Abstract:
BACKGROUND:Vitamin D supplements may prevent recurrence, prolong survival, and improve mood for women with breast cancer, although evidence for these effects is preliminary. METHODS:This report describes vitamin D supplement use by 553 breast cancer patient/survivors (193 who used a naturopathic oncology [NO] provider and 360 who did not) participating in a matched cohort study of breast cancer outcomes. RESULTS:We found that more than half of breast cancer patients reported using vitamin D supplements. Women who received care from NO providers in early survivorship may be more likely to use vitamin D supplements ( P < .05). Approximately 30% of breast cancer patients with blood levels recorded in their medical chart were potentially vitamin D deficient (<30 ng/mL). Vitamin D supplement use at study enrollment was associated with higher levels of self-reported health-related quality of life (HRQOL) at enrollment ( P < .05) and predicted better HRQOL at 6-month follow-up ( P < .05). Sufficient blood levels of vitamin D recorded between enrollment and follow-up were also associated with better HRQOL at follow-up ( P < .05). CONCLUSIONS:Vitamin D supplementation by breast cancer patients is common both during and after treatment for breast cancer, but deficiency may also be common. NO and conventional providers may be able to promote vitamin D sufficiency through vitamin D supplementation and by encouraging healthy solar exposure. Further studies should be undertaken examining whether vitamin D supplementation and higher blood levels might improve HRQOL among women with breast cancer in early survivorship.
journal_name
Integr Cancer Therjournal_title
Integrative cancer therapiesauthors
Andersen MR,Sweet E,Hager S,Gaul M,Dowd F,Standish LJdoi
10.1177/1534735418822056subject
Has Abstractpub_date
2019-01-01 00:00:00pages
1534735418822056eissn
1534-7354issn
1552-695Xjournal_volume
18pub_type
杂志文章abstract::Hesperidin is a natural compound that has chemoprotective effects in tumor cell lines and protective effects against hematotoxicity induced by cyclophosphamide. The aim of this study was to evaluate the effect of hesperidin on the antitumor effect of cyclophosphamide in tumor-bearing mice. Administration of hesperidin...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735412448959
更新日期:2012-09-01 00:00:00
abstract::Eupatorin is a polymethoxy flavone extracted from Orthosiphon stamineus and was reported to exhibit cytotoxic effects on several cancer cell lines. However, its effect as an anti-breast cancer agent in vivo has yet to be determined. This study aims to elucidate the potential of eupatorin as an anti-breast cancer agent...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735420935625
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Health care policies and guidelines that are clear and consistent with research evidence are important for maximizing clinical outcomes. To determine whether cancer centers in Canada and the United States had policies and/or guidelines about antioxidant use, and whether policies were aligned with the evidenc...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735415572884
更新日期:2015-07-01 00:00:00
abstract::There are increasing data showing that sonodynamic therapy (SDT), which refers to a synergistic effect of drugs and ultrasound, is a promising new modality for cancer treatment. However, few clinical data on SDT have been published. One reason is the lack of suitable drugs for clinical SDT use. Recently a new sonosens...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735408319065
更新日期:2008-06-01 00:00:00
abstract:AIM OF THE STUDY:Celastrus orbiculatus has been used as a folk medicine in China for the treatment of many diseases. In the laboratory, the ethyl acetate extract of Celastrus orbiculatus (COE) displays a wide range of anticancer functions. However, the inhibition of the metastasis mechanism of COE in gastric cancer cel...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735415572880
更新日期:2015-05-01 00:00:00
abstract::The effectiveness of traditional herbal medicine (THM) as treatment for nasopharyngeal cancer (NPC) has not been clearly demonstrated. The aim of this study is to assess the effectiveness of THM as adjunctive therapies for NPC using the results of randomized controlled trials (RCTs). Five electronic databases, includi...
journal_title:Integrative cancer therapies
pub_type: 杂志文章,meta分析,评审
doi:10.1177/1534735415572881
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:There is a lack of information on therapies recommended by naturopathic doctors (NDs) for lung and gastroesophageal cancer care. Study objectives were to: (1) identify the most common interventions considered for use by NDs; (2) identify interventions NDs recommend to support key therapeutic g...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735418759420
更新日期:2018-09-01 00:00:00
abstract::The acute apoptotic response to genotoxic carcinogens animal model has been extensively used to assess the ability of drugs and natural products like dietary components to promote apoptosis in the colon and protect against colorectal cancer (CRC). This work aimed to use this model to identify the main chemopreventativ...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735417699880
更新日期:2018-06-01 00:00:00
abstract:UNLABELLED:Objective Acquired chemoresistance is a major obstacle in the clinical management of ovarian cancer. Therefore, searching for alternative therapeutic modalities is urgently needed. Bitter melon (Momordica charantia) is a traditional dietary fruit, but its extract also shows potential medicinal values in huma...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735415611747
更新日期:2016-09-01 00:00:00
abstract::The circadian production of melatonin by the pineal gland during the night provides an inhibitory signal to tissue-isolated steroid receptor SR+ and - MCF-7 human breast cancer xenografts in female nude rats. A pivotal mechanism for melatonin's anticancer effects in vivo involves a melatonin receptor-mediated inhibiti...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735409352320
更新日期:2009-12-01 00:00:00
abstract::The British developmental biologist John Beard, DSc (1858-1924) is little remembered today. Yet, he made outstanding contributions to the life sciences. Beard deserves to be included among the leading biologists of the late 19th and early 20th century. He has been hailed as a forerunner of the present-day theory of th...
journal_title:Integrative cancer therapies
pub_type: 传,历史文章,杂志文章
doi:10.1177/1534735408326174
更新日期:2008-12-01 00:00:00
abstract::Cancers involving the oral cavity, head, and neck regions are often treated with cisplatin. In cancer therapy, the main target is to eliminate unwanted cancerous cells. However, reports on the nonselective nature of this drug have raised few concerns. Incorrect nutritional habits and lifestyle practices have been dire...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735416675950
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND:Malignant pleural effusion (MPE) is a common complication in most malignancies. Despite its frequent occurrence, current knowledge of MPE remains limited and the effect of the management is still unsatisfying. Traditional Chinese medicine (TCM) external treatment has unique advantages, such as quicker effica...
journal_title:Integrative cancer therapies
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1177/1534735416660193
更新日期:2017-12-01 00:00:00
abstract::In recent years, there has been an increased interest in complementary and alternative medicine (CAM) use among people with cancer. Many are looking for informed advice and desire communication with their physicians about CAM use. Communication is crucial in establishing trust with patients, gathering information, add...
journal_title:Integrative cancer therapies
pub_type: 杂志文章,评审
doi:10.1177/1534735410363706
更新日期:2010-06-01 00:00:00
abstract:BACKGROUND:Polysaccharide K, also known as PSK or Krestin, is derived from the Coriolus versicolor mushroom and is widely used in Japan as an adjuvant immunotherapy for a variety of cancer including lung cancer. Despite reported benefits, there has been no English language synthesis of PSK for lung cancer. To address t...
journal_title:Integrative cancer therapies
pub_type: 杂志文章,评审
doi:10.1177/1534735415572883
更新日期:2015-05-01 00:00:00
abstract::Cancer traditionally has been explained by the biomedical model; however, it is limited in comprehensively accounting for all factors in this disease. Recently, it has been suggested that a broader theoretical framework that includes psychosocial components in cancer is needed to complement the traditional approach. T...
journal_title:Integrative cancer therapies
pub_type: 杂志文章,评审
doi:10.1177/1534735402238188
更新日期:2002-12-01 00:00:00
abstract::Studies show an important relationship between vitamin D and malignancies, both in prevention and treatment. The extraskeletal actions of vitamin D relevant to oncology include being proapoptotic, antimetastatic, antiangiogenic, antiinflammatory, prodifferentiating, and immunomodulating. Widespread and severe vitamin ...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735408319062
更新日期:2008-06-01 00:00:00
abstract::Patients with familial adenomatous polyposis (FAP) depend on a lifelong endoscopic surveillance programme and prophylactic surgery, and usually suffer nutritional problems. Intestinal inflammation has been linked to both FAP and colorectal cancer. Epidemiological studies show a relationship between diet and inflammati...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735419846400
更新日期:2019-01-01 00:00:00
abstract::Cytoluminescent Therapy (CLT) is an unconventional form of photodynamic therapy (PDT), utilizing a second-generation chlorophyll-derived photosensitizing agent and whole-body illumination. Starting in late 2002, CLT was administered in Ireland to 48 patients. Illumination with lasers and light-emitting diodes followed...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735403259325
更新日期:2003-12-01 00:00:00
abstract::Background: Integrative oncology has proven to be a useful approach to control cancer symptoms and improve the quality of life (QoL) and overall health of patients, delivering integrated patient care at both physical and emotional levels. The objective of this randomized trial was to evaluate the effects of a triple i...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735420924757
更新日期:2020-01-01 00:00:00
abstract::Previous studies have shown that soybean fermentation products can act as cancer chemoprevention or therapeutic agents. In this study, the anticancer activities of a fermentation product of soybean, black bean, and green bean mixture (BN999) were investigated. We found that BN999 inhibited the growth of human breast c...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735412458828
更新日期:2013-05-01 00:00:00
abstract::Extracts of milk thistle have been recognized for centuries as "liver tonics" and are well-known to prevent or reverse hepatotoxicity of reactive drug metabolites or naturally occurring toxins. Milk thistle extracts are now under intense study in the experimental therapeutics of cancer for chemoprevention, treatment, ...
journal_title:Integrative cancer therapies
pub_type: 杂志文章,评审
doi:10.1177/1534735407301825
更新日期:2007-06-01 00:00:00
abstract::Although localized colon cancer is often successfully treated with surgery, advanced disease requires aggressive systemic therapy that has lower effectiveness. Approximately 30% to 75% of patients with colon cancer use complementary and alternative medicine (CAM), but there is limited formal evidence of survival effic...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735411406539
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVE:To evaluate the impact of participating in an integrative cancer care program at the Centre for Integrated Healing in Vancouver, British Columbia, on patients' lifestyle, quality of life, and overall well-being. STUDY DESIGN:A mixed-methods case study with a pre- and posttest design. No control group was uti...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735407313395
更新日期:2008-03-01 00:00:00
abstract::Background: Chemotherapy-induced peripheral neuropathy (CIPN) has no cure, but acupuncture may provide relief through its known neuromodulation or neuroendocrine adjustment. This review aimed to assess the efficacy of acupuncture in treating CIPN. Method: A literature review following the PRISMA Statement was performe...
journal_title:Integrative cancer therapies
pub_type: 杂志文章,meta分析
doi:10.1177/1534735419886662
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:To determine which mode of exercise is preferred by breast cancer survivors and to evaluate this response between graded exercise testing on a treadmill and on a cycle ergometer. METHODS:Twelve breast cancer survivors completed 2 maximal aerobic stress tests on separate days. The women completed a ramp protoco...
journal_title:Integrative cancer therapies
pub_type: 杂志文章,随机对照试验
doi:10.1177/1534735411433202
更新日期:2012-12-01 00:00:00
abstract:PURPOSE:Many botanical immunomodulators are used as adjuvants along with cancer chemotherapy. However, information on the impact of concurrent administration of such botanicals on pharmacokinetics of chemotherapy agents is inadequate. This study investigates inhibitory activities of 3 popular botanical adjuvants: ASPAR...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735413503551
更新日期:2014-03-01 00:00:00
abstract::This exploratory study is an attempt to define psychological attributes related to longer survival in patients with metastatic cancers. Previous published analyses have been limited in two ways. First, they have almost always been carried out on patients not receiving therapy; we have followed people receiving a year ...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735402001002006
更新日期:2002-06-01 00:00:00
abstract::For more than 200 years, biomedicine has approached the treatment of disease by studying disease processes (patho-genesis), inferring causal connections and developing specific approaches for therapeutically interfering with those processes. This pathogenic approach has been highly successful in acute and traumatic di...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735406295565
更新日期:2006-12-01 00:00:00
abstract::Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer that tends to affect young women and has a high propensity to metastasize. No targeted treatments are available for this type of breast cancer due to a lack of estrogen or progesterone receptors or overexpression of human epidermal growth f...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735420917444
更新日期:2020-01-01 00:00:00