Effects of Migration on Allergic Diseases.

Abstract:

:Studies in migrant populations provide vital opportunities to investigate the role of environmental factors in the pathogenesis of allergic disorders. Differences in allergy prevalence have been observed between migrants and native-born subjects living in the same geographical location. Immigrants who migrate from less affluent countries with lower allergy prevalence tend to have a lower prevalence of allergic disorders compared to native-born residents of the more affluent host country. The patterns of allergic disease prevalence also differ between first- and second-generation migrants. The timing of migration in relation to birth, age at migration, and duration of residence in the host country also influence one's atopic risk. A complex interplay of multiple environmental, socioeconomic, and cultural factors is likely responsible for these observed differences. Further research into the roles of various risk factors in modulating differences in allergic disease prevalence between migrant and native populations will enhance our understanding of the complex gene-environment interactions involved in the pathogenesis of allergic disorders.

authors

Tham EH,Loo EXL,Zhu Y,Shek LP

doi

10.1159/000494129

subject

Has Abstract

pub_date

2019-01-01 00:00:00

pages

128-140

issue

2

eissn

1018-2438

issn

1423-0097

pii

000494129

journal_volume

178

pub_type

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