Precision nutrition: hype or hope for public health interventions to reduce obesity?

Abstract:

:High-income countries are experiencing an obesity epidemic that follows a socioeconomic gradient, affecting groups of lower socioeconomic status disproportionately. Recent clinical findings have suggested new perspectives for the prevention and treatment of obesity, using personalized dietary approaches. Precision nutrition (PN), also called personalized nutrition, has been developed to deliver more preventive and practical dietary advice than 'one-size-fits-all' guidelines. With interventions becoming increasingly plausible at a large scale thanks to artificial intelligence and smartphone applications, some have begun to view PN as a novel way to deliver the right dietary intervention to the right population. We argue that large-scale PN, if taken alone, might be of limited interest from a public health perspective. Building on Geoffrey Rose's theory regarding the differences in individual and population causes of disease, we show that large-scale PN can only address some individual causes of obesity (causes of cases). This individual-centred approach is likely to have a small impact on the distribution of obesity at a population level because it ignores the population causes of obesity (causes of incidence). The latter are embedded in the populations' social, cultural, economic and political contexts that make environments obesogenic. Additionally, the most socially privileged groups in the population are the most likely to respond to large-scale PN interventions. This could have the undesirable effect of widening social inequalities in obesity. We caution public health actors that interventions based only on large-scale PN are unlikely, despite current expectations, to improve dietary intake or reduce obesity at a population level.

journal_name

Int J Epidemiol

authors

Chatelan A,Bochud M,Frohlich KL

doi

10.1093/ije/dyy274

subject

Has Abstract

pub_date

2019-04-01 00:00:00

pages

332-342

issue

2

eissn

0300-5771

issn

1464-3685

pii

5240939

journal_volume

48

pub_type

杂志文章
  • Association of height and violent criminality: results from a Swedish total population study.

    abstract:BACKGROUND:Violent criminality is at least moderately heritable, but the mechanisms behind this remain largely unexplained. Height, a highly heritable trait, may be involved but no study has estimated the effect of height on crime while simultaneously accounting for important demographic, biological and other heritable...

    journal_title:International journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/ije/dyt274

    authors: Beckley AL,Kuja-Halkola R,Lundholm L,Långström N,Frisell T

    更新日期:2014-06-01 00:00:00

  • Rapid decline in child mortality in a rural area of Senegal.

    abstract::Retrospective and prospective demographic and health data collected on the population of Mlomp (6352 people in 1985), a rural area of Senegal, show that the probability of dying before the age of 5 years declined from 350 to 81 deaths per hundred livebirths in the last 25 years. This decline is greater and faster than...

    journal_title:International journal of epidemiology

    pub_type: 历史文章,杂志文章

    doi:10.1093/ije/22.1.72

    authors: Pison G,Trape JF,Lefebvre M,Enel C

    更新日期:1993-02-01 00:00:00

  • Trends in occupational mortality among middle-aged men in Sweden 1961-1990.

    abstract:BACKGROUND:Many European countries have in recent decades reported growing socioeconomic differentials in mortality. While these trends have usually paralleled high unemployment and increasing income disparities, Sweden had low unemployment and narrowing income differences. This study describes trends, 1961-1990, in to...

    journal_title:International journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/ije/26.4.782

    authors: Diderichsen F,Hallqvist J

    更新日期:1997-08-01 00:00:00

  • Can synthetic controls improve causal inference in interrupted time series evaluations of public health interventions?

    abstract::Interrupted time series designs are a valuable quasi-experimental approach for evaluating public health interventions. Interrupted time series extends a single group pre-post comparison by using multiple time points to control for underlying trends. But history bias-confounding by unexpected events occurring at the sa...

    journal_title:International journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/ije/dyaa152

    authors: Degli Esposti M,Spreckelsen T,Gasparrini A,Wiebe DJ,Bonander C,Yakubovich AR,Humphreys DK

    更新日期:2021-01-23 00:00:00

  • Hypertension and sources of blood pressure variability among Mexican-Americans in Starr County, Texas.

    abstract::Previous investigations have established that the Mexican-American community of south Texas has a three- to five-fold elevated risk for non-insulin dependent diabetes mellitus when compared to the US population as a whole. In addition, evidence points to similarly increased risks of the related disorders, hypertension...

    journal_title:International journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/ije/14.2.231

    authors: Hanis CL,Ferrell RE,Schull WJ

    更新日期:1985-06-01 00:00:00

  • Registration of births, stillbirths and infant deaths in Jamaica.

    abstract:BACKGROUND:Vital statistics underestimate the prevalence of perinatal and infant deaths. This is particularly significant when these parameters affect eligibility for international assistance for newly emerging nations. OBJECTIVE:To determine the level of registration of livebirths, stillbirths and infant deaths in Ja...

    journal_title:International journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/ije/25.4.807

    authors: McCaw-Binns AM,Fox K,Foster-Williams KE,Ashley DE,Irons B

    更新日期:1996-08-01 00:00:00

  • Measles transmission in health facilities during outbreaks.

    abstract:BACKGROUND:Consultation waiting rooms and similar medical settings, either public or private, are places where children have higher probability of acquiring some infectious diseases, especially during outbreaks. METHODS:During a measles outbreak which occurred in Lisbon in 1989 a case-control study was carried out in ...

    journal_title:International journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/ije/23.4.843

    authors: Miranda AC,Falcão J,Dias JA,Nóbrega SD,Rebelo MJ,Pimenta ZP,Saúde MD

    更新日期:1994-08-01 00:00:00

  • What should be done about occupational accidents and diseases?

    abstract::This paper argues that the perspective of economics is valuable in assessing the desirability, purpose and effectiveness of public intervention to reduce occupational accidents and diseases and suggests that the concept of efficiency provides one (although not the only) important criterion by which to judge policy in ...

    journal_title:International journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/ije/12.1.77

    authors: Henderson J

    更新日期:1983-03-01 00:00:00

  • Alcohol consumption as a major risk factor for the rise in liver cancer mortality rates in Japanese men.

    abstract:BACKGROUND:Age-adjusted liver cancer mortality rates have been increasing for both men and women in Japan since 1970; however, increases in mortality rates in men are much greater than those in women. Hepatitis C virus infections and heavy alcohol consumption are considered to be the major risk factors of liver cancer ...

    journal_title:International journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/ije/28.1.30

    authors: Makimoto K,Higuchi S

    更新日期:1999-02-01 00:00:00

  • Trends in incidence of adenocarcinoma of the oesophagus and gastric cardia in ten European countries.

    abstract:BACKGROUND:In many western countries an increase in incidence of adenocarcinoma of the oesophagus and/or gastric cardia have been reported. The aim of this study was to describe and compare trends in incidence of adenocarcinoma of the oesophagus and gastric cardia in several areas of Europe, 1968-1995, using Eurocim (a...

    journal_title:International journal of epidemiology

    pub_type: 杂志文章,多中心研究

    doi:10.1093/ije/29.4.645

    authors: Botterweck AA,Schouten LJ,Volovics A,Dorant E,van Den Brandt PA

    更新日期:2000-08-01 00:00:00

  • Impact on sexually transmitted disease spread of increased condom use by young females, 1987-1992.

    abstract:BACKGROUND:Sexual behaviour data are crucial for understanding the spread of sexually transmitted diseases (STD). Over a period (1987-1992) in which the HIV epidemic increased public awareness of safe sexual practices, we describe predictors of condom use, changes in condom use over time, and the estimated effects of t...

    journal_title:International journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/ije/24.4.813

    authors: Stigum H,Magnus P,Veierød M,Bakketeig LS

    更新日期:1995-08-01 00:00:00

  • An age-period-cohort analysis of 50,875 AIDS cases among injecting drug users in Europe.

    abstract:BACKGROUND:The long average incubation time from HIV infection to AIDS makes it difficult to estimate recent HIV transmission from AIDS incidence data. Age-period-cohort (APC) analysis can separate out the effects of age, calendar time and birth cohort to provide a clearer picture of transmission trends. METHODS:AIDS ...

    journal_title:International journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/ije/28.6.1141

    authors: Houweling H,Wiessing LG,Hamers FF,Termorshuizen F,Gill ON,Sprenger MJ

    更新日期:1999-12-01 00:00:00

  • Child survival in Beirut during wartime: time trends and socio-religious differentials.

    abstract:BACKGROUND:Child mortality estimates in Beirut are presented for the late 1970s and the mid 1980s, and changes in socio-religious differentials of mortality across time are investigated. METHODS:Baseline information was obtained from maternity registries in Beirut in 1984 and 1991. Age of mother, number of children ev...

    journal_title:International journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/ije/26.1.110

    authors: Deeb M,Khlat M,Courbage Y

    更新日期:1997-02-01 00:00:00

  • Occupational risk factors for acute leukaemia: a case-control study.

    abstract::A case-control study has been performed for occupational risk factors of acute leukaemia, based on 185 cases more than 30 years old and 513 matched controls. There was a significant excess of polyvalent farming and electronic engineers among professions of cases, and, in addition of metal workers when considering the ...

    journal_title:International journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/ije/21.6.1063

    authors: Richardson S,Zittoun R,Bastuji-Garin S,Lasserre V,Guihenneuc C,Cadiou M,Viguie F,Laffont-Faust I

    更新日期:1992-12-01 00:00:00

  • Seroepidemiology of Helicobacter pylori infection in a population of Egyptian children.

    abstract:BACKGROUND:To describe the seroepidemiology of Helicobacter pylori infection in a population of Egyptian children under 3 years. METHODS:A cohort of children under 36 months, residing in Abu Homos, Egypt, were visited at home twice weekly. Information regarding the child's breastfeeding status was obtained, and period...

    journal_title:International journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/ije/29.5.928

    authors: Naficy AB,Frenck RW,Abu-Elyazeed R,Kim Y,Rao MR,Savarino SJ,Wierzba TF,Hall E,Clemens JD

    更新日期:2000-10-01 00:00:00

  • Lack of evidence on diets for obesity for children: a systematic review.

    abstract:BACKGROUND:The prevalence of obesity has increased rapidly in most developed countries in the last decades, and this rise is now spreading to developing countries. Childhood obesity is also increasing. The UK government has set a target to halt the rise in childhood obesity by 2010. Dietary recommendations are a centra...

    journal_title:International journal of epidemiology

    pub_type: 杂志文章,评审

    doi:10.1093/ije/dyl208

    authors: Gibson LJ,Peto J,Warren JM,dos Santos Silva I

    更新日期:2006-12-01 00:00:00

  • Trends in CHD mortality, morbidity and risk factor levels from 1960 to 1986: the Minnesota Heart Survey.

    abstract::The Minnesota Heart Survey (MHS) assessed population trends in coronary heart disease (CHD) mortality, morbidity and risk factor levels in the Twin Cities metropolitan area to explain the decline in CHD deaths. Age-adjusted CHD mortality rates declined in Twin Cities residents aged 30 to 74 from 1968 to 1986 by 52% in...

    journal_title:International journal of epidemiology

    pub_type: 杂志文章

    doi:

    authors: Burke GL,Sprafka JM,Folsom AR,Luepker RV,Norsted SW,Blackburn H

    更新日期:1989-01-01 00:00:00

  • The joint association of anxiety, depression and obesity with incident asthma in adults: the HUNT study.

    abstract:BACKGROUND:Anxiety or depression symptoms may increase the risk of developing asthma, and their interaction with obesity is not known. We aimed to assess the association of anxiety or depression symptoms and the joint association of these symptoms and obesity with incident asthma. METHODS:We conducted a prospective co...

    journal_title:International journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/ije/dyt151

    authors: Brumpton BM,Leivseth L,Romundstad PR,Langhammer A,Chen Y,Camargo CA Jr,Mai XM

    更新日期:2013-10-01 00:00:00

  • Usefulness of overnight pulse oximeter as the sleep assessment tool to assess the 6-year risk of road traffic collision: evidence from the Taiwan Bus Driver Cohort Study.

    abstract:Background:In order to support health service organizations in arranging a system for prevention of road traffic collisions (RTC), it is important to study the usefulness of sleep assessment tools. A cohort study was used to evaluate the effectiveness of subjective and objective sleep assessment tools to assess for the...

    journal_title:International journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/ije/dyw141

    authors: Wu WT,Tsai SS,Liao HY,Lin YJ,Lin MH,Wu TN,Shih TS,Liou SH

    更新日期:2017-02-01 00:00:00

  • Development and tracking of central patterns of subcutaneous fat in adolescence and adulthood: the Amsterdam Growth and Health Study.

    abstract:BACKGROUND:A central pattern of body fat is recognized as a risk indicator of cardiovascular diseases in adulthood. The development of this body fat pattern from childhood into adulthood however, remains to be explored. METHODS:The development of two trunk skinfolds (subscapular; supra-iliac), two extremity skinfolds ...

    journal_title:International journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/ije/25.6.1162

    authors: van Lenthe FJ,Kemper HC,van Mechelen W,Twisk JW

    更新日期:1996-12-01 00:00:00

  • Hospital admissions and mortality in the 15 years after a first-time hospital contact with an alcohol problem: a prospective cohort study using the entire Danish population.

    abstract:BACKGROUND:Potential benefits of preventing continued alcohol intake in individuals presenting at the hospital with an alcohol problem can be highlighted by studying their excess risk of subsequent morbidity and mortality. METHODS:All Danish residents with a first-time hospital contact with alcohol problems (intoxicat...

    journal_title:International journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/ije/dyz159

    authors: Askgaard G,Leon DA,Deleuran T,Tolstrup JS

    更新日期:2020-02-01 00:00:00

  • Headache, tinnitus and hearing loss in the international Cohort Study of Mobile Phone Use and Health (COSMOS) in Sweden and Finland.

    abstract:BACKGROUND:Mobile phone use and exposure to radiofrequency electromagnetic fields (RF-EMF) from it have been associated with symptoms in some studies, but the studies have shortcomings and their findings are inconsistent. We conducted a prospective cohort study to assess the association between amount of mobile phone u...

    journal_title:International journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/ije/dyz127

    authors: Auvinen A,Feychting M,Ahlbom A,Hillert L,Elliott P,Schüz J,Kromhout H,Toledano MB,Johansen C,Poulsen AH,Vermeulen R,Heinävaara S,Kojo K,Tettamanti G,COSMOS Study Group.

    更新日期:2019-10-01 00:00:00

  • Bayesian methods for instrumental variable analysis with genetic instruments ('Mendelian randomization'): example with urate transporter SLC2A9 as an instrumental variable for effect of urate levels on metabolic syndrome.

    abstract::The 'Mendelian randomization' approach uses genotype as an instrumental variable to distinguish between causal and non-causal explanations of biomarker-disease associations. Classical methods for instrumental variable analysis are limited to linear or probit models without latent variables or missing data, rely on asy...

    journal_title:International journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/ije/dyp397

    authors: McKeigue PM,Campbell H,Wild S,Vitart V,Hayward C,Rudan I,Wright AF,Wilson JF

    更新日期:2010-06-01 00:00:00

  • A person to person hepatitis A outbreak.

    abstract::A person to person outbreak of hepatitis A is described: 90 cases of hepatitis A occurred in a small town in Calabria, southern Italy; all cases were under 18 years of age with the highest age-specific incidence rate in the 6-10 year age group. Transmission was identified by tracing close contacts with other incubatin...

    journal_title:International journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/ije/15.1.108

    authors: Greco D,De Giacomi G,Piersante GP,Bibby L,Nicastro M,Cavalcanti P

    更新日期:1986-03-01 00:00:00

  • Effects of body fat and its development over a ten-year period on glucose tolerance in euglycaemic men: the Zutphen Study.

    abstract::The relationship between body fat and different aspects of glucose tolerance was examined within the Zutphen Study. In 1970 an oral glucose tolerance test (OGTT) was carried out in 404 non-diabetic men aged 50-70. None of the subjects could be classified as having impaired glucose tolerance. Body mass index (BMI), sub...

    journal_title:International journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/ije/18.2.368

    authors: Feskens EJ,Kromhout D

    更新日期:1989-06-01 00:00:00

  • Male microchimerism and survival among women.

    abstract:BACKGROUND:During pregnancy, woman and fetus exchange small quantities of cells, and their persistence at later times is termed microchimerism. Microchimerism is known to substantially impact on women's later health. This study examined the survival of women according to male microchimerism status. METHODS:Male microc...

    journal_title:International journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/ije/dyt230

    authors: Kamper-Jørgensen M,Hjalgrim H,Andersen AM,Gadi VK,Tjønneland A

    更新日期:2014-02-01 00:00:00

  • Probabilistic record linkage and a method to calculate the positive predictive value.

    abstract:BACKGROUND:Computerized record linkage is commonly used in cohort studies to ascertain the study outcome, and as such its accuracy classifying the outcome can be described using the standard epidemiological terms of sensitivity and positive predictive value (PPV). METHOD:We describe a 'duplicate method' to calculate t...

    journal_title:International journal of epidemiology

    pub_type: 杂志文章,评审

    doi:10.1093/ije/31.6.1246

    authors: Blakely T,Salmond C

    更新日期:2002-12-01 00:00:00

  • Is Trichomonas vaginalis a cause of cervical neoplasia? Results from a combined analysis of 24 studies.

    abstract:BACKGROUND:We conducted this combined analysis of available data from studies with information on this issue to clarify the association between Trichomonas vaginalis infection and cervical neoplasia. METHODS:We performed MEDLINE searches (1966-1993) using the key words and phrases 'trichomonas vaginitis' and 'neoplasm...

    journal_title:International journal of epidemiology

    pub_type: 杂志文章,meta分析

    doi:10.1093/ije/23.4.682

    authors: Zhang ZF,Begg CB

    更新日期:1994-08-01 00:00:00

  • Association of HIV and ART with cardiometabolic traits in sub-Saharan Africa: a systematic review and meta-analysis.

    abstract:BACKGROUND:Sub-Saharan Africa (SSA) has the highest burden of HIV in the world and a rising prevalence of cardiometabolic disease; however, the interrelationship between HIV, antiretroviral therapy (ART) and cardiometabolic traits is not well described in SSA populations. METHODS:We conducted a systematic review and m...

    journal_title:International journal of epidemiology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1093/ije/dyt198

    authors: Dillon DG,Gurdasani D,Riha J,Ekoru K,Asiki G,Mayanja BN,Levitt NS,Crowther NJ,Nyirenda M,Njelekela M,Ramaiya K,Nyan O,Adewole OO,Anastos K,Azzoni L,Boom WH,Compostella C,Dave JA,Dawood H,Erikstrup C,Fourie CM,Fr

    更新日期:2013-12-01 00:00:00

  • Fatness biases the use of estimated leg length as an epidemiological marker for adults in the NHANES III sample.

    abstract:BACKGROUND:We analyse the NHANES III sample to assess the suitability of measured stature and sitting height to estimate leg length (tibia + femur) and predict fatness. High rates of overweight in the United States population may lead to greater gluteo-femoral fat mass which will increase sitting height and artificiall...

    journal_title:International journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/ije/dym254

    authors: Bogin B,Varela-Silva MI

    更新日期:2008-02-01 00:00:00