Abstract：
:Wheat and barley are the most highly produced and consumed grains in the world. Various pathogens-viruses, bacteria, fungi, insect pests, and nematode parasites-are major threats to yield and economic losses. Strategies for the management of disease control mainly depend on resistance or tolerance breeding, chemical control, and biological control. The discoveries of RNA silencing mechanisms provide a transgenic approach for disease management. Host-induced gene silencing (HIGS) employing RNA silencing mechanisms and, specifically, silencing the targets of invading pathogens, has been successfully applied in crop disease prevention. Here, we cover recent studies that indicate that HIGS is a valuable tool to protect wheat and barley from diseases in an environmentally friendly way.
journal_name
Int J Mol Scijournal_title
International journal of molecular sciencesauthors
Qi T,Guo J,Peng H,Liu P,Kang Z,Guo Jdoi
10.3390/ijms20010206subject
Has Abstractpub_date
2019-01-08 00:00:00issue
1issn
1422-0067pii
ijms20010206journal_volume
20pub_type
杂志文章,评审abstract：:In vitro chondrogenically differentiated mesenchymal stem cells (MSCs) have a tendency to undergo hypertrophy, mirroring the fate of transient "chondrocytes" in the growth plate. As hypertrophy would result in ossification, this fact limits their use in cartilage tissue engineering applications. During limb developmen...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
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更新日期：2020-02-20 00:00:00
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journal_title：International journal of molecular sciences
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abstract：:Over the last three decades, protein engineering has established itself as an important tool for the development of enzymes and (therapeutic) proteins with improved characteristics. New mutagenesis techniques and computational design tools have greatly aided in the advancement of protein engineering. Yet, one of the p...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
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journal_title：International journal of molecular sciences
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doi：10.3390/ijms21051878
更新日期：2020-03-09 00:00:00
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journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms19020383
更新日期：2018-01-27 00:00:00
abstract：:The plant hormone auxin plays pivotal roles in many aspects of plant growth and development. The auxin/indole-3-acetic acid (Aux/IAA) gene family encodes short-lived nuclear proteins acting on auxin perception and signaling, but the evolutionary history of this gene family remains to be elucidated. In this study, the ...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms18102107
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journal_title：International journal of molecular sciences
pub_type： 社论
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journal_title：International journal of molecular sciences
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更新日期：2020-06-04 00:00:00
abstract：:Tumours are not merely masses of abnormally proliferating cancer cells[...]. ...
journal_title：International journal of molecular sciences
pub_type： 社论
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更新日期：2018-03-14 00:00:00
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journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21072614
更新日期：2020-04-09 00:00:00
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journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21144826
更新日期：2020-07-08 00:00:00
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journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21176363
更新日期：2020-09-02 00:00:00
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journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms19071832
更新日期：2018-06-21 00:00:00
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journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms22020576
更新日期：2021-01-08 00:00:00
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journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21165743
更新日期：2020-08-11 00:00:00
abstract：:Astrocyte proliferation and migration toward injured Central Nervous System (CNS) areas are key features of astrogliosis and glial scar formation. Even though it is known that intracellular and environmental Reactive Oxygen and Nitrogen Species (RONS) affect astrocyte behaviour in physiological and pathophysiological ...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21093343
更新日期：2020-05-08 00:00:00
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journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms19071883
更新日期：2018-06-26 00:00:00
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journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21114179
更新日期：2020-06-11 00:00:00
abstract：:Non-coding RNAs are dominant in the genomic output of the higher organisms being not simply occasional transcripts with idiosyncratic functions, but constituting an extensive regulatory network. Among all the species of non-coding RNAs, small non-coding RNAs (miRNAs, siRNAs and piRNAs) have been shown to be in the cor...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms130810268
更新日期：2012-01-01 00:00:00
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journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms19020640
更新日期：2018-02-24 00:00:00
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journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
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更新日期：2019-06-13 00:00:00
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journal_title：International journal of molecular sciences
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journal_title：International journal of molecular sciences
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doi：10.3390/ijms20082013
更新日期：2019-04-24 00:00:00
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journal_title：International journal of molecular sciences
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doi：10.3390/ijms160921410
更新日期：2015-09-07 00:00:00
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journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
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更新日期：2016-02-06 00:00:00
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journal_title：International journal of molecular sciences
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更新日期：2015-07-10 00:00:00
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journal_title：International journal of molecular sciences
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更新日期：2019-07-30 00:00:00
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journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms18051037
更新日期：2017-05-12 00:00:00
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journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21093078
更新日期：2020-04-27 00:00:00
abstract：:In response to extracellular stimuli, the Raf/MEK/extracellular signal-regulated kinase (ERK) pathway regulates diverse cellular processes. While mainly known as a mitogenic signaling pathway, the Raf/MEK/ERK pathway can mediate not only cell proliferation and survival but also cell cycle arrest and death in different...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms21155436
更新日期：2020-07-30 00:00:00
