Abstract:
:The International Institute of Tropical Agriculture maintains the world's largest collection of cowpea germplasm of over 15,000 accessions. A sub-set of 298 lines from the loosely composed mini core collection of 370 landraces were genotyped based on genotyping by sequencing (GBS). Ward's minimum variance hierarchical cluster analysis, model-based ancestry analysis and discriminant analysis of principal component (DAPC) were carried out on this sub-set. Three clusters were identified by the different clustering methods. Principal component analysis further supported the three clusters especially when accessions are scattered along the axes of the first two principal components. The first two principal components explained a total of 22.30% of the variation. Cluster one comprises 115 accessions from the largest number of countries and has the highest gene diversity, heterozygosity and polymorphic information content (PIC) values. Cluster two is made up of 102 accessions, 90 percent of which are from West and Central Africa. Analysis of molecular variance shows that the most variation is among accessions and lowest among clusters. No cluster is made exclusively of accessions from a single country. Based on SNP markers, the sub set of cowpea mini core germplasm collection used in this study encompasses the diversity in the crop.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Fatokun C,Girma G,Abberton M,Gedil M,Unachukwu N,Oyatomi O,Yusuf M,Rabbi I,Boukar Odoi
10.1038/s41598-018-34555-9subject
Has Abstractpub_date
2018-10-30 00:00:00pages
16035issue
1issn
2045-2322pii
10.1038/s41598-018-34555-9journal_volume
8pub_type
杂志文章abstract::Heteroplasmy is the existence of more than one mitochondrial DNA (mtDNA) variant within a cell. The evolutionary mechanisms of heteroplasmy are not fully understood, despite being a very common phenomenon. Here we combined heteroplasmy measurements using high throughput sequencing on green turtles (Chelonia mydas) wit...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-56918-6
更新日期:2020-01-14 00:00:00
abstract::The systematics of Oriental freshwater mussels (Bivalvia: Unionidae) is poorly known. Here, we present an integrative revision of the genus Trapezoideus Simpson, 1900 to further understanding of freshwater mussel diversity in the region. We demonstrate that Trapezoideus as currently circumscribed is non-monophyletic, ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-39365-1
更新日期:2019-03-11 00:00:00
abstract::Disease associated genetic variations often cause intracellular enzyme inactivation, dysregulation and instability. However, allosteric communication of mutational effects to distant functional sites leading to loss-of-function remains poorly understood. We characterize here interdomain site-to-site communication by w...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep44532
更新日期:2017-03-14 00:00:00
abstract::When faced with adverse environmental conditions, the marsupial Dromiciops gliroides uses either daily or seasonal torpor to support survival and is the only known hibernating mammal in South America. As the sole living representative of the ancient Order Microbiotheria, this species can provide crucial information ab...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep24627
更新日期:2016-04-19 00:00:00
abstract::Although technology has triumphed in facilitating routine genome sequencing, new challenges have been created for the data-analyst. Genome-scale surveys of human variation generate volumes of data that far exceed capabilities for laboratory characterization. By incorporating functional annotations as predictors, stati...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep13373
更新日期:2015-08-24 00:00:00
abstract::Silver nanobelts (AgNBs) have attracted a great interest due to their excellent electrical conductivity and mechanical strength, leading a facile synthesis of these AgNBs in great demand. In here, we are reporting a simple, aqueous phase, size tunable synthesis of smooth surfaced 1D-silver nanobelts using a Polyanilin...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep44796
更新日期:2017-03-20 00:00:00
abstract::Although the demand for high-speed telecommunications has increased in recent years, the performance of transistors fabricated with traditional semiconductors such as silicon, gallium arsenide, and gallium nitride have reached their physical performance limits. Therefore, new materials with high carrier velocities sho...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep03951
更新日期:2014-02-04 00:00:00
abstract::The inhibitory behaviour of non-ionic sugar based N,N'-didodecyl-N,N'-digluconamideethylenediamine gemini surfactant, designated as Glu(12)-2-Glu(12) on mild steel (MS) corrosion in 3.5% NaCl at 30-60 °C was explored using weight loss, PDP, EIS and SEM/EDAX/AFM techniques. The compound inhibited the corrosion of mild ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-21175-6
更新日期:2018-02-27 00:00:00
abstract::The dynamic structure of proteins is essential for their functions and may include large conformational transitions which can be studied by molecular dynamics (MD) simulations. However, details of these transitions are difficult to automatically track. To facilitate their analysis, we developed two scores of correlati...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-72766-1
更新日期:2020-09-28 00:00:00
abstract::Besides lifetime risks, we estimated life expectancy (LE), expected years of life lost (EYLL), lifetime costs, and cost-per-LY (life-year) stratified by different stages of esophageal cancer (EC). From the Taiwan Cancer Registry, we collected 14,420 EC to estimate the incidence rates during 2008-2014. They were follow...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-60701-3
更新日期:2020-02-28 00:00:00
abstract::Chronic fatigue syndrome (CFS) is a persistent and unexplained pathological state characterized by exertional and severely debilitating fatigue, with/without infectious or neuropsychiatric symptoms, lasting at least 6 consecutive months. Its pathogenesis remains incompletely understood. Here, we performed comprehensiv...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep34990
更新日期:2016-10-11 00:00:00
abstract::Herbicide resistance has been observed in Chloris truncata, an Australian native C4 grass and a summer-fallow weed, which is common in no-till agriculture situations where herbicides are involved in crop management. To investigate the role of drought and increased atmospheric carbon dioxide (CO2) in determining weed g...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-47237-x
更新日期:2019-07-24 00:00:00
abstract::Coral reefs face a crisis due to local and global anthropogenic stressors. A large proportion of the ~50% coral loss on the Great Barrier Reef has been attributed to outbreaks of the crown-of-thorns-seastar (COTS). A widely assumed cause of primary COTS outbreaks is increased larval survivorship due to higher food ava...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep08402
更新日期:2015-02-12 00:00:00
abstract::Chronic HIV infection results in impairment of gut-associated lymphoid tissue leading to systemic immune activation. We previously showed that in early SIV-infected rhesus macaques intestinal dysfunction is initiated with the induction of the IL-1β pathway in the small intestine and reversed by treatment with an exoge...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep24723
更新日期:2016-04-22 00:00:00
abstract::Vertical vergence is generally associated with one of three mechanisms: vestibular activation during a head tilt, induced by vertical visual disparity, or as a by-product of ocular torsion. However, vertical vergence can also be induced by seemingly unrelated visual conditions, such as optokinetic rotations. This stud...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-72646-8
更新日期:2020-09-23 00:00:00
abstract::Optical thermometry based on the up-conversion intensity ratio of thermally coupled levels of rare earth ions has been widely studied to achieve an inaccessible temperature measurement in submicron scale. In this work, a novel optical temperature sensing strategy based on the energy transfer from charge transfer bands...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-06421-7
更新日期:2017-07-20 00:00:00
abstract:ABSTARCT:This work explores a new class of vortex/magnetite/iron oxide nanoparticles designed for magnetic hyperthermia applications. These nanoparticles, named Vortex Iron oxide Particles (VIPs), are an alternative to the traditional Superparamagnetic Iron Oxide Nanoparticles (SPIONs), since VIPs present superior heat...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-14633-0
更新日期:2017-11-01 00:00:00
abstract::Cells regulate their intracellular mRNA levels by using specific ribonucleases. Oligoribonuclease (ORN) is a 3'-5' exoribonuclease for small RNA molecules, important in RNA degradation and re-utilisation. However, there is no structural information on the ligand-binding form of ORNs. In this study, the crystal structu...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-39641-0
更新日期:2019-02-25 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-020-58227-9
更新日期:2020-01-24 00:00:00
abstract::To report the efficacy and safety of large diameter scleral lenses and determine their suitability in Asian subjects with intractable ocular surface diseases. This prospective study enrolled intractable ocular surface diseases subjects with uncorrected visual acuity > counting finger but ≥ 0.3 logMAR and best-correcte...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-82010-z
更新日期:2021-01-27 00:00:00
abstract::Recombinant adeno-associated viruses (AAVs) are among the most commonly used vehicles for in vivo gene delivery. However, their tropism is limited, and additionally their efficacy can be negatively affected by prevalence of neutralizing antibodies in sera. Methodologies to systematically engineer AAV capsid properties...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-21742-x
更新日期:2018-02-26 00:00:00
abstract::Cover crops (plants grown in an agricultural rotation between cash crops) can significantly improve soil quality via sequestering carbon, retaining nutrients, decreasing soil erosion, and maintaining belowground biodiversity. However, little is known about the effects of such plants upon soil structure. The aim of the...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-43937-6
更新日期:2019-05-16 00:00:00
abstract::Attending a location in space facilitates responses to targets at that location when the time between cue and target is short. Certain types of exogenous cues - such as sudden peripheral onsets - have been described as reflexive and automatic. Recent studies however, have been showing many cases where exogenous cues a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-31633-w
更新日期:2018-09-05 00:00:00
abstract::In this study we investigated the biological role and mechanism of miR-198 in colorectal carcinoma (CRC). MiR-198 expression was shown to exhibit a strongly negative correlation with lymph node invasion, distant metastasis and patient survival in examinations of colorectal cancer tissues and paired normal colorectal m...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep06145
更新日期:2014-09-01 00:00:00
abstract::In this study, we demonstrate that the lysine methyltransferase G9a inhibits sarcomere organization through regulation of the MEF2C-HDAC5 regulatory axis. Sarcomeres are essential for muscle contractile function. Presently, skeletal muscle disease and dysfunction at the sarcomere level has been associated with mutatio...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep34163
更新日期:2016-09-26 00:00:00
abstract::The distribution of potassium (K+) ions on air-cleaved mica is important in many interfacial phenomena such as crystal growth, self-assembly and charge transfer on mica. However, due to experimental limitations to nondestructively probe single ions and ionic domains, their exact lateral organization is yet unknown. We...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep43451
更新日期:2017-03-06 00:00:00
abstract::Pyrazinamide (PZA) is an important first-line drug in all existing and new tuberculosis (TB) treatment regimens. PZA-resistance in M. tuberculosis is increasing, especially among M/XDR cases. Noted issues with PZA Drug Susceptibility Testing (DST) have driven the search for alternative tests. This study provides a com...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-03452-y
更新日期:2017-06-19 00:00:00
abstract::To identify a vegetation configuration pattern with a high-efficiency purification ability for total nitrogen (TN), available nitrogen (AN), total phosphorous (TP), available phosphorous (AP), and chemical oxygen demand (COD) based on comprehensive assessment results, a water discharge experiment was performed in the ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-38097-y
更新日期:2019-02-20 00:00:00
abstract::The Y chromosome has high genetic variability with low rates of parallel and back mutations, which make up the most informative haplotyping system. To examine whether Y chromosome haplogroups (Y-hgs) could modify the effects of autosomal variants on non-obstructive azoospermia (NOA), based on our previous genome-wide ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep33363
更新日期:2016-09-15 00:00:00
abstract::Investigating cytokines in tear fluid and saliva may offer valuable information for understanding the pathogenesis of primary Sjögren's syndrome (pSS). Cytokine profiles in both tear fluid and saliva of pSS patients, non-Sjögren's syndrome (non-SS) subjects with sicca symptoms, and healthy controls without sicca compl...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-43714-5
更新日期:2019-05-13 00:00:00