Coagulation Pathways, Hemostasis, and Thrombosis in Liver Failure.

abstract：:The sleep of intensive care unit (ICU) patients is remarkably disrupted. Several studies, employing both subjective and objective measures of sleep quality, have demonstrated that critically ill patients exhibit severe sleep fragmentation and reduced restorative sleep, particularly a suppression of rapid eye movement ...

journal_title：Seminars in respiratory and critical care medicine

authors： Cooper AB,Gabor JY,Hanly PJ

更新日期：2001-01-01 00:00:00

abstract：:Idiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disease of unknown cause, occurring in adults, limited to the lungs and associated with the pathologic and radiologic pattern of usual interstitial pneumonia. Prognosis is poor, and most patients die of respiratory failure within 3 to 6 years from the o...

journal_title：Seminars in respiratory and critical care medicine

authors： Puglisi S,Torrisi SE,Giuliano R,Vindigni V,Vancheri C

更新日期：2016-06-01 00:00:00

abstract：:Coccidioidomycosis manifests as a variety of clinical manifestations and ranges in severity from asymptomatic exposure with resultant immunity to reinfection, to fulminant, and life-threatening disseminated disease. Primary coccidioidal pneumonia represents the most common clinical form of infection, and the incidence...

journal_title：Seminars in respiratory and critical care medicine

authors： Twarog M,Thompson GR 3rd

更新日期：2015-10-01 00:00:00

abstract：:Critical illness evoked by trauma, extensive surgery, or severe medical illnesses is the ultimate example of acute severe physical stress. The endocrine response in a critically injured and stressed patient is varied and complex. Although the acute and chronic phases of critical illness are characterized by distinct e...

journal_title：Seminars in respiratory and critical care medicine

authors： Raghavan M,Marik PE

更新日期：2006-06-01 00:00:00

abstract：:Hepatic sarcoidosis is a relatively common manifestation of extrapulmonary sarcoidosis. It occurs in 20 to 30% of cases and is rarely severe. However, a cluster of patients may develop severe complications such as cirrhosis and portal hypertension. In this review, we describe the current knowledge of clinical, biologi...

journal_title：Seminars in respiratory and critical care medicine

authors： Rossi G,Ziol M,Roulot D,Valeyre D,Mahévas M

更新日期：2020-10-01 00:00:00

abstract：:Assisted mechanical ventilation (MV) may be a favorable alternative to controlled MV at the early phase of acute respiratory distress syndrome (ARDS), since it requires less sedation, no paralysis and is associated with less hemodynamic deterioration, better distal organ perfusion, and lung protection, thus reducing t...

journal_title：Seminars in respiratory and critical care medicine

authors： Saddy F,Sutherasan Y,Rocco PR,Pelosi P

更新日期：2014-08-01 00:00:00

abstract：:Pulmonary arterial hypertension (PAH) is defined as a mean pulmonary artery pressure greater then 25 mm Hg at rest and greater then 30 mm Hg with exercise in association with normal left heart filling pressures. However, many patients with PAH have much higher pulmonary artery pressures, which, untreated, can rapidly ...

journal_title：Seminars in respiratory and critical care medicine

authors： Bull TM

更新日期：2005-08-01 00:00:00

abstract：:Lung transplantation is a therapeutic option for patients with end stage lung diseases, but long-term survival remains poor, primarily due to chronic allograft rejection. Bronchiolitis obliterans (BO), a fibrotic process resulting in progressive narrowing of bronchiolar lumens and airflow obstruction, is a manifestati...

journal_title：Seminars in respiratory and critical care medicine

authors： Belperio JA,Lake K,Tazelaar H,Keane MP,Strieter RM,Lynch JP 3rd

更新日期：2003-10-01 00:00:00

abstract：:Increasing donor availability for organ transplantation requires attention to factors that are potentially modifiable. The potential pool of available organs can theoretically be enlarged by considering new sources of organs, including non-beating heart donors, live donor lobar transplants, xenotransplants, and in vit...

journal_title：Seminars in respiratory and critical care medicine

authors： Williams TJ,Snell GI

更新日期：2001-10-01 00:00:00

abstract：:Despite significant progress in the field of transplant immunology, acute cellular rejection (ACR) remains a very frequent complication after lung transplantation (LTx), with almost 30% of LTx recipients experiencing at least one episode of treated ACR during the first year of follow-up. Most episodes respond to the f...

journal_title：Seminars in respiratory and critical care medicine

authors： Koutsokera A,Levy L,Pal P,Orchanian-Cheff A,Martinu T

更新日期：2018-04-01 00:00:00

abstract：:Mycoplasma pneumoniae infection occurs worldwide and is the most common cause of community-acquired pneumonia (CAP) in 5- to 20-year-olds. The most reliable diagnostic test is the enzyme immunoassay, which allows immunoglobulin (Ig)G and IgM titration and presents 92% sensitivity and 95% specificity on paired samples....

journal_title：Seminars in respiratory and critical care medicine

authors： Blasi F,Tarsia P,Aliberti S,Cosentini R,Allegra L

更新日期：2005-12-01 00:00:00

abstract：:Invasive fungal infections, especially candidemia and systemic candidiasis, have become a major cause of morbidity and mortality in the last few decades. This comes in parallel with the major advances made in intensive care. Patients who are critically ill, in medical or surgical ICUs are especially at risk for CANDID...

journal_title：Seminars in respiratory and critical care medicine

authors： Vazquez JA

更新日期：2010-02-01 00:00:00

abstract：:The use of predictive models has been proposed as a potential tool to reduce maternal morbidity and mortality, by aiding in the timely identification of potential high-risk patients. Prognostic models in critical care have been used to characterize the severity of illness of specific diseases. Physiological changes in...

journal_title：Seminars in respiratory and critical care medicine

authors： Levinson A,Miranda J,Rojas-Suarez JA

更新日期：2017-04-01 00:00:00

abstract：:This review summarizes the effects of beta2-agonists on asthma severity. There has been a controversy as to whether the regularly scheduled use of beta2-adrenergic agonists increases the risk of adverse outcomes in asthma. A number of epidemiological and clinical studies have found an association between the regularly...

journal_title：Seminars in respiratory and critical care medicine

authors： Ford JG,Iqbal J,Sunmonu Y

更新日期：2002-08-01 00:00:00

abstract：:Hematologic factors, in particular platelets and the coagulation system, play an important role in the pathogenesis of organ failure in the intensive care unit. Failure of these hematologic systems is common in intensive care patients and may range from isolated thrombocytopenia or prolonged global clotting tests to c...

journal_title：Seminars in respiratory and critical care medicine

authors： Levi M,Schultz M

更新日期：2011-10-01 00:00:00

abstract：:Invasive candidiasis (IC) is the most frequent health care associated invasive fungal infection. It is also associated with high morbidity, mortality, and cost. The most frequent etiologic agent is Candida albicans, but non-albicans species are increasing and associated with reduced antifungal susceptibility and outbr...

journal_title：Seminars in respiratory and critical care medicine

authors： Gonzalez-Lara MF,Ostrosky-Zeichner L

更新日期：2020-02-01 00:00:00

abstract：:Chronic pulmonary sepsis is the predominant cause of morbidity for patients with cystic fibrosis (CF) and non-CF bronchiectasis. Previously it was thought that respiratory infection in these patients was mostly limited to a very small number of typical pathogens; however, in recent years there have been increasing rep...

journal_title：Seminars in respiratory and critical care medicine

authors： Green H,Jones AM

更新日期：2015-04-01 00:00:00

abstract：:In heart failure (HF), pleural effusion results from increased interstitial fluid in the lung due to elevated pulmonary capillary pressure. Rarely, pleural effusions may occur in association with isolated right HF. HF-associated effusions are typically bilateral, but if unilateral, they are more commonly seen on the r...

journal_title：Seminars in respiratory and critical care medicine

authors： Porcel JM

更新日期：2010-12-01 00:00:00

abstract：:The vasculitides affecting large and medium-sized vessels are heterogeneous. This group includes such disorders as giant cell arteritis, Takayasu's disease, and sarcoidosis. There are several challenges that may arise in the care of patients with these disorders. Diagnosis may be elusive when initially evaluating pati...

journal_title：Seminars in respiratory and critical care medicine

authors： Maksimowicz-McKinnon K,Hoffman GS

更新日期：2004-10-01 00:00:00

abstract：:This article reviews recent developments in the selection, assessment, and management of the potential lung donor, which aim to increase donor organ use. The scarcity of suitable donor organs continues to limit lung transplantation, but the situation is changing. An expanded donor pool, including the now widespread us...

journal_title：Seminars in respiratory and critical care medicine

authors： Snell GI,Paraskeva M,Westall GP

更新日期：2013-06-01 00:00:00

abstract：:Paracoccidioidomycosis (formerly known as South American blastomycosis) is produced by the thermally dimorphic fungus Paracoccidioides brasiliensis. Most often this mycosis runs a chronic progressive course affecting preferentially the lungs followed by the skin, mucous membranes, adrenals, and reticuloendothelial org...

journal_title：Seminars in respiratory and critical care medicine

authors： Restrepo A,Benard G,de Castro CC,Agudelo CA,Tobón AM

更新日期：2008-04-01 00:00:00

abstract：:The nontuberculous mycobacteria (NTM) are typically environmental organisms residing in soil and water. Although generally of low pathogenicity to humans, NTM can cause a wide array of clinical diseases; pulmonary disease is most frequent, followed by lymphadenitis in children, skin disease by M. marinum (particularly...

journal_title：Seminars in respiratory and critical care medicine

authors： van Ingen J

更新日期：2013-02-01 00:00:00

abstract：:Practicing pulmonologists are often faced with the question of whether a lung disease is related to something in the patient's workplace, home, or recreational environment. Recognizing a lung disease as exposure related creates both opportunities and obligations for clinicians. In addition to managing the patient, the...

journal_title：Seminars in respiratory and critical care medicine

authors： Rose CS,Lynch DA,Cool CD

更新日期：2008-12-01 00:00:00

abstract：:Current research indicates that the majority of survivors of critical illness develop post-intensive care syndrome (PICS), which includes new or worsening cognitive or psychiatric disorders that persist for months to years after critical illness. These cognitive impairments and psychiatric disorders are profound and l...

journal_title：Seminars in respiratory and critical care medicine

authors： Hopkins RO,Girard TD

更新日期：2012-08-01 00:00:00

abstract：:Hyperoxia, or excess oxygen supplementation, prevails in the intensive care unit (ICU) without a beneficial effect and, in some instances, may cause harm. Recent interest and surge in clinical studies in mechanically ventilated critically ill patients has brought this to the attention of clinicians and researchers. Hy...

journal_title：Seminars in respiratory and critical care medicine

authors： Pannu SR

更新日期：2016-02-01 00:00:00

abstract：:Massive pulmonary embolism (PE) refers to large emboli that cause hemodynamic instability, right ventricular failure, and circulatory collapse. According to the 2016 ACCP Antithrombotic Guidelines, therapy for massive PE should include systemic thrombolytic therapy in conjunction with anticoagulation and supportive ca...

journal_title：Seminars in respiratory and critical care medicine

authors： Weinberg A,Tapson VF,Ramzy D

更新日期：2017-02-01 00:00:00

abstract：:The increasing prevalence and recognition of obstructive sleep apnea (OSA) coupled with an awareness of its detrimental health consequences has resulted in the need for timely and cost efficient access to diagnostic sleep testing and treatment. As a result, increased emphasis is being placed on simplified ambulatory m...

journal_title：Seminars in respiratory and critical care medicine

authors： Cruz SD,Littner MR,Zeidler MR

更新日期：2014-10-01 00:00:00

abstract：:The genus Scedosporium comprises a group of filamentous fungi found ubiquitously in the environment. The two major human pathogens within this genus are S. apiospermum-the asexual state of Pseudallescheria boydii-and S. prolificans. Both histologically resemble Aspergillus species, with hyphae that are septated and br...

journal_title：Seminars in respiratory and critical care medicine

authors： Panackal AA,Marr KA

更新日期：2004-04-01 00:00:00

abstract：:Intensive care unit (ICU) acquired pneumonia is one of the most common and morbid health care-associated infections. Despite decades of work developing and testing prevention strategies, ICU-acquired pneumonia remains stubbornly pervasive. Pneumonia prevention studies are difficult to interpret because all are at risk...

journal_title：Seminars in respiratory and critical care medicine

authors： Klompas M

更新日期：2019-08-01 00:00:00

abstract：:Mycobacterial infections have caused enormous morbidity and mortality in people living with human immunodeficiency virus (HIV) infection. Of these, the most devastating has been tuberculosis (TB), the leading cause of death among HIV-positive persons globally. TB has killed more people living with HIV than any other i...

journal_title：Seminars in respiratory and critical care medicine

authors： Haas MK,Daley CL

更新日期：2016-04-01 00:00:00