Microarray expression profiles analysis revealed lncRNA OXCT1-AS1 promoted bladder cancer cell aggressiveness via miR-455-5p/JAK1 signaling.

abstract：:The main aim of this investigation was to determine whether a functional relationship existed between epidermal growth factor (EGF) and voltage-gated sodium channel (VGSC) upregulation, both associated with strongly metastatic prostate cancer cells. Incubation with EGF for 24 h more than doubled VGSC current density. ...

journal_title：Journal of cellular physiology

authors： Ding Y,Brackenbury WJ,Onganer PU,Montano X,Porter LM,Bates LF,Djamgoz MB

更新日期：2008-04-01 00:00:00

abstract：:In eukaryotes, the nuclear envelope (NE) physically separates nuclear components and activities from rest of the cell. The NE also provides rigidity to the nucleus and contributes to chromosome organization. At the same time, the NE is highly dynamic; it must change shape and rearrange its components during developmen...

journal_title：Journal of cellular physiology

authors： Meseroll RA,Cohen-Fix O

更新日期：2016-11-01 00:00:00

abstract：:Tumor necrosis factor-α (TNF-α) is a pluripotent signaling molecule. The biological effect of TNF-α includes slowing down osteogenic differentiation, which can lead to bone dysplasia in long-term inflammatory microenvironments. Signal transducer and activator of transcription 3 (STAT3)-interacting protein 1 (StIP1, al...

journal_title：Journal of cellular physiology

authors： Xu CP,Sun HT,Yang YJ,Cui Z,Wang J,Yu B,Wang FZ,Yang QP,Qi Y

更新日期：2019-08-01 00:00:00

abstract：:Heparan sulfate from the surface of a variety of mouse cells at different cell densities was examined by ion-exchange chromatography. The results of this analysis show that: (1) The heparan sulfate from new isolates of Swiss 3T3 cells transformed by SV40 virus (a DNA tumor virus) elutes from DEAE-cellulose at a lower ...

journal_title：Journal of cellular physiology

authors： Underhill CB,Keller JM

更新日期：1977-01-01 00:00:00

abstract：:Tumor progression is characterized by loss of cell adhesion and increase of invasion and metastasis. The cell adhesion molecule E-cadherin is frequently down-regulated or mutated in tumors. In addition to down-regulation of cell adhesion, degradation of the extracellular matrix by matrix metalloproteinases is necessar...

journal_title：Journal of cellular physiology

authors： Fuchs M,Hermannstädter C,Specht K,Knyazev P,Ullrich A,Rosivatz E,Busch R,Hutzler P,Höfler H,Luber B

更新日期：2005-03-01 00:00:00

abstract：:Acute myeloid leukemia (AML) is the most common type of leukemia in adults. AML cells secrete angiogenic factors to remodel vasculature and acquire chemoresistance; however, antiangiogenic drugs are often ineffective in AML treatment. Cancer cell-derived exosomes can induce angiogenesis, but their role in vascular rem...

journal_title：Journal of cellular physiology

authors： Wang B,Wang X,Hou D,Huang Q,Zhan W,Chen C,Liu J,You R,Xie J,Chen P,Huang H

更新日期：2019-07-01 00:00:00

abstract：:High temperature requirement A1 (HTRA1) is a serine protease playing a modulatory role in various cell processes, particularly in the regulation of transforming growth factor-β (TGF-β) signaling. A deleterious role in late-onset cerebral small vessel diseases (CSVDs) of heterozygous HTRA1 mutations, otherwise causativ...

journal_title：Journal of cellular physiology

authors： Fasano A,Formichi P,Taglia I,Bianchi S,Di Donato I,Battisti C,Federico A,Dotti MT

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Surgical stress has been suggested to facilitate colon cancer growth and metastasis. However, the precise mechanisms by which surgical trauma promotes colon cancer progression remain poorly understood. METHODS:To unravel the mechanisms underlying surgery-induced colon cancer progression, a syngenic transpla...

journal_title：Journal of cellular physiology

authors： Sun Z,Du C,Xu P,Miao C

更新日期：2019-04-01 00:00:00

abstract：:The zafirlukast has been reported to be anti-inflammatory and widely used to alleviate the symptoms of asthma. However, its influence on insulin secretion in pancreatic β-cells has not been investigated. Herein, we examined the effects of zafirlukast on insulin secretion and the potential underlying mechanisms. Among ...

journal_title：Journal of cellular physiology

authors： Hwang HJ,Park KS,Choi JH,Cocco L,Jang HJ,Suh PG

更新日期：2018-11-01 00:00:00

abstract：:Males and females differ across a broad spectrum of morphological, physiological, and behavioral characters. In fact, sexually dimorphic traits typically contribute the largest component of phenotypic variance in most taxa that use sex to reproduce. However, we know very little about the mechanisms that maintain these...

journal_title：Journal of cellular physiology

authors： Rigby N,Kulathinal RJ

更新日期：2015-10-01 00:00:00

abstract：:These are the reflections of a retired physician who was introduced to cellular physiology in 1947 at the University of Pennsylvania. I majored in Zoology. I took the required major courses, which were interesting but not exciting. I was a premedical student at the time. Fortunately I was introduced to cellular physio...

journal_title：Journal of cellular physiology

authors： Perelman A

更新日期：2015-11-01 00:00:00

abstract：:Trypsinized normal rat embryo fibroblasts and untrypsinized and trypsinized transformed rat fibroblasts have two orders of binding sites for bacterial glycolipid mR595. The high order sites fix 1--3 micrograms glycolipid mR595/10(5) cells and those of the low order fix about 6 microgram glycolipids mR595/10(6) cells. ...

journal_title：Journal of cellular physiology

authors： Lallier R,Trudel M,Brailovsky CA,Nigam VN

更新日期：1979-01-01 00:00:00

abstract：:Cell hybrids were formed between human diploid fibroblasts (HDF) and carcinogen-transformed HDF to determine the relationship among: (1) finite proliferative lifespan, which we define as an age-related failure of a population to achieve one population doubling in 4 weeks; (2) arrest in a senescent state, which we defi...

journal_title：Journal of cellular physiology

authors： Stein GH,Namba M,Corsaro CM

更新日期：1985-03-01 00:00:00

abstract：:We have previously shown that Compound 5 (Cpd 5), an inhibitor of protein phosphatase Cdc25A, inhibits Hep3B human hepatoma cell growth. We now show that hepatocyte growth factor (HGF), a hepatocyte growth stimulant, can strongly enhance Cpd 5-induced growth inhibition in Hep3B cells, and this enhancement in cell grow...

journal_title：Journal of cellular physiology

authors： Wang Z,Wang M,Carr BI

更新日期：2005-06-01 00:00:00

abstract：:Bradykinin (BK) is a potent short-lived effector belonging to a class of peptides known as kinins. It participates in inflammatory and vascular regulation and processes including angioedema, tissue permeability, vascular dilation, and smooth muscle contraction. BK exerts its biological effects through the activation o...

journal_title：Journal of cellular physiology

authors： Prado GN,Taylor L,Zhou X,Ricupero D,Mierke DF,Polgar P

更新日期：2002-12-01 00:00:00

abstract：:The development of efficient and repeatable protocols for biobanking and prolonged storage of cancer stem cells (CSCs), with minimum alterations in biological function, is valuable and desired, particularly for retrospective analysis and clinical applications. In particular, data regarding the effect of cryopreservatio...

journal_title：Journal of cellular physiology

authors： Eini L,Naseri M,Karimi-Busheri F,Bozorgmehr M,Ghods R,Madjd Z

更新日期：2020-03-01 00:00:00

abstract：:Eukaryotic translation initiation factor 5A (eIF5A) has a unique character: the presence of an unusual amino acid, hypusine, which is formed by post-translational modifications. Even before the identification of hypusination in eIF5A, the correlation between hypusine formation and protein synthesis, shifting cell prol...

journal_title：Journal of cellular physiology

authors： Parreiras-e-Silva LT,Luchessi AD,Reis RI,Oliver C,Jamur MC,Ramos RG,Oliveira EB,Curi R,Costa-Neto CM

更新日期：2010-11-01 00:00:00

abstract：:Cultured rat embryo cells were stimulated to rapidly release a small group of proteins that included several heat-shock proteins (hsp110, hsp71, hscp73) and nonmuscle actin. The extracellular proteins were analyzed by two-dimensional polyacrylamide gel electrophoresis. Heat-shocked cells released the same set of prote...

journal_title：Journal of cellular physiology

authors： Hightower LE,Guidon PT Jr

更新日期：1989-02-01 00:00:00

abstract：:Gastric cancer prognoses are persistently poor due to cancer's penchant to metastasize. As a crucial regulator of signal transducer and activator of transcription (STAT3) signaling, sirtuin 1's (SIRT1) function in gastric cancer has not been well understood. Here, we report upregulated expression of SIRT1 in tissues i...

journal_title：Journal of cellular physiology

authors： Zhang S,Yang Y,Huang S,Deng C,Zhou S,Yang J,Cao Y,Xu L,Yuan Y,Yang J,Chen G,Zhou L,Lv Y,Wang L,Zou X

更新日期：2019-09-01 00:00:00

abstract：:Cell- and matrix-related parameters, which characterize the aging and differentiation process of cartilage in vivo, were measured in cultured chick epiphyseal chondrocytes during maintenance in a suspension culture for 34 days. A gradual decrease in the rates of proliferation and an increase in the size of the cells w...

journal_title：Journal of cellular physiology

authors： Beit-Or A,Nevo Z,Kalina M,Eilam Y

更新日期：1990-08-01 00:00:00

abstract：:Confluent cultures of adult bovine aortic endothelial (ABAE), corneal endothelial (BCE), and fetal bovine heart endothelial (FBHE) cells form a monolayer of highly flattened, closely apposed, and nonoverlapping cells. In ABAE and BCE cultures, this is associated with a 50-fold decrease in the rate of DNA sythesis and ...

journal_title：Journal of cellular physiology

authors： Savion N,Vlodavsky I,Greenburg G,Gospodarowicz D

更新日期：1982-02-01 00:00:00

abstract：:Well-coupled mitochondria were isolated from a HuH13 line of human hepatoma cells and human liver tissue. The liver mitochondria showed a feeble glutamine oxidation activity in contrast to the hepatoma mitochondria, whereas they utilized glutamate well for the oxidative phosphorylation. In the liver mitochondria, glut...

journal_title：Journal of cellular physiology

authors： Matsuno T

更新日期：1991-08-01 00:00:00

abstract：:Activation of the epidermal growth factor receptor (EGFR) contributes to the pathogenesis of non-small-cell lung carcinomas (NSCLC) and gefitinib, a selective reversible EGFR inhibitor, is effective in treating patients with NSCLC. However, clinical resistance to gefitinib is a frequent occurrence highlighting the nee...

journal_title：Journal of cellular physiology

authors： Emdad L,Lebedeva IV,Su ZZ,Gupta P,Sarkar D,Settleman J,Fisher PB

更新日期：2007-02-01 00:00:00

abstract：:Atherosclerosis is one of the leading causes of morbidity and mortality, mainly due to the immune response triggered by the recruitment of monocytes/macrophages in the artery wall. Accumulating evidence have shown that matrix stiffness and oxidized low-density lipoproteins (ox-LDL) play important roles in atherosclero...

journal_title：Journal of cellular physiology

authors： Li J,Wang S,Li Y,Zhang N,Gribskov M,Zhang X,Lin M,Shao D,Zhang C,Dai L,Qin C,Duan X,Li J,Xu F,Yang H

更新日期：2020-09-01 00:00:00

abstract：:The platelet-derived growth factor (PDGF) binds via a defined amino acid sequence to heparin (Fager et al., 1992, In Vitro Cell. Dev. Biol., 28A:176-180) and the protein moiety of low density lipoproteins (LDL; apo B-100) via a similar sequence to chondroitin sulfate (Camejo et al., 1988, Arteriosclerosis Thromb., 8:3...

journal_title：Journal of cellular physiology

authors： Fager G,Camejo G,Olsson U,Ostergren-Lundén G,Lustig F,Bondjers G

更新日期：1995-05-01 00:00:00

abstract：:To evaluate the growth-inhibitory properties of the potent multi-kinase antagonist Regorafenib (Fluoro-Sorafenib), which was synthesized as a more potent Sorafenib, a Raf inhibitor and to determine whether similar mechanisms were involved, human hepatoma cell lines were grown in the presence or absence of Regorafanib ...

journal_title：Journal of cellular physiology

authors： Carr BI,Cavallini A,Lippolis C,D'Alessandro R,Messa C,Refolo MG,Tafaro A

更新日期：2013-02-01 00:00:00

abstract：:There are two known phosphorylation-mediated inactivation mechanisms for TRPC3 channels. Protein kinase G (PKG) inactivates TRPC3 by direct phosphorylation on Thr-11 and Ser-263 of the TRPC3 proteins, and protein kinase C (PKC) inactivates TRPC3 by phosphorylation on Ser-712. In the present study, we explored the rela...

journal_title：Journal of cellular physiology

authors： Kwan HY,Huang Y,Yao X

更新日期：2006-05-01 00:00:00

abstract：:Cholesterol is an important component for cell physiology. It regulates the fluidity of cell membranes and determines the physical and biochemical properties of proteins. In the central nervous system, cholesterol controls synapse formation and function and supports the saltatory conduction of action potential. In rec...

journal_title：Journal of cellular physiology

authors： Cartocci V,Servadio M,Trezza V,Pallottini V

更新日期：2017-02-01 00:00:00

abstract：:Over the past decade, a wide range of scientific investigations have been performed to reveal neuropathological aspects of cognitive disorders; however, only limited therapeutic approaches currently exist. The failures of conventional therapeutic options as well as the predicted dramatic rise in the prevalence of cogn...

journal_title：Journal of cellular physiology

authors： Farzaei MH,Bahramsoltani R,Abbasabadi Z,Braidy N,Nabavi SM

更新日期：2019-03-01 00:00:00

abstract：:Cells of rat parotid glands were maximally stimulated to initiate DNA synthesis by injecting into the animal a single dose of 25 to 150 mg of isoproterenol/kg of body weight. During the 18- to 21-hr prereplicative period following injection of the highest dose of the drug, there were two predominant and transient redi...

journal_title：Journal of cellular physiology

authors： Campos Gonzales R,Whitfield JF,Boynton AL,MacManus JP,Rixon RH

更新日期：1984-03-01 00:00:00