Transient late magnetic resonance imaging changes suggesting progression of brain stem glioma: implications for entry criteria for phase II trials.

Abstract:

:An 8-year-old boy was treated with irradiation (66 Gy) for a brain stem glioma. Five months after the completion of radiotherapy, magnetic resonance imaging demonstrated apparent tumor progression despite the patient's neurological improvement. The child continued to improve, with subsequent radiographic evidence of tumor regression, without additional therapeutic intervention. The evaluations of response and recurrence of brain tumors as well as entry criteria for Phase II studies are discussed.

journal_name

Neurosurgery

journal_title

Neurosurgery

authors

Longee DC,Friedman HS,Djang WT,Halperin E,Schold SC Jr,Oakes WJ

doi

10.1227/00006123-198808000-00024

subject

Has Abstract

pub_date

1988-08-01 00:00:00

pages

248-53

issue

2

eissn

0148-396X

issn

1524-4040

journal_volume

23

pub_type

临床试验,杂志文章
  • Craniocerebral injuries from dog bite in an infant.

    abstract::Animal bite is a common cause of craniofacial injuries in children. Whereas scalp lacerations from animal bites are often extensive and severe, only four instances of compound depressed skull fractures from animal bites have been reported. A case of a dog bite to the head of an infant is presented to point out the pot...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198110000-00015

    authors: Wilberger JE Jr,Pang D

    更新日期:1981-10-01 00:00:00

  • Electrophysiological aid in high thoracic sympathectomy for palmar hyperhidrosis.

    abstract::High upper thoracic sympathectomy using microsurgical techniques aided by electrical stimulation of the sympathetic chain is described. Use of the microscope facilitates identification and dissection of the sympathetic chain and minimizes the risk of pleural damage. Electrical stimulation of the sympathetic chain esta...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198903000-00026

    authors: Lindquist C,Fedorcsak I,Steig PE

    更新日期:1989-03-01 00:00:00

  • Hemianopia: a presenting feature of acute epidural hematomas.

    abstract::Visual field abnormalities were studied in a retrospective analysis of 199 patients with epidural hematomas. One hundred three patients had been alert enough at the time of hospital admission to have had their visual fields examined, but in only 27 patients were visual fields documented in the charts. Six of the 27 pa...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198208000-00007

    authors: Matwijecky C,Steinbok P

    更新日期:1982-08-01 00:00:00

  • Regulation of hexokinase in cultured gliomas.

    abstract::Positron emission computed tomographic (PECT) scanning studies have demonstrated that high grade gliomas exhibit increased 2-[18F]fluoro-2-deoxyglucose (18FDG) uptake compared to cerebral white matter and low grade gliomas. Hexokinase catalyzes the phosphorylation of glucose, as well as 18FDG and 2-deoxyglucose (2DG),...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198510000-00001

    authors: Graham JF,Cummins CJ,Smith BH,Kornblith PL

    更新日期:1985-10-01 00:00:00

  • Endovascular Management vs Intravenous Thrombolysis for Acute Stroke Secondary to Carotid Artery Dissection: Local Experience and Systematic Review.

    abstract:BACKGROUND:Little is known regarding the endovascular management of acute ischemic stroke (AIS) related to carotid artery dissection (CAD). OBJECTIVE:To report our interventional experience in AIS from CAD and to compare it with conservative treatment of CAD with intravenous thrombolysis (IVT) via systematic review. ...

    journal_title:Neurosurgery

    pub_type: 杂志文章,meta分析,评审

    doi:10.1227/NEU.0000000000001072

    authors: Haussen DC,Jadhav A,Jovin T,Grossberg JA,Grigoryan M,Nahab F,Obideen M,Lima A,Aghaebrahim A,Gulati D,Nogueira RG

    更新日期:2016-05-01 00:00:00

  • The Role of Stereotactic Radiosurgery in the Management of Brain Metastases From a Health-Economic Perspective: A Systematic Review.

    abstract:BACKGROUND:Stereotactic radiosurgery (SRS) is an effective option in the management of brain metastases, offering improved overall survival to whole-brain radiation therapy (WBRT). However, given the need for active surveillance and the possibility of repeated interventions for local/distant brain recurrences, the bala...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1093/neuros/nyaa075

    authors: Warsi NM,Karmur BS,Brar K,Moraes FY,Tsang DS,Laperriere N,Kondziolka D,Mansouri A

    更新日期:2020-09-01 00:00:00

  • Estimating energy expenditure in traumatic brain injury: comparison of indirect calorimetry with predictive formulas.

    abstract::A high degree of variability in energy expenditure has characterized the metabolic response to traumatic brain injury. A goal of parenteral or enteral repletion in this population is the precise estimation of caloric requirement to avoid complications associated with overfeeding and underfeeding. The first aim of this...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-199208000-00009

    authors: Sunderland PM,Heilbrun MP

    更新日期:1992-08-01 00:00:00

  • Iliac screw fixation using computer-assisted computer tomographic image guidance: technical note.

    abstract:BACKGROUND:Iliac screw fixation is a powerful tool used by spine surgeons to achieve fusion across the lumbosacral junction for a number of indications, including deformity, tumor, and pseudarthrosis. Complications associated with screw placement are related to blind trajectory selection and excessive soft tissue disse...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/NEU.0b013e318230517a

    authors: Shin JH,Hoh DJ,Kalfas IH

    更新日期:2012-03-01 00:00:00

  • Predictors of Poor Quality of Life 1 Year After Subarachnoid Hemorrhage.

    abstract:BACKGROUND:Risk factors for poor quality of life (QOL) after subarachnoid hemorrhage (SAH) remain poorly described. OBJECTIVE:To identify the frequency and predictors of poor QOL 1 year after SAH. METHODS:We studied 1-year QOL in a prospectively collected cohort of 1181 consecutively admitted SAH survivors between Ju...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/NEU.0000000000001042

    authors: Taufique Z,May T,Meyers E,Falo C,Mayer SA,Agarwal S,Park S,Connolly ES,Claassen J,Schmidt JM

    更新日期:2016-02-01 00:00:00

  • Intravenous Tissue Plasminogen Activator for Large Vessel Ischemic Stroke - Is There Still a Role?

    abstract::While the efficacy of Intravenous tissue plasminogen activator (tPA) is well established, its impact on large vessel occlusion (LVO) is controversial. Whether IV tPA should be bypassed in favor of endovascular thrombectomy (MT) will be addressed. Compelling evidence exists to suggest tPA administration might be bypass...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1093/neuros/nyz083

    authors: Sawyer RN

    更新日期:2019-07-01 00:00:00

  • The Use of Vancomycin Powder for Surgical Prophylaxis Following Craniotomy.

    abstract:BACKGROUND:Intrawound vancomycin powder has been studied extensively in spinal fusion surgeries and been found to reduce rates of surgical site infections (SSIs) significantly. Despite its success in spinal surgeries, topical vancomycin has not been extensively studied with respect to cranial neurosurgery. OBJECTIVE:T...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1093/neuros/nyw127

    authors: Ravikumar V,Ho AL,Pendhakar AV,Sussman ES,Kwong-Hon Chow K,Li G

    更新日期:2017-05-01 00:00:00

  • Intraoperative optical spectroscopy identifies infiltrating glioma margins with high sensitivity.

    abstract:OBJECTIVE:Adult gliomas have indistinct borders. As the ratio of neoplastic cells to normal cells becomes lower, the ability to detect these cells diminishes. We describe a device designed to augment intraoperative identification of both solid tumor and infiltrating tumor margins. METHODS:A novel, intraoperative, opti...

    journal_title:Neurosurgery

    pub_type: 临床试验,杂志文章

    doi:10.1227/01.neu.000176855.39826.2d

    authors: Toms SA,Lin WC,Weil RJ,Johnson MD,Jansen ED,Mahadevan-Jansen A

    更新日期:2005-10-01 00:00:00

  • Hydrocephalus-induced changes in the composition of cerebrospinal fluid.

    abstract::Studies reporting the composition of cerebrospinal fluid obtained from hydrocephalic humans have been critically reviewed. Hydrocephalus-induced alterations in the cerebrospinal fluid concentrations of neurotransmitters and peptide neuromodulators, products of glycolysis and nucleotide metabolism, neural cell-derived ...

    journal_title:Neurosurgery

    pub_type: 杂志文章,评审

    doi:10.1097/00006123-198909000-00016

    authors: Del Bigio MR

    更新日期:1989-09-01 00:00:00

  • Angioscopy-assisted aneurysm clipping.

    abstract:OBJECTIVE:To test the concept that endovascular angioscopy can assist surgical intracranial aneurysm clipping by providing an endoluminal view of the aneurysm-parent vessel complex. METHODS:A carotid bifurcation aneurysm was surgically created in a dog at the lingual artery origin. A balloon catheter was inflated prox...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-199909000-00032

    authors: Lanzino G,Miskolczi L,Guterman LR,Hopkins LN

    更新日期:1999-09-01 00:00:00

  • Cost-effectiveness of digital subtraction angiography in the setting of computed tomographic angiography negative subarachnoid hemorrhage.

    abstract:BACKGROUND:Recent studies have documented the high sensitivity of computed tomography angiography (CTA) in detecting a ruptured aneurysm in the presence of acute subarachnoid hemorrhage (SAH). The practice of digital subtraction angiography (DSA) when CTA does not reveal an aneurysm has thus been called into question. ...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/NEU.0b013e318282a578

    authors: Jethwa PR,Punia V,Patel TD,Duffis EJ,Gandhi CD,Prestigiacomo CJ

    更新日期:2013-04-01 00:00:00

  • Tumors of the jugular foramen: diagnosis and management.

    abstract:OBJECTIVE:Jugular foramen tumors are rare cranial base lesions that present diagnostic and management difficulties. With the availability of new diagnostic procedures these tumors have been more precisely studied and questions of whether, when, and how these lesions should be treated often arise. Data from 106 consecut...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.neu.0000163483.44754.47

    authors: Ramina R,Maniglia JJ,Fernandes YB,Paschoal JR,Pfeilsticker LN,Coelho Neto M

    更新日期:2005-07-01 00:00:00

  • Failure of intraoperative jugular bulb S-100B and neuron-specific enolase sampling to predict cognitive injury after carotid endarterectomy.

    abstract:OBJECTIVE:Cognitive decline occurs in 25% of patients after carotid endarterectomy (CEA). Elevated serum concentrations of S-100B and neuron-specific enolase (NSE) occur after stroke, and serum S-100B levels at 24 hours are associated with clinical outcome after both stroke and CEA. We hypothesized that we could detect...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.neu.0000093493.16850.11

    authors: Sahlein DH,Heyer EJ,Rampersad A,Winfree CJ,Solomon RA,Benvenisty AI,Quest DO,Du E,Connolly ES

    更新日期:2003-12-01 00:00:00

  • Expression of integrins in cerebral arteriovenous and cavernous malformations.

    abstract:OBJECTIVE:To assess and compare levels and patterns of expression for integrins alphavbeta1, alphavbeta3, and alphavbeta5 in arteriovenous malformations (AVMs) and cavernous malformations (CCMs) of the brain. MATERIALS AND METHODS:Specimens from 10 AVM and 10 CCM lesions were selected from 112 patients with AVMs and 9...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.neu.0000192174.55131.09

    authors: Seker A,Yildirim O,Kurtkaya O,Sav A,Günel M,Pamir MN,Kiliç T

    更新日期:2006-01-01 00:00:00

  • Techniques for the ventral correction of postsurgical cervical kyphotic deformity.

    abstract::Progressive kyphotic deformity of the cervical spine may be a late sequela of congenital cervical anomalies, degenerative disc disease, neoplasm, cervical trauma, and surgical procedures. Of these, postsurgical kyphosis is the most common and can occur after ventral and dorsal surgeries of the cervical spine. The purp...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.neu.0000144496.36844.7b

    authors: Stewart TJ,Steinmetz MP,Benzel EC

    更新日期:2005-01-01 00:00:00

  • Nerve Surgeons' Assessment of the Role of Eduard Pernkopf's Atlas of Topographic and Applied Human Anatomy in Surgical Practice.

    abstract:BACKGROUND:Pernkopf's atlas of Anatomy contains anatomical plates with detailed images of the peripheral nerves. Its use is controversial due to the author's association with the "Third Reich" and the potential depiction of victims of the Holocaust. The ethical implications of using this atlas for informing surgical pl...

    journal_title:Neurosurgery

    pub_type: 历史文章,杂志文章

    doi:10.1093/neuros/nyy159

    authors: Yee A,Coombs DM,Hildebrandt S,Seidelman WE,Coert JH,Mackinnon SE

    更新日期:2019-02-01 00:00:00

  • Computed tomography-based stereotactic third ventriculostomy: technical note.

    abstract::This report describes a computed tomography-based computer-assisted stereotactic technique for performing 3rd ventriculostomy. The procedure has been performed on seven patients with acquired obstructive hydrocephalus of various etiologies. None of these patients have yet required shunting. ...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198606000-00021

    authors: Kelly PJ,Goerss S,Kall BA,Kispert DB

    更新日期:1986-06-01 00:00:00

  • Clinical studies of de novo aneurysms.

    abstract::Although multiple cerebral aneurysms ae well recognized, a new aneurysm has only rarely been documented after successful treatment for an aneurysm elsewhere. In our consecutive series of 986 patients with intracranial saccular arterial aneurysm collected from 1975 to 1990, nine patients who had previously unverified (...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-199304000-00004

    authors: Sakaki T,Tominaga M,Miyamoto K,Tsunoda S,Hiasa Y

    更新日期:1993-04-01 00:00:00

  • Postsurgical Electrical Stimulation Enhances Recovery Following Surgery for Severe Cubital Tunnel Syndrome: A Double-Blind Randomized Controlled Trial.

    abstract:BACKGROUND:Patients with severe cubital tunnel syndrome often have poor functional recovery with conventional surgical treatment. Postsurgical electrical stimulation (PES) has been shown to enhance axonal regeneration in animal and human studies. OBJECTIVE:To determine if PES following surgery for severe cubital tunne...

    journal_title:Neurosurgery

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/neuros/nyz322

    authors: Power HA,Morhart MJ,Olson JL,Chan KM

    更新日期:2020-06-01 00:00:00

  • Trochlear nerve schwannomas occurring in patients without neurofibromatosis: case report and review of the literature.

    abstract:OBJECTIVE AND IMPORTANCE:Despite their predilection for sensory nerves, intracranial schwannomas have been reported in a number of mixed and purely motor cranial nerves, especially in association with Type 2 neurofibromatosis. We report the rare occurrence of a trochlear nerve schwannoma in a patient without neurofibro...

    journal_title:Neurosurgery

    pub_type: 杂志文章,评审

    doi:10.1097/00006123-199707000-00050

    authors: Santoreneos S,Hanieh A,Jorgensen RE

    更新日期:1997-07-01 00:00:00

  • The Harvard Neurosurgical Service at the Children's Hospital Boston and Brigham & Women's Hospital, 1912-2007.

    abstract::The Harvard Neurosurgical Service at Brigham and Women's Hospital and Children's Hospital Boston has a distinguished history, beginning in 1912 when Dr. Harvey Cushing became surgeon-in-chief at the Peter Bent Brigham Hospital. After Cushing left in 1932, the Children's Hospital had a dominant role, with the creation ...

    journal_title:Neurosurgery

    pub_type: 历史文章,杂志文章

    doi:10.1227/01.NEU.0000325262.13402.38

    authors: Shillito J,Black PM

    更新日期:2008-09-01 00:00:00

  • Extraskeletal myxoid chondrosarcoma of the falx.

    abstract::Intracranial cartilaginous tumors are unusual lesions, of which myxoid chondrosarcoma is the rarest. We describe this tumor arising from the falx in a 28-year-old woman treated at recurrence with a second operation and a radiation implant. The behavior of classic chondrosarcoma and mesenchymal chondrosarcoma is also r...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-199208000-00021

    authors: Salcman M,Scholtz H,Kristt D,Numaguchi Y

    更新日期:1992-08-01 00:00:00

  • Microsurgical anatomy of the dural arteries.

    abstract:OBJECTIVE:The objective was to examine the microsurgical anatomy basic to the microsurgical and endovascular management of lesions involving the dural arteries. METHODS:Adult cadaveric heads and skulls were examined using the magnification provided by the surgical microscope to define the origin, course, and distribut...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.neu.0000144823.94402.3d

    authors: Martins C,Yasuda A,Campero A,Ulm AJ,Tanriover N,Rhoton A Jr

    更新日期:2005-04-01 00:00:00

  • Pathophysiology of nonneoplastic obstruction of the foramen of Monro and progressive unilateral hydrocephalus.

    abstract::Our experience with progressive unilateral hydrocephalus in children and the pathophysiology of nonneoplastic obstruction of the foramen of Monro has been analyzed. The status of the foramen of Monro in either congenital or acquired progressive unilateral hydrocephalus was classified into the following four categories...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198512000-00003

    authors: Oi S,Matsumoto S

    更新日期:1985-12-01 00:00:00

  • The multiple tumor suppressor 1/cyclin-dependent kinase inhibitor 2 gene in human central nervous system primitive neuroectodermal tumor.

    abstract::The recently described multiple tumor suppressor 1/cyclin-dependent kinase inhibitor 2 (MTS1/CDKN2) gene, encoding the cyclin-dependent kinase 4 inhibitor p16, is mutated in a wide variety of tumor cell lines, including gliomas. To investigate the possible role of this gene in the genesis of the central nervous system...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-199505000-00013

    authors: Raffel C,Ueki K,Harsh GR 4th,Louis DN

    更新日期:1995-05-01 00:00:00

  • Randomized trials of neurosurgical interventions: a systematic appraisal.

    abstract:OBJECTIVE:To systematically appraise the study design and quality of reporting of randomized controlled trials (RCTs) on neurosurgical procedures and to identify potential defects and biases. METHODS:Randomized controlled trials with at least five patients comparing any neurosurgical procedure against another procedur...

    journal_title:Neurosurgery

    pub_type: 杂志文章,评审

    doi:10.1227/01.neu.0000126873.00845.a7

    authors: Vranos G,Tatsioni A,Polyzoidis K,Ioannidis JP

    更新日期:2004-07-01 00:00:00