Abstract:
:Random numbers are commonly used in many different fields, ranging from simulations in fundamental science to security applications. In some critical cases, as Bell's tests and cryptography, the random numbers are required to be both private and to be provided at an ultra-fast rate. However, practical generators are usually considered trusted, but their security can be compromised in case of imperfections or malicious external actions. In this work we introduce an efficient protocol which guarantees security and speed in the generation. We propose a source-device-independent protocol based on generic Positive Operator Valued Measurements and then we specialize the result to heterodyne measurements. Furthermore, we experimentally implemented the protocol, reaching a secure generation rate of 17.42 Gbit/s, without the need of an initial source of randomness. The security of the protocol has been proven for general attacks in the finite key scenario.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Avesani M,Marangon DG,Vallone G,Villoresi Pdoi
10.1038/s41467-018-07585-0subject
Has Abstractpub_date
2018-12-18 00:00:00pages
5365issue
1issn
2041-1723pii
10.1038/s41467-018-07585-0journal_volume
9pub_type
杂志文章abstract::Nonlinear spectroscopies are utilized extensively for selective measurements of chemical dynamics in the optical, infrared, and radio-frequency regimes. The development of these techniques for extreme ultraviolet (XUV) light sources facilitates measurements of electronic dynamics on attosecond timescales. Here, we elu...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-09317-4
更新日期:2019-03-27 00:00:00
abstract::Currently, solar-thermal energy storage within phase-change materials relies on adding high thermal-conductivity fillers to improve the thermal-diffusion-based charging rate, which often leads to limited enhancement of charging speed and sacrificed energy storage capacity. Here we report the exploration of a magnetica...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-01618-w
更新日期:2017-11-14 00:00:00
abstract::Cryo-electron microscopy can determine the structure of biological matter in vitrified liquids. However, structure alone is insufficient to understand the function of native and engineered biomolecules. So far, their mechanical properties have mainly been probed at room temperature using tens of pico-newton forces wit...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-08531-4
更新日期:2019-02-08 00:00:00
abstract::Glucose-induced insulin secretion is an essential function of pancreatic β-cells that is partially lost in individuals affected by Type 2 diabetes. This unique property of β-cells is acquired through a poorly understood postnatal maturation process involving major modifications in gene expression programs. Here we sho...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms9084
更新日期:2015-09-02 00:00:00
abstract::Synapse formation is triggered through trans-synaptic interaction between pairs of pre- and postsynaptic adhesion molecules, the specificity of which depends on splice inserts known as 'splice-insert signaling codes'. Receptor protein tyrosine phosphatase δ (PTPδ) can bidirectionally induce pre- and postsynaptic diffe...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms7926
更新日期:2015-04-24 00:00:00
abstract::Gene regulation and metabolism are two fundamental processes that coordinate the self-renewal and differentiation of neural precursor cells (NPCs) in the developing mammalian brain. However, little is known about how metabolic signals instruct gene expression to control NPC homeostasis. Here, we show that methylglyoxa...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-15941-2
更新日期:2020-04-24 00:00:00
abstract::Micro(mi)RNA-based post-transcriptional regulatory mechanisms have been broadly implicated in the assembly and modulation of synaptic connections required to shape neural circuits, however, relatively few specific miRNAs have been identified that control synapse formation. Using a conditional transgenic toolkit for co...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-14761-8
更新日期:2020-02-27 00:00:00
abstract::Generation of periodic patterns is fundamental to the differentiation of multiple tissues during development. How such patterns form robustly is still unclear. The Drosophila eye comprises ∼750 units, whose crystalline order is set during differentiation of the eye imaginal disc: an activation wave sweeping across the...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms10461
更新日期:2016-02-15 00:00:00
abstract::Because maintenance of non-scalable cellular components--membranes and chromosomes--requires an increasing fraction of energy as cell size decreases, miniaturization comes at a considerable energetic cost for a phytoplanktonic cell. Consequently, if eukaryotes can use their superior energetic resources to acquire nutr...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms4776
更新日期:2014-04-29 00:00:00
abstract::Extrachromosomal telomeric circles are commonly invoked as important players in telomere maintenance, but their origin has remained elusive. Using electron microscopy analysis on purified telomeres we show that, apart from known structures, telomeric repeats accumulate internal loops (i-loops) that occur in the proxim...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-19139-4
更新日期:2020-10-20 00:00:00
abstract::Identifying genes regulating the pace of epigenetic ageing represents a new frontier in genome-wide association studies (GWASs). Here using 1,796 brain samples from 1,163 individuals, we carry out a GWAS of two DNA methylation-based biomarkers of brain age: the epigenetic ageing rate and estimated proportion of neuron...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms15353
更新日期:2017-05-18 00:00:00
abstract::Iron chelators have been widely used to remove excess toxic iron from patients with secondary iron overload. However, small molecule-based iron chelators can cause adverse side effects such as infection, gastrointestinal bleeding, kidney failure, and liver fibrosis. Here we report renal clearable nanochelators for iro...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-13143-z
更新日期:2019-11-13 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Nature communications
pub_type: 已发布勘误
doi:10.1038/s41467-020-14901-0
更新日期:2020-02-24 00:00:00
abstract::Much controversy exists regarding the structural organization of the yeast centromeric nucleosome and the role of the nonhistone protein, Scm3, in its assembly and architecture. Here we show that the substitution of H3 with its centromeric variant Cse4 results in octameric nucleosomes that organize DNA in a left-hande...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms1320
更新日期:2011-01-01 00:00:00
abstract::Chemical clocks are often used as exciting classroom experiments, where an induction time is followed by rapidly changing colours that expose oscillating concentration patterns. This type of reaction belongs to a class of nonlinear chemical kinetics also linked to chaos, wave propagation and Turing patterns. Despite i...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms11832
更新日期:2016-06-10 00:00:00
abstract::Fire emissions generate air pollutants ozone (O3) and aerosols that influence the land carbon cycle. Surface O3 damages vegetation photosynthesis through stomatal uptake, while aerosols influence photosynthesis by increasing diffuse radiation. Here we combine several state-of-the-art models and multiple measurement da...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-07921-4
更新日期:2018-12-21 00:00:00
abstract::Carbon-based three-dimensional aerographite networks, built from interconnected hollow tubular tetrapods of multilayer graphene, are ultra-lightweight materials recently discovered and ideal for advanced multifunctional applications. In order to predict the bulk mechanical behaviour of networks it is very important to...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms14982
更新日期:2017-04-12 00:00:00
abstract::The quantum spin Hall (QSH) phase is an exotic phenomena in condensed-matter physics. Here we show that a minimal basis of three orbitals (s, px, py) is required to produce a QSH phase via nearest-neighbour hopping in a two-dimensional trigonal lattice. Tight-binding model analyses and calculations show that the QSH p...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms12746
更新日期:2016-09-07 00:00:00
abstract::Despite the success of current therapies for acute myocardial infarction (MI), many patients still develop adverse cardiac remodeling and heart failure. With the growing prevalence of heart failure, a new therapy is needed that can prevent remodeling and support tissue repair. Herein, we report on injectable recombina...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-12748-8
更新日期:2019-10-25 00:00:00
abstract::Blends of electron-donating and -accepting organic semiconductors are widely used as photoactive materials in next-generation solar cells and photodetectors. The yield of free charges in these systems is often determined by the separation of interfacial electron-hole pairs, which is expected to depend on the ability o...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms11944
更新日期:2016-06-21 00:00:00
abstract::DNA replication and repair enzyme Flap Endonuclease 1 (FEN1) is vital for genome integrity, and FEN1 mutations arise in multiple cancers. FEN1 precisely cleaves single-stranded (ss) 5'-flaps one nucleotide into duplex (ds) DNA. Yet, how FEN1 selects for but does not incise the ss 5'-flap was enigmatic. Here we combine...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms15855
更新日期:2017-06-27 00:00:00
abstract::Immunotherapy is emerging as a new pillar of cancer treatment with potential to cure. However, many patients still fail to respond to these therapies. Among the underlying factors, an immunosuppressive tumor microenvironment (TME) plays a major role. Here we show that monocyte-mediated gene delivery of IFNα inhibits l...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-05315-0
更新日期:2018-07-24 00:00:00
abstract::Niobium diselenide has long served as a prototype of two-dimensional charge ordering, believed to arise from an instability of the electronic structure analogous to the one-dimensional Peierls mechanism. Despite this, various anomalous properties have recently been identified experimentally, which cannot be explained ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms8034
更新日期:2015-05-07 00:00:00
abstract::Human gut microbiome is a promising target for managing type 2 diabetes (T2D). Measures altering gut microbiota like oral intake of probiotics or berberine (BBR), a bacteriostatic agent, merit metabolic homoeostasis. We hence conducted a randomized, double-blind, placebo-controlled trial with newly diagnosed T2D patie...
journal_title:Nature communications
pub_type: 杂志文章,随机对照试验
doi:10.1038/s41467-020-18414-8
更新日期:2020-10-06 00:00:00
abstract::The Johnson-Kendall-Roberts theory is the basis of modern contact mechanics. It describes how two deformable objects adhere together, driven by adhesion energy and opposed by elasticity. Here we characterize the indentation of glass particles into soft, silicone substrates using confocal microscopy. We show that, wher...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3728
更新日期:2013-01-01 00:00:00
abstract::Inversions are one type of structural variants linked to phenotypic differences and adaptation in multiple organisms. However, there is still very little information about polymorphic inversions in the human genome due to the difficulty of their detection. Here, we develop a new high-throughput genotyping method based...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-12173-x
更新日期:2019-09-17 00:00:00
abstract::Physical and electrochemical phenomena at the surfaces of transition metal oxides and their coupling to local functionality remains one of the enigmas of condensed matter physics. Understanding the emergent physical phenomena at surfaces requires the capability to probe the local composition, map order parameter field...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms5528
更新日期:2014-07-24 00:00:00
abstract::This corrects the article DOI: 10.1038/ncomms15732. ...
journal_title:Nature communications
pub_type: 杂志文章,已发布勘误
doi:10.1038/ncomms16183
更新日期:2018-03-12 00:00:00
abstract::Amyloid aggregation of α-synuclein (α-syn) is closely associated with Parkinson's disease (PD) and other synucleinopathies. Several single amino-acid mutations (e.g. E46K) of α-syn have been identified causative to the early onset of familial PD. Here, we report the cryo-EM structure of an α-syn fibril formed by N-ter...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-16386-3
更新日期:2020-05-26 00:00:00
abstract::In reducing the high operating temperatures (≥800 °C) of solid-oxide fuel cells, use of protonic ceramics as an alternative electrolyte material is attractive due to their high conductivity and low activation energy in a low-temperature regime (≤600 °C). Among many protonic ceramics, yttrium-doped barium zirconate has...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms14553
更新日期:2017-02-23 00:00:00