Author Correction: nc886 is induced by TGF-β and suppresses the microRNA pathway in ovarian cancer.


:In the original version of the Supplementary Information file associated with this Article, Supplementary Fig. 18 panel b was inadvertently replaced with a duplicate of panel a. The error has now been fixed and the corrected version of the Supplementary Information PDF is available to download from the HTML version of the Article.


Nat Commun


Nature communications


Ahn JH,Lee HS,Lee JS,Lee YS,Park JL,Kim SY,Hwang JA,Kunkeaw N,Jung SY,Kim TJ,Lee KS,Jeon SH,Lee I,Johnson BH,Choi JH,Lee YS




Has Abstract


2018-12-19 00:00:00












  • Self-similarity of contact line depinning from textured surfaces.

    abstract::The mobility of drops on surfaces is important in many biological and industrial processes, but the phenomena governing their adhesion, which is dictated by the morphology of the three-phase contact line, remain unclear. Here we describe a technique for measuring the dynamic behaviour of the three-phase contact line a...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Paxson AT,Varanasi KK

    更新日期:2013-01-01 00:00:00

  • Targeted activation of diverse CRISPR-Cas systems for mammalian genome editing via proximal CRISPR targeting.

    abstract::Bacterial CRISPR-Cas systems comprise diverse effector endonucleases with different targeting ranges, specificities and enzymatic properties, but many of them are inactive in mammalian cells and are thus precluded from genome-editing applications. Here we show that the type II-B FnCas9 from Francisella novicida posses...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Chen F,Ding X,Feng Y,Seebeck T,Jiang Y,Davis GD

    更新日期:2017-04-07 00:00:00

  • Coexistence of distinct skyrmion phases observed in hybrid ferromagnetic/ferrimagnetic multilayers.

    abstract::Materials hosting magnetic skyrmions at room temperature could enable compact and energetically-efficient storage such as racetrack memories, where information is coded by the presence/absence of skyrmions forming a moving chain through the device. The skyrmion Hall effect leading to their annihilation at the racetrac...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Mandru AO,Yıldırım O,Tomasello R,Heistracher P,Penedo M,Giordano A,Suess D,Finocchio G,Hug HJ

    更新日期:2020-12-11 00:00:00

  • Self-assembly of DNA nanotubes with controllable diameters.

    abstract::The synthesis of DNA nanotubes is an important area in nanobiotechnology. Different methods to assemble DNA nanotubes have been reported, and control over the width of the nanotubes has been achieved by programmed subunits of DNA tiles. Here we report the self-assembly of DNA nanotubes with controllable diameters. The...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Wilner OI,Orbach R,Henning A,Teller C,Yehezkeli O,Mertig M,Harries D,Willner I

    更新日期:2011-11-15 00:00:00

  • An in vivo platform to select and evolve aggregation-resistant proteins.

    abstract::Protein biopharmaceuticals are highly successful, but their utility is compromised by their propensity to aggregate during manufacture and storage. As aggregation can be triggered by non-native states, whose population is not necessarily related to thermodynamic stability, prediction of poorly-behaving biologics is di...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Ebo JS,Saunders JC,Devine PWA,Gordon AM,Warwick AS,Schiffrin B,Chin SE,England E,Button JD,Lloyd C,Bond NJ,Ashcroft AE,Radford SE,Lowe DC,Brockwell DJ

    更新日期:2020-04-14 00:00:00

  • Highly efficient RNA-guided base editing in rabbit.

    abstract::Cytidine base editors (CBEs) and adenine base editors (ABEs), composed of a cytidine deaminase or an evolved adenine deaminase fused to Cas9 nickase, enable the conversion of C·G to T·A or A·T to G·C base pair in organisms, respectively. Here, we show that BE3 and ABE7.10 systems can achieve a targeted mutation effici...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Liu Z,Chen M,Chen S,Deng J,Song Y,Lai L,Li Z

    更新日期:2018-07-13 00:00:00

  • High residual carriage of vaccine-serotype Streptococcus pneumoniae after introduction of pneumococcal conjugate vaccine in Malawi.

    abstract::There are concerns that pneumococcal conjugate vaccines (PCVs) in sub-Saharan Africa sub-optimally interrupt Streptococcus pneumoniae vaccine-serotype (VT) carriage and transmission. Here we assess PCV carriage using rolling, prospective nasopharyngeal carriage surveys between 2015 and 2018, 3.6-7.1 years after Malawi...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Swarthout TD,Fronterre C,Lourenço J,Obolski U,Gori A,Bar-Zeev N,Everett D,Kamng'ona AW,Mwalukomo TS,Mataya AA,Mwansambo C,Banda M,Gupta S,Diggle P,French N,Heyderman RS

    更新日期:2020-05-06 00:00:00

  • Large spatial extension of the zero-energy Yu-Shiba-Rusinov state in a magnetic field.

    abstract::Various promising qubit concepts have been put forward recently based on engineered superconductor subgap states like Andreev bound states, Majorana zero modes or the Yu-Shiba-Rusinov (Shiba) states. The coupling of these subgap states via a superconductor strongly depends on their spatial extension and is an essentia...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Scherübl Z,Fülöp G,Moca CP,Gramich J,Baumgartner A,Makk P,Elalaily T,Schönenberger C,Nygård J,Zaránd G,Csonka S

    更新日期:2020-04-14 00:00:00

  • Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry.

    abstract::Diverse entry inhibitors targeting the gp120 subunit of the HIV-1 envelope (Env) trimer have been developed including BMS-626529, also called temsavir, a prodrug version of which is currently in phase III clinical trials. Here we report the characterization of a panel of small-molecule inhibitors including BMS-818251,...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Lai YT,Wang T,O'Dell S,Louder MK,Schön A,Cheung CSF,Chuang GY,Druz A,Lin B,McKee K,Peng D,Yang Y,Zhang B,Herschhorn A,Sodroski J,Bailer RT,Doria-Rose NA,Mascola JR,Langley DR,Kwong PD

    更新日期:2019-01-03 00:00:00

  • Facile scission of isonitrile carbon-nitrogen triple bond using a diborane(4) reagent.

    abstract::Transition metal reagents and catalysts are generally effective to cleave all three bonds (one σ and two π) in a triple bond despite its high bonding energy. Recently, chemistry of single-bond cleavage by using main-group element compounds is rapidly being developed in the absence of transition metals. However, the cl...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Asakawa H,Lee KH,Lin Z,Yamashita M

    更新日期:2014-06-26 00:00:00

  • The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding.

    abstract::Heat shock protein-90 (Hsp90) is an essential molecular chaperone in eukaryotes involved in maintaining the stability and activity of numerous signalling proteins, also known as clients. Hsp90 ATPase activity is essential for its chaperone function and it is regulated by co-chaperones. Here we show that the tumour sup...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Woodford MR,Dunn DM,Blanden AR,Capriotti D,Loiselle D,Prodromou C,Panaretou B,Hughes PF,Smith A,Ackerman W,Haystead TA,Loh SN,Bourboulia D,Schmidt LS,Marston Linehan W,Bratslavsky G,Mollapour M

    更新日期:2016-06-29 00:00:00

  • High-throughput cell and spheroid mechanics in virtual fluidic channels.

    abstract::Microfluidics by soft lithography has proven to be of key importance for biophysics and life science research. While being based on replicating structures of a master mold using benchtop devices, design modifications are time consuming and require sophisticated cleanroom equipment. Here, we introduce virtual fluidic c...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Panhwar MH,Czerwinski F,Dabbiru VAS,Komaragiri Y,Fregin B,Biedenweg D,Nestler P,Pires RH,Otto O

    更新日期:2020-05-04 00:00:00

  • CRISPR-Cas9 genome editing induces megabase-scale chromosomal truncations.

    abstract::CRISPR-Cas9 is a promising technology for genome editing. Here we use Cas9 nuclease-induced double-strand break DNA (DSB) at the UROS locus to model and correct congenital erythropoietic porphyria. We demonstrate that homology-directed repair is rare compared with NHEJ pathway leading to on-target indels and causing u...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Cullot G,Boutin J,Toutain J,Prat F,Pennamen P,Rooryck C,Teichmann M,Rousseau E,Lamrissi-Garcia I,Guyonnet-Duperat V,Bibeyran A,Lalanne M,Prouzet-Mauléon V,Turcq B,Ged C,Blouin JM,Richard E,Dabernat S,Moreau-Gaudry F,

    更新日期:2019-03-08 00:00:00

  • MED26 regulates the transcription of snRNA genes through the recruitment of little elongation complex.

    abstract::Regulation of transcription elongation by RNA polymerase II (Pol II) is a key regulatory step in gene transcription. Recently, the little elongation complex (LEC)-which contains the transcription elongation factor ELL/EAF-was found to be required for the transcription of Pol II-dependent small nuclear RNA (snRNA) gene...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Takahashi H,Takigawa I,Watanabe M,Anwar D,Shibata M,Tomomori-Sato C,Sato S,Ranjan A,Seidel CW,Tsukiyama T,Mizushima W,Hayashi M,Ohkawa Y,Conaway JW,Conaway RC,Hatakeyama S

    更新日期:2015-01-09 00:00:00

  • CRISPR/Cas9-mediated glycolate oxidase disruption is an efficacious and safe treatment for primary hyperoxaluria type I.

    abstract::CRISPR/Cas9 technology offers novel approaches for the development of new therapies for many unmet clinical needs, including a significant number of inherited monogenic diseases. However, in vivo correction of disease-causing genes is still inefficient, especially for those diseases without selective advantage for cor...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Zabaleta N,Barberia M,Martin-Higueras C,Zapata-Linares N,Betancor I,Rodriguez S,Martinez-Turrillas R,Torella L,Vales A,Olagüe C,Vilas-Zornoza A,Castro-Labrador L,Lara-Astiaso D,Prosper F,Salido E,Gonzalez-Aseguinolaza G,R

    更新日期:2018-12-21 00:00:00

  • Neurogenetic profiles delineate large-scale connectivity dynamics of the human brain.

    abstract::Experimental and modeling work of neural activity has described recurrent and attractor dynamic patterns in cerebral microcircuits. However, it is still poorly understood whether similar dynamic principles exist or can be generalizable to the large-scale level. Here, we applied dynamic graph theory-based analyses to e...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Diez I,Sepulcre J

    更新日期:2018-09-24 00:00:00

  • The halogen bond with isocyano carbon reduces isocyanide odor.

    abstract::Predominantly, carbon atoms of various species function as acceptors of noncovalent interactions when they are part of a π-system. Here, we report on the discovery of a halogen bond involving the isocyano carbon lone pair. The co-crystallization or mechanochemical liquid-assisted grinding of model mesityl isocyanide w...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Mikherdov AS,Novikov AS,Boyarskiy VP,Kukushkin VY

    更新日期:2020-06-10 00:00:00

  • A selective inhibitor of mitofusin 1-βIIPKC association improves heart failure outcome in rats.

    abstract::We previously demonstrated that beta II protein kinase C (βIIPKC) activity is elevated in failing hearts and contributes to this pathology. Here we report that βIIPKC accumulates on the mitochondrial outer membrane and phosphorylates mitofusin 1 (Mfn1) at serine 86. Mfn1 phosphorylation results in partial loss of its ...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Ferreira JCB,Campos JC,Qvit N,Qi X,Bozi LHM,Bechara LRG,Lima VM,Queliconi BB,Disatnik MH,Dourado PMM,Kowaltowski AJ,Mochly-Rosen D

    更新日期:2019-01-18 00:00:00

  • Atypical chemoreceptor arrays accommodate high membrane curvature.

    abstract::The prokaryotic chemotaxis system is arguably the best-understood signaling pathway in biology. In all previously described species, chemoreceptors organize into a hexagonal (P6 symmetry) extended array. Here, we report an alternative symmetry (P2) of the chemotaxis apparatus that emerges from a strict linear organiza...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Muok AR,Ortega DR,Kurniyati K,Yang W,Maschmann ZA,Sidi Mabrouk A,Li C,Crane BR,Briegel A

    更新日期:2020-11-13 00:00:00

  • Myths and reality of HPbI3 in halide perovskite solar cells.

    abstract::All-inorganic perovskites have a special place in halide perovskite family because of their potential for better stability. However, the representative cesium lead iodide (CsPbI3) is metastable and spontaneously converts to the non-perovskite structure at room temperature. Here, we demonstrate that what appears to be ...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Ke W,Spanopoulos I,Stoumpos CC,Kanatzidis MG

    更新日期:2018-11-14 00:00:00

  • Multi-cohort study identifies social determinants of systemic inflammation over the life course.

    abstract::Chronic inflammation has been proposed as having a prominent role in the construction of social inequalities in health. Disentangling the effects of early life and adulthood social disadvantage on inflammation is key in elucidating biological mechanisms underlying socioeconomic disparities. Here we explore the relatio...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Berger E,Castagné R,Chadeau-Hyam M,Bochud M,d'Errico A,Gandini M,Karimi M,Kivimäki M,Krogh V,Marmot M,Panico S,Preisig M,Ricceri F,Sacerdote C,Steptoe A,Stringhini S,Tumino R,Vineis P,Delpierre C,Kelly-Irving M

    更新日期:2019-02-15 00:00:00

  • A facile route to old and new cyclophanes via self-assembly and capture.

    abstract::Cyclophanes are a venerable class of macrocyclic and/or cage compounds that often feature high strain, unusual conformations and quite surprising properties, many of which are legendary in physical organic chemistry. However, the discovery of new, diverse cyclophanes and derivatives has been hindered by syntheses that...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Collins MS,Carnes ME,Nell BP,Zakharov LN,Johnson DW

    更新日期:2016-04-04 00:00:00

  • Mesopelagic fishes dominate otolith record of past two millennia in the Santa Barbara Basin.

    abstract::The mesopelagic (200-1000 m) separates the productive upper ocean from the deep ocean, yet little is known of its long-term dynamics despite recent research that suggests fishes of this zone likely dominate global fish biomass and contribute to the downward flux of carbon. Here we show that mesopelagic fishes dominate...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Jones WA,Checkley DM Jr

    更新日期:2019-10-08 00:00:00

  • High-speed AFM height spectroscopy reveals µs-dynamics of unlabeled biomolecules.

    abstract::Dynamics are fundamental to the functions of biomolecules and can occur on a wide range of time and length scales. Here we develop and apply high-speed AFM height spectroscopy (HS-AFM-HS), a technique whereby we monitor the sensing of a HS-AFM tip at a fixed position to directly detect the motions of unlabeled molecul...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Heath GR,Scheuring S

    更新日期:2018-11-26 00:00:00

  • Shaping metallic glasses by electromagnetic pulsing.

    abstract::With damage tolerance rivalling advanced engineering alloys and thermoplastic forming capabilities analogous to conventional plastics, metallic glasses are emerging as a modern engineering material. Here, we take advantage of their unique electrical and rheological properties along with the classic Lorentz force conce...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Kaltenboeck G,Demetriou MD,Roberts S,Johnson WL

    更新日期:2016-02-08 00:00:00

  • Changing temporal context in human temporal lobe promotes memory of distinct episodes.

    abstract::Memories of experiences that occur around the same time are linked together by a shared temporal context, represented by shared patterns of neural activity. However, shared temporal context may be problematic for selective retrieval of specific memories. Here, we examine intracranial EEG (iEEG) in the human temporal l...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: El-Kalliny MM,Wittig JH Jr,Sheehan TC,Sreekumar V,Inati SK,Zaghloul KA

    更新日期:2019-01-14 00:00:00

  • CD8+ T cells stimulate Na-Cl co-transporter NCC in distal convoluted tubules leading to salt-sensitive hypertension.

    abstract::Recent studies suggest a role for T lymphocytes in hypertension. However, whether T cells contribute to renal sodium retention and salt-sensitive hypertension is unknown. Here we demonstrate that T cells infiltrate into the kidney of salt-sensitive hypertensive animals. In particular, CD8+ T cells directly contact the...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Liu Y,Rafferty TM,Rhee SW,Webber JS,Song L,Ko B,Hoover RS,He B,Mu S

    更新日期:2017-01-09 00:00:00

  • Quantifying net loss of global mangrove carbon stocks from 20 years of land cover change.

    abstract::Mangrove forests hold some of the highest densities of carbon recorded in any ecosystem, but have experienced widespread deforestation through conversion to aquaculture and agriculture. Alongside deforestation, mangroves have shown simultaneous natural expansion in some parts of the world, and considerable investments...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Richards DR,Thompson BS,Wijedasa L

    更新日期:2020-08-26 00:00:00

  • Oscillatory integration windows in neurons.

    abstract::Oscillatory synchrony among neurons occurs in many species and brain areas, and has been proposed to help neural circuits process information. One hypothesis states that oscillatory input creates cyclic integration windows: specific times in each oscillatory cycle when postsynaptic neurons become especially responsive...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Gupta N,Singh SS,Stopfer M

    更新日期:2016-12-15 00:00:00

  • Clonal selection in the human Vδ1 T cell repertoire indicates γδ TCR-dependent adaptive immune surveillance.

    abstract::γδ T cells are considered to be innate-like lymphocytes that respond rapidly to stress without clonal selection and differentiation. Here we use next-generation sequencing to probe how this paradigm relates to human Vδ2neg T cells, implicated in responses to viral infection and cancer. The prevalent Vδ1 T cell recepto...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Davey MS,Willcox CR,Joyce SP,Ladell K,Kasatskaya SA,McLaren JE,Hunter S,Salim M,Mohammed F,Price DA,Chudakov DM,Willcox BE

    更新日期:2017-03-01 00:00:00