Coagulation Pathways, Hemostasis, and Thrombosis in Liver Failure.

abstract：:Hyperoxia, or excess oxygen supplementation, prevails in the intensive care unit (ICU) without a beneficial effect and, in some instances, may cause harm. Recent interest and surge in clinical studies in mechanically ventilated critically ill patients has brought this to the attention of clinicians and researchers. Hy...

journal_title：Seminars in respiratory and critical care medicine

authors： Pannu SR

更新日期：2016-02-01 00:00:00

abstract：:In heart failure (HF), pleural effusion results from increased interstitial fluid in the lung due to elevated pulmonary capillary pressure. Rarely, pleural effusions may occur in association with isolated right HF. HF-associated effusions are typically bilateral, but if unilateral, they are more commonly seen on the r...

journal_title：Seminars in respiratory and critical care medicine

authors： Porcel JM

更新日期：2010-12-01 00:00:00

abstract：:Multiorgan dysfunction syndrome represents a continuum of cumulative organ dysfunction from very mildly altered function to total and, rarely, irreversible organ failure and is the major cause of death in the intensive care unit (ICU). The terms multiple organ failure syndrome (MOFS), multiple organ system failure (MO...

journal_title：Seminars in respiratory and critical care medicine

authors： Ferreira AM,Sakr Y

更新日期：2011-10-01 00:00:00

abstract：:Chronic pulmonary sepsis is the predominant cause of morbidity for patients with cystic fibrosis (CF) and non-CF bronchiectasis. Previously it was thought that respiratory infection in these patients was mostly limited to a very small number of typical pathogens; however, in recent years there have been increasing rep...

journal_title：Seminars in respiratory and critical care medicine

authors： Green H,Jones AM

更新日期：2015-04-01 00:00:00

abstract：:Assisted mechanical ventilation (MV) may be a favorable alternative to controlled MV at the early phase of acute respiratory distress syndrome (ARDS), since it requires less sedation, no paralysis and is associated with less hemodynamic deterioration, better distal organ perfusion, and lung protection, thus reducing t...

journal_title：Seminars in respiratory and critical care medicine

authors： Saddy F,Sutherasan Y,Rocco PR,Pelosi P

更新日期：2014-08-01 00:00:00

abstract：:Sjögren syndrome (SS) is a chronic autoimmune disease characterized by lymphocytic inflammation of exocrine glands and a variety of extraglandular sites. Lung involvement as defined by symptoms and either pulmonary function testing or radiographic abnormalities occurs in approximately 10 to 20% of patients. Subclinica...

journal_title：Seminars in respiratory and critical care medicine

authors： Kreider M,Highland K

更新日期：2014-04-01 00:00:00

abstract：:Nonneoplastic pulmonary lymphoid disorders consist of a complex spectrum of diseases for pathologists and pulmonologists alike. Advances in our understanding of these disorders in recent years have led to revisions in the classification scheme. This review summarizes the clinicoradiological and pathological features o...

journal_title：Seminars in respiratory and critical care medicine

authors： Tian X,Yi ES,Ryu JH

更新日期：2012-10-01 00:00:00

abstract：:Pulmonary rehabilitation is a standard of care for patients with chronic lung disease. Through appropriate patient selection and assessment, exercise training, educational and psychosocial intervention, nutritional counseling, and breathing retraining, many benefits (e.g., reduction in level of dyspnea, improvement in...

journal_title：Seminars in respiratory and critical care medicine

authors： Carlin BW

更新日期：2009-12-01 00:00:00

abstract：:Cystic fibrosis (CF) is now more common in adults than children in countries with well-developed health care systems. The number of adults continues to increase and will further increase if the new cystic fibrosis transmembrane conductance regulator (CFTR) modulators are disease modifying. Most of the complex morbidit...

journal_title：Seminars in respiratory and critical care medicine

authors： Elborn JS

更新日期：2019-12-01 00:00:00

abstract：:Patients with cystic fibrosis (CF) exhibit significant variability in the course and severity of the disease, and this variability is best interpreted in the context of an interaction between genetic and nongenetic determinants. While a small number of patients with "mild" mutations in the CF transmembrane conductance...

journal_title：Seminars in respiratory and critical care medicine

authors： Schechter MS

更新日期：2003-12-01 00:00:00

abstract：:Mortality from the adult respiratory distress syndrome (ARDS) and the infant respiratory distress syndrome remains high despite numerous interventions and modalities. Perfluorocarbons (PFC) are inert liquids that can dissolve large amounts of oxygen and carbon dioxide and can be used as respiratory media. Partial liqu...

journal_title：Seminars in respiratory and critical care medicine

authors： Hadjiliadis D

更新日期：2000-01-01 00:00:00

abstract：:Lung cancer is the number one cause of death from cancer in the United States. Currently, there is no official recommendation to screen for lung cancer even in high-risk populations. Accordingly, we wait for patients to present with symptoms. Only 15-20% of patients are stage I lung cancer at diagnosis. Past screening...

journal_title：Seminars in respiratory and critical care medicine

authors： Jett JR

更新日期：2000-01-01 00:00:00

abstract：:Increasing donor availability for organ transplantation requires attention to factors that are potentially modifiable. The potential pool of available organs can theoretically be enlarged by considering new sources of organs, including non-beating heart donors, live donor lobar transplants, xenotransplants, and in vit...

journal_title：Seminars in respiratory and critical care medicine

authors： Williams TJ,Snell GI

更新日期：2001-10-01 00:00:00

abstract：:Sarcoidosis is a granulomatous disease of unknown etiology that involves the lungs or intrathoracic lymph nodes in more than 90% of patients. The clinical spectrum of sarcoidosis is protean, but pulmonary manifestations often dominate. Chest radiographs are abnormal in 90 to 95% of patients with sarcoidosis; the most ...

journal_title：Seminars in respiratory and critical care medicine

authors： Lynch JP 3rd

更新日期：2003-08-01 00:00:00

abstract：:This review summarizes the effects of beta2-agonists on asthma severity. There has been a controversy as to whether the regularly scheduled use of beta2-adrenergic agonists increases the risk of adverse outcomes in asthma. A number of epidemiological and clinical studies have found an association between the regularly...

journal_title：Seminars in respiratory and critical care medicine

authors： Ford JG,Iqbal J,Sunmonu Y

更新日期：2002-08-01 00:00:00

abstract：:The genus Scedosporium comprises a group of filamentous fungi found ubiquitously in the environment. The two major human pathogens within this genus are S. apiospermum-the asexual state of Pseudallescheria boydii-and S. prolificans. Both histologically resemble Aspergillus species, with hyphae that are septated and br...

journal_title：Seminars in respiratory and critical care medicine

authors： Panackal AA,Marr KA

更新日期：2004-04-01 00:00:00

abstract：:Practicing pulmonologists are often faced with the question of whether a lung disease is related to something in the patient's workplace, home, or recreational environment. Recognizing a lung disease as exposure related creates both opportunities and obligations for clinicians. In addition to managing the patient, the...

journal_title：Seminars in respiratory and critical care medicine

authors： Rose CS,Lynch DA,Cool CD

更新日期：2008-12-01 00:00:00

abstract：:In endemic areas, dimorphic fungal infections due to Histoplasma capsulatum, Blastomyces dermatitidis, and Coccidioides posadasii/immitis account for up to 30% of cases of community-acquired pneumonia. Because respiratory manifestations are often indistinguishable from common bacterial causes of pneumonia, the diagnos...

journal_title：Seminars in respiratory and critical care medicine

authors： Azar MM,Malo J,Hage CA

更新日期：2020-08-01 00:00:00

abstract：:The nontuberculous mycobacteria (NTM) are typically environmental organisms residing in soil and water. Although generally of low pathogenicity to humans, NTM can cause a wide array of clinical diseases; pulmonary disease is most frequent, followed by lymphadenitis in children, skin disease by M. marinum (particularly...

journal_title：Seminars in respiratory and critical care medicine

authors： van Ingen J

更新日期：2013-02-01 00:00:00

abstract：:Patients with severe infections are often treated with multiple courses of antibiotics in the intensive care unit (ICU), making the ICU a true antibiotic hotspot. The increasing incidence of multidrug resistance worldwide emphasizes the need for continued efforts in developing and implementing antibiotic stewardship p...

journal_title：Seminars in respiratory and critical care medicine

authors： Fierens J,Depuydt PO,De Waele JJ

更新日期：2019-08-01 00:00:00

abstract：:Pulmonary arterial hypertension (PAH) in the pediatric population is associated with a variety of underlying diseases and causes, significantly morbidity and mortality. In the majority of patients, PAH in children is idiopathic or associated with congenital heart disease (CHD), with pulmonary hypertension (PH) associa...

journal_title：Seminars in respiratory and critical care medicine

authors： Takatsuki S,Ivy DD

更新日期：2013-10-01 00:00:00

abstract：:Cardiopulmonary resuscitation (CPR) is performed frequently by paramedics, emergency department personnel, and inpatient physicians. Unfortunately, after more than 40 years of practice and study, there are still many controversies and unresolved treatment issues. This article focuses on four current controversies in C...

journal_title：Seminars in respiratory and critical care medicine

authors： White SJ,Himes D,Rouhani M,Slovis CM

更新日期：2001-01-01 00:00:00

abstract：:The evolution of scientific investigation in acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) is replete with examples of effective bench-to-bedside transitions, pioneering research methodology, and international collaboration. This article highlights for clinicians a selection of challenges and ...

journal_title：Seminars in respiratory and critical care medicine

authors： Meade MO,Lamontagne F

更新日期：2013-08-01 00:00:00

abstract：:Pandemics of influenza have been reported since the early sixteenth century. Recent pandemics include the Spanish flu (H1N1) from 1918 to 1920 (resulting in approximately 50 million deaths worldwide); the Asian flu (H2N2) from 1957 to 1958 (resulting in more than 1 million deaths); the Hong Kong flu (H3N2) from 1968 t...

journal_title：Seminars in respiratory and critical care medicine

authors： Rajagopal S,Treanor J

更新日期：2007-04-01 00:00:00

abstract：:The overarching goals of early sepsis management include early recognition, appropriate antibiotic therapy and source control, maintenance of hemodynamic stability, and supportive care of organ dysfunction. Despite increasing awareness of the global burden of sepsis, and general agreement on the goals of management, t...

journal_title：Seminars in respiratory and critical care medicine

authors： Moss SR,Prescott HC

更新日期：2019-10-01 00:00:00

abstract：:In patients with acute intracerebral hemorrhage (ICH), one of the major concerns is ongoing bleeding or ICH expansion. Anticoagulated patients are at higher risk of ongoing expansion and worse outcome. It may be that rapid anticoagulation reversal can reduce the risk of expansion and improve clinical outcome. For thos...

journal_title：Seminars in respiratory and critical care medicine

authors： Fuh L,Sin JH,Goldstein JN,Hayes BD

更新日期：2017-12-01 00:00:00

abstract：:Acute exacerbations of chronic bronchitis (AECBs) are one of the major causes of morbidity and mortality in the United States, resulting in significant cost to the health care system. Epidemiological information on chronic bronchitis is abundant and has been collected in most industrialized countries. The epidemiology...

journal_title：Seminars in respiratory and critical care medicine

authors： Kim N,Leeper KV Jr

更新日期：2000-01-01 00:00:00

abstract：:Hematologic factors, in particular platelets and the coagulation system, play an important role in the pathogenesis of organ failure in the intensive care unit. Failure of these hematologic systems is common in intensive care patients and may range from isolated thrombocytopenia or prolonged global clotting tests to c...

journal_title：Seminars in respiratory and critical care medicine

authors： Levi M,Schultz M

更新日期：2011-10-01 00:00:00

abstract：:Non-small cell lung cancer (NSCLC) is primarily a disease of the elderly. Although NSCLC is the leading cause of cancer death in the United States and the overall prognosis of this disease is poor, treatment improves survival compared with best supportive care, independent of the stage of disease. Elderly patients hav...

journal_title：Seminars in respiratory and critical care medicine

authors： Sequist LV,Fidias P

更新日期：2005-06-01 00:00:00

abstract：:Daily oral care with chlorhexidine for mechanically ventilated patients is ubiquitous in contemporary intensive care practice. The practice is predicated upon meta-analyses suggesting that adding chlorhexidine to daily oral care regimens can reduce ventilator-associated pneumonia (VAP) rates by up to 40%. Close analys...

journal_title：Seminars in respiratory and critical care medicine

authors： Klompas M

更新日期：2017-06-01 00:00:00