Mitteilungen des BDRh.

abstract：:Cartilage destruction in arthritis and osteoarthritis is linked to aberrant cytokine and growth factor expression in the affected tissues. It becomes clear that the balance of protective and destructive cytokines is more important for the net destruction than the absolute levels of destructive mediators. IL-1 is a key...

journal_title：Zeitschrift fur Rheumatologie

authors： van den Berg WB

更新日期：1999-06-01 00:00:00

abstract：:Arthrosis deformans is a common disease worldwide with a high prevalence among all ethnic groups. All joints may be affected and genetic factors influence the onset of the disease. The main symptoms include pain and increasing immobility over the course of the illness. Treatment in early stages is conservative. In the...

journal_title：Zeitschrift fur Rheumatologie

authors： Rehart S,Lehnert H

更新日期：2008-07-01 00:00:00

abstract：AIM:The present study should elucidate the efficacy, patient acceptability, and side effect profiles of Oxaprozin and Diclofenac retard when given to patients with active primary osteoarthrosis. METHODS:80 outpatients with active primary osteoarthrosis with a radiological grade of II or III in the hip or knee joint (m...

journal_title：Zeitschrift fur Rheumatologie

authors： Karbowski A,Schwitalle M,Eckardt A

更新日期：1998-04-01 00:00:00

abstract：INTRODUCTION:Methotrexate (MTX) is an antineoplastic agent widely used in low dose to treat patients with rheumatoid arthritis (RA). Its side effects can partly be explained by folate antagonism. Folinic acid (Leucovorin) is generally administered with MTX to decrease MTX-induced toxicity. However information regarding...

journal_title：Zeitschrift fur Rheumatologie

authors： Shahin AA,Ismail MM,Saleh AM,Moustafa HA,Aboul-Ella AA,Gabr HM

更新日期：2001-04-01 00:00:00

abstract：:Five to 9 months after a comparative study of 2 groups of patients with coxarthrosis and gonarthrosis, 69 individuals (group 1) receiving Arteparon forte injections and physical therapy and 46 persons (group 2) with physical therapy only, questioneer with specific questions was sent out. From 72 questioneers mailed 55...

journal_title：Zeitschrift fur Rheumatologie

authors： Rau E,Schmid C,Bach GL

更新日期：1977-07-01 00:00:00

abstract：:To study the hormonal perturbations in FMS patients we injected sixteen FMS patients and seventeen controls a cocktail of the hypothalamic releasing hormones: Corticotropin-releasing hormone (CRH), Thyrotropin-releasing hormone (TRH), Growth hormone-releasing hormone (GHRH), and Luteinizing hormone-releasing hormone (...

journal_title：Zeitschrift fur Rheumatologie

authors： Riedel W,Layka H,Neeck G

更新日期：1998-01-01 00:00:00

abstract：:Based on the most recent studies, it clearly appears that long-term hormone replacement therapy (HRT) prevents fractures but does not improve established coronary artery disease. In addition, HRT leads to a small increase in breast cancer incidence and to a decrease in colorectal cancer incidence. HRT increases the in...

journal_title：Zeitschrift fur Rheumatologie

authors： Uebelhart B,Frey D,Uebelhart D

更新日期：2003-12-01 00:00:00

abstract：:Fifty-seven patients with rheumatoid arthritis were examined clinically, radiologically, and by means of transcranial magnetic brain stimulation. With this method central motor conduction times of the corticospinal pathways can be measured. The aim of the study was to compare the different methods to detect a cervical...

journal_title：Zeitschrift fur Rheumatologie

authors： Theiler R,Dvorak J,Janssen B,Baumgartner H,Herdmann J

更新日期：1990-09-01 00:00:00

abstract：INTRODUCTION:Only insufficient data are available regarding the question whether treatment with immunosuppressants or biologicals is feasible and safe in patients with a history of malignancy. METHOD:Literature search via PubMed, EULAR abstracts and ACR abstracts from 2013 to 2015. RESULTS:The Société Francaise de Rh...

journal_title：Zeitschrift fur Rheumatologie

authors： Schmalzing M,Strangfeld A,Tony HP

更新日期：2016-02-01 00:00:00

abstract：:The diagnosis of rheumatoid arthritis has been hampered by the lack of a truly disease-specific serologic marker. Thus, despite its moderate specificity rheumatoid factor (RF) is still the only established marker antibody for RA and among the diagnostic criteria of the American College of Rheumatology the only serolog...

journal_title：Zeitschrift fur Rheumatologie

authors： Steiner G,Smolen JS

更新日期：2002-12-01 00:00:00

abstract：:Cytokine driven inflammation is a common feature in autoimmune diseases. Cytokines are needed under physiological conditions within the innate and adaptive immune systems to control infectious diseases and neoplastic disorders by regulation of the cell cycle and apoptosis. Cytokines can also be found in persistently i...

journal_title：Zeitschrift fur Rheumatologie

authors： Feuchtenberger M,Kneitz C,Tony HP

更新日期：2007-07-01 00:00:00

abstract：:Wegener's granulomatosis, Churg-Strauss syndrome and analgesics intolerance syndrome with polyps demonstrate non-specific manifestations in the head and neck region. These symptoms can often lead to early diagnosis and initiation of the correct therapy. However, symptoms are often ambiguous and many rare differential ...

journal_title：Zeitschrift fur Rheumatologie

authors： Laudien M,Ambrosch P,Till A,Podschun R,Lamprecht P

更新日期：2008-09-01 00:00:00

abstract：:Seronegative rheumatoid arthritis (RA) patients have increased proportions of OKT-4+ (helper) T cells and diminished proportions of OKT-8+ (suppressor/cytotoxic) T cells in the peripheral blood. This phenomenon corresponds to diminished inhibition of B cell activation by peripheral blood lymphocytes (PBL). Seropositiv...

journal_title：Zeitschrift fur Rheumatologie

authors： Lemm G,Warnatz H

更新日期：1984-05-01 00:00:00

abstract：BACKGROUND:Patients with an inflammatory disease have an elevated risk for periprosthetic joint infections due to impairment of the immune system caused by the disease itself in combination with disease-modifying antirheumatic drugs (DMARD). These infections can cause life-threatening sepsis. Unfortunately recommendati...

journal_title：Zeitschrift fur Rheumatologie

authors： Illgner U,Uekötter A,Bause L

更新日期：2014-06-01 00:00:00

abstract：:Many rheumatological diseases are either caused by specific known proteins, such as antibodies or mediated by a plethora of cytokines. Both the unspecific immunosuppressive therapy and the specific action of biologics usually require time to be effective; therefore, extracorporeal forms of treatment are increasingly b...

journal_title：Zeitschrift fur Rheumatologie

authors： Boser M,Kielstein JT

更新日期：2016-12-01 00:00:00

abstract：:Autoreactivity plays a major role in the pathogenesis of RA. The rheumatoid factor has been and still is for now more than 50 years the only autoreactivity that is clinically applied in the diagnosis of RA. This well reflects the current way of thinking that a single antigen or a single cause drives an individual into...

journal_title：Zeitschrift fur Rheumatologie

authors： Bläss S,Engel JM,Burmester GR

更新日期：2001-02-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is associated with a shortened life expectancy. Most premature deaths are caused by cardiovascular (CV) events; therefore it is of importance to consider the increased CV risk when treating RA patients. Traditional CV risk factors cannot fully explain the increased risk but the common underst...

journal_title：Zeitschrift fur Rheumatologie

authors： Pieringer H,Hoppe UC

更新日期：2013-05-01 00:00:00

abstract：:Bone morphogenetic proteins (BMPs) belong to the transforming growth factor-beta superfamily. Their potential for organ and tissue regeneration and repair has been intensively investigated in recent years. Studies on fetal development have demonstrated the important role of these proteins for the development and diffe...

journal_title：Zeitschrift fur Rheumatologie

authors： Bramlage CP,Häupl T,Kaps C,Bramlage P,Müller GA,Strutz F

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:The goal of the present study was to investigate the osteogenic potential of ligament fibroblasts from patients with ankylosing spondylitis (AS). MATERIALS AND METHODS:Ligament fibroblasts were isolated from tissues harvested from AS patients and patients with aseptic necrosis of the femoral head (ANFH) who...

journal_title：Zeitschrift fur Rheumatologie

authors： Yang M,Yuan H,Miao M,Xu W

更新日期：2015-05-01 00:00:00

abstract：:Assessment of disease consequences (outcome) requires reliable, valid, and sensitive instruments. Psychometrically sound generic health-status instruments such as the SF-36 have been validated for many languages and are available in German. Instead, most disease specific instruments have been developed in English and ...

journal_title：Zeitschrift fur Rheumatologie

authors： Stucki G,Stucki S,Sangha O

更新日期：1997-10-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is a chronic inflammatory disease, which is mainly characterized by synovial hyperplasia, pathological immune phenomena and progressive destruction of the affected joints. Various cell types are involved in the pathogenesis of RA including T cells, antigen presenting cells, and endothelial ce...

journal_title：Zeitschrift fur Rheumatologie

authors： Seemayer CA,Distler O,Kuchen S,Müller-Ladner U,Michel BA,Neidhart M,Gay RE,Gay S

更新日期：2001-10-01 00:00:00

abstract：:Progressive multifocal leukoencephalopathy (PML) is a rare but often fatal demyelinating disease of the central nervous system induced by the JC virus. It mainly occurs in immunocompromised patients. Growing interest in rheumatology has arisen from reports of patients with rheumatic diseases suffering from PML. A dire...

journal_title：Zeitschrift fur Rheumatologie

authors： Kneitz C,Wiendl H

更新日期：2008-07-01 00:00:00

abstract：:Eight human femoral heads, surgically removed from patients with the clinical diagnosis: coxarthrosis or necrosis, were examined. In six of these we found severe arthrosis combined with synovitis and pannus formation. The pannus appeared as granulation tissue or fibrous connective tissue covering the surface of the ca...

journal_title：Zeitschrift fur Rheumatologie

authors： Pataki A,Lothe K,Spycher MA,Rüttner JR,Cserhati MD

更新日期：1983-11-01 00:00:00

abstract：:Biochemical studies of rats with mycoplasma arthritis revealed new findings in pathogenesis and pathophysiology. Preliminary examinations showed that mycoplasmas release specific endonucleases and exonucleases. In evaluating the isoenzymes of the lactate dehydrogenases, malate dehydrogenases as well as of the esterase...

journal_title：Zeitschrift fur Rheumatologie

authors： Klein G

更新日期：1975-05-01 00:00:00

abstract：UNLABELLED:Influence of anti-rheumatic drugs on human lymphocytes, especially T and B cell membranes, was studies with D-penicillamine, aurothiomalate, dexamethasone, cyclophosphamide, mitomycin C and aspirin. METHOD:Peripheral blood obtained from five healthy individuals and lymphocytes were separated by centrifugati...

journal_title：Zeitschrift fur Rheumatologie

authors： Yoshino S,Ishiyama I

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND:Early detection of patients with axial spondylarthritis (axSpA) in primary care is difficult. The combination of various parameters indicative of inflammatory back pain (AWARE criteria) was found to be beneficial in an initial study. OBJECTIVE:Review of the criteria for the identification of young patients ...

journal_title：Zeitschrift fur Rheumatologie

authors： Braun J,Mosch T,Fischer I,Kiltz U

更新日期：2019-08-01 00:00:00

abstract：:The neonatal lupus erythematosus syndrome, first described by McCuistion and Schoch in 1954, is associated with characteristic skin lesions and congenital heart block in the new-born, and the presence of Ro-(SSA), La-(SSB), or RNP antibodies in mothers and infants. A transplacental transference of maternal autoantibod...

journal_title：Zeitschrift fur Rheumatologie

authors： Mayet WJ,Hermann E,Bachmann M,Poralla T,Meyer zum Büschenfelde KH

更新日期：1989-03-01 00:00:00

abstract：:Systemic sclerosis (SSc) is a polymorphic and heterogenic systemic disorder with inflammation, fibrosis and vascular damage. Early diagnosis and classification may be difficult if disease expression is oligosymptomatic (undifferentiated), presenting with only Raynaud's phenomenon or limited scleroderma. Scleroderma sp...

journal_title：Zeitschrift fur Rheumatologie

authors： Genth E,Krieg T

更新日期：2006-07-01 00:00:00

abstract：:We investigated the relationships between prolactin (PRL) levels and antibody occurrence in systemic lupus erythematosus (SLE). No significant association between PRL levels and the majority of the autoantibodies studied (anti-U1 RNP, anti-rRNP, anti-Sm, anti-dsDNA, anti-DNP, auto-LCA, anti-EACA) could be confirmed (P...

journal_title：Zeitschrift fur Rheumatologie

authors： Kozáková D,Rovenský J,Cebecauer L,Bosák V,Jahnová E,Vigas M

更新日期：2000-01-01 00:00:00

abstract：:After approval of TNF and interleukin-1 inhibiting agents for treatment of refractory rheumathoid arthritis, new agents inhibiting interleukin-6 and costimulatory pathways are entering clinical phase I and II trials. Blockade of costimulation by using a CTLA4 immunoglobulin fusion protein (CTLA4Ig), which inhibits the...

journal_title：Zeitschrift fur Rheumatologie

authors： Perniok A,Rubbert-Roth A

更新日期：2003-10-01 00:00:00