Nationwide registry of sepsis patients in Japan focused on disseminated intravascular coagulation 2011-2013.

Abstract:

:Sepsis is a syndrome with physiologic, pathologic, and biochemical abnormalities induced by infection. Sepsis can induce the dysregulation of systemic coagulation and fibrinolytic systems, resulting in disseminated intravascular coagulation (DIC), which is associated with a high mortality rate. Although there is no international consensus on available treatments for sepsis-induced DIC, DIC diagnosis and treatment are commonly performed in Japanese clinical settings. Therefore, clinical data related to sepsis-induced DIC diagnosis and treatment can be obtained from Japanese clinical settings. We performed a retrospective nationwide observational study (Japan Septic Disseminated Intravascular Coagulation [J-SEPTIC DIC] study) to collect data regarding characteristics of sepsis patients in Japan, with a focus on coagulofibrinolytic dysregulation and DIC treatment received by each patient. The J-SEPTIC DIC study collected information for a total of 3,195 patients with severe sepsis and septic shock and is the largest data set in Japan on DIC diagnosis and treatment in clinical settings.

journal_name

Sci Data

journal_title

Scientific data

authors

Hayakawa M,Yamakawa K,Saito S,Uchino S,Kudo D,Iizuka Y,Sanui M,Takimoto K,Mayumi T

doi

10.1038/sdata.2018.243

subject

Has Abstract

pub_date

2018-12-11 00:00:00

pages

180243

issn

2052-4463

pii

sdata2018243

journal_volume

5

pub_type

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