Abstract：
AIM:To report the initial experience and outcomes of Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) as an adjunct to pre-hospital resuscitation of patients with exsanguinating pelvic haemorrhage. METHODS:Descriptive case series of consecutive adult patients, treated with pre-hospital Zone III REBOA by a physician-led pre-hospital trauma service, between January 2014 and July 2018. RESULTS:REBOA was attempted in 19 trauma patients (13 successful, six failed attempts) and two non-trauma patients (both successful) with exsanguinating pelvic haemorrhage. Trauma patients were severely injured (median ISS 34, IQR: 27-43) and profoundly hypotensive (median systolic blood pressure [SBP] 57, IQR: 40-68 mmHg). REBOA significantly improved blood pressure (Pre-REBOA median SBP 57, IQR: 35-67 mmHg versus Post- REBOA SBP 114, IQR: 86-132 mmHg; Median of differences 66, 95% CI: 25-74 mmHg; P < 0.001). REBOA was associated with significantly lower risk of pre-hospital cardiac arrest (REBOA 0/13 [0%] versus no REBOA 3/6 [50%], P = 0.021) and death from exsanguination (REBOA 0/13 [0%] versus no REBOA 4/6 [67%], P = 0.004), when compared to patients with a failed attempt. Successful REBOA was associated with improved survival (REBOA 8/13 [62%] versus no REBOA 2/6 [33%]; P = 0.350). Distal arterial thrombus requiring thrombectomy was common in the REBOA group (10/13, 77%). CONCLUSION:REBOA is a feasible pre-hospital resuscitation strategy for patients with exsanguinating pelvic haemorrhage. REBOA significantly improves blood pressure and may reduce the risk of pre-hospital hypovolaemic cardiac arrest and early death due to exsanguination. Distal arterial thrombus formation is common, and should be actively managed.
journal_name
Resuscitationjournal_title
Resuscitationauthors
Lendrum R,Perkins Z,Chana M,Marsden M,Davenport R,Grier G,Sadek S,Davies Gdoi
10.1016/j.resuscitation.2018.12.018subject
Has Abstractpub_date
2019-02-01 00:00:00pages
6-13eissn
0300-9572issn
1873-1570pii
S0300-9572(18)31110-9journal_volume
135pub_type
杂志文章相关文献
RESUSCITATION文献大全abstract：:An intrathoracic pressure regulator (ITPR) is a device that can be added to the external end of a tracheal tube to create controlled negative airway pressure between positive pressure ventilations. The resulting downward bias of the airway pressure baseline promotes increased venous return and enhanced circulation dur...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/j.resuscitation.2006.01.022
更新日期：2006-12-01 00:00:00
abstract：AIM OF THE STUDY:Sternal and rib fractures are frequent complications caused by chest compressions during cardiopulmonary resuscitation (CPR). This study aimed to investigate the potential association of CPR-related thoracic and abdominal injuries and compression depth measured with an accelerometer. METHODS:We analys...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/j.resuscitation.2013.02.015
更新日期：2013-06-01 00:00:00
abstract：:While limiting and forgoing therapy at the end of life is now accepted on medical, ethical, moral and legal grounds, many Americans continue to die with heroic measures being taken to prevent their death. Recent studies have demonstrated that physicians frequently attend to their patients without knowledge of their pr...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/s0300-9572(99)00114-8
更新日期：1999-11-01 00:00:00
abstract：:Pharmacological doses (40-160 micrograms/kg) of adrenocorticotropic hormone (ACTH) intravenously injected to urethane-anesthetized rats subjected to otherwise lethal hemorrhagic shock (mean arterial pressure stabilized at 20-25 mmHg) promptly restore blood pressure to about the pre-bleeding values, and prevent death (...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/0300-9572(89)90029-4
更新日期：1989-12-01 00:00:00
abstract：OBJECTIVE:Survival after out-of-hospital cardiac arrest (OOHCA) in an urban environment is directly proportional to speed of defibrillation and effective bystander cardiopulmonary resuscitation (CPR). We hypothesized that the hospital discharge rate from rural OOHCA was affected by the same factors. METHODS:We studied...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/s0300-9572(02)00273-3
更新日期：2003-01-01 00:00:00
abstract：AIM:The purpose of this study was to determine how long it takes rescuers to complete five cycles of cardiopulmonary resuscitation (CPR) using a compression-ventilation (CV) ratio of 30:2. MATERIALS AND METHODS:Twenty subjects, who were all members of the medical service at a motor racing circuit and trained in basic ...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/j.resuscitation.2006.02.018
更新日期：2006-10-01 00:00:00
abstract：BACKGROUND:The epidemiology and outcome after out-of-hospital cardiac arrest (OHCA) varies across Europe. Following on from EuReCa ONE, the aim of this study was to further explore the incidence of and outcomes from OHCA in Europe and to improve understanding of the role of the bystander. METHODS:This prospective, mul...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/j.resuscitation.2019.12.042
更新日期：2020-03-01 00:00:00
abstract：AIM OF THE STUDY:Establishing functional residual capacity (FRC) during positive pressure ventilation (PPV) of apnoeic neonates is critical for survival. This may be difficult due to liquid-filled airways contributing to low lung compliance. The objectives were to describe initial PPV, changes in lung compliance and es...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/j.resuscitation.2020.05.033
更新日期：2020-08-01 00:00:00
abstract：AIM:Refractory ventricular fibrillation, resistant to conventional cardiopulmonary resuscitation (CPR), is a life threatening rhythm encountered in the emergency department. Although previous reports suggest the use of extracorporeal CPR can improve the clinical outcomes in patients with prolonged cardiac arrest, the e...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/j.resuscitation.2015.04.016
更新日期：2015-07-01 00:00:00
abstract：:Myocardial perfusion pressure, defined as the aortic diastolic pressure minus the right atrial diastolic pressure, correlates with coronary blood flow during cardiopulmonary resuscitation (CPR) and predicts initial resuscitation success. Whether this hemodynamic parameter can predict 24-h survival is not known. We exa...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/0300-9572(88)90111-6
更新日期：1988-10-01 00:00:00
abstract：:Continuous balloon occlusion of the descending aorta is an experimental method that may improve blood flow to the myocardium and the brain during cardiopulmonary resuscitation (CPR). The aim of the present investigation was to evaluate the effects of this intervention on haemodynamics and the frequency of restoration ...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/s0300-9572(99)00021-0
更新日期：1999-04-01 00:00:00
abstract：INTRODUCTION:Survival from out of hospital cardiac arrest (OHCA) is highest in victims with shockable rhythms when early CPR and rapid defibrillation are provided. However, a subset of individuals present with ventricular fibrillation (VF) that does not respond to defibrillation (refractory VF). One intervention that m...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/j.resuscitation.2016.08.002
更新日期：2016-11-01 00:00:00
abstract：:In a prospective randomised study we investigated end-tidal carbon dioxide levels during standard versus active compression-decompression (ACD) cardiopulmonary resuscitation (CPR) assuming that the end-tital carbon dioxide reflects cardiac output during resuscitation. In each group 60 patients with out-of-hospital car...
journal_title：Resuscitation
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0300-9572(98)00106-3
更新日期：1998-10-01 00:00:00
abstract：AIM:To evaluate the gonadal hormones in patients with return of spontaneous circulation (ROSC) after cardiac arrest following prospectively good (cerebral-performance category [CPC] 1-2) and poor (CPC 3-5) neurologic outcomes. METHODS:The patients in an emergency center who had been admitted to the center's intensive ...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/j.resuscitation.2012.10.022
更新日期：2013-05-01 00:00:00
abstract：INTRODUCTION:Telephone cardiopulmonary resuscitation (CPR) advice aims to increase the quality and quantity of bystander CPR, one of the few interventions shown to improve outcome in cardiac arrest. We evaluated a current telephone protocol (based on 2000 ILCOR guidelines) to assess the effectiveness of verbal CPR inst...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/j.resuscitation.2006.11.007
更新日期：2007-07-01 00:00:00
abstract：BACKGROUND:In volume- or pressure-controlled hemorrhagic shock (HS) a bolus intravenous infusion of hypertonic/hyperoncotic solution (HHS) proved beneficial compared to isotonic crystalloid solutions. During uncontrolled HS in animals, however, HHS by bolus increased blood pressure unpredictably, and increased blood lo...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/j.resuscitation.2004.10.012
更新日期：2005-04-01 00:00:00
abstract：:A clinical study of some biological and biochemical factors was carried out on patients with acute myocardial infarction. It was shown that: (i) the plasma viscosity was highly correlated to the clinical evolution of myocardial infarction; (ii) the variations of plasma viscosity were related to changes in the connecti...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/0300-9572(76)90041-1
更新日期：1976-01-01 00:00:00
abstract：BACKGROUND:the objective was to determine clinical characteristics that can quickly distinguish sudden death from massive pulmonary embolism (MPE) from other causes of sudden death. METHODS AND RESULTS:all medical examiner reports from Charlotte, NC from 1992 to 1999 (n=4926) were hand-searched for cases of sudden dea...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/s0300-9572(00)00374-9
更新日期：2001-06-01 00:00:00
abstract：AIM:We aimed to describe characteristics associated with rescue from drowning as reported by the Swedish Fire and Rescue Services (SFARS) and their association with survival from the Out of Hospital Cardiac Arrest (OHCA) registry. METHOD:This retrospective study is based on the OHCA registry and the Swedish Civil Cont...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/j.resuscitation.2012.05.025
更新日期：2012-09-01 00:00:00
abstract：INTRODUCTION:In various motion pictures, medical TV shows and internet chatrooms, non-medical devices were presented as tools for life-saving cricothyroidotomies. However, there is uncertainty about whether it is possible for a bystander to perform a cricothyroidotomy and maintain gas exchange using improvised househol...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/j.resuscitation.2016.10.015
更新日期：2017-01-01 00:00:00
abstract：BACKGROUND:Animal studies and pathophysiological considerations suggest that therapeutic hypothermia after cardiopulmonary resuscitation is the more effective the earlier it is induced. Therefore this study is sought to examine whether pharmacological facilitated hypothermia by administration of 5'-adenosine monophosph...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/j.resuscitation.2014.05.030
更新日期：2014-09-01 00:00:00
abstract：BACKGROUND:In mechanically ventilated (MV) cardiac arrest (CA) survivors admitted to the intensive care unit (ICU) avoidance of hypoxia is considered crucial. However, avoidance of hyperoxia may also be important. A conservative approach to oxygen therapy may reduce exposure to both. METHODS:We evaluated the introduct...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/j.resuscitation.2015.11.026
更新日期：2016-04-01 00:00:00
abstract：AIM:Spaced training programs employ short, frequent CPR training sessions to improve provider skills. The optimum training frequency for CPR skill acquisition and retention has not been determined. We aimed to determine the training interval associated with the highest quality CPR performance at one year. METHODS:Part...
journal_title：Resuscitation
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.resuscitation.2018.10.033
更新日期：2019-02-01 00:00:00
abstract：:The results of intensive therapy and temporary organ substitution by hemoperfusion through a suspension of active hepatocytes in 126 patients suffering from acute hepatic insufficiency (AHI) induced by virus B hepatitis, virus non-A, non-B hepatitis, acute toxic hepatitis, active liver cirrhosis, sepsis leptospirosis ...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/0300-9572(89)90115-9
更新日期：1989-10-01 00:00:00
abstract：SETTING:Sudden Cardiac Death accounts for approximately 5000 deaths in Ireland each year. Nationally, out-of-hospital cardiac arrest has a very low resuscitation rate, reported at less than 5%. Ireland has a well developed general practice network which routinely manages emergencies arising in the community setting. Ho...
journal_title：Resuscitation
pub_type： 杂志文章,多中心研究
doi：10.1016/j.resuscitation.2009.07.010
更新日期：2009-11-01 00:00:00
abstract：:A possible diagnostic role of procalcitonin (PCT) as a marker for ventilator associated pneumonia (VAP) in patients with an already triggered acute phase response after successful cardiopulmonary resuscitation (CPR) was investigated. In 28 patients with return of spontaneous circulation (ROSC) after out of hospital CP...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/s0300-9572(02)00008-4
更新日期：2002-05-01 00:00:00
abstract：:"Bystanders" or lay persons are typically the first caregivers to attend to a victim of out-of-hospital cardiopulmonary arrest. Astronaut crew medical officers (CMO) play a similar role to bystanders aboard the International Space Station (ISS). Studies have demonstrated the importance of bystander cardiopulmonary res...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/j.resuscitation.2006.07.027
更新日期：2007-04-01 00:00:00
abstract：:Voluntary copper poisoning is a rare mode of suicide. We report a case of copper sulphate poisoning in a patient presenting delusions with mystic demands for purification. The initial gastrointestinal symptoms were followed by intravascular haemolysis and renal failure. The course was favourable after symptomatic trea...
journal_title：Resuscitation
pub_type： 杂志文章,评审
doi：10.1016/j.resuscitation.2008.02.017
更新日期：2008-07-01 00:00:00
abstract：PURPOSE:Mechanical chest compression devices, such as the AutoPulse(®), have been developed to overcome problems associated with manual CPR (M-CPR). Animal and human studies have shown that AutoPulse CPR improves hemodynamic parameters over M-CPR. However, human studies conducted in the prehospital setting have conflic...
journal_title：Resuscitation
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.resuscitation.2010.11.013
更新日期：2011-03-01 00:00:00
abstract：INTRODUCTION:Rapid response systems are commonly employed by hospitals to identify and respond to deteriorating patients outside of the intensive care unit. Controversy exists about the benefits of rapid response systems. AIMS:We aimed to review the current state of the rapid response literature, including evolving as...
journal_title：Resuscitation
pub_type： 杂志文章,评审
doi：10.1016/j.resuscitation.2018.05.013
更新日期：2018-07-01 00:00:00
