Publisher Correction: BATCH-GE: Batch analysis of Next-Generation Sequencing data for genome editing assessment.

abstract：:Impaired wound healing is an immense medical challenge, and while autologous skin grafting remains the "gold-standard" therapeutic option for repairing wounds that cannot be closed by primary or secondary intention, it is limited by substantial donor site morbidity. We previously developed the alternative approach of ...

journal_title：Scientific reports

authors： Fuchs C,Pham L,Henderson J,Stalnaker KJ,Anderson RR,Tam J

更新日期：2021-01-18 00:00:00

abstract：:Statins are well known to have muscle toxicity problem. Herba Cistanches (HC) is a Chinese herb traditionally used for pain in the loins and knees. Our previous in vitro study suggested that it could protect against statin-induced muscle toxicity. However, its in vivo protective effect has never been investigated. The...

journal_title：Scientific reports

authors： Wat E,Ng CF,Koon CM,Zhang C,Gao S,Tomlinson B,Lau CBS

更新日期：2017-08-24 00:00:00

abstract：:Magnetic small-angle neutron scattering (SANS) is a powerful technique for investigating magnetic nanoparticle assemblies in nonmagnetic matrices. For such microstructures, the standard theory of magnetic SANS assumes uniformly magnetized nanoparticles (macrospin model). However, there exist many experimental and theo...

journal_title：Scientific reports

authors： Vivas LG,Yanes R,Michels A

更新日期：2017-10-12 00:00:00

abstract：:Enhanced carotid body (CB) chemoreflex function is strongly related to cardiorespiratory disorders and disease progression in heart failure (HF). The mechanisms underlying CB sensitization during HF are not fully understood, however previous work indicates blood flow per se can affect CB function. Then, we hypothesize...

journal_title：Scientific reports

authors： Del Rio R,Andrade DC,Toledo C,Diaz HS,Lucero C,Arce-Alvarez A,Marcus NJ,Schultz HD

更新日期：2017-08-14 00:00:00

abstract：:Solid state memory and switching devices aimed at replacing the flash memory technology operate by switching from the high to low resistance when conductive filaments are created in response to the electric pulse. The filaments are identified with either structurally different protrusions or purely electronic conducti...

journal_title：Scientific reports

authors： Karpov VG,Niraula D

更新日期：2018-08-15 00:00:00

abstract：:We report the development of on-chip fluorescence switching system based on DNA strand displacement and DNA hybridization for the construction of a rewritable and randomly accessible data storage device. In this study, the feasibility and potential effectiveness of our proposed system was evaluated with a series of we...

journal_title：Scientific reports

authors： Nguyen HH,Park J,Hwang S,Kwon OS,Lee CS,Shin YB,Ha TH,Kim M

更新日期：2018-01-10 00:00:00

abstract：:The PDZ domain-containing scaffold protein, syntenin-1, binds to the transmembrane proteoglycan, syndecan-4, but the molecular mechanism/function of this interaction are unknown. Crystal structure analysis of syntenin-1/syndecan-4 cytoplasmic domains revealed that syntenin-1 forms a symmetrical pair of dimers anchored...

journal_title：Scientific reports

authors： Choi Y,Yun JH,Yoo J,Lee I,Kim H,Son HN,Kim IS,Yoon HS,Zimmermann P,Couchman JR,Cho HS,Oh ES,Lee W

更新日期：2016-11-10 00:00:00

abstract：:Lipases are interfacially activated enzymes that catalyze the hydrolysis of ester bonds and constitute prime candidates for industrial and biotechnological applications ranging from detergent industry, to chiral organic synthesis. As a result, there is an incentive to understand the mechanisms underlying lipase activi...

journal_title：Scientific reports

authors： Bohr SS,Lund PM,Kallenbach AS,Pinholt H,Thomsen J,Iversen L,Svendsen A,Christensen SM,Hatzakis NS

更新日期：2019-11-07 00:00:00

abstract：:Imputation is a computational method based on the principle of haplotype sharing allowing enrichment of genome-wide association study datasets. It depends on the haplotype structure of the population and density of the genotype data. The 1000 Genomes Project led to the generation of imputation reference panels which h...

journal_title：Scientific reports

authors： Ahmad M,Sinha A,Ghosh S,Kumar V,Davila S,Yajnik CS,Chandak GR

更新日期：2017-07-27 00:00:00

abstract：:Cryptochromes (CRYs) are an ubiquitously occurring class of photoreceptors, which are important for regulating the circadian rhythm of animals via a time-delayed transcription-translation feedback loop (TTFL). Due to their protein architecture and common FAD chromophore, they belong to the same superfamily as photolya...

journal_title：Scientific reports

authors： Franz-Badur S,Penner A,Straß S,von Horsten S,Linne U,Essen LO

更新日期：2019-07-09 00:00:00

abstract：:A compact analysis platform for detecting liquid absorption and emission spectra using a set of optical linear variable filters atop a CMOS image sensor is presented. The working spectral range of the analysis platform can be extended without a reduction in spectral resolution by utilizing multiple linear variable fil...

journal_title：Scientific reports

authors： Wan Y,Carlson JA,Kesler BA,Peng W,Su P,Al-Mulla SA,Lim SJ,Smith AM,Dallesasse JM,Cunningham BT

更新日期：2016-07-08 00:00:00

abstract：:Many environmental flow (e-flow) studies and applications have predominantly used state-(i.e., at a single time point) and rate-(i.e., temporal change) based demographic characteristics of species representing lower trophic levels (e.g., fish communities) to build flow-ecology relationships, rather than using a proces...

journal_title：Scientific reports

authors： Paudel S,Koprowski JL,Thakuri U,Sigdel R,Gautam RC

更新日期：2020-12-18 00:00:00

abstract：:Leprosy remains persistently endemic in several low- or middle income countries. Transmission is still ongoing as indicated by the unabated rate of leprosy new case detection, illustrating the insufficiency of current prevention methods. Therefore, low-complexity tools suitable for large scale screening efforts to spe...

journal_title：Scientific reports

authors： van Hooij A,Tjon Kon Fat EM,Batista da Silva M,Carvalho Bouth R,Cunha Messias AC,Gobbo AR,Lema T,Bobosha K,Li J,Weng X,Salgado CG,Spencer JS,Corstjens PLAM,Geluk A

更新日期：2018-12-18 00:00:00

abstract：:Genetic divergences among mammalian strains are presented phenotypically in various aspects of physical appearance such as body shape and facial features. Yet how genetic diversity is expressed in brain function still remains unclear. Functional connectivity has been shown to be a valuable approach in characterizing t...

journal_title：Scientific reports

authors： Huang SM,Wu YL,Peng SL,Peng HH,Huang TY,Ho KC,Wang FN

更新日期：2016-02-22 00:00:00

abstract：:Some herbivore-induced-plant volatiles (HIPVs) compounds are vital for the functioning of an ecosystem, by triggering multi-trophic interactions for natural enemies, plants and herbivores. However, the effect of these chemicals, which play a crucial role in regulating the multi-trophic interactions between plant-herbi...

journal_title：Scientific reports

authors： Lin Y,Qasim M,Hussain M,Akutse KS,Avery PB,Dash CK,Wang L

更新日期：2017-01-12 00:00:00

abstract：:In the era of precision medicine the treatment options for cancer patients and subsequent outcomes are expected to improve. We present a review of patients enrolled in first-in-human Phase1 trials at University of Alabama at Birmingham. Between 1/2015-6/2017, 162 cancer patients (whole cohort, WC) were enrolled on pha...

journal_title：Scientific reports

authors： Paluri RK,Li P,Anderson A,Nandagopal L,McArdle T,Young M,Robert F,Naik G,Saleh M

更新日期：2020-05-13 00:00:00

abstract：:We investigated the effect of a new Rho kinase inhibitor, SB772077B (SB77) on aqueous outflow facility (OF) in human eyes using human organ-cultured anterior segment (HOCAS). IOP was monitored for 24 h post-treatment with either SB77 (0.1/10/50 µM) or vehicle after a stable baseline pressure. The hydrodynamic pattern ...

journal_title：Scientific reports

authors： Ashwinbalaji S,Senthilkumari S,Gowripriya C,Krishnadas S,Gabelt BAT,Kaufman PL,Muthukkaruppan V

更新日期：2018-10-19 00:00:00

abstract：:Ontogenetic information is crucial to understand life histories and represents a true challenge in dinosaurs due to the scarcity of growth series available. Mussaurus patagonicus was a sauropodomorph dinosaur close to the origin of Sauropoda known from hatchling, juvenile and mature specimens, providing a sufficiently...

journal_title：Scientific reports

authors： Otero A,Cuff AR,Allen V,Sumner-Rooney L,Pol D,Hutchinson JR

更新日期：2019-05-20 00:00:00

abstract：:Although thimerosal, an ethylmercury-based preservative, has been removed from most pediatric vaccines in the United States, some multidose vaccines, such as influenza vaccines, still contain thimerosal. Considering that a growing number of studies indicate involvement of the gut microbiome in infant immune developmen...

journal_title：Scientific reports

authors： Hasegawa Y,Curtis B,Yutuc V,Rulien M,Morrisroe K,Watkins K,Ferrier C,English C,Hewitson L,Slupsky CM

更新日期：2018-10-26 00:00:00

abstract：:Music and language are complex hierarchical systems in which individual elements are systematically combined to form larger, syntactic structures. Suggestions that music and language share syntactic processing resources have relied on evidence that syntactic violations in music interfere with syntactic processing in l...

journal_title：Scientific reports

authors： Fiveash A,McArthur G,Thompson WF

更新日期：2018-12-17 00:00:00

abstract：:Fusarium Head Blight (FHB) caused by Fusarium graminearum pathogens constitutes a major threat to agricultural production because it frequently reduces the yield and quality of the crop. The disease severity is predicted to increase in various regions owing to climate change. Integrated management where biocontrol pla...

journal_title：Scientific reports

authors： Timmusk S,Copolovici D,Copolovici L,Teder T,Nevo E,Behers L

更新日期：2019-01-24 00:00:00

abstract：:Chemotherapy (CTx)-induced premature ovarian failure (POF) in woman remains clinically irreversible. Amniotic fluid stem cells (AFSCs) have shown the potential to treat CTx-induced POF; however, the underlying mechanism is unclear. Here we demonstrate that AFSC-derived exosomes recapitulate the anti-apoptotic effect o...

journal_title：Scientific reports

authors： Xiao GY,Cheng CC,Chiang YS,Cheng WT,Liu IH,Wu SC

更新日期：2016-03-16 00:00:00

abstract：:The Y-box proteins are multifunctional nucleic acid-binding proteins involved in various aspects of gene regulation. The founding member of the Y-box protein family, YB-1, functions as a transcription factor as well as a principal component of messenger ribonucleoprotein particles (mRNPs) in somatic cells. The nuclear...

journal_title：Scientific reports

authors： Matsumoto K,Kose S,Kuwahara I,Yoshimura M,Imamoto N,Yoshida M

更新日期：2018-04-18 00:00:00

abstract：:Norfloxacin (NOF) is an environmentally harmful and ubiquitous aquatic pollutant with extensive production and application. In this study, a novel composition named carbon-based composite photocatalytic material of zinc oxide and zinc sulphide (ZnO/ZnS@BC) was successfully obtained by the impregnation-roasting method ...

journal_title：Scientific reports

authors： Liu W,He T,Wang Y,Ning G,Xu Z,Chen X,Hu X,Wu Y,Zhao Y

更新日期：2020-07-17 00:00:00

abstract：:Marek's disease virus (MDV) is a preferred vector in the construction of recombinant vaccines. However, bivalent vaccine based on MDV that confers full protection against both very virulent Marek's and infectious bursal disease virus (IBDV) infections in chickens has not been produced. Here we developed a system utili...

journal_title：Scientific reports

authors： Li K,Liu Y,Liu C,Gao L,Zhang Y,Cui H,Gao Y,Qi X,Zhong L,Wang X

更新日期：2016-12-16 00:00:00

abstract：:Strenuous exercise increases circulating cell free DNA (cfDNA) and stimulates blood phagocytes to generate reactive oxygen species (ROS) which may induce DNA strand breaks. We tested whether: (A) elevated cfDNA in response to three repeated bouts of exhaustive exercise has decreased integrity; (B) each bout of exercis...

journal_title：Scientific reports

authors： Stawski R,Walczak K,Perdas E,Wlodarczyk A,Sarniak A,Kosielski P,Meissner P,Budlewski T,Padula G,Nowak D

更新日期：2019-11-04 00:00:00

abstract：:Development of tissue engineering scaffolds with native-like biology and microarchitectures is a prerequisite for stem cell mediated generation of off-the-shelf-tissues. So far, the field of tissue engineering has not full-filled its grand potential of engineering such combinatorial scaffolds for engineering functiona...

journal_title：Scientific reports

authors： Guermani E,Shaki H,Mohanty S,Mehrali M,Arpanaei A,Gaharwar AK,Dolatshahi-Pirouz A

更新日期：2016-07-28 00:00:00

abstract：:The binding of metal ions at the interface of protein complexes presents a unique and poorly understood mechanism of molecular assembly. A remarkable example is the Rad50 zinc hook domain, which is highly conserved and facilitates the Zn2+-mediated homodimerization of Rad50 proteins. Here, we present a detailed analys...

journal_title：Scientific reports

authors： Kochańczyk T,Nowakowski M,Wojewska D,Kocyła A,Ejchart A,Koźmiński W,Krężel A

更新日期：2016-11-03 00:00:00

abstract：:There is an urgent need for sensors deployed during focal therapies to inform treatment planning and in vivo monitoring in thin tissues. Specifically, the measurement of thermal properties, cooling surface contact, tissue thickness, blood flow and phase change with mm to sub mm accuracy are needed. As a proof of princ...

journal_title：Scientific reports

authors： Natesan H,Hodges W,Choi J,Lubner S,Dames C,Bischof J

更新日期：2016-02-26 00:00:00

abstract：:This research investigated the association between prolonged disposable diaper (DD) wearing in infancy and primary enuresis (PNE). As a case-control study, we collected data from 376 children with enuresis and 379 healthy children who were sex- and age-matched at three tertiary care institutions in mainland China from...

journal_title：Scientific reports

authors： Li X,Wen JG,Shen T,Yang XQ,Peng SX,Wang XZ,Xie H,Wu XD,Du YK

更新日期：2020-09-01 00:00:00