Cai JP

    更新日期:2017-06-01 00:00:00

  • Coenzyme Q10 as a possible treatment for neurodegenerative diseases.

    abstract::Coenzyme Q10 (CoQ10) is an essential cofactor of the electron transport gene as well as an important antioxidant, which is particularly effective within mitochondria. A number of prior studies have shown that it can exert efficacy in treating patients with known mitochondrial disorders. We investigated the potential u...

    journal_title:Free radical research

    pub_type: 杂志文章,评审

    doi:10.1080/10715760290021315

    authors: Beal MF

    更新日期:2002-04-01 00:00:00

  • Mechanism of radiation-induced reactions in aqueous solution of coumarin-3-carboxylic acid: effects of concentration, gas and additive on fluorescent product yield.

    abstract::The radiation-induced reactions of a water-soluble coumarin derivative, coumarin-3-carboxyl acid (C3CA), have been investigated in aqueous solutions by pulse radiolysis with a 35 MeV electron beam, final product analysis following (60)Co γ-irradiations and deterministic model simulations. Pulse radiolysis revealed tha...

    journal_title:Free radical research

    pub_type: 杂志文章

    doi:10.3109/10715762.2012.684879

    authors: Yamashita S,Baldacchino G,Maeyama T,Taguchi M,Muroya Y,Lin M,Kimura A,Murakami T,Katsumura Y

    更新日期:2012-07-01 00:00:00

  • Thioredoxin, an anti-oxidant protein, protects mouse embryos from oxidative stress-induced developmental anomalies.

    abstract::During the early postimplantation period, rodent embryos survive in a relatively anaerobic environment in utero and are vulnerable to a high oxygen pressure. They become resistant to oxygen stress when they are exposed to a higher oxygen pressure after the uteroplacental circulation is established. However, it is unkn...

    journal_title:Free radical research

    pub_type: 杂志文章

    doi:10.1080/1071576021000006626

    authors: Kobayashi-Miura M,Nakamura H,Yodoi J,Shiota K

    更新日期:2002-09-01 00:00:00

  • Cyp4a14 overexpression induced by hyperoxia in female CBA mice as a possible contributor of increased resistance to oxidative stress.

    abstract::The beneficial effects of hyperoxia have been noted in treatment of several diseases and pathological states. However, the excessive production of ROS under hyperoxic conditions can directly damage cellular macromolecules if the imbalance in antioxidant status exists. Cytochrome P450 (Cyp) 4a14 has an important role i...

    journal_title:Free radical research

    pub_type: 杂志文章

    doi:10.3109/10715760903390820

    authors: Sobocanec S,Balog T,Sarić A,Sverko V,Zarković N,Gasparović AC,Zarković K,Waeg G,Macak-Safranko Z,Kusić B,Marotti T

    更新日期:2010-02-01 00:00:00

  • Arctigenin suppresses transforming growth factor-β1-induced expression of monocyte chemoattractant protein-1 and the subsequent epithelial-mesenchymal transition through reactive oxygen species-dependent ERK/NF-κB signaling pathway in renal tubular epithe

    abstract::Transforming growth factor-β1 (TGF-β1) induces expression of the proinflammatory and profibrotic cytokine monocyte chemoattractant protein-1 (MCP-1) in tubular epithelial cells (TECs) and thereby contributes to the tubular epithelial-mesenchymal transition (EMT), which in turn leads to the progression of tubulointerst...

    journal_title:Free radical research

    pub_type: 杂志文章

    doi:10.3109/10715762.2015.1038258

    authors: Li A,Wang J,Zhu D,Zhang X,Pan R,Wang R

    更新日期:2015-01-01 00:00:00

  • Pharmacokinetics and metabolism of dietary flavonoids in humans.

    abstract::Flavonoids are components of fruit and vegetables that may be beneficial in the prevention of disease such as cancer and cardiovascular diseases. Their beneficial effects will be dependent upon their uptake and disposition in tissues and cells. The metabolism and pharmacokinetics of flavonoids has been an area of acti...

    journal_title:Free radical research

    pub_type: 杂志文章,评审

    doi:10.1080/10715760410001727858

    authors: Manach C,Donovan JL

    更新日期:2004-08-01 00:00:00

  • Hydroxyl radical scavenging activity of nonsteroidal anti-inflammatory drugs.

    abstract::The hydroxyl radical (.OH)-scavenging activity of d-2-[4-(3-methyl-2-thienyl)phenyl]propionic acid (M-5011), a novel nonsteroidal anti-inflammatory drug (NSAID), and that of several other NSAIDs were investigated by the hyaluronic acid (HA) degradation method and the electron spin resonance (ESR) spin-trapping techniq...

    journal_title:Free radical research

    pub_type: 杂志文章

    doi:10.3109/10715769709065781

    authors: Kataoka M,Tonooka K,Ando T,Imai K,Aimoto T

    更新日期:1997-10-01 00:00:00

  • In vitro antioxidant capacity and antigenotoxic properties of protoporphyrin and structurally related tetrapyrroles.

    abstract::The antioxidant properties of protoporphyrin IX and related tetrapyrroles are poorly characterized. Therefore, eight tetrapyrroles, five of which are produced in vivo, were tested to assess their antioxidant capacities in the Salmonella reverse mutation, TEAC, FRAP and ORAC assays. Tertiary-butyl hydroperoxide (tert-B...

    journal_title:Free radical research

    pub_type: 杂志文章

    doi:10.3109/10715762.2012.715371

    authors: Mölzer C,Huber H,Steyrer A,Ziesel G,Ertl A,Plavotic A,Wallner M,Bulmer AC,Wagner KH

    更新日期:2012-11-01 00:00:00

  • Attenuation of oxidative hemolysis of human red blood cells by the natural phenolic compound, allylpyrocatechol.

    abstract::The protecting ability of the Piper betle leaves-derived phenol, allylpyrocatechol (APC) against AAPH-induced membrane damage of human red blood cells (RBCs) was investigated. Compared to control, AAPH (50 mM) treatment resulted in significant hemolysis (55%, p < 0.01), associated with increased malondialdehyde (MDA) ...

    journal_title:Free radical research

    pub_type: 杂志文章

    doi:10.3109/10715762.2013.816847

    authors: Iyer MK,Nayak R,Colah R,Chattopadhyay S

    更新日期:2013-09-01 00:00:00

  • Oxidative stress-inducible proteins in macrophages.

    abstract::Macrophages produce reactive oxygen species such as O2-, H2O2 and *OH that contribute to the pathogenesis of diseases such as inflammation and atherosclerosis. The cells have multiple defense systems against those reactive oxygen species, and we describe here such an oxidative stress-inducible defense system. Upon exp...

    journal_title:Free radical research

    pub_type: 杂志文章,评审

    doi:10.1080/10715769900300921

    authors: Ishii T,Itoh K,Sato H,Bannai S

    更新日期:1999-10-01 00:00:00

  • Differential response of lymphocytes and neutrophils to high intensity physical activity and to vitamin C diet supplementation.

    abstract::We have determined the effects of chronic vitamin C intake on neutrophil and lymphocyte antioxidant defences during the acute phase immune response induced by intense exercise. Blood samples were taken from 16 voluntary athletes in basal conditions, both immediately after and 1 h after a duathlon competition. Sportsme...

    journal_title:Free radical research

    pub_type: 杂志文章

    doi:10.1080/1071576031000150454

    authors: Tauler P,Aguiló A,Gimeno I,Noguera A,Agustí A,Tur JA,Pons A

    更新日期:2003-09-01 00:00:00

  • Hydrogen peroxide and the proliferation of BHK-21 cells.

    abstract::Intracellular levels of H2O2 in BHK-21 cells are not static but decline progressively with cell growth. Exposure of cells to inhibitors of catalase, or glutathione peroxidase, not only diminishes this decline but also depresses rates of cell proliferation, suggesting important growth regulatory roles for those antioxi...

    journal_title:Free radical research

    pub_type: 杂志文章

    doi:10.3109/10715769509065268

    authors: Burdon RH,Alliangana D,Gill V

    更新日期:1995-11-01 00:00:00

  • Biomarkers in breath condensate: a promising new non-invasive technique in free radical research.

    abstract::Oxidative stress is associated with a range of inflammatory lung diseases including asthma, adult respiratory distress syndrome, idiopathic pulmonary fibrosis, pneumonia, lung transplantation, chronic obstructive pulmonary disease, cystic fibrosis, bronchiectasis and lung cancer. Increased concentrations of reactive o...

    journal_title:Free radical research

    pub_type: 杂志文章,评审

    doi:10.1080/10715760310001623331

    authors: Rahman I,Kelly F

    更新日期:2003-12-01 00:00:00

  • Molecular and biochemical investigations of inborn errors of metabolism-altered redox homeostasis in branched-chain amino acid disorders, organic acidurias, and homocystinuria.

    abstract::India, resembling other developing nations, is confronting a hastening demographic switch to non-communicable diseases. Inborn errors of metabolism (IEM) constitute a varied heterogeneous group of disorders with variable clinical appearance, primarily in the pediatric populace. Congenital deformities and genetic disor...

    journal_title:Free radical research

    pub_type: 杂志文章

    doi:10.1080/10715762.2021.1877286

    authors: Ray SK,Mukherjee S

    更新日期:2021-01-27 00:00:00

  • Carotenoids induce apoptosis in the T-lymphoblast cell line Jurkat E6.1.

    abstract::Epidemiologically, a high-carotenoid intake via a fruit- and vegetable-rich diet is associated with a decreased risk of various forms of cancer. The mechanisms by which carotenoids exert this protective effect are controversial. In this study, we examined the potency of a range of carotenoids commonly found in human p...

    journal_title:Free radical research

    pub_type: 杂志文章

    doi:10.1080/10715760290032539

    authors: Müller K,Carpenter KL,Challis IR,Skepper JN,Arends MJ

    更新日期:2002-07-01 00:00:00

  • Myeloperoxidase deficiency induces MIP-2 production via ERK activation in zymosan-stimulated mouse neutrophils.

    abstract::Myeloperoxidase (MPO), a major constituent of neutrophils, catalyzes the production of hypochlorous acid (HOCl) from hydrogen peroxide (H2O2) and chloride anion. We have previously reported that MPO-deficient (MPO(-/-)) neutrophils produce greater amount of macrophage inflammatory protein-2 (MIP-2) in vitro than do wi...

    journal_title:Free radical research

    pub_type: 杂志文章

    doi:10.3109/10715762.2013.778990

    authors: Tateno N,Matsumoto N,Motowaki T,Suzuki K,Aratani Y

    更新日期:2013-05-01 00:00:00

  • Oxidative stress to human lymphocytes by xanthine oxidoreductase activity.

    abstract::The in vitro toxicity of the reactive oxygen species generating enzyme xanthine oxidoreductase (XOR) to human peripheral blood lymphocytes was studied after stimulation with phytohaemoagglutinin or anti-CD3/CD28 antibodies. Apoptosis and necrosis were induced by the XOR/hypoxanthine system in a time- and concentration...

    journal_title:Free radical research

    pub_type: 杂志文章

    doi:10.1080/10715760100301191

    authors: Battelli MG,Musiani S,Tazzari PL,Stirpe F

    更新日期:2001-12-01 00:00:00

  • HO-1 mitigates acute kidney injury and subsequent kidney-lung cross-talk.

    abstract::Ischemia-reperfusion injury (IRI) is a leading cause of acute kidney injury (AKI), which contributes to the development of chronic kidney disease (CKD). IRI-induced AKI releases proinflammatory cytokines (e.g. IL-1β, TNF-α, IL-6) that induce a systemic inflammatory response, resulting in proinflammatory cells recruitm...

    journal_title:Free radical research

    pub_type: 杂志文章

    doi:10.1080/10715762.2019.1668936

    authors: Rossi M,Delbauve S,Roumeguère T,Wespes E,Leo O,Flamand V,Le Moine A,Hougardy JM

    更新日期:2019-10-01 00:00:00

  • Local and systemic oxidant/antioxidant status before and during lung cancer radiotherapy.

    abstract::To examine local and systemic oxidative status of lung cancer (LC) and oxidant effects of radiotherapy (RT), this study evaluated antioxidants and markers of oxidative and nitrosative stress in bronchoalveolar lavage (BAL) fluid and in the blood of 36 LC patients and 36 non-cancer controls at baseline and during and a...

    journal_title:Free radical research

    pub_type: 杂志文章

    doi:10.1080/10715760902942824

    authors: Crohns M,Saarelainen S,Kankaanranta H,Moilanen E,Alho H,Kellokumpu-Lehtinen P

    更新日期:2009-07-01 00:00:00

  • Adaptation to multiday ozone exposure is associated with a sustained increase of bronchoalveolar uric acid.

    abstract::The phenomenon of ozone tolerance is described, but the underlying mechanisms remain unknown. We tested whether adaptation to multiday ozone exposure was related to an upregulated pulmonary antioxidant defence. Six calves were exposed to 0.75 ppm ozone, 12 h day(-1) for seven consecutive days. Pulmonary function tests...

    journal_title:Free radical research

    pub_type: 杂志文章

    doi:10.1080/10715760210169

    authors: Kirschvink N,Fiévez L,Bureau F,Degand G,Maghuin-Rogister G,Smith N,Art T,Lekeux P

    更新日期:2002-01-01 00:00:00

  • Detection of a stable free radical in the B2 subunit of the manganese ribonucleotide reductase (Mn-RRase) of Corynebacterium ammoniagenes.

    abstract::Ribonucleotide reductases catalyze the irreversible reductive formation of 2'-deoxyribonucleotides required for DNA replication and cell proliferation, and a radical mechanism was assumed to be involved in this reaction. In order to search for a radical in the aerobic manganese ribonucleotide reductase (Mn-RRase) by e...

    journal_title:Free radical research

    pub_type: 杂志文章

    doi:10.3109/10715769609088046

    authors: Griepenburg U,Lassmann G,Auling G

    更新日期:1996-06-01 00:00:00

  • Plasma reactive carbonyl species: Potential risk factor for hypertension.

    abstract::To study the role of oxidative stress in hypertension and pre-hypertension, this study analysed plasma levels of reactive carbonyl species (RCS) in 1204 Chinese Han adults. Results showed a statistically significant positive correlation (p < 0.001) between blood pressure and plasma RCS levels with or without being adj...

    journal_title:Free radical research

    pub_type: 杂志文章

    doi:10.3109/10715762.2011.557723

    authors: Chen K,Xie F,Liu S,Li G,Chen Y,Shi W,Hu H,Liu L,Yin D

    更新日期:2011-05-01 00:00:00

  • The Cu/Zn superoxide dismutase +35A/C (rs2234694) variant correlates with altered levels of protein carbonyls and glutathione and associates with severity of COPD in a Tunisian population.

    abstract::Chronic obstructive pulmonary disease (COPD) is a major cause of mortality that has been associated with inflammation and oxidative stress. The purpose of the present case-control study was to determine the relationships between oxidative stress-related genetic variants and the risk and severity of COPD, as well as, t...

    journal_title:Free radical research

    pub_type: 杂志文章

    doi:10.1080/10715762.2019.1572888

    authors: Ben Anes A,Ben Nasr H,Garrouche A,Bchir S,Dhaouefi Z,Chabchoub E,Tabka Z,Chahed K

    更新日期:2019-03-01 00:00:00

  • The main components of St John's Wort inhibit low-density lipoprotein atherogenic modification: a beneficial "side effect" of an OTC antidepressant drug?

    abstract::Hypericin and pseudohypericin are polycyclic-phenolic structurally related compounds found in Hypericum perforatum L. (St John's wort). As hypericin has been found to bind to LDL one may assume that it can act as antioxidant of LDL lipid oxidation, a property which is of prophylactic/therapeutic interest regarding ath...

    journal_title:Free radical research

    pub_type: 杂志文章

    doi:10.1080/10715760600978831

    authors: Laggner H,Schreier S,Hermann M,Exner M,Mühl A,Gmeiner BM,Kapiotis S

    更新日期:2007-02-01 00:00:00

  • Protective effects of Alpha-lipoic acid on MeHg-induced oxidative damage and intracellular Ca(2+) dyshomeostasis in primary cultured neurons.

    abstract::Methylmercury (MeHg) is one of the ubiquitous environmental toxicant that leads to long-lasting neurological deficits in animals and humans. However, the mechanisms of MeHg-induced neuronal cell death are incompletely understood. Treatment of neuronal cells with MeHg (0-2 μM) for 0.5-12 h, or pretreated with LA (12.5-...

    journal_title:Free radical research

    pub_type: 杂志文章

    doi:10.3109/10715762.2016.1152362

    authors: Yang T,Xu Z,Liu W,Xu B,Deng Y

    更新日期:2016-01-01 00:00:00

  • Iron prevents ascorbic acid (vitamin C) induced hydrogen peroxide accumulation in copper contaminated drinking water.

    abstract::Ascorbic acid (vitamin C) induced hydrogen peroxide (H(2)O(2)) formation was measured in household drinking water and metal supplemented Milli-Q water by using the FOX assay. Here we show that ascorbic acid readily induces H(2)O(2) formation in Cu(II) supplemented Milli-Q water and poorly buffered household drinking w...

    journal_title:Free radical research

    pub_type: 杂志文章

    doi:10.1080/10715760500249861

    authors: Jansson PJ,Lindqvist C,Nordström T

    更新日期:2005-11-01 00:00:00

  • Can antioxidant's reactive oxygen species (ROS) scavenging capacity contribute to aged seed recovery? Contrasting effect of melatonin, ascorbate and glutathione on germination ability of aged maize seeds.

    abstract::It is well known that antioxidants such as AA (reduced ascorbate), glutathione (GSH) (reduced glutathione) and melatonin can delay seed ageing. Can they recover aged seed? Artificial aged maize seeds were obtained and their reduced germination rate (GR) and high lipid peroxidation were recorded. Exogenous melatonin wa...

    journal_title:Free radical research

    pub_type: 杂志文章

    doi:10.1080/10715762.2017.1375099

    authors: Deng B,Yang K,Zhang Y,Li Z

    更新日期:2017-10-01 00:00:00

  • Coenzyme Q10 serves to couple mitochondrial oxidative phosphorylation and fatty acid β-oxidation, and attenuates NLRP3 inflammasome activation.

    abstract::Multiple acyl-CoA dehydrogenase deficiency (MADD), an autosomal recessive metabolic disorder of fatty acid metabolism, is mostly caused by mutations in the ETFA, ETFB or ETFDH genes that result in dysfunctions in electron transfer flavoprotein (ETF) or electron transfer flavoprotein-ubiquinone dehydrogenase (ETFDH). I...

    journal_title:Free radical research

    pub_type: 杂志文章

    doi:10.1080/10715762.2018.1500695

    authors: Chokchaiwong S,Kuo YT,Lin SH,Hsu YC,Hsu SP,Liu YT,Chou AJ,Kao SH

    更新日期:2018-12-01 00:00:00

  • Mth1 deficiency provides longer survival upon intraperitoneal crocidolite injection in female mice.

    abstract::Exposure to asbestos fiber is central to mesothelial carcinogenesis. Recent sequencing studies on human and rodent malignant mesothelioma (MM) revealed frequently mutated genes, including CDKN2A, BAP1 and NF2. Crocidolite directly or indirectly catalyses the generation of hydroxyl radicals, which appears to be the maj...

    journal_title:Free radical research

    pub_type: 杂志文章

    doi:10.1080/10715762.2020.1743285

    authors: Funahashi S,Okazaki Y,Akatsuka S,Takahashi T,Sakumi K,Nakabeppu Y,Toyokuni S

    更新日期:2020-03-01 00:00:00