Abstract:
PURPOSE OF REVIEW:Despite recent advances in the care of patients with advanced non-small cell lung cancer (NSCLC), significant morbidity and mortality remains. Symptoms caused by the cancer and its treatments can be profoundly debilitating. Palliative care aims to reduce this burden. In this review, we discuss the definition, purpose, benefits, and optimal timing of palliative care in advanced NSCLC. RECENT FINDINGS:Several studies evaluating the value of early palliative care for patients with advanced NSCLC and other advanced malignancies have identified benefits for patients, caregivers, and health systems. For patients with advanced NSCLC, introduction of palliative care early in the disease course improves quality of life and even overall survival. Early institution of palliative care should become standard of care for patients with advanced NSCLC.
journal_name
Curr Oncol Repjournal_title
Current oncology reportsauthors
Bhattacharya P,Dessain SK,Evans TLdoi
10.1007/s11912-018-0731-9subject
Has Abstractpub_date
2018-11-09 00:00:00pages
90issue
11eissn
1523-3790issn
1534-6269pii
10.1007/s11912-018-0731-9journal_volume
20pub_type
杂志文章,评审abstract::The RAS-RAF-MEK-ERK pathway is considered to be the most important signal transduction pathway in melanoma, and alterations in this pathway via various genetic mutations, such as BRAF and NRAS mutations, are known to be important drivers of melanomagenesis. As MEK is an essential intermediary kinase protein within thi...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-013-0336-2
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journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-000-0016-x
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journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-004-0024-3
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journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-000-0075-z
更新日期:2000-05-01 00:00:00
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journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-002-0030-2
更新日期:2002-09-01 00:00:00
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journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-012-0270-8
更新日期:2012-12-01 00:00:00
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journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-016-0523-z
更新日期:2016-06-01 00:00:00
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journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-006-0062-0
更新日期:2006-09-01 00:00:00
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journal_title:Current oncology reports
pub_type: 杂志文章,评审
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更新日期:2011-02-01 00:00:00
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journal_title:Current oncology reports
pub_type: 杂志文章,评审
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更新日期:2015-01-01 00:00:00
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journal_title:Current oncology reports
pub_type: 杂志文章,评审
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更新日期:2005-11-01 00:00:00
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journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-013-0361-1
更新日期:2014-01-01 00:00:00
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journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/BF02951428
更新日期:2007-01-01 00:00:00
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journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-008-0064-1
更新日期:2008-09-01 00:00:00
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journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-003-0012-z
更新日期:2003-11-01 00:00:00
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journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-009-0007-5
更新日期:2009-01-01 00:00:00
abstract::The therapeutic landscape for renal cell carcinoma (RCC) has changed drastically over the past several years with the emergence of molecularly targeted therapies. With previous prognostic and predictive tools based on studies of patients treated with cytokine therapies, confirmation of these prior methods and discover...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-009-0015-5
更新日期:2009-03-01 00:00:00
abstract::Cancer risk has become a significant research topic due to an increase in statistical risk models built to predict cancer incidence or mortality. Over the past 3 years, 15 models on the development of different types of cancer, including breast, colorectal, prostate, gastric, lung, ovarian, pancreatic, testicular, and...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-007-0071-7
更新日期:2007-11-01 00:00:00
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journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-007-0011-6
更新日期:2007-03-01 00:00:00
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journal_title:Current oncology reports
pub_type: 杂志文章
doi:10.1007/s11912-006-0045-1
更新日期:2006-03-01 00:00:00
abstract::Skin cancer is the most common type of cancer in the United States. US incidence of malignant melanoma is increasing faster than any other type of cancer. To minimize increasing morbidity and mortality rates, it is imperative that appropriate screening and early detection of skin cancer become more widespread. All phy...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-004-0082-6
更新日期:2004-11-01 00:00:00
abstract:PURPOSE OF REVIEW:Mantle cell lymphoma (MCL) prognosis is strictly related to the characteristics of the disease, which can range from very indolent cases to highly aggressive and refractory ones. Here we will review the current knowledge on MCL biomarkers. RECENT FINDINGS:Biomarker-informed diagnosis is essential for...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-018-0728-4
更新日期:2018-08-22 00:00:00
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journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-018-0693-y
更新日期:2018-04-11 00:00:00
abstract::The search is on for biomarkers for use in the diagnosis, staging, prognosis, and management of patients with melanoma. As with many types of cancer, the hematogenous spread of melanoma is a bad prognostic sign, and many groups have attempted to detect circulating melanoma cells in patients with different stages of me...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-005-0065-2
更新日期:2005-09-01 00:00:00
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journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-019-0821-3
更新日期:2019-06-25 00:00:00
abstract:PURPOSE OF REVIEW:Over the past two decades, advances have been made in understanding the pathophysiology of cancer-associated weight loss, termed "cachexia." To date, there is no proven effective intervention to completely reverse cachexia and there are no approved drug therapies to treat it. This paper will review re...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-019-0765-7
更新日期:2019-02-04 00:00:00
abstract::Pediatric medicine is moving toward a greater appreciation that the delivery of quality medical care involves a partnership including the health care team, the child, and the family. Pediatric medicine now emphasizes the importance of information exchange among these groups. This paper discusses two models for communi...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-007-0061-9
更新日期:2007-11-01 00:00:00
abstract:PURPOSE OF REVIEW:The American Society of Clinical Oncology (ASCO) palliative care recommendations have been updated into a full guideline. Symptom questionnaires-completed and reviewed with patients during care delivery-are poised to play a large role in this guideline because they provide a more comprehensive underst...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-017-0571-z
更新日期:2017-02-01 00:00:00
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journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-006-0070-0
更新日期:2006-11-01 00:00:00
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journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-009-0048-9
更新日期:2009-09-01 00:00:00