Abstract:
:Pasting properties are important characteristics of barley starch from a processing standpoint. Many studies reported the close relationship between pasting properties and malting quality, especially malt extract. However, most conclusions were derived from the correlation between pasting properties and malting quality using a set of cultivars or breeding lines. In this study, a doubled haploid population of 150 lines from a cross between a Japanese malting barley and a Chinese feed barley was grown in four different environments (two sites × two years). Based on average values from all different environments, 17 significant quantitative trait loci (QTL) were identified for pasting properties. The genetic variance explained by these QTL varied from 7.0 to 23.2%. Most QTL controlling pasting properties were located on 1H, 2H, 5H, and 7H. Results confirmed the linkage between pasting properties and malt extract, with most of the QTL for pasting properties becoming nonsignificant when using malt extract as a covariate. Breakdown showed the closest correlation with malt extract. Molecular markers closely linked to the QTL can be used to select desired pasting properties to improve malting quality.
journal_name
Int J Mol Scijournal_title
International journal of molecular sciencesauthors
Wang J,Yang J,Hua W,Wu X,Zhu J,Shang Y,Zhou Mdoi
10.3390/ijms19113559subject
Has Abstractpub_date
2018-11-12 00:00:00issue
11issn
1422-0067pii
ijms19113559journal_volume
19pub_type
杂志文章abstract::DNA G-quadruplexes (G4s) form in relevant genomic regions and intervene in several biological processes, including the modulation of oncogenes expression, and are potential anticancer drug targets. The human KRAS proto-oncogene promoter region contains guanine-rich sequences able to fold into G4 structures. Here, by u...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms22010448
更新日期:2021-01-05 00:00:00
abstract::Epithelial ovarian cancer (EOC) is the deadliest tumor among gynecological cancer in the industrialized countries. The EOC incidence and mortality have remained unchanged over the last 30 years, despite the progress in diagnosis and treatment. In order to develop novel and more effective therapeutic approaches, the mo...
journal_title:International journal of molecular sciences
pub_type: 杂志文章,评审
doi:10.3390/ijms17091387
更新日期:2016-08-23 00:00:00
abstract::The DNA repair gene X-ray cross-complementary group 4 (XRCC4), an important caretaker of the overall genome stability, is thought to play a major role in human tumorigenesis. We investigated the association between an important polymorphic variant of this gene at codon 247 (rs373409) and diffusely infiltrating astrocy...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms15010250
更新日期:2013-12-27 00:00:00
abstract::Virus-like nanoparticles (VLNPs) have been studied extensively as nanocarriers for targeted drug delivery to cancer cells. However, VLNPs have intrinsic drawbacks, in particular, potential antigenicity and immunogenicity, which hamper their clinical applications. Thus, they can be eliminated easily and rapidly by host...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms20194903
更新日期:2019-10-03 00:00:00
abstract::Head and neck squamous cell carcinoma (HNSCC) is often diagnosed at an advanced stage and has a dismal prognosis. Nearly 10 years after the approval of cetuximab, anti-PD1/PD-L1 checkpoint inhibitors are the first drugs that have shown any survival benefit for the treatment on platinum-refractory recurrent/metastatic ...
journal_title:International journal of molecular sciences
pub_type: 杂志文章,评审
doi:10.3390/ijms20215399
更新日期:2019-10-30 00:00:00
abstract::Ovarian cancer is one of the commonest gynecologic malignancies, which has a poor prognosis for patients at the advanced stage. Isoliquiritigenin (ISL), an active flavonoid component of the licorice plant, previously demonstrated antioxidant, anti-inflammatory, and tumor suppressive effects. In this study, we investig...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms18102025
更新日期:2017-09-21 00:00:00
abstract::Rice (Oryza sativa L.) is a widely cultivated food crop around the world, especially in Asia. However, rice seedlings often suffer from cold stress, which affects their growth and yield. Here, RNA-seq analysis and Meta-QTLs mapping were performed to understand the molecular mechanisms underlying cold tolerance in the ...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms21134615
更新日期:2020-06-29 00:00:00
abstract::The aim of this study was to develop and evaluate matrix assisted LASER desorption ionization (MALDI) time-of-flight (TOF) mass spectrometry imaging (MSI) of blood smear. Integrated light microscope and MALDI IT-TOF mass spectrometer, together with a matrix sublimation device, were used for analysis of blood smears co...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms22020585
更新日期:2021-01-08 00:00:00
abstract::The adaptation of adenoviruses as gene delivery tools has resulted in the development of high-capacity adenoviral vectors (HC-AdVs), also known, helper-dependent or "gutless". Compared with earlier generations (E1/E3-deleted vectors), HC-AdVs retain relevant features such as genetic stability, remarkable efficacy of i...
journal_title:International journal of molecular sciences
pub_type: 杂志文章,评审
doi:10.3390/ijms21103643
更新日期:2020-05-21 00:00:00
abstract::Ventricular arrhythmia (VA) is a major component of sudden cardiac death (SCD). To investigate the expression of brain natriuretic peptide (BNP), endothelin-1 (ET-1), and transforming growth factor-beta 1 (TGF-β1) during VA, we established a rat model of VA induced by BaCl2 solution through a microinjector pump. PD142...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms20235845
更新日期:2019-11-21 00:00:00
abstract::Mast cells (MC) are resident tissue cells found primarily at the interphase between tissues and the environment. These evolutionary old cells store large amounts of proteases within cytoplasmic granules, and one of the most abundant of these proteases is tryptase. To look deeper into the question of their in vivo targ...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms20205147
更新日期:2019-10-17 00:00:00
abstract::This paper explores the effect of granulocyte colony-stimulating factor (G-CSF) on mouse myocardial microvascular endothelial cell (CMECs) proliferation. CMECs were harvested from C57/BL6 mice. CMECs were cultured in medium containing G-CSF (0 ng/mL, 20 ng/mL, 40 ng/mL, 60 ng/mL) for five days. Proliferative activity ...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms12021306
更新日期:2011-02-22 00:00:00
abstract::To investigate the effect of pollination on the fruit quality of 'Dangshan Su' pear, 'Dangshan Su' was fertilized by the pollen of 'Wonhwang' (Pyrus pyrifolia Nakai.) (DW) and 'Jingbaili' (Pyrus ussuriensis Maxim.) (DJ). The analysis of primary metabolites was achieved through untargeted metabolomics, and the quantita...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms19082273
更新日期:2018-08-02 00:00:00
abstract::Acoustic wave biosensors are a real-time, label-free biosensor technology, which have been exploited for the detection of proteins and cells. One of the conventional biosensor approaches involves the immobilization of a monolayer of antibodies onto the surface of the acoustic wave device for the detection of a specifi...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms9020154
更新日期:2008-02-01 00:00:00
abstract::To examine the effect of melatonin given to rats simultaneously with fructose on initial and fully developed metabolic syndrome, male Wistar rats had free access to chow and 5% or 10% fructose drinking solution for 8 weeks. As compared to controls, systolic blood pressure augmented significantly under both treatments ...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms14022502
更新日期:2013-01-25 00:00:00
abstract::Peritoneal dialysis effluent (PDE) potentially carries an archive of peptides relevant to pathological processes in abdominal and surrounding tissues. Magnetic beads and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry is one such approach that offers a unique tool for profiling of peptides...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms15011162
更新日期:2014-01-16 00:00:00
abstract:BACKGROUND:Dp71 is the most abundant dystrophin (DMD) gene product in the nervous system. Mutation in the Dp71 coding region is associated with cognitive disturbances in Duchenne muscular dystrophy (DMD) patients, but the function of dystrophin Dp71 in tumor progression remains to be established. This study investigate...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms20215429
更新日期:2019-10-31 00:00:00
abstract::In this study, drug nanocarriers were designed using linear copolymers with different contents of cholinium-based ionic liquid units, i.e., [2-(methacryloyloxy)ethyl]trimethylammonium chloride (TMAMA/Cl: 25, 50, and 75 mol%). The amphiphilicity of the copolymers was evaluated on the basis of their critical micelle con...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms22010284
更新日期:2020-12-30 00:00:00
abstract::Asia-Pacific NMR (APNMR) has been an important scientific event in the region, engaging a large number of NMR scientists from academia and industries [...]. ...
journal_title:International journal of molecular sciences
pub_type: 社论
doi:10.3390/ijms21124419
更新日期:2020-06-22 00:00:00
abstract::The present study investigates the photochemical properties of potential photosensitizers for photodynamic therapy, namely four commercial heptamethinecyanine dyes (IR125, IR780, IR813, IR820). Spectroscopic studies were made by means of laser induced fluorescence and laser flash photolysis in order to obtain fluoresc...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms140918557
更新日期:2013-09-09 00:00:00
abstract::Fetal programming implies that the maternal diet during pregnancy affects the long-term health of offspring. Although maternal diet influences metabolic disorders and non-alcoholic fatty liver disease in offspring, the hepatic mechanisms related to metabolites are still unknown. Here, we investigated the maternal diet...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms21239060
更新日期:2020-11-28 00:00:00
abstract::The common carp can tolerate extremely low oxygen levels. These fish store zinc in a specific zinc-binding protein presented in digestive tract tissues, and under low oxygen, the stored zinc is released and used as a signal to stimulate erythropoiesis (red blood cell formation). To determine whether the environmental ...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms18010138
更新日期:2017-01-11 00:00:00
abstract::The strong association with the Major Histocompatibility Complex (MHC) class I genes represents a shared trait for a group of autoimmune/autoinflammatory disorders having in common immunopathogenetic basis as well as clinical features. Accordingly, the main risk factors for Ankylosing Spondylitis (AS), prototype of th...
journal_title:International journal of molecular sciences
pub_type: 杂志文章,评审
doi:10.3390/ijms21249608
更新日期:2020-12-17 00:00:00
abstract::Chondral or osteochondral defects are still controversial problems in orthopedics. Here, chondrocytes labeled with magnetic nanoparticles were cultivated on a biphasic, type II collagen-chitosan/poly(lactic-co-glycolic acid) scaffold in an attempt to develop cultures with trackable cells exhibiting growth, differentia...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms18010087
更新日期:2017-01-04 00:00:00
abstract::The majority of the human genome is comprised of non-protein-coding genes, but the relevance of non-coding RNAs in complex diseases has yet to be fully elucidated. One class of non-coding RNAs is long non-coding RNAs or lncRNAs, many of which have been identified to play a range of roles in transcription and translati...
journal_title:International journal of molecular sciences
pub_type: 杂志文章,评审
doi:10.3390/ijms22031094
更新日期:2021-01-22 00:00:00
abstract::Brain-derived neurotrophic factor (BDNF), a critical member of the neurotrophic family, plays an important role in multiple stress-related mental disorders. Although alterations in BDNF in multiple brain regions of individuals experiencing stress have been demonstrated in previous studies, it appears that a set of ele...
journal_title:International journal of molecular sciences
pub_type: 杂志文章,评审
doi:10.3390/ijms21041375
更新日期:2020-02-18 00:00:00
abstract::This study was conducted in order to determine the effect of priming with γ-aminobutyric acid (GABA) at 0.5 mM on rice (Oryza sativa L.) seed germination under osmotic stress (OS) induced by polyethylene glycol (30 g/L PEG 6000); and salinity stress (S, 150 mM NaCl) and their combination (OS+S). Priming with GABA sign...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms20225709
更新日期:2019-11-14 00:00:00
abstract::Since 2003, several loss-of-function mutations in the HCN4 gene, which encodes the HCN4 protein, have been associated with sinus node dysfunction. In human sinoatrial node (SAN), HCN4 is the most abundant of the four isoforms of the HCN family. Tetramers of HCN subunits constitute the ion channels that conduct the hyp...
journal_title:International journal of molecular sciences
pub_type: 杂志文章,评审
doi:10.3390/ijms16023071
更新日期:2015-01-29 00:00:00
abstract::Forty mice were randomly divided into four groups on the basis of the diet to be fed as follows: 5% (low) fat diet (T1: LF); 20% (high) fat diet (T2: HF); 20% fat containing 1% conjugated linoleic acid (CLA) (T3: HFC); and 20% fat containing 1% CLA with 0.5% biopolymers (T4: HFCB). The high-fat with CLA diet groups (H...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms14046848
更新日期:2013-03-26 00:00:00
abstract::Dietary supplementation with polyunsaturated fatty acids (PUFA) n-3 can affect cutaneous wound healing; however, recent findings demonstrate the variable extent of their influence on the quality of healing. Here, we compare the effect of several dietary oils, containing different levels of PUFA n-3 and PUFA n-6, on wo...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms21217911
更新日期:2020-10-24 00:00:00