Abstract:
Background:Fluid resuscitation is critical to perioperative maintenance of adequate preload and cardiac output after cardiac surgery. Liberal use of saline, however, is reportedly associated with an increased risk of acute kidney injury (AKI) in critically ill patients. This study examined the effects of high- versus low-volume saline administration on AKI after cardiac surgery. Methods:In this retrospective study, we evaluated 1,740 consecutive patients who underwent cardiac surgery over a 2-year period. The patients were divided into high-volume saline (n=328, 18.8%) and low-volume saline (n=1,412, 81.2%) groups based on the amount of saline (>1 or ≤1 L, respectively) administered during the first 48 postoperative hours. Results:AKI, the primary outcome, was defined according to the Risk, Injury, Failure, Loss, End Stage classification. There were no significant differences in the incidence of AKI (P=0.46), new renal replacement therapy (RRT) (P=0.39), and early mortality (P=0.52) between the 2 groups. Adjustment of baseline characteristics using propensity score matching showed that high-volume of saline administration was not significantly associated with an increased risk of AKI (OR, 1.22; 95% CI, 0.77-1.93; P=0.38), new RRT (OR, 1.25; 95% CI, 0.68-2.28; P=0.45), or early mortality (HR, 0.98; 95% CI, 0.48-2.02; P=0.97). These results were validated by further adjustments for significant covariates. Conclusions:High-volume administration of saline in the period following cardiac surgery was not associated with a significant increase in the risk of AKI.
journal_name
J Thorac Disjournal_title
Journal of thoracic diseaseauthors
Lim JY,Kang PJ,Jung SH,Choo SJ,Chung CH,Lee JW,Kim JBdoi
10.21037/jtd.2018.10.113subject
Has Abstractpub_date
2018-12-01 00:00:00pages
6753-6762issue
12eissn
2072-1439issn
2077-6624pii
jtd-10-12-6753journal_volume
10pub_type
杂志文章abstract:Background:Pleural fluid pH and glucose levels are both recommended in the workup of pleural effusions. Whether their levels correlate and predict each other or contribute independent knowledge is unclear. We aimed to investigate the pH/glucose relationship, assess their concordance and ascertain whether performing bot...
journal_title:Journal of thoracic disease
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abstract:Background:Video-assisted thoracoscopic surgery has been identified as priori choice compared with open approaches in esophageal cancer surgery. With the developments in the Da Vinci robotic system, the robot-assisted minimally invasive esophagectomy (RAMIE) has been increasingly popular. However, whether RAMIE could b...
journal_title:Journal of thoracic disease
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journal_title:Journal of thoracic disease
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doi:10.21037/jtd.2018.03.07
更新日期:2018-03-01 00:00:00
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journal_title:Journal of thoracic disease
pub_type: 杂志文章,评审
doi:10.21037/jtd.2019.02.04
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journal_title:Journal of thoracic disease
pub_type: 杂志文章,评审
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journal_title:Journal of thoracic disease
pub_type: 杂志文章
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journal_title:Journal of thoracic disease
pub_type: 杂志文章
doi:10.3978/j.issn.2072-1439.2013.05.03
更新日期:2013-06-01 00:00:00
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journal_title:Journal of thoracic disease
pub_type: 杂志文章
doi:10.3978/j.issn.2072-1439.2016.01.27
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journal_title:Journal of thoracic disease
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journal_title:Journal of thoracic disease
pub_type: 杂志文章
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更新日期:2015-12-01 00:00:00
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journal_title:Journal of thoracic disease
pub_type: 杂志文章
doi:10.21037/jtd.2017.08.07
更新日期:2017-09-01 00:00:00
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journal_title:Journal of thoracic disease
pub_type: 杂志文章
doi:10.21037/jtd.2019.05.22
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journal_title:Journal of thoracic disease
pub_type: 杂志文章,评审
doi:10.21037/jtd.2018.05.106
更新日期:2018-05-01 00:00:00
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journal_title:Journal of thoracic disease
pub_type: 杂志文章
doi:10.3978/j.issn.2072-1439.2015.05.09
更新日期:2015-05-01 00:00:00
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journal_title:Journal of thoracic disease
pub_type: 杂志文章
doi:10.3978/j.issn.2072-1439.2014.11.43
更新日期:2014-12-01 00:00:00
abstract::Esophagectomy is a complex surgical procedure associated with high rates of mortality and morbidity, mainly dominated by pulmonary complications. Minimally invasive approaches have been developed in order to decrease postoperative morbidity, including totally minimally invasive esophagectomy (MIE) and hybrid esophagec...
journal_title:Journal of thoracic disease
pub_type: 杂志文章,评审
doi:10.21037/jtd.2018.12.92
更新日期:2019-04-01 00:00:00
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journal_title:Journal of thoracic disease
pub_type: 杂志文章
doi:10.21037/jtd-19-3310b
更新日期:2020-05-01 00:00:00
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journal_title:Journal of thoracic disease
pub_type: 杂志文章
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journal_title:Journal of thoracic disease
pub_type:
doi:10.21037/jtd.2018.02.08
更新日期:2018-03-01 00:00:00
abstract::The vascular structure related compression of esophagus is rather rare. Aberrant right subclavicular artery accounts for the majority of the rare entity, while the thoracic aorta aneurysm is a more dangerous type, called as dysphagia aortica. Delay in diagnosis and treatment of the dysphagia aortica predisposes to rup...
journal_title:Journal of thoracic disease
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doi:10.3978/j.issn.2072-1439.2013.11.15
更新日期:2013-12-01 00:00:00
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journal_title:Journal of thoracic disease
pub_type: 杂志文章
doi:10.3978/j.issn.2072-1439.2015.12.51
更新日期:2015-12-01 00:00:00
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journal_title:Journal of thoracic disease
pub_type: 杂志文章
doi:10.21037/jtd.2018.08.43
更新日期:2018-09-01 00:00:00
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journal_title:Journal of thoracic disease
pub_type: 杂志文章
doi:10.3978/j.issn.2072-1439.2013.05.22
更新日期:2013-06-01 00:00:00
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journal_title:Journal of thoracic disease
pub_type:
doi:10.3978/j.issn.2072-1439.2014.01.22
更新日期:2014-02-01 00:00:00
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journal_title:Journal of thoracic disease
pub_type: 杂志文章
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更新日期:2016-07-01 00:00:00
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journal_title:Journal of thoracic disease
pub_type: 杂志文章
doi:10.21037/jtd-20-2038
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:Video-assisted thoracic surgery (VATS) emerged as a minimally invasive surgery for diseases in the field of thoracic surgery. We herein reviewed our experience on thoracoscopic lobectomy for early lung cancer and evaluated Health System use. METHODS:A cost-effectiveness study was performed comparing VATS vs...
journal_title:Journal of thoracic disease
pub_type: 杂志文章
doi:10.21037/jtd.2017.07.51
更新日期:2017-08-01 00:00:00