Abstract:
:Complicated stages of diabetes are the major cause of Diabetic Retinopathy (DR) and no symptoms appear at the initial stage of DR. At the early stage diagnosis of DR, screening and treatment may reduce vision harm. In this work, an automated technique is applied for detection and classification of DR. A local contrast enhancement method is used on grayscale images to enhance the region of interest. An adaptive threshold method with mathematical morphology is used for the accurate lesions region segmentation. After that, the geometrical and statistical features are fused for better classification. The proposed method is validated on DIARETDB1, E-ophtha, Messidor, and local data sets with different metrics such as area under the curve (AUC) and accuracy (ACC).
journal_name
Microsc Res Techjournal_title
Microscopy research and techniqueauthors
Amin J,Sharif M,Rehman A,Raza M,Mufti MRdoi
10.1002/jemt.23063subject
Has Abstractpub_date
2018-09-01 00:00:00pages
990-996issue
9eissn
1059-910Xissn
1097-0029journal_volume
81pub_type
杂志文章abstract::Natriuretic peptides (NP), together with nitric oxide (NO) are powerful relaxing factors acting via a common second messenger, cyclic GMP (cGMP). Together with other vasoactive modulators, these vasorelaxing factors play an essential role in regulating the function of kidney glomeruli. The presence of NP receptors in ...
journal_title:Microscopy research and technique
pub_type: 杂志文章,评审
doi:10.1002/jemt.10080
更新日期:2002-05-15 00:00:00
abstract::Using high resolution transmission electron microscopy with image simulation and Fourier analysis, the Li1- x FePO4 (x < 0.01), Li1- x FePO4 (x ∼ 0.5), and FePO4 particles, prepared by charging or discharging the 053048 electrochemical cells (thickness: 5 mm, width: 30 mm, height: 48 mm) and dismantled inside an Ar-fi...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.22495
更新日期:2015-06-01 00:00:00
abstract::This study investigated the relationship between enteroendocrine and mucus-secreting cells distribution, the severity of colonic mucosal injury and intestinal motility in experimental colorectal carcinogenesis. Using a standardized murine model of colorectal carcinogenesis, eight-weeks-old female Wistar rats weighting...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.22534
更新日期:2016-01-01 00:00:00
abstract::The surface epithelial cells of the ovary, which are modified peritoneal cells, form a single, focally pseudostratified layer. The Müllerian ducts differentiate after invagination of the coelomic mesothelium over the gonadal ridges during the 6th week of embryonic life. On the basis of the embryologically putative Mül...
journal_title:Microscopy research and technique
pub_type: 杂志文章,评审
doi:10.1002/jemt.20306
更新日期:2006-06-01 00:00:00
abstract::We present a semiautomated software solution to the problem of extending the lateral field of view of a classical microscope. The initial requirements are a set of overlapping images, along with their user-provided coarse mosaic. Our solution then refines this initial mosaic in a fully automatic fashion. We rely on a ...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.20393
更新日期:2007-02-01 00:00:00
abstract::We have summarized current knowledge on the aging of the immune system in three vertebrate groups: fish, amphibians and birds. Available data are few due to difficulties in studying ageing in natural populations and in accurately determining age. In all vertebrates, the most obvious evidence of the senescence of lymph...
journal_title:Microscopy research and technique
pub_type: 杂志文章,评审
doi:10.1002/jemt.10409
更新日期:2003-12-15 00:00:00
abstract::It is increasingly recognized that neuroepithelial endocrine cells and organoid clusters of these cells termed neuroepithelial bodies are widely distributed in the respiratory tract of vertebrates. This review focuses on the neuroepithelial endocrine system in the airway epithelium of mammals according to observations...
journal_title:Microscopy research and technique
pub_type: 杂志文章,评审
doi:10.1002/(SICI)1097-0029(19970401)37:1<31::AID-JEMT
更新日期:1997-04-01 00:00:00
abstract::Golgi impregnations reveal a variety of dendritic morphologies amongst Kenyon cells in the mushroom bodies of Drosophila melanogaster. Different morphological types of Kenyon cells contribute axon-like processes to five divisions of the medial and vertical lobes. Four of these divisions have characteristic affinities ...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.10368
更新日期:2003-10-01 00:00:00
abstract::Ensheathing cells are the glial cells that envelop olfactory axons as they course from the olfactory epithelium to the bulb. They are derived from the olfactory placode and differ from the typical glia in terms of sharing the phenotypes of both astrocytes and Schwann cells. The aims of this study are to review (1) cel...
journal_title:Microscopy research and technique
pub_type: 杂志文章,评审
doi:10.1002/jemt.10151
更新日期:2002-08-01 00:00:00
abstract::Various types of mirror lenses were developed some decades ago designed for several special tasks in microscopy. When compared with high-end glass lenses, mirror lenses lead to an extraordinary image quality because of their supraapochromatic color fidelity and their high planarity; the working distances are significa...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.20809
更新日期:2010-07-01 00:00:00
abstract::The present study focused to elucidate the promising role of probiotics in the fish culture, by employing microscopic and biochemical parameters to rationalize the possible outcomes. After preliminary feeding trial histopathological analysis revealed clear and visible changes in the intestinal and liver cells of CTRL ...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.23416
更新日期:2020-03-01 00:00:00
abstract::Zinc is one of the most abundant oligoelements in the living cell. It appears tightly bound to metallothioneins, loosely bound to some metalloproteins and nucleic acids, or even as free ion. Small amounts of zinc ions (in the nanomolar range) regulate a plentitude of enzymatic proteins, receptors, and transcription fa...
journal_title:Microscopy research and technique
pub_type: 杂志文章,评审
doi:10.1002/jemt.10037
更新日期:2002-03-01 00:00:00
abstract::The enzyme adenylyl cyclase (AC) plays a pivotal role in smooth muscle relaxation. Biochemical evidence suggests that AC is predominantly located in the outer layers of the myometrium; however, neither immunocytochemical nor histochemical studies have been undertaken to demonstrate the specific cellular distribution o...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0029(19980301)40:6<488::AID-JEM
更新日期:1998-03-15 00:00:00
abstract::Changes in the intracellular Ca2+ concentration ([Ca2+]i) within CA1 hippocampal pyramidal neurons were imaged using confocal laser scanning microscopy in conjunction with Ca(2+)-sensitive fluorescent indicators. The imaging was performed in thick hippocampal brain slices while simultaneously measuring or controlling ...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.1070290404
更新日期:1994-11-01 00:00:00
abstract::In the search for a new methodological approach applicable to the determination of the still poorly known primary role of boron in plant physiology, we have undertaken to appraise the potential of the SIMS method for the analytical imaging of the boron isotopes, (10)B and (11)B, at physiological concentrations in plan...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.10125
更新日期:2002-07-15 00:00:00
abstract::The peripheral arterial chemoreceptors of the carotid body participate in the ventilatory responses to hypoxia and hypercapnia, the arousal responses to asphyxial apnea, and the acclimatization to high altitude. In response to an excitatory stimuli, glomus cells in the carotid body depolarize, their intracellular calc...
journal_title:Microscopy research and technique
pub_type: 杂志文章,评审
doi:10.1002/jemt.10190
更新日期:2002-11-01 00:00:00
abstract::In order to understand the interaction between dendritic cells (DCs) and helper T (Th) cells in the region exposed to antigens during pulmonary delayed-type hypersensitivity (DTH), which is considered to be mediated by Th1 cells, we immunohistochemically investigated their spatial relationship in the cellular infiltra...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.1091
更新日期:2001-05-15 00:00:00
abstract::Transgenic mice are valuable experimental models of human endocrine diseases. Targeted ablation of specific cell lineages or insertion of genes coding for releasing factors, hormones, growth factors, and oncogenes fused with appropriate promoters, or mutated genes, can induce several pituitary disorders. Various hypos...
journal_title:Microscopy research and technique
pub_type: 杂志文章,评审
doi:10.1002/(SICI)1097-0029(19971015)39:2<194::AID-JEM
更新日期:1997-10-15 00:00:00
abstract::An analytical result is given for the wavelength at which two or more first order Laue zone (FOLZ) lines intersect at a single point on the positive x axis when a face centred cubic crystal is observed in the convergent beam mode with the beam axis parallel to the [100] direction. The position of the intersection alon...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.1070290311
更新日期:1994-10-15 00:00:00
abstract::A new and improved technique for microvascular corrosion casting was developed and verified by examination of corrosion casts of 90 bovine limbs. The described technique renders a complete filling of the vasculature of the claw even in regions that hitherto proved to be difficult regarding completeness of filling such...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0029(19990501)45:3<184::AID-JEM
更新日期:1999-05-01 00:00:00
abstract::Nowadays the processes of crossing of different mammalian species are well characterized in light of genetics, and possibility of reproduction. Generally, lack detailed studies on changes in anatomy and histology of internal systems of hybrids. Bison bonasus hybrid is an interspecific species between the bull of Europ...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.23516
更新日期:2020-10-01 00:00:00
abstract::Superior cervical ganglion neurons (SCGNs) were isolated from 7-day-old rat SCG and cultured in MEM containing horse serum, fetal calf serum, and nerve growth factor. In this culture condition, it is well known that the SCGNs form cholinergic synapse. In 3-4 weeks cultured neurons, immunofluorescent staining for synap...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.1070290206
更新日期:1994-10-01 00:00:00
abstract::Infection of humans with Helicobacter pylori results in the development of chronic gastritis and plays an important role in gastric ulcer pathogenesis. Despite the infiltration of the mucosa with specific immunocompetent cells and production of specific antibodies, the infection usually persists for life. This study w...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.1111
更新日期:2001-06-15 00:00:00
abstract::The purpose of this study is to determine the possible changes in the localization of the four Epidermal Growth Factor Receptors and three ligands in quail lungs from the first day of hatching until the 125th after hatching using immunohistochemical methods. Immunohistochemical results demonstrated that four EGFRs and...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.22544
更新日期:2015-09-01 00:00:00
abstract::Macro and microdissection methods, conventional histology and immunohistochemical procedures were used to investigate the nasal cavity and turbinate complex in fetal and adult sheep, with special attention to the ethmoturbinates, the vestibular mucosa, and the septal mucosa posterior to the vomeronasal organ. The ecto...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.22436
更新日期:2014-12-01 00:00:00
abstract::This bibliography is compiled to assist in locating papers related to the application of scanning electron microscopy (SEM) to cerebrospinal-fluid-contacting surfaces in vertebrates. The use of SEM by neuroscientists has continued apace since the publication of the first bibliography in 1980. SEM studies now include m...
journal_title:Microscopy research and technique
pub_type:
doi:10.1002/(SICI)1097-0029(19980415)41:2<158::AID-JEM
更新日期:1998-04-15 00:00:00
abstract::On continuing our studies on head and neck neoplasia, specimens from salivary gland tumors have been explored by using infrared microimaging spectroscopy to discern healthy from neoplastic tissues. Samples with Warthin tumor, epithelial displasia, marginal B-cell lymphoma, low-grade adenocarcinoma, and adenoid cystic ...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.20644
更新日期:2009-02-01 00:00:00
abstract::A homemade colloidal probe atomic force microscope was used to perform nanoindentation with a spherical probe of 5 microm in diameter, at different approach velocities in order to extract the Young's modulus, E0, of poly(L-lysine)/hyaluronan (PLL/HA) films. This parameter is of prime importance to control cellular adh...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.20275
更新日期:2006-02-01 00:00:00
abstract::Human monocytic leukemia U937 cells readily undergo apoptosis when exposed to various stimuli, including inhibition of protein synthesis, oxidative stress, antitumoral agents, etc. The sequential, step-by-step morphological changes in U937 cells that occur during the apoptotic program are largely determined by the act...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.20058
更新日期:2004-05-01 00:00:00
abstract::Directed growth cone movement is crucial for the correct wiring of the nervous system. This movement is governed by the concerted actions of cell surface receptors, signaling proteins, cytoskeleton-associated molecules, and molecular motors. In order to investigate the molecular basis of growth cone motility, we appli...
journal_title:Microscopy research and technique
pub_type: 杂志文章,评审
doi:10.1002/(SICI)1097-0029(20000115)48:2<97::AID-JEMT
更新日期:2000-01-15 00:00:00