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NATURE文献大全abstract::The interplay between magnetic fields and interacting particles can lead to exotic phases of matter that exhibit topological order and high degrees of spatial entanglement. Although these phases were discovered in a solid-state setting, recent innovations in systems of ultracold neutral atoms-uncharged atoms that do n...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature22811
更新日期:2017-06-21 00:00:00
abstract::Eukaryotic cells contain genes termed proto-oncogenes (c-onc) which have the potential to transform cells in culture and induce tumours in vivo. Most of these genes have been identified by their occasional incorporation into retroviral genomes which can act as natural transducing vectors for these and perhaps other ce...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/309085a0
更新日期:1984-05-03 00:00:00
abstract::In the few species of birds in which males form display partnerships to attract females, one male secures most or all of the copulations. This leads to the question of why subordinate males help in the absence of observable reproductive benefits. Hamilton's concept of kin selection, whereby individuals can benefit ind...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature03325
更新日期:2005-03-03 00:00:00
abstract::Vitamin A is required for normal growth and development, and retinoic acid (RA) may be the active metabolite in this process. Recent evidence indicates that RA acts through binding to a nuclear receptor which belongs to the steroid/thyroid hormone receptor superfamily. The receptors seem to associate with hormone-resp...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/339231a0
更新日期:1989-05-18 00:00:00
abstract::The microtubule cytoskeleton is essential to cell morphogenesis. Growing microtubule plus ends have emerged as dynamic regulatory sites in which specialized proteins, called plus-end-binding proteins (+TIPs), bind and regulate the proper functioning of microtubules. However, the molecular mechanism of plus-end associa...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature06386
更新日期:2007-12-13 00:00:00
abstract::Modifications of histone proteins have essential roles in normal development and human disease. Recognition of modified histones by 'reader' proteins is a key mechanism that mediates the function of histone modifications, but how the dysregulation of these readers might contribute to disease remains poorly understood....
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/s41586-019-1842-7
更新日期:2020-01-01 00:00:00
abstract::Neuroectoderm cells in the cortical ventricular zone generate many diverse cell types, maintain the ventricular zone during embryonic life and create another germinal layer, the subventricular zone, which persists into adulthood. In other vertebrate tissues, including skin, intestine, blood and neural crest, stem cell...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/372263a0
更新日期:1994-11-17 00:00:00
abstract::Molluscs (snails, octopuses, clams and their relatives) have a great disparity of body plans and, among the animals, only arthropods surpass them in species number. This diversity has made Mollusca one of the best-studied groups of animals, yet their evolutionary relationships remain poorly resolved. Open questions ha...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature10526
更新日期:2011-10-26 00:00:00
abstract::Large parts of the Antarctic ice sheet lying on bedrock below sea level may be vulnerable to marine-ice-sheet instability (MISI), a self-sustaining retreat of the grounding line triggered by oceanic or atmospheric changes. There is growing evidence that MISI may be underway throughout the Amundsen Sea embayment (ASE),...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature16147
更新日期:2015-12-03 00:00:00
abstract::The Gakkel ridge, which extends under the Arctic ice cap for approximately 1,800 km, is the slowest spreading ocean ridge on Earth. Its spreading created the Eurasian basin, which is isolated from the rest of the oceanic mantle by North America, Eurasia and the Lomonosov ridge. The Gakkel ridge thus provides unique op...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature06919
更新日期:2008-05-01 00:00:00
abstract::Cysticercosis caused by larval tapeworms is a major public health problem and a cause of substantial economic losses in the farm-animal industries. Taenia ovis in sheep is a particularly important example. Immunity to reinfection with the larvae has a central role in regulating natural transmission of the parasites, a...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/338585a0
更新日期:1989-04-13 00:00:00
abstract::Inhibition of the TOR signalling pathway by genetic or pharmacological intervention extends lifespan in invertebrates, including yeast, nematodes and fruitflies; however, whether inhibition of mTOR signalling can extend lifespan in a mammalian species was unknown. Here we report that rapamycin, an inhibitor of the mTO...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature08221
更新日期:2009-07-16 00:00:00
abstract::The species diversity of natural communities is often strongly related to their productivity. The pattern of this relationship seems to vary: diversity is known to increase monotonically with productivity, to decrease monotonically with productivity, and to be unimodally related to productivity, with maximum diversity...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/35020060
更新日期:2000-08-03 00:00:00
abstract::The interrelationships between major living vertebrate, and even chordate, groups are now reasonably well resolved thanks to a large amount of generally congruent data derived from molecular sequences, anatomy and physiology. But fossils provide unexpected combinations of characters that help us to understand how the ...
journal_title:Nature
pub_type: 杂志文章,评审
doi:10.1038/nature14437
更新日期:2015-04-23 00:00:00
abstract::Estimates of the total number of bacterial species indicate that existing DNA sequence databases carry only a tiny fraction of the total amount of DNA sequence space represented by this division of life. Indeed, environmental DNA samples have been shown to encode many previously unknown classes of proteins and RNAs. B...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature08586
更新日期:2009-12-03 00:00:00
abstract::All of the DNA synthesis genes of budding yeast examined so far are periodically expressed and hence under cell-cycle control (Table 1). Expression occurs near the G1/S phase boundary and the genes seem to be coordinately regulated (reviewed in ref. 4). The upstream promoter sequences of these genes have only a hexame...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/350247a0
更新日期:1991-03-21 00:00:00
abstract::The amount of energy used to run a mile is nearly the same whether it is run at top speed or at a leisurely pace (although it is used more rapidly at the higher speed). This puzzling independence of energy cost and speed is found generally among running animals, although, on a per gram basis, cost is much higher for s...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/346265a0
更新日期:1990-07-19 00:00:00
abstract::An observer moving forwards through the environment experiences a radial pattern of image motion on each retina. Such patterns of optic flow are a potential source of information about the observer's rate of progress, direction of heading and time to reach objects that lie ahead. As the viewing distance changes there ...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/37359
更新日期:1997-12-04 00:00:00
abstract::We have investigated age-related reactivation of the X chromosome by devising a model in which reactivation of a single gene in one cell among many can be identified. We have used mice with an X-autosomal translocation giving consistent non-random inactivation of the normal X (as judged by biochemical and cytogenetic ...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/327725a0
更新日期:1987-06-25 00:00:00
abstract::Megakaryocytopoiesis is the cellular developmental process that leads to platelet production. At least two humoral growth factors may be necessary for megakaryocyte proliferation and maturation. One is a megakaryocyte-colony stimulating factor (MK-CSF) which induces the proliferation and differentiation of megakaryocy...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/369571a0
更新日期:1994-06-16 00:00:00
abstract::Long-term depletion of the stratospheric ozone layer contributes to an increase in terrestrial solar ultraviolet-B radiation. This has deleterious effects on living organisms, such as DNA damage. When exposed to elevated ultraviolet-B radiation (UV-B; 280-315 nm), plants display a wide variety of physiological and mor...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/35017595
更新日期:2000-07-06 00:00:00
abstract::There is an urgent need for new drugs to treat malaria, with broad therapeutic potential and novel modes of action, to widen the scope of treatment and to overcome emerging drug resistance. Here we describe the discovery of DDD107498, a compound with a potent and novel spectrum of antimalarial activity against multipl...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature14451
更新日期:2015-06-18 00:00:00
abstract::The central nervous system has extraordinary plasticity in early life. This is thought to involve N-methyl-D-aspartate (NMDA) receptors which, along with the non-NMDA receptors, mediate fast excitatory synaptic transmission. Although NMDA receptors may be transiently enhanced early in life, it has not been possible to...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/357686a0
更新日期:1992-06-25 00:00:00
abstract::Macrophages are pivotal constituents of the innate immune system, vital for recognition and elimination of microbial pathogens. Macrophages use Toll-like receptors (TLRs) to detect pathogen-associated molecular patterns--including bacterial cell wall components, such as lipopolysaccharide or lipoteichoic acid, and vir...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature02405
更新日期:2004-03-18 00:00:00
abstract::Acetylcholine and dopamine are key neurotransmitters in the extrapyramidal motor system, where they are thought to lie in a 'functional balance' brought about by interactions between the terminals of the dopamine-containing nigrostriatal tract and the cholinergic interneurones of the striatum. The precise nature of th...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/323625a0
更新日期:1986-10-16 00:00:00
abstract::Nuclear-architecture defects have been shown to correlate with the manifestation of a number of human diseases as well as ageing. It is therefore plausible that diseases whose manifestations correlate with ageing might be connected to the appearance of nuclear aberrations over time. We decided to evaluate nuclear orga...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature11557
更新日期:2012-11-22 00:00:00
abstract::For parallel computers to simulate our brains, we must face the fact that human beings have a better claim on the title Homo seriatim than Homo sapiens--we're more consistently serial than wise. ...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/330033a0
更新日期:1987-11-05 00:00:00
abstract::Diatoms are one of the most ecologically successful classes of photosynthetic marine eukaryotes in the contemporary oceans. Over the past 30 million years, they have helped to moderate Earth's climate by absorbing carbon dioxide from the atmosphere, sequestering it via the biological carbon pump and ultimately burying...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature14599
更新日期:2015-08-20 00:00:00
abstract::Recent work demonstrates that stochastic fluctuations in molecular populations have consequences for gene regulation. Previous experiments focused on noise sources or noise propagation through gene networks by measuring noise magnitudes. However, in theoretical analysis, we showed that noise frequency content is deter...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature04194
更新日期:2006-02-02 00:00:00
abstract::The reversal or displacement of the retinal image by prism spectacles leads to extreme disruption of visually guided behaviour, but after an extended period of visual transformation normal behaviour is gradually restored. It is unclear whether this adaptation involves a change in visual perception, the learning of new...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/380523a0
更新日期:1996-04-11 00:00:00