Analysis of genome-wide variants through bulked segregant RNA sequencing reveals a major gene for resistance to Plasmodiophora brassicae in Brassica oleracea.

abstract：:Soil fauna are critical for ecosystem function and sensitive to the changes of soil fertility. The effects of fertilization on soil fauna communities, however, remain poorly understood. We examined the effects of fertilization form and quantity on the abundance, diversity and composition of soil fauna across an age-se...

journal_title：Scientific reports

authors： Wang S,Chen HY,Tan Y,Fan H,Ruan H

更新日期：2016-02-09 00:00:00

abstract：:Muscle wasting and atrophy are regulated by multiple molecular processes, including mRNA processing. Reduced levels of the polyadenylation binding protein nucleus 1 (PABPN1), a multifactorial regulator of mRNA processing, cause muscle atrophy. A proteomic study in muscles with reduced PABPN1 levels suggested dysregula...

journal_title：Scientific reports

authors： Olie CS,van der Wal E,Domagoj C,Maton L,de Greef JC,Lin IH,Chen YF,Kareem E,Penninger JM,Kessler BM,Raz V

更新日期：2020-10-19 00:00:00

abstract：:Dynamic Nuclear Polarization (DNP) has been introduced to overcome the sensitivity limitations of nuclear magnetic resonance (NMR) spectroscopy also of supported lipid bilayers. When investigated by solid-state NMR techniques the approach typically involves doping the samples with biradicals and their investigation at...

journal_title：Scientific reports

authors： Salnikov ES,Aisenbrey C,Aussenac F,Ouari O,Sarrouj H,Reiter C,Tordo P,Engelke F,Bechinger B

更新日期：2016-02-15 00:00:00

abstract：:In this work, four water-soluble polythiophene derivatives (PT, PT-DDA, PT-ADA, and PT-ADA-PPR) with different pendant moieties were synthesized via oxidative copolymerization by FeCl3. By increasing the hydrophobic ability of side chain moieties, there is a gradually blue shift for the maximum absorption wavelength a...

journal_title：Scientific reports

authors： Wang F,Li M,Wang B,Zhang J,Cheng Y,Liu L,Lv F,Wang S

更新日期：2015-01-05 00:00:00

abstract：:Lower corrected calcium (cCa) levels are associated with a better prognosis among incident dialysis patients. However, cCa frequently overestimates ionized calcium (iCa) levels. The prognostic importance of the true calcium status defined by iCa remains to be revealed. We conducted a retrospective cohort study of inci...

journal_title：Scientific reports

authors： Yamaguchi S,Hamano T,Doi Y,Oka T,Kajimoto S,Kubota K,Yasuda S,Shimada K,Matsumoto A,Hashimoto N,Sakaguchi Y,Matsui I,Isaka Y

更新日期：2020-03-10 00:00:00

abstract：:The ejection of internal organs, i.e., evisceration, is a well-known phenomenon in sea-cucumbers. We report the ability of a member of the Chordate phyla, the tropical ascidian Polycarpa mytiligera, to eviscerate and regenerate its gut within 12 days, and to rebuild its branchial sac within 19 days. Evisceration occur...

journal_title：Scientific reports

authors： Shenkar N,Gordon T

更新日期：2015-04-16 00:00:00

abstract：:GLP-1 receptor agonists (GLP-1RA) and SGLT2 inhibitors (SGLT2i) have been associated with improved glycemic control, body weight loss and favorable changes in cardiovascular risk factors and outcomes. We conducted a systematic review and meta-analysis to evaluate the effects of the addition of GLP-1RA to SGLT2i in pat...

journal_title：Scientific reports

authors： Castellana M,Cignarelli A,Brescia F,Perrini S,Natalicchio A,Laviola L,Giorgino F

更新日期：2019-12-18 00:00:00

abstract：:Drug-resistant bacteria represent a significant global threat. Given the dearth of new antibiotics, host-directed therapies (HDTs) are especially desirable. As IFN-gamma (IFNγ) plays a central role in host resistance to intracellular bacteria, including Mycobacterium tuberculosis, we searched for small molecules to au...

journal_title：Scientific reports

authors： Bhattacharya B,Chatterjee S,Devine WG,Kobzik L,Beeler AB,Porco JA Jr,Kramnik I

更新日期：2016-04-18 00:00:00

abstract：:Development of quantitative analysis software has enabled application of several standardised uptake values (SUV) for bone analysis in single photon emission computed tomography (SPECT). The present retrospective study aimed to develop a reliable method of monitoring bone inflammatory activity in antiresorptive agent-...

journal_title：Scientific reports

authors： Hata H,Kitao T,Sato J,Asaka T,Ohga N,Imamachi K,Hirata K,Shiga T,Yamazaki Y,Kitagawa Y

更新日期：2020-07-09 00:00:00

abstract：:Förster Resonance Energy Transfer (FRET) allows for the visualization of nanometer-scale distances and distance changes. This sensitivity is regularly achieved in single-molecule experiments in vitro but is still challenging in biological materials. Despite many efforts, quantitative FRET in living samples is either r...

journal_title：Scientific reports

authors： Coullomb A,Bidan CM,Qian C,Wehnekamp F,Oddou C,Albigès-Rizo C,Lamb DC,Dupont A

更新日期：2020-04-16 00:00:00

abstract：:Ionizing radiation (IR)-induced intestinal damage is characterized by a loss of intestinal crypt cells, intestinal barrier disruption and translocation of intestinal microflora resulting in sepsis-mediated lethality. We have shown that mice lacking C/EBPδ display IR-induced intestinal and hematopoietic injury and leth...

journal_title：Scientific reports

authors： Banerjee S,Fu Q,Shah SK,Melnyk SB,Sterneck E,Hauer-Jensen M,Pawar SA

更新日期：2019-09-27 00:00:00

abstract：:Traditional diagnostic detection of chronic wasting disease (CWD) relies on immunodetection of misfolded CWD prion protein (PrP(CWD)) by western blotting, ELISA, or immunohistochemistry (IHC). These techniques require separate sample collections (frozen and fixed) which may result in discrepancies due to variation in ...

journal_title：Scientific reports

authors： Hoover CE,Davenport KA,Henderson DM,Pulscher LA,Mathiason CK,Zabel MD,Hoover EA

更新日期：2016-05-09 00:00:00

abstract：:Although recovery following a stroke is limited, undamaged neurons under the right conditions can establish new connections and take on-board lost functions. Sonic hedgehog (Shh) signaling is integral for developmental axon growth, but its role after injury has not been fully examined. To investigate the effects of Sh...

journal_title：Scientific reports

authors： Berretta A,Gowing EK,Jasoni CL,Clarkson AN

更新日期：2016-02-23 00:00:00

abstract：:Alcoholic liver disease (ALD) causes significant morbidity and mortality, and pharmacological treatment options are limited. In this study, we evaluated the PCSK9 inhibitor alirocumab, a monoclonal antibody that robustly reduces low-density lipoprotein cholesterol (LDL-C), for the treatment of ALD using a rat model of...

journal_title：Scientific reports

authors： Lee JS,Mukhopadhyay P,Matyas C,Trojnar E,Paloczi J,Yang YR,Blank BA,Savage C,Sorokin AV,Mehta NN,Vendruscolo JCM,Koob GF,Vendruscolo LF,Pacher P,Lohoff FW

更新日期：2019-11-20 00:00:00

abstract：:Honeybees (Apis mellifera L.), which unquestionably play an economically important role in pollination and agricultural production, are at risk of decline. To study changes in gene expression in insects upon exposure to pesticides or other external stimuli, appropriate reference genes are required for data normalizati...

journal_title：Scientific reports

authors： Wieczorek P,Frąckowiak P,Obrępalska-Stęplowska A

更新日期：2020-09-30 00:00:00

abstract：:It is generally believed that anthropogenic aerosols cool the atmosphere; therefore, they offset the global warming resulting from greenhouse gases to some extent. Reduction in sulphate, a primary anthropogenic aerosol, is necessary for mitigating air pollution, which causes atmospheric warming. Here, the changes in t...

journal_title：Scientific reports

authors： Takemura T

更新日期：2020-12-10 00:00:00

abstract：:Tumor clonal heterogeneity drives treatment resistance. But robust models are lacking that permit eavesdropping on the basic interaction network of tumor clones. We developed an in vitro, functional model of clonal cooperation using U87MG glioblastoma cells, which isolates fundamental clonal interactions. In this mode...

journal_title：Scientific reports

authors： Davis JB,Krishna SS,Abi Jomaa R,Duong CT,Espina V,Liotta LA,Mueller C

更新日期：2019-11-22 00:00:00

abstract：:Modern society characterized by a 24/7 lifestyle leads to misalignment between environmental cycles and endogenous circadian rhythms. Persisting circadian misalignment leads to deleterious effects on health and healthspan. However, the underlying mechanism remains not fully understood. Here, we subjected adult, wild-t...

journal_title：Scientific reports

authors： Inokawa H,Umemura Y,Shimba A,Kawakami E,Koike N,Tsuchiya Y,Ohashi M,Minami Y,Cui G,Asahi T,Ono R,Sasawaki Y,Konishi E,Yoo SH,Chen Z,Teramukai S,Ikuta K,Yagita K

更新日期：2020-02-13 00:00:00

abstract：:Electronic cigarettes (ECs) are nicotine delivery devices that are proposed as tobacco harm reduction products to smokers. Nicotine delivery from ECs is potentially important in their efficacy as smoking substitutes. Herein, nicotine delivery from using a new-generation EC device (variable-wattage, set at 9 W) was eva...

journal_title：Scientific reports

authors： Farsalinos KE,Spyrou A,Stefopoulos C,Tsimopoulou K,Kourkoveli P,Tsiapras D,Kyrzopoulos S,Poulas K,Voudris V

更新日期：2015-06-17 00:00:00

abstract：:Life-history theory predicts that current behaviour affects future reproduction, implying that animals should optimise their escape strategies to reflect fitness costs and benefits of premature escape. Both costs and benefits of escape may change temporally with important consequences for the evolution of escape strat...

journal_title：Scientific reports

authors： Mikula P,Díaz M,Albrecht T,Jokimäki J,Kaisanlahti-Jokimäki ML,Kroitero G,Møller AP,Tryjanowski P,Yosef R,Hromada M

更新日期：2018-09-18 00:00:00

abstract：:It is challenging to create artificial catalysts that approach enzymes with regard to catalytic efficiency and selectivity. The enantioselective catalysis ranks the privileged characteristic of enzymatic transformations. Here, we report two pyridine-linked bis(β-cyclodextrin) (bisCD) copper(II) complexes that enantios...

journal_title：Scientific reports

authors： Xue SS,Zhao M,Ke ZF,Cheng BC,Su H,Cao Q,Cao ZK,Wang J,Ji LN,Mao ZW

更新日期：2016-02-26 00:00:00

abstract：:Rotator cuff tears are common and are associated with shoulder pain, disability, and dysfunction. Previous studies that have reported different arthroscopic techniques are controversial. A network meta-analysis with indirect and direct evidence was performed to compare the effectiveness of arthroscopic techniques for ...

journal_title：Scientific reports

authors： Xu B,Chen L,Zou J,Gu Y,Hao L,Peng K

更新日期：2019-03-11 00:00:00

abstract：:Prenatal skeletal muscle development genetically determines postnatal muscle characteristics such as growth and meat quality in pigs. However, the molecular mechanisms underlying prenatal skeletal muscle development remain unclear. Here, we performed the first genome-wide analysis of chimeric RNAs, single nuclear poly...

journal_title：Scientific reports

authors： Yang Y,Tang Z,Fan X,Xu K,Mu Y,Zhou R,Li K

更新日期：2016-06-29 00:00:00

abstract：:Early ontogenetic periods and postnatal maturation in organisms are sex-specifically sensitive to hypothalamic-pituitary-adrenal (HPA)-axis activities, related glucocorticoid secretions, and their effects on energy balance and homeostasis. Dietary polyunsaturated (PUFAs) and saturated (SFAs) fatty acids potentially pl...

journal_title：Scientific reports

authors： Nemeth M,Millesi E,Schuster D,Quint R,Wagner KH,Wallner B

更新日期：2018-01-11 00:00:00

abstract：:The prevalence of type 2 diabetes (T2D) has increased dramatically in Middle Eastern populations that represent the largest non-European immigrant group in Sweden today. As proneurotensin predicts T2D, the aim of this study was to investigate differences in proneurotensin levels across populations of Middle Eastern an...

journal_title：Scientific reports

authors： Fawad A,Nilsson PM,Struck J,Bergmann A,Melander O,Bennet L

更新日期：2019-09-20 00:00:00

abstract：:HMG domain transcription factor, Sox2, is a critical gene for the development of cochlear hair cells, the receptor cells for hearing, but this has been ascribed to expansion of the progenitors that become hair cells. Here, we show that Sox2 activated Atoh1, a transcription factor important for hair cell differentiatio...

journal_title：Scientific reports

authors： Kempfle JS,Turban JL,Edge AS

更新日期：2016-03-18 00:00:00

abstract：:Exfoliated monolayer graphene flakes were embedded in a polymer matrix and loaded under axial compression. By monitoring the shifts of the 2D Raman phonons of rectangular flakes of various sizes under load, the critical strain to failure was determined. Prior to loading care was taken for the examined area of the flak...

journal_title：Scientific reports

authors： Androulidakis C,Koukaras EN,Frank O,Tsoukleri G,Sfyris D,Parthenios J,Pugno N,Papagelis K,Novoselov KS,Galiotis C

更新日期：2014-06-12 00:00:00

abstract：:Traditional radiomics models mainly rely on explicitly-designed handcrafted features from medical images. This paper aimed to investigate if deep features extracted via transfer learning can generate radiomics signatures for prediction of overall survival (OS) in patients with Glioblastoma Multiforme (GBM). This study...

journal_title：Scientific reports

authors： Lao J,Chen Y,Li ZC,Li Q,Zhang J,Liu J,Zhai G

更新日期：2017-09-04 00:00:00

abstract：:Surface-enhanced Raman spectroscopy (SERS) has attracted a lot of attention in molecular sensing because of the remarkable ability of plasmonic metal nanostructures to enhance the weak Raman scattering process. On the other hand, coherent vibrational spectroscopy triggered by impulsive excitation using ultrafast laser...

journal_title：Scientific reports

authors： Du J,Harra J,Virkki M,Mäkelä JM,Leng Y,Kauranen M,Kobayashi T

更新日期：2016-11-04 00:00:00

abstract：:Polarimetric imaging has proved its value in medical diagnostics, bionics, remote sensing, astronomy, and in many other wide fields. Pixel-level solid monolithically integrated polarimetric imaging photo-detectors are the trend for infrared polarimetric imaging devices. For better polarimetric imaging performance the ...

journal_title：Scientific reports

authors： Li Q,Li Z,Li N,Chen X,Chen P,Shen X,Lu W

更新日期：2014-09-11 00:00:00