Meta-analysis of efficacy and safety of custirsen in patients with metastatic castration-resistant prostate cancer.

abstract：:Thyroid cancer (TC) is the most common malignancy of the endocrine system. The relationship between iodine intake and TC risk is controversial always. We aim to figure out the relationship between iodine intake and TC using meta-analysis. Literature research in MEDLINE, Embase, China National Knowledge Infrastructure,...

journal_title：Medicine

authors： Cao LZ,Peng XD,Xie JP,Yang FH,Wen HL,Li S

更新日期：2017-05-01 00:00:00

abstract：RATIONALE:Metastasis to the small intestine from a primary lung cancer is rare, and is associated with a poor prognosis. Early diagnosis of small intestine metastasis is difficult because of the low incidence of clinically apparent symptoms. PATIENT CONCERNS:Clinical data and treatment of a 59-year-old man with small ...

journal_title：Medicine

authors： Ying X,Wang M,Verma V,Wang M,Ye S,Bi J,Zhou X,Han G,Zhen W

更新日期：2017-08-01 00:00:00

abstract：RATIONALE:Pathological fracture of the mandible caused by radicular cyst is rare. This report describes a unique case of a mandibular pathological fracture caused by radicular cyst, arising from an endodontically treated molar. PATIENT CONCERN:A 49-year-old female was referred to our department with persistent pain in...

journal_title：Medicine

authors： Xiao X,Dai JW,Li Z,Zhang W

更新日期：2018-12-01 00:00:00

abstract：RATIONALE:The capsular warning syndrome (CWS) is a rare and special type of transient ischemic attacks (TIAs) syndrome. The pathophysiology of CWS is very complicate, and intracranial atherosclerotic stenosis (ICAS) is rare cause. Moreover, the effective and standard therapy has not yet been established. PATIENT CONCE...

journal_title：Medicine

authors： Xu J,Zhuang M,Bao G,Zhai Y,Yang GY,Xue G,Li Q

更新日期：2020-02-01 00:00:00

abstract：:High prevalence of obstructive sleep apnea (OSA) has increased the demands for more convenient and accessible diagnostic devices other than standard in-lab polysomnography (PSG). Despite the increasing utility of photoplethysmograph (PPG), it remains understudied in underserved populations. This study aimed to evaluat...

journal_title：Medicine

authors： Li Y,Gao H,Ma Y

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:The kinesin family (KIF) is reported to be aberrantly expressed and significantly correlated with survival outcomes in patients with various cancers. This meta-analysis was carried out to quantitatively evaluate the prognostic values of partial KIF members in cancer patients. METHODS:Two well-known KIF memb...

journal_title：Medicine

authors： Li X,Shu K,Wang Z,Ding D

更新日期：2019-11-01 00:00:00

abstract：RATIONALE:Carbapenem-resistant Klebsiella pneumonia (CRKP) infections have been a concerning threat, especially in organ transplant patients with very high mortality. Allograft hemorrhage associated with CRKP infection has never been described. PATIENT CONCERNS:A total of 6 recipients tested positive for CRKP were ide...

journal_title：Medicine

authors： Wang Z,Qian Y,Bai H,Yang J,Li X

更新日期：2020-03-01 00:00:00

abstract：:Several studies have pointed out a significant association between rheumatoid arthritis (RA) and accelerated atherosclerosis. At the best of our knowledge, no such study has been carried out in a large Italian series and, in this study, we aimed to investigate the prevalence of both subclinical atherosclerosis and his...

journal_title：Medicine

authors： Ruscitti P,Margiotta DPE,Macaluso F,Iacono D,D'Onofrio F,Emmi G,Atzeni F,Prete M,Perosa F,Sarzi-Puttini P,Emmi L,Cantatore FP,Triolo G,Afeltra A,Giacomelli R,Valentini G

更新日期：2017-10-01 00:00:00

abstract：RATIONALE:Achromobacter xylosoxidans infection is mostly reported in immunocompromised patients. Until now, it is still rarely reported in patients undergoing peritoneal dialysis. PATIENT CONCERNS:This is the 1st case of A xylosoxidans infection due to tunnel infection of a Tenckhoff catheter. DIAGNOSIS:The diagnosis...

journal_title：Medicine

authors： Tsai JL,Tsai SF

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:There is a considerable amount of literature on the potential relationship between human leukocyte antigen-G 14-bp Ins/Del polymorphism and virus infection; however, results from these studies were inconclusive. OBJECTIVES:A meta-analysis was carried out to determine whether the 14-bp Ins/Del polymorphism i...

journal_title：Medicine

authors： Lv H,Lv H,Lin Z,Chen L,Zhu M,Hong D

更新日期：2018-09-01 00:00:00

abstract：:To investigate the efficacy, key technical points, and complication management of the transabdominal preperitoneal (TAPP) approach for incarcerated inguinal hernia repair. Seventy-three patients with incarcerated inguinal hernias underwent TAPP surgery in our department between Jan 2010 and Dec 2015. A retrospective r...

journal_title：Medicine

authors： Yang S,Zhang G,Jin C,Cao J,Zhu Y,Shen Y,Wang M

更新日期：2016-12-01 00:00:00

abstract：:Apolipoprotein E (APOE) gene has been implicated as one of the genes susceptible to temporal lobe epilepsy (TLE), but the association is inconsistent. We carried out a study to investigate the association of APOEε4 allele with a subtype of TLE-nonlesional mesial temporal lobe epilepsy (NLMTLE) in Han Chinese people.T ...

journal_title：Medicine

authors： Li Z,Ding C,Gong X,Wang X,Cui T

更新日期：2016-03-01 00:00:00

abstract：:This study is conducted to investigate the involvement of T-helper (Th) cells and regulatory T cells in epithelial ovarian cancer (EOC).The percentages of Th22, Th17, Th1, and regulatory T cells in the peripheral blood of EOC patients, benign ovarian epithelial neoplasm (BOEN) patients, and healthy control (HC) were e...

journal_title：Medicine

authors： Wang T,Zhang Z,Xing H,Wang L,Zhang G,Yu N,Wang J,Guo W,Jiang J

更新日期：2017-10-01 00:00:00

abstract：:Like research in general internal medicine, family medicine research can play an important role in improving medical knowledge. We aimed to compare articles published in family medicine journals with articles published in general internal medicine journals. In this bibliometric study, we retrieved 658 randomly selecte...

journal_title：Medicine

authors： Sebo P

更新日期：2020-06-12 00:00:00

abstract：BACKGROUND:High-grade prostate cancer (PCa) has a poor prognosis, and up to 15% of patients worldwide experience lymph node invasion (LNI). To further improve the prediction lymph node invasion in prostate cancer, we adopted risk scores of the genes expression based on the nomogram in guidelines. METHODS:We analyzed c...

journal_title：Medicine

authors： Cao HM,Wan Z,Wu Y,Wang HY,Guan C

更新日期：2019-07-01 00:00:00

abstract：:The human epidermal growth factor receptor 2 (HER2) is amplified in approximately 20% of breast cancers, and HER2 receptor targeting therapy is associated with a significant improvement in disease-free and overall survival. In several clinical trials, the pathologic complete response (pCR) rate was significantly incre...

journal_title：Medicine

authors： Choi JH,Jeon CW,Kim YO,Jung S

更新日期：2020-11-13 00:00:00

abstract：BACKGROUND:Acute mountain sickness (AMS) is the effect when people accessing high altitude in a short period of time. As a cyclooxygenase (COX) inhibitor, ibuprofen could alleviate the symptoms of AMS. However, whether it can prevent AMS or not is still controversial. It is necessary to perform a meta-analysis to evalu...

journal_title：Medicine

authors： Yi H,Wang K,Gan X,Li L,Zhang Q,Xiang J,Yuan X,Zhang Y,Wang Y

更新日期：2020-11-13 00:00:00

abstract：:Modifiable cardiovascular risk factors such as obesity, hypertension, dyslipidemia, smoking, diabetes mellitus, and metabolic syndrome can easily give rise to coronary heart disease (CHD). However, due to the existence of the so-called "obesity paradox" and "smoking paradox," the impact of these modifiable cardiovascu...

journal_title：Medicine

authors： Bundhun PK,Wu ZJ,Chen MH

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:The efficacy and safety of oral tranexamic acid (TXA) remain controversial because of the small number of clinical studies. The aim of the present study was to compare the efficacy and safety of oral TXA with intravenous TXA in patients undergoing total hip arthroplasty and total knee arthroplasty in a syste...

journal_title：Medicine

authors： Sun C,Zhang X,Chen L,Deng J,Ma Q,Cai X,Yang H

更新日期：2020-10-30 00:00:00

abstract：:The importance of bedside assistants has been well established in various robotic procedures. However, the effect of assistants on the surgical outcomes of thyroid surgery remains unclear. We investigated the effects of a dedicated robot assistant (DRA) in robotic thyroidectomy. We also evaluated the learning curve of...

journal_title：Medicine

authors： Kwon H

更新日期：2020-09-04 00:00:00

abstract：:The free antiretroviral therapy (ART) program in India has scaled up to register second largest number of people living with HIV/AIDS across the globe. To assess the effectiveness of current first-line regimen we estimated virological suppression on completion of 1 year of ART. The study describes the correlates of vi...

journal_title：Medicine

authors： Karade SK,Ghate MV,Chaturbhuj DN,Kadam DB,Shankar S,Gaikwad N,Gurav S,Joshi R,Sane SS,Kulkarni SS,Kurle SN,Paranjape RS,Rewari BB,Gangakhedkar RR

更新日期：2016-09-01 00:00:00

abstract：:Controversy remains over whether random cervical biopsies and endocervical curettage (ECC) should be used in women with positive screening but negative colposcopy. Our paper aims to determine the indications for random biopsies and ECC among these screened positive women.Three thousand two hundred thirteen women with ...

journal_title：Medicine

authors： Hu SY,Zhang WH,Li SM,Li N,Huang MN,Pan QJ,Zhang X,Han Y,Zhao FH,Chen W,Qiao YL

更新日期：2017-04-01 00:00:00

abstract：RATIONALE:Metastatic involvement of the gastrointestinal tract is an uncommon scenario encountered in the clinical practice. Our case represents a gastric outlet obstruction (GOO) as a consequence of distant Transitional cell carcinoma (TCC) metastasis without any lymph node involvement in association with inflammatory...

journal_title：Medicine

authors： Bandireddy M,Baffy N

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Mandibular overdentures retained by a single implant placed in the midline of edentulous mandible have been reported to be more comfortable and function better than complete dentures. Although single-implant overdentures are still more costly than conventional complete dentures, there are a few studies which...

journal_title：Medicine

authors： Kanazawa M,Tanoue M,Miyayasu A,Takeshita S,Sato D,Asami M,Lam TV,Thu KM,Oda K,Komagamine Y,Minakuchi S,Feine J

更新日期：2018-05-01 00:00:00

abstract：:This study aims to investigate the changes of cytokines and the effect of programmed death ligand 1 (PD-L1) signaling pathway on T cell function in patients with immune thrombocytopenic purpura (ITP).Totally, 40 untreated ITP patients were recruited and 30 healthy people were recruited as the healthy control. Then who...

journal_title：Medicine

authors： Wu D,Liu Y,Pang N,Sun M,Wang X,Haridia Y,Zhao F,Qin Y,Fan W,Guo X,Ding J

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Osteoporosis is a common skeletal disorder in eldest people, especially in postmenopausal women. The osteoprotegerin (OPG) gene has been reported to be associated with the BMD and pathogenesis of osteoporosis. However, the results were inconsistent and inconclusive in previous studies. METHODS:A meta-analys...

journal_title：Medicine

authors： Peng Y,Sheng X,Xue F,Qian Y

更新日期：2018-12-01 00:00:00

abstract：RATIONALE:We report on a patient with mild traumatic brain injury (TBI) by follow-up diffusion tensor tractography (DTT), and observed for approximately nine monthsby serial diffusion tensor tractography (DTT). PATIENT CONCERNS:A 66-year-old male patient was injured in a car crash. Approximately four weeks after the c...

journal_title：Medicine

authors： Jang SH,Kwon HG

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Undiagnosed pleural effusions (UPEs) are a common problem of respiratory medicine, leading to an increased diagnostic burden globally. However, the most efficient and cost-effective approaches to UPEs remain controversial. This study aimed to assess the diagnostic value of ultrasound-guided nee...

journal_title：Medicine

authors： Lin Z,Wu D,Wang J,Wang C,Huang M

更新日期：2020-07-02 00:00:00

abstract：BACKGROUND:Because of aging of population, osteoporotic vertebral compression fracture (OVCF) appears an increasing incidence rate. Conservative therapy (CT) and balloon kyphoplasty (BKP) have been used to treat OVCFs. However, an increase in new vertebral compression fractures at nontreated levels following BKP is of ...

journal_title：Medicine

authors： Li HM,Zhang RJ,Gao H,Jia CY,Zhang JX,Dong FL,Shen CL

更新日期：2018-10-01 00:00:00

abstract：:We evaluated the tumor response and survival according to the KRAS oncogene status in locally advanced rectal cancer. One hundred patients with locally advanced rectal cancer (cT3-4N0-2M0) received preoperative radiation of 50.4 Gy in 28 fractions with 5-fluorouracil and total mesorectal excision. Tumor DNA from each ...

journal_title：Medicine

authors： Lee JW,Lee JH,Shim BY,Kim SH,Chung MJ,Kye BH,Kim HJ,Cho HM,Jang HS

更新日期：2015-08-01 00:00:00