U-Th dated speleothem recorded geomagnetic excursions in the Lower Brunhes.

abstract：:Tick-borne diseases are the most common vector-borne diseases in the United States, with serology being the primary method of diagnosis. We developed the first multiplex, array-based assay for serodiagnosis of tick-borne diseases called the TBD-Serochip. The TBD-Serochip was designed to discriminate antibody responses...

journal_title：Scientific reports

authors： Tokarz R,Mishra N,Tagliafierro T,Sameroff S,Caciula A,Chauhan L,Patel J,Sullivan E,Gucwa A,Fallon B,Golightly M,Molins C,Schriefer M,Marques A,Briese T,Lipkin WI

更新日期：2018-02-16 00:00:00

abstract：:Colon cancer stem cells have been attributed to poor prognosis, therapeutic resistance and aggressive nature of the malignancy. Recent reports associated CD44v6 expression with relapse, metastasis and reduced 5-year survival of colon cancer patients, thereby making it a potential therapeutic target. Thus, in this stud...

journal_title：Scientific reports

authors： Patel S,Waghela B,Shah K,Vaidya F,Mirza S,Patel S,Pathak C,Rawal R

更新日期：2018-11-19 00:00:00

abstract：:An abrupt onset of the new tongue-shaped deformation of magnetic surface in magnetized plasmas, which was conjectured in since the 1960s but has not been observed, is experimentally identified just before an abrupt onset of a large-scale collapse event. Two novel properties of the event are identified. First, the tran...

journal_title：Scientific reports

authors： Ida K,Kobayashi T,Itoh K,Yoshinuma M,Tokuzawa T,Akiyama T,Moon C,Tsuchiya H,Inagaki S,Itoh SI

更新日期：2016-10-31 00:00:00

abstract：:Monitoring one's actions is essential for goal-directed performance. In the event-related potential (ERP), errors are followed by fronto-centrally distributed negativities. These error(-related) negativity (Ne/ERN) amplitudes are often found to be attenuated in patients with Parkinson's disease (PD) compared to health...

journal_title：Scientific reports

authors： Seer C,Lange F,Loens S,Wegner F,Schrader C,Dressler D,Dengler R,Kopp B

更新日期：2017-01-24 00:00:00

abstract：:Prostate-specific antigen (PSA) kinetics predicts survival in castration-resistant prostate cancer (CRPC); however, the influence of prior treatment on this relationship is unclear. Patients with CRPC were stratified according to time to PSA nadir and time to CRPC progression to investigate their prognostic significan...

journal_title：Scientific reports

authors： Hah YS,Lee JS,Rha KH,Hong SJ,Chung BH,Koo KC

更新日期：2019-08-15 00:00:00

abstract：:Growth factors have great therapeutic potential for various disease therapy and tissue engineering applications. However, their clinical efficacy is hampered by low bioavailability, rapid degradation in vivo and non-specific biodistribution. Nanoparticle based delivery systems are being evaluated to overcome these lim...

journal_title：Scientific reports

authors： Choi WI,Sahu A,Vilos C,Kamaly N,Jo SM,Lee JH,Tae G

更新日期：2017-10-30 00:00:00

abstract：:Teleportation plays an important role in the communication of quantum information between the nodes of a quantum network and is viewed as an essential ingredient for long-distance Quantum Cryptography. We describe a method to teleport the quantum information carried by a photon in a superposition of a number d of ligh...

journal_title：Scientific reports

authors： Goyal SK,Konrad T

更新日期：2013-12-19 00:00:00

abstract：:Sea surface temperature (SST) is a fundamental driver of tropical weather systems such as monsoon rainfall and tropical cyclones. However, understanding of the factors that control SST variability is lacking, especially during the monsoons when in situ observations are sparse. Here we use a ground-breaking observation...

journal_title：Scientific reports

authors： Vijith V,Vinayachandran PN,Webber BGM,Matthews AJ,George JV,Kannaujia VK,Lotliker AA,Amol P

更新日期：2020-04-27 00:00:00

abstract：:Do scientists follow hot topics in their scientific investigations? In this paper, by performing analysis to papers published in the American Physical Society (APS) Physical Review journals, it is found that papers are more likely to be attracted by hot fields, where the hotness of a field is measured by the number of...

journal_title：Scientific reports

authors： Wei T,Li M,Wu C,Yan XY,Fan Y,Di Z,Wu J

更新日期：2013-01-01 00:00:00

abstract：:Novel pain killers without adverse effects are urgently needed. Opioids induce central and intestinal side effects such as respiratory depression, sedation, addiction, and constipation. We have recently shown that a newly designed agonist with a reduced acid dissociation constant (pKa) abolished pain by selectively ac...

journal_title：Scientific reports

authors： Spahn V,Del Vecchio G,Rodriguez-Gaztelumendi A,Temp J,Labuz D,Kloner M,Reidelbach M,Machelska H,Weber M,Stein C

更新日期：2018-06-12 00:00:00

abstract：:The therapeutic value of FK228 as a cancer treatment option is well known, and various types of cancer have been shown to respond to this drug. However, the complete mechanism of FK228 and the affect it has on histone lysine acetylation and the colon cancer cell proteome are largely unknown. In the present study, we u...

journal_title：Scientific reports

authors： Wang TY,Jia YL,Zhang X,Sun QL,Li YC,Zhang JH,Zhao CP,Wang XY,Wang L

更新日期：2015-12-17 00:00:00

abstract：:Sexual dimorphisms are recognized in cardiovascular conditions such as hypertension, stroke, thrombosis and vasculitis. B-type natriuretic peptide (BNP) is a guanylyl cyclase A (GC-A) agonist. The anti-hypertensive, vasodilatory, anti-fibrotic, and anti-hypertrophic properties of BNP are well established in male anima...

journal_title：Scientific reports

authors： Holditch SJ,Schreiber CA,Burnett JC,Ikeda Y

更新日期：2016-05-10 00:00:00

abstract：:Rubber-filler composites are a key component in the manufacture of tyres. The filler provides mechanical reinforcement and additional wear resistance to the rubber, but it in turn introduces non-linear mechanical behaviour to the material which most likely arises from interactions between the filler particles, mediate...

journal_title：Scientific reports

authors： Staniewicz L,Vaudey T,Degrandcourt C,Couty M,Gaboriaud F,Midgley P

更新日期：2014-12-09 00:00:00

abstract：:Many human introns carry out a function, in the sense that they are critical to maintain normal cellular activity. Their identification is fundamental to understanding cellular processes and disease. However, being noncoding elements, such functional introns are poorly predicted based on traditional approaches of sequ...

journal_title：Scientific reports

authors： Chorev M,Joseph Bekker A,Goldberger J,Carmel L

更新日期：2017-06-23 00:00:00

abstract：:Although rare in the U.S., outbreaks due to Neisseria meningitidis do occur. Rapid, early outbreak detection is important for timely public health response. In this study, we characterized U.S. meningococcal isolates (N = 201) from 15 epidemiologically defined outbreaks (2009-2015) along with temporally and geographic...

journal_title：Scientific reports

authors： Whaley MJ,Joseph SJ,Retchless AC,Kretz CB,Blain A,Hu F,Chang HY,Mbaeyi SA,MacNeil JR,Read TD,Wang X

更新日期：2018-10-25 00:00:00

abstract：:Nisin inhibits bacterial growth by generating pores in cell membrane and interrupting cell-wall biosynthesis through specific lipid II interaction. However, the role of the hinge region and C-terminus residues of the peptide in antibacterial action of nisin is largely unknown. Here, using molecular dynamics simulation...

journal_title：Scientific reports

authors： Prince A,Sandhu P,Ror P,Dash E,Sharma S,Arakha M,Jha S,Akhter Y,Saleem M

更新日期：2016-11-29 00:00:00

abstract：:Within the last fifteen years, network theory has been successfully applied both to natural sciences and to socioeconomic disciplines. In particular, bipartite networks have been recognized to provide a particularly insightful representation of many systems, ranging from mutualistic networks in ecology to trade networ...

journal_title：Scientific reports

authors： Saracco F,Di Clemente R,Gabrielli A,Squartini T

更新日期：2015-06-01 00:00:00

abstract：:We describe how an ensemble of four-level atoms in the diamond-type configuration can be applied to create a fully controllable effective coupling between two cavity modes. The diamond-type configuration allows one to use a bimodal cavity that supports modes of different frequencies or different circular polarisations...

journal_title：Scientific reports

authors： Chimczak G,Bartkiewicz K,Ficek Z,Tanaś R

更新日期：2018-10-03 00:00:00

abstract：:The renin-angiotensin system (RAS) plays a key role in the control of vasoconstriction as well as sodium and fluid retention mediated mainly by angiotensin (Ang) II acting at the AT1 receptor (AT1R). Ang-(1-7) is another RAS peptide, identified as the endogenous ligand of the Mas receptor and known to counterbalance m...

journal_title：Scientific reports

authors： Teixeira LB,Parreiras-E-Silva LT,Bruder-Nascimento T,Duarte DA,Simões SC,Costa RM,Rodríguez DY,Ferreira PAB,Silva CAA,Abrao EP,Oliveira EB,Bouvier M,Tostes RC,Costa-Neto CM

更新日期：2017-09-19 00:00:00

abstract：:Pigeon pea is an important legume infested by a plethora of insect pests amongst which gram pod borer Helicoverpa armigera is very prominent. Imparting resistance to this insect herbivore is of global importance in attaining food security. Expression of insecticidal crystal proteins (ICP) in diverse crops has led to i...

journal_title：Scientific reports

authors： Singh S,Kumar NR,Maniraj R,Lakshmikanth R,Rao KYS,Muralimohan N,Arulprakash T,Karthik K,Shashibhushan NB,Vinutha T,Pattanayak D,Dash PK,Kumar PA,Sreevathsa R

更新日期：2018-06-11 00:00:00

abstract：:Basidiomycetes can bioaccumulate high iron contents, but there are few studies on iron availability from the mycelial biomass in order to support their use as an iron-enriched fungal food. This study aimed to evaluate the in vitro iron bioaccumulation and availability in the mycelial biomass of edible and medicinal ba...

journal_title：Scientific reports

authors： Scheid SS,Faria MGI,Velasquez LG,do Valle JS,Gonçalves AC Jr,Dragunski DC,Colauto NB,Linde GA

更新日期：2020-07-30 00:00:00

abstract：:Induced pluripotent stem cells (iPSCs) are promising candidate cells for cardiomyogenesis in the failing heart. However, teratoma/tumour formation originating from undifferentiated iPSCs contaminating the graft is a critical concern for clinical application. Here, we hypothesized that brentuximab vedotin, which target...

journal_title：Scientific reports

authors： Sougawa N,Miyagawa S,Fukushima S,Kawamura A,Yokoyama J,Ito E,Harada A,Okimoto K,Mochizuki-Oda N,Saito A,Sawa Y

更新日期：2018-02-27 00:00:00

abstract：:Vocal expression of emotions has been suggested to be conserved throughout evolution. However, since vocal indicators of emotions have never been compared between closely related species using similar methods, it remains unclear whether this is the case. Here, we investigated vocal indicators of emotional valence (neg...

journal_title：Scientific reports

authors： Maigrot AL,Hillmann E,Anne C,Briefer EF

更新日期：2017-08-18 00:00:00

abstract：:Reduced near-infrared reflectance observed in September 1973 in Skylab images of the western flank of Mt. Etna has been interpreted as an eruption precursor of the January 1974 eruption. Until now, it has been unclear when this signal started, whether it was sustained and which process(es) could have caused it. By ana...

journal_title：Scientific reports

authors： Seiler R,Houlié N,Cherubini P

更新日期：2017-03-07 00:00:00

abstract：:Transplantation of human bone marrow mesenchymal stromal cells (hBM-MSC) promotes functional recovery after stroke in animal models, but the mechanisms underlying these effects remain incompletely understood. We tested the efficacy of Good Manufacturing Practices (GMP) compliant hBM-MSC, injected intravenously 3.5 hou...

journal_title：Scientific reports

authors： Sammali E,Alia C,Vegliante G,Colombo V,Giordano N,Pischiutta F,Boncoraglio GB,Barilani M,Lazzari L,Caleo M,De Simoni MG,Gaipa G,Citerio G,Zanier ER

更新日期：2017-07-31 00:00:00

abstract：:Activation of different slip systems in hexagonal close packed (h.c.p.) metals depends primarily on the c/a ratio, which is an intrinsic property that can be altered through alloying addition. In conventional h.c.p. alloys where there is no diffusion-less phase transformation and associated transformation volume chang...

journal_title：Scientific reports

authors： Sinha S,Nene SS,Frank M,Liu K,Agrawal P,Mishra RS

更新日期：2019-09-12 00:00:00

abstract：:Biofertilizer production and application for sustainable agriculture is already a reality. The methods for biofertilizers delivery in crop fields are diverse. Although foliar spray is gaining wide acceptance, little is known about the influence that the biochemical features of leaves have on the microbial colonization...

journal_title：Scientific reports

authors： Ramírez-Ordorica A,Valencia-Cantero E,Flores-Cortez I,Carrillo-Rayas MT,Elizarraraz-Anaya MIC,Montero-Vargas J,Winkler R,Macías-Rodríguez L

更新日期：2020-05-21 00:00:00

abstract：:Radiotherapy can result in lung diseases pneumonitis or fibrosis dependent on patient susceptibility. Herein we used inbred and genetically altered mice to investigate whether the tissue adaptive immune response to radiation injury influences the development of radiation-induced lung disease. Six inbred mouse strains ...

journal_title：Scientific reports

authors： Paun A,Bergeron ME,Haston CK

更新日期：2017-09-14 00:00:00

abstract：:SUMO belongs to the ubiquitin-like family (UbL) of protein modifiers. SUMO is conserved among eukaryotes and is essential for the regulation of processes such as DNA damage repair, transcription, DNA replication and mitosis. UbL modification of proteins occurs via a specific enzymatic cascade formed by the crosstalk b...

journal_title：Scientific reports

authors： Liu B,Lois LM,Reverter D

更新日期：2017-02-06 00:00:00

abstract：:The pine wood nematode, Bursaphelenchus xylophilus, is the causal agent of pine wilt disease that has devastated pine forests in Asia. Parasitic nematodes are known to have evolved antioxidant stress responses that defend against host plant defenses. In this study, the infestation of whitebark pine, Pinus bungean, wit...

journal_title：Scientific reports

authors： Li Z,Zhang Q,Zhou X

更新日期：2016-06-07 00:00:00