Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication.

Abstract:

:The ability of exosomes to transfer cargo from donor to acceptor cells, thereby triggering phenotypic changes in the latter, has generated substantial interest in the scientific community. However, the extent to which exosomes differ from other extracellular vesicles in terms of their biogenesis and functions remains ill-defined. Here, we discuss the current knowledge on the specificities of exosomes and other types of extracellular vesicles, and their roles as important agents of cell-to-cell communication.

journal_name

Nat Cell Biol

journal_title

Nature cell biology

authors

Mathieu M,Martin-Jaular L,Lavieu G,Théry C

doi

10.1038/s41556-018-0250-9

subject

Has Abstract

pub_date

2019-01-01 00:00:00

pages

9-17

issue

1

eissn

1465-7392

issn

1476-4679

pii

10.1038/s41556-018-0250-9

journal_volume

21

pub_type

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