Important Therapeutic Considerations in T1b Penile Cancer: Prognostic Significance and Adherence to Treatment Guidelines.

abstract：BACKGROUND:Neoadjuvant endocrine therapy (NET) is effective in downstaging large hormone receptor-positive (HR+) breast cancers and increasing rates of breast-conserving surgery (BCS), but data regarding nodal pathologic complete response (pCR) are sparse. We reported nodal and breast downstaging rates with NET, and co...

journal_title：Annals of surgical oncology

authors： Montagna G,Sevilimedu V,Fornier M,Jhaveri K,Morrow M,Pilewskie ML

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:FOXC2 has been implicated in cancer progression through its induction of epithelial-to-mesenchymal transition. We analyzed the clinical significance of FOXC2 in esophageal cancer cases, in which early distant metastasis or invasion to nearby organs is an obstacle to treatment. METHODS:Quantitative reverse t...

journal_title：Annals of surgical oncology

authors： Nishida N,Mimori K,Yokobori T,Sudo T,Tanaka F,Shibata K,Ishii H,Doki Y,Mori M

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Preoperative differentiation between high-grade malignancy and others (benign or low-grade tumors) is more important than differentiation between malignant and benign tumors for surgical planning, treatment outcome, and prognosis in salivary gland tumors. Fine needle aspiration cytology (FNAC) has a relative...

journal_title：Annals of surgical oncology

authors： Kim BY,Hyeon J,Ryu G,Choi N,Baek CH,Ko YH,Jeong HS

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Sentinel lymph node biopsy (SLNB) is recommended for intermediate thickness melanoma, but for thick melanoma, guidelines are less definitive about the use of SLNB in this population. We present a study on thick melanoma evaluating for prognostic factors. PATIENTS AND METHODS:The Sentinel Lymph Node Working ...

journal_title：Annals of surgical oncology

authors： Han D,Han G,Duque MT,Morrison S,Leong SP,Kashani-Sabet M,Vetto J,White R,Schneebaum S,Pockaj B,Mozzillo N,Sondak VK,Zager JS

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND:Response to chemotherapy and anatomical spread are significant prognostic factors in patients with esophageal squamous cell carcinoma (ESCC) treated by chemotherapy then surgery. Predicting the response to chemotherapy would allow significant optimization of cancer treatment. METHODS:Genomic mutation and pr...

journal_title：Annals of surgical oncology

authors： Yamasaki M,Miyata H,Fujiwara Y,Takiguchi S,Nakajima K,Nishida T,Yasuda T,Matsuyama J,Mori M,Doki Y

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Melanoma that involves the upper gastrointestinal (GI) tract is rare and studies relating to endoscopic and pathologic findings with clinical outcomes are lacking. We reviewed the gross and microscopic patterns of the upper GI tract in primary and metastatic melanoma, and examined their association with clin...

journal_title：Annals of surgical oncology

authors： Ahn JY,Hwang HS,Park YS,Kim HR,Jung HY,Kim JH,Lee SE,Kim MA

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Isolated limb infusion (ILI) with cytotoxic drugs has been used since 1992 to treat advanced melanoma confined to a limb. Over this time the technique has undergone progressive modification. In this study we evaluated our experience with ILI by analyzing outcome and toxicity from an "early" and a "late" trea...

journal_title：Annals of surgical oncology

authors： Huismans AM,Kroon HM,Kam PC,Thompson JF

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:The lymph node (LN) ratio (LNR) and the log odds of positive LNs (LODDS) have been proposed as sensitive prognosticators in patients with primary gastric cancer, especially in patients with an insufficient number of harvested LNs. We investigated the association of LNR and LODDS with survival in patients wit...

journal_title：Annals of surgical oncology

authors： Kano K,Yamada T,Yamamoto K,Komori K,Watanabe H,Takahashi K,Maezawa Y,Fujikawa H,Numata M,Aoyama T,Tamagawa H,Cho H,Yukawa N,Yoshikawa T,Rino Y,Masuda M,Ogata T,Oshima T

更新日期：2021-01-03 00:00:00

abstract：BACKGROUND:Accurate prediction of treatment response and prognosis before surgery allows prompt therapy adjustment. This study aimed to evaluate the efficacy of computed tomography (CT) signs in predicting treatment response and survival for advanced esophageal squamous cell carcinoma patients who received preoperative...

journal_title：Annals of surgical oncology

authors： Zhang XY,Yan WP,Sun Y,Li XT,Chen Y,Fan MY,Wu Y,Liang Z,Xiong HC,Wang ZL,Sun YS,Chen KN

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Cancer antigen (CA) 125 tumor-associated antigen is a high molecular glycoprotein used for follow-up of epithelial ovarian cancer. The test is often requested as a differential diagnosis in patients with pleural or peritoneal fluid. This study analyzes the prevalence of CA-125 increases in a population of pa...

journal_title：Annals of surgical oncology

authors： Miralles C,Orea M,España P,Provencio M,Sánchez A,Cantos B,Cubedo R,Carcereny E,Bonilla F,Gea T

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Recently, it was reported that minimally invasive surgery (MIS) has a negative impact on early-stage cervical cancer (ECC) patient survival. At the same time, advantages of MIS regarding quality of life and low rate of intra- and postoperative complications are well known. Therefore, it is essential to selec...

journal_title：Annals of surgical oncology

authors： Pedone Anchora L,Turco LC,Bizzarri N,Capozzi VA,Lombisani A,Chiantera V,De Felice F,Gallotta V,Cosentino F,Fagotti A,Ferrandina G,Scambia G

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Matrix metalloproteinase 7 (MMP-7) is involved in invasion, metastasis, growth, and angiogenesis. The aim of this study is to assess the prognostic role of serum MMP-7 in curatively resected colorectal cancer (CRC). MATERIALS AND METHODS:Patients undergoing resection for CRC (n = 175) were recruited from Ju...

journal_title：Annals of surgical oncology

authors： Martínez-Fernandez A,García-Albeniz X,Pineda E,Visa L,Gallego R,Codony-Servat J,Augé JM,Longarón R,Gascón P,Lacy A,Castells A,Maurel J

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:For patients with rectal cancer, there is a greater risk of a positive radial margin or local tumor recurrence when an abdominoperineal versus low anterior resection is performed, or when tumors are in an anterior versus nonanterior location. In response, clinical leaders have encouraged perineal dissection ...

journal_title：Annals of surgical oncology

authors： Simunovic M,Pinthus J,Coates AJ,DeNardi F

更新日期：2012-03-01 00:00:00

abstract：INTRODUCTION:To identify melanoma patients at sufficiently low risk of nodal metastases who could avoid sentinel lymph node biopsy (SLNB), several statistical models have been proposed based upon patient/tumor characteristics, including logistic regression, classification trees, random forests, and support vector machi...

journal_title：Annals of surgical oncology

authors： Sabel MS,Rice JD,Griffith KA,Lowe L,Wong SL,Chang AE,Johnson TM,Taylor JM

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:We present an alternative access technique to facilitate preperitoneoscopic (extraperitoneal laparoscopic) approach for radical prostatectomy, herniorrhaphy, and other pelvic procedures. METHODS:A 0 degrees telescope was mounted into a Visiport Optical Trocar (Visiport), and via a periumbilical incision it ...

journal_title：Annals of surgical oncology

authors： Tai HC,Lai MK,Chueh SC,Chen SC,Hsieh MH,Yu HJ

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:CD8+ T cell-eliciting vaccines are being investigated in breast cancer patients. Preclinical data showed that trastuzumab increases the susceptibility of tumor cells to lysis by vaccine-generated CD8+ T cells, suggesting potential benefit of a combination immunotherapy strategy. The current trial was underta...

journal_title：Annals of surgical oncology

authors： Clifton GT,Litton JK,Arrington K,Ponniah S,Ibrahim NK,Gall V,Alatrash G,Peoples GE,Mittendorf EA

更新日期：2017-08-01 00:00:00

abstract：PURPOSE:The volume of surgical procedures performed by hospitals and surgeons has a strong influence on outcomes for a number of surgeries. We examined the influence of surgeon and hospital case volume on morbidity, mortality, and resource utilization for women with endometrial cancer undergoing laparoscopic hysterecto...

journal_title：Annals of surgical oncology

authors： Wright JD,Hershman DL,Burke WM,Lu YS,Neugut AI,Lewin SN,Herzog TJ

更新日期：2012-03-01 00:00:00

abstract：:The purpose of this study was to determine the outcome of surgery for patients with recurrent gastric or gastroesophageal cancer. We queried records from 7,459 patients who presented with gastric or gastroesophageal cancer to our institution from 1973 through 2005 to identify those for whom resection of recurrent dise...

journal_title：Annals of surgical oncology

authors： Badgwell B,Cormier JN,Xing Y,Yao J,Bose D,Krishnan S,Pisters P,Feig B,Mansfield P

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:International consensus criteria (ICC) have redefined borderline resectability for pancreatic ductal adenocarcinoma (PDAC) according to three dimensions: anatomical (BR-A), biological (BR-B), and conditional (BR-C). The present definition acknowledges that resectability is not just about the anatomic relatio...

journal_title：Annals of surgical oncology

authors： Anger F,Döring A,van Dam J,Lock JF,Klein I,Bittrich M,Germer CT,Wiegering A,Kunzmann V,van Eijck C,Löb S

更新日期：2020-09-12 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate outcomes after breast-conserving surgery (BCS) and intraoperative radiotherapy (IORT), and to identify risk factors associated with complications. MATERIALS/METHODS:We evaluated patients with early-stage breast cancer treated from January 1, 2011 to January 31, 2014 with...

journal_title：Annals of surgical oncology

authors： Rakhra S,Bethke K,Strauss J,Hayes JP,Hansen N,Khan SA,Helenowski I,Donnelly ED

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Although esophagectomy traditionally is recommended to perform within 8 weeks after neoadjuvant chemoradiotherapy (nCRT), data from neoadjuvantly treated rectal cancer patients demonstrate that delayed surgery ([8 weeks) can maximize the effect of CRT. Despite these promising data, investigators are concerne...

journal_title：Annals of surgical oncology

authors： Chiu CH,Chao YK,Chang HK,Tseng CK,Chan SC,Liu YH,Chen WH

更新日期：2013-12-01 00:00:00

abstract：INTRODUCTION:Radiation from medical imaging may induce cellular damage and increase the risk of cancer. While health care workers are restricted to an annual dose of 50 milliSieverts (mSv), the exposure to patients is not typically recorded. After breast-conservation therapy (BCT), patients are subjected to screening m...

journal_title：Annals of surgical oncology

authors： Marti JL,Dauer LT,Stempel M,Patil S,Kaplan JB,Montgomery LL

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Whether breast cancer surgeons are adequately trained, skilled, and experienced to provide breast cancer genetic assessment, testing, and counseling came under debate in September 2013 when a major third-party payer excluded nongenetics specialists from ordering such testing. A literature search having faile...

journal_title：Annals of surgical oncology

authors： Beitsch PD,Whitworth PW

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Isolated limb infusion (ILI) is a limb-preserving treatment for in-transit extremity melanoma. The benefit of resecting residual disease after ILI is unclear. METHODS:A multi-institutional experience was analyzed comparing patients who underwent ILI plus resection of residual disease (ILI + RES) versus ILI-...

journal_title：Annals of surgical oncology

authors： Wong J,Chen YA,Fisher KJ,Beasley GM,Tyler DS,Zager JS

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to investigate the diagnostic and prognostic value of circulating endothelial cell (CEC), a potential surrogate of tumor angiogenesis, in malignant pleural mesothelioma (MPM). METHODS:We prospectively evaluated CEC count in 4.0 mL of peripheral blood sampled from patients with ...

journal_title：Annals of surgical oncology

authors： Yoneda K,Tanaka F,Kondo N,Orui H,Hashimoto M,Takuwa T,Matsumoto S,Okumura Y,Tsubota N,Sato A,Tsujimura T,Kuribayashi K,Fukuoka K,Nakano T,Hasegawa S

更新日期：2012-12-01 00:00:00

abstract：:Isolated hepatic perfusion (IHP) is a proven approach for regional delivery of chemotherapy in patients with unresectable primary and metastatic tumors of the liver. Most trials of IHP have utilized melphalan as the active drug in the perfusate. We performed a phase I trial to evaluate the efficacy, safety, and maximu...

journal_title：Annals of surgical oncology

authors： Zeh HJ 3rd,Brown CK,Holtzman MP,Egorin MJ,Holleran JL,Potter DM,Bartlett DL

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:The anti-tumor effects of three mouse mammary tumors transfected to express interleukin (IL) 2 or 4 were evaluated. METHODS:Three immunologically different tumors were used: DA3, EMT6, and 410. All three cell lines were successfully transfected using high efficiency viral vectors. Wild-type or transfected t...

journal_title：Annals of surgical oncology

authors： Matory YL,Chen M,Goedegebuure PS,Eberlein TJ

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:The appropriate management of breast cancer risk in BRCA mutation carriers following ovarian cancer diagnosis remains unclear. We sought to determine the survival benefit and cost effectiveness of risk-reducing mastectomy (RRM) among women with BRCA1/2 mutations following stage II-IV ovarian cancer. DESIGN:...

journal_title：Annals of surgical oncology

authors： Gamble C,Havrilesky LJ,Myers ER,Chino JP,Hollenbeck S,Plichta JK,Kelly Marcom P,Shelley Hwang E,Kauff ND,Greenup RA

更新日期：2017-10-01 00:00:00

abstract：:There is increasing evidence regarding extracapsular lymph node involvement (LNI) as a prognostic factor for recurrence and poor prognosis in gastrointestinal malignancies. The aim of this study was to assess the prevalence and prognostic impact of LNI in patients with resected esophageal cancer, comparing adenocarcin...

journal_title：Annals of surgical oncology

authors： Metzger R,Drebber U,Baldus SE,Mönig SP,Hölscher AH,Bollschweiler E

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:The external branch of the superior laryngeal nerve (EBSLN) is at risk during thyroid surgery. Despite meticulous dissection and visualization, the EBSLN can be mistaken for other structures. The nerve integrity monitor (NIM) allows EBSLN confirmation with cricothyroid twitch on stimulation. AIMS:The aim of...

journal_title：Annals of surgical oncology

authors： Glover AR,Norlén O,Gundara JS,Morris M,Sidhu SB

更新日期：2015-01-01 00:00:00