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Ecdysis triggering hormone receptors regulate male courtship behavior via antennal lobe interneurons in Drosophila.

Abstract：

:Ecdysis triggering hormone receptors (ETHR) regulate the behavioral sequence necessary for cuticle shedding. Recent reports have documented functions for ETHR signaling in adult Drosophila melanogaster. In this study, we report that ETHR silencing in local interneurons of the antennal lobes and fruitless neurons leads to sharply increased rates of male-male courtship. RNAseq analysis of ETHR knockdown flies reveals differential expression of genes involved in axon guidance, courtship behavior and chemosensory functions. Our findings indicate an important role for ETHR in regulation of Drosophila courtship behavior through chemosensory processing in the antennal lobe.

journal_name

Gen Comp Endocrinol

journal_title

General and comparative endocrinology

authors

Deshpande SA,Meiselman M,Hice RH,Arensburger P,Rivera-Perez C,Kim DH,Croft RL,Noriega FG,Adams ME

doi

10.1016/j.ygcen.2018.12.003

subject

Has Abstract

pub_date

2019-07-01 00:00:00

pages

79-88

eissn

0016-6480

issn

1095-6840

pii

S0016-6480(18)30323-X

journal_volume

278

pub_type

杂志文章

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