Identification of Salt Stress Responding Genes Using Transcriptome Analysis in Green Alga Chlamydomonas reinhardtii.

Abstract:

:Salinity is one of the most important abiotic stresses threatening plant growth and agricultural productivity worldwide. In green alga Chlamydomonas reinhardtii, physiological evidence indicates that saline stress increases intracellular peroxide levels and inhibits photosynthetic-electron flow. However, understanding the genetic underpinnings of salt-responding traits in plantae remains a daunting challenge. In this study, the transcriptome analysis of short-term acclimation to salt stress (200 mM NaCl for 24 h) was performed in C. reinhardtii. A total of 10,635 unigenes were identified as being differently expressed by RNA-seq, including 5920 up- and 4715 down-regulated unigenes. A series of molecular cues were screened for salt stress response, including maintaining the lipid homeostasis by regulating phosphatidic acid, acetate being used as an alternative source of energy for solving impairment of photosynthesis, and enhancement of glycolysis metabolism to decrease the carbohydrate accumulation in cells. Our results may help understand the molecular and genetic underpinnings of salt stress responses in green alga C. reinhardtii.

journal_name

Int J Mol Sci

authors

Wang N,Qian Z,Luo M,Fan S,Zhang X,Zhang L

doi

10.3390/ijms19113359

subject

Has Abstract

pub_date

2018-10-26 00:00:00

issue

11

issn

1422-0067

pii

ijms19113359

journal_volume

19

pub_type

杂志文章
  • The Role of the RNA-RNA Interactome in the Hepatitis C Virus Life Cycle.

    abstract::RNA virus genomes are multifunctional entities endowed with conserved structural elements that control translation, replication and encapsidation, among other processes. The preservation of these structural RNA elements constraints the genomic sequence variability. The hepatitis C virus (HCV) genome is a positive, sin...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章,评审

    doi:10.3390/ijms21041479

    authors: Romero-López C,Berzal-Herranz A

    更新日期:2020-02-21 00:00:00

  • T-Tubular Electrical Defects Contribute to Blunted β-Adrenergic Response in Heart Failure.

    abstract::Alterations of the β-adrenergic signalling, structural remodelling, and electrical failure of T-tubules are hallmarks of heart failure (HF). Here, we assess the effect of β-adrenoceptor activation on local Ca(2+) release in electrically coupled and uncoupled T-tubules in ventricular myocytes from HF rats. We employ an...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms17091471

    authors: Crocini C,Coppini R,Ferrantini C,Yan P,Loew LM,Poggesi C,Cerbai E,Pavone FS,Sacconi L

    更新日期:2016-09-03 00:00:00

  • Small Noncoding RNA Signatures for Determining the Developmental Potential of an Embryo at the Morula Stage.

    abstract::As part of the optimization of assisted reproductive technology programs, the aim of the study was to identify key small noncoding RNA (sncRNA) molecules that participate in maternal-to-zygotic transition and determine development potential and competence to form a healthy fetus. Small RNA deep sequencing followed by ...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms21249399

    authors: Timofeeva A,Drapkina Y,Fedorov I,Chagovets V,Makarova N,Shamina M,Kalinina E,Sukhikh G

    更新日期:2020-12-10 00:00:00

  • High-Dimensional descriptor selection and computational QSAR modeling for antitumor activity of ARC-111 analogues Based on Support Vector Regression (SVR).

    abstract::To design ARC-111 analogues with improved efficiency, we constructed the QSAR of 22 ARC-111 analogues with RPMI8402 tumor cells. First, the optimized support vector regression (SVR) model based on the literature descriptors and the worst descriptor elimination multi-roundly (WDEM) method had similar generalization as ...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms13011161

    authors: Zhou W,Dai Z,Chen Y,Wang H,Yuan Z

    更新日期:2012-01-01 00:00:00

  • Exposure to diflubenzuron results in an up-regulation of a chitin synthase 1 gene in citrus red mite, Panonychus citri (Acari: Tetranychidae).

    abstract::Chitin synthase synthesizes chitin, which is critical for the arthropod exoskeleton. In this study, we cloned the cDNA sequences of a chitin synthase 1 gene, PcCHS1, in the citrus red mite, Panonychus citri (McGregor), which is one of the most economically important pests of citrus worldwide. The full-length cDNA of P...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms15033711

    authors: Xia WK,Ding TB,Niu JZ,Liao CY,Zhong R,Yang WJ,Liu B,Dou W,Wang JJ

    更新日期:2014-02-28 00:00:00

  • The Molecular Mechanism of Perillaldehyde Inducing Cell Death in Aspergillus flavus by Inhibiting Energy Metabolism Revealed by Transcriptome Sequencing.

    abstract::Perillaldehyde (PAE), an essential oil in Perilla plants, serves as a safe flavor ingredient in foods, and shows an effectively antifungal activity. Reactive oxygen species (ROS) accumulation in Aspergillus flavus plays a critical role in initiating a metacaspase-dependent apoptosis. However, the reason for ROS accumu...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms21041518

    authors: Pan C,Li YX,Yang K,Famous E,Ma Y,He X,Geng Q,Liu M,Tian J

    更新日期:2020-02-23 00:00:00

  • Lattice strain due to an atomic vacancy.

    abstract::Volumetric strain can be divided into two parts: strain due to bond distance change and strain due to vacancy sources and sinks. In this paper, efforts are focused on studying the atomic lattice strain due to a vacancy in an FCC metal lattice with molecular dynamics simulation (MDS). The result has been compared with ...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms10062798

    authors: Li S,Sellers MS,Basaran C,Schultz AJ,Kofke DA

    更新日期:2009-06-19 00:00:00

  • Analysis of Hypericin-Mediated Effects and Implications for Targeted Photodynamic Therapy.

    abstract::The phototoxic effect of hypericin can be utilized for Photodynamic Therapy (PDT) of cancer. After intravenous application and systemic distribution of the drug in the patient's body, the tumor site is exposed to light. Subsequently, toxic reactive oxygen species (ROS) are generated, inducing tumor cell death. To prev...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms18071388

    authors: Mühleisen L,Alev M,Unterweger H,Subatzus D,Pöttler M,Friedrich RP,Alexiou C,Janko C

    更新日期:2017-06-29 00:00:00

  • Restraint Stress in Mice Alters Set of 25 miRNAs Which Regulate Stress- and Depression-Related mRNAs.

    abstract::In the present study, we aim to identify the effect of restrain stress (RS) on the expression of miRNAs in mouse serum. We used three genotypes of animals (mice with knock-out of the gene-encoding norepinephrine transporter, NET-KO; C57BL/6J, and SWR/J) which had previously been shown to display different sensitivity ...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms21249469

    authors: Solich J,Kuśmider M,Faron-Górecka A,Pabian P,Dziedzicka-Wasylewska M

    更新日期:2020-12-12 00:00:00

  • Overexpression of the Stress-Inducible SsMAX2 Promotes Drought and Salt Resistance via the Regulation of Redox Homeostasis in Arabidopsis.

    abstract::Recent studies have demonstrated that strigolactones (SLs) also participate in the regulation of stress adaptation; however, the regulatory mechanism remains elusive. In this study, the homolog of More Axillary Branches 2, which encodes a key component in SL signaling, in the perennial oil plant Sapium sebiferum was i...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms20040837

    authors: Wang Q,Ni J,Shah F,Liu W,Wang D,Yao Y,Hu H,Huang S,Hou J,Fu S,Wu L

    更新日期:2019-02-15 00:00:00

  • Isolation and characterization of 21 microsatellite loci in Cardiocrinum giganteum var. yunnanense (Liliaceae), an important economic plant in China.

    abstract::Twenty-one microsatellite markers from the genome of Cardiocrinum giganteum var. yunnanense, an important economic plant in China, were developed with a fast isolation protocol by amplified fragment length polymorphism of sequences containing repeats (FIASCO). Polymorphism within each locus was assessed in 24 wild ind...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms13021437

    authors: Li R,Yang J,Yang J,Dao Z

    更新日期:2012-01-01 00:00:00

  • Spontaneous Mutations in HIV-1 Gag, Protease, RT p66 in the First Replication Cycle and How They Appear: Insights from an In Vitro Assay on Mutation Rates and Types.

    abstract::While drug resistant mutations in HIV-1 are largely credited to its error prone HIV-1 RT, the time point in the infection cycle that these mutations can arise and if they appear spontaneously without selection pressures both remained enigmatic. Many HIV-1 RT mutational in vitro studies utilized reporter genes (LacZ) a...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms22010370

    authors: Yeo JY,Koh DW,Yap P,Goh GR,Gan SK

    更新日期:2020-12-31 00:00:00

  • Nucleated polymerisation in the presence of pre-formed seed filaments.

    abstract::We revisit the classical problem of nucleated polymerisation and derive a range of exact results describing polymerisation in systems intermediate between the well-known limiting cases of a reaction starting from purely soluble material and for a reaction where no new growth nuclei are formed. ...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms12095844

    authors: Cohen SI,Vendruscolo M,Dobson CM,Knowles TP

    更新日期:2011-01-01 00:00:00

  • Wheat Transcription Factor TaSNAC11-4B Positively Regulates Leaf Senescence through Promoting ROS Production in Transgenic Arabidopsis.

    abstract::Senescence is the final stage of leaf development which is accompanied by highly coordinated and complicated reprogramming of gene expression. Genetic manipulation of leaf senescence in major crops including wheat has been shown to be able to increase stress tolerance and grain yield. NAC(No apical meristem (NAM), ATA...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms21207672

    authors: Zhang Z,Liu C,Guo Y

    更新日期:2020-10-16 00:00:00

  • Using Proteomics to Understand How Leishmania Parasites Survive inside the Host and Establish Infection.

    abstract::Leishmania is a protozoan parasite that causes a wide range of different clinical manifestations in mammalian hosts. It is a major public health risk on different continents and represents one of the most important neglected diseases. Due to the high toxicity of the drugs currently used, and in the light of increasing...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章,评审

    doi:10.3390/ijms17081270

    authors: Veras PS,Bezerra de Menezes JP

    更新日期:2016-08-19 00:00:00

  • The First Report of Polymorphisms and Genetic Features of the prion-like Protein Gene (PRND) in a Prion Disease-Resistant Animal, Dog.

    abstract::Prion disease has displayed large infection host ranges among several species; however, dogs have not been reported to be infected and are considered prion disease-resistant animals. Case-controlled studies in several species, including humans and cattle, indicated a potent association of prion protein gene (PRNP) pol...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms20061404

    authors: Won SY,Kim YC,Kim K,Kim AD,Jeong BH

    更新日期:2019-03-20 00:00:00

  • Linking Pesticide Exposure with Pediatric Leukemia: Potential Underlying Mechanisms.

    abstract::Leukemia is the most common cancer in children, representing 30% of all childhood cancers. The disease arises from recurrent genetic insults that block differentiation of hematopoietic stem and/or progenitor cells (HSPCs) and drives uncontrolled proliferation and survival of the differentiation-blocked clone. Pediatri...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章,评审

    doi:10.3390/ijms17040461

    authors: Hernández AF,Menéndez P

    更新日期:2016-03-29 00:00:00

  • A Systematic Review of Neuroprotective Strategies in the Management of Hypoglycemia.

    abstract::Severe hypogylcemia has been found to induce cerebral damage. While a number of illnesses can lead to hypoglycemic episodes, antidiabetic medications prescribed for glycemic control are a common cause. Considering the rising prevalence of diabetes mellitus in the population, we investigated neuroprotective strategies ...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms20030550

    authors: Nistor M,Schmidt M,Graul I,Rakers F,Schiffner R

    更新日期:2019-01-28 00:00:00

  • Modulation of Disordered Proteins with a Focus on Neurodegenerative Diseases and Other Pathologies.

    abstract::Intrinsically disordered proteins (IDPs) do not have rigid 3D structures, showing changes in their folding depending on the environment or ligands. Intrinsically disordered proteins are widely spread in eukaryotic genomes, and these proteins participate in many cell regulatory metabolism processes. Some IDPs, when abe...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章,评审

    doi:10.3390/ijms20061322

    authors: Martinelli AHS,Lopes FC,John EBO,Carlini CR,Ligabue-Braun R

    更新日期:2019-03-15 00:00:00

  • New Therapeutic Implications of Endothelial Nitric Oxide Synthase (eNOS) Function/Dysfunction in Cardiovascular Disease.

    abstract::The Global Burden of Disease Study identified cardiovascular risk factors as leading causes of global deaths and life years lost. Endothelial dysfunction represents a pathomechanism that is associated with most of these risk factors and stressors, and represents an early (subclinical) marker/predictor of atheroscleros...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章,评审

    doi:10.3390/ijms20010187

    authors: Daiber A,Xia N,Steven S,Oelze M,Hanf A,Kröller-Schön S,Münzel T,Li H

    更新日期:2019-01-07 00:00:00

  • In Search for the Membrane Regulators of Archaea.

    abstract::Membrane regulators such as sterols and hopanoids play a major role in the physiological and physicochemical adaptation of the different plasmic membranes in Eukarya and Bacteria. They are key to the functionalization and the spatialization of the membrane, and therefore indispensable for the cell cycle. No archaeon h...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章,评审

    doi:10.3390/ijms20184434

    authors: Salvador-Castell M,Tourte M,Oger PM

    更新日期:2019-09-09 00:00:00

  • Comparative molecular dynamics simulations of mitogen-activated protein kinase-activated protein kinase 5.

    abstract::The mitogen-activated protein kinase-activated protein kinase MK5 is a substrate of the mitogen-activated protein kinases p38, ERK3 and ERK4. Cell culture and animal studies have demonstrated that MK5 is involved in tumour suppression and promotion, embryogenesis, anxiety, cell motility and cell cycle regulation. In t...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms15034878

    authors: Lindin I,Wuxiuer Y,Ravna AW,Moens U,Sylte I

    更新日期:2014-03-19 00:00:00

  • How Oxygen Availability Affects the Antimicrobial Efficacy of Host Defense Peptides: Lessons Learned from Studying the Copper-Binding Peptides Piscidins 1 and 3.

    abstract::The development of new therapeutic options against Clostridioides difficile (C. difficile) infection is a critical public health concern, as the causative bacterium is highly resistant to multiple classes of antibiotics. Antimicrobial host-defense peptides (HDPs) are highly effective at simultaneously modulating the i...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms20215289

    authors: Oludiran A,Courson DS,Stuart MD,Radwan AR,Poutsma JC,Cotten ML,Purcell EB

    更新日期:2019-10-24 00:00:00

  • The Convergence of the Hedgehog/Intein Fold in Different Protein Splicing Mechanisms.

    abstract::Protein splicing catalyzed by inteins utilizes many different combinations of amino-acid types at active sites. Inteins have been classified into three classes based on their characteristic sequences. We investigated the structural basis of the protein splicing mechanism of class 3 inteins by determining crystal struc...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms21218367

    authors: Beyer HM,Virtanen SI,Aranko AS,Mikula KM,Lountos GT,Wlodawer A,Ollila OHS,Iwaï H

    更新日期:2020-11-07 00:00:00

  • Behavior of Gingival Fibroblasts on Titanium Implant Surfaces in Combination with either Injectable-PRF or PRP.

    abstract::Various strategies have been employed to speed tissue regeneration using bioactive molecules. Interestingly, platelet concentrates derived from a patient's own blood have been utilized as a regenerative strategy in recent years. In the present study, a novel liquid platelet formulation prepared without the use of anti...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms18020331

    authors: Wang X,Zhang Y,Choukroun J,Ghanaati S,Miron RJ

    更新日期:2017-02-04 00:00:00

  • Astrocytoma: A Hormone-Sensitive Tumor?

    abstract::Astrocytomas and, in particular, their most severe form, glioblastoma, are the most aggressive primary brain tumors and those with the poorest vital prognosis. Standard treatment only slightly improves patient survival. Therefore, new therapies are needed. Very few risk factors have been clearly identified but many ep...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章,评审

    doi:10.3390/ijms21239114

    authors: Hirtz A,Rech F,Dubois-Pot-Schneider H,Dumond H

    更新日期:2020-11-30 00:00:00

  • Novel Peptide-Based Inhibitors for Microtubule Polymerization in Phytophthora capsici.

    abstract::The plant disease Phytophthora blight, caused by the oomycete pathogen Phytophthora capsici, is responsible for major economic losses in pepper production. Microtubules have been an attractive target for many antifungal agents as they are involved in key cellular events such as cell proliferation, signaling, and migra...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms20112641

    authors: Lee SC,Kim SH,Hoffmeister RA,Yoon MY,Kim SK

    更新日期:2019-05-29 00:00:00

  • Mitochondrial Carriers for Aspartate, Glutamate and Other Amino Acids: A Review.

    abstract::Members of the mitochondrial carrier (MC) protein family transport various molecules across the mitochondrial inner membrane to interlink steps of metabolic pathways and biochemical processes that take place in different compartments; i.e., are localized partly inside and outside the mitochondrial matrix. MC substrate...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章,评审

    doi:10.3390/ijms20184456

    authors: Monné M,Vozza A,Lasorsa FM,Porcelli V,Palmieri F

    更新日期:2019-09-10 00:00:00

  • New Insight into the Octamer of TYMS Stabilized by Intermolecular Cys43-Disulfide.

    abstract::Thymidylate synthase (TYMS) is an essential enzyme for the de novo synthesis of deoxythymidine monophosphate (dTMP) and has been a primary target for cancer chemotherapy. Although the physical structure of TYMS and the molecular mechanisms of TYMS catalyzing the conversion of deoxyuridine monophosphate (dUMP) to dTMP ...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms19051393

    authors: Xie D,Wang L,Xiao Q,Wu X,Zhang L,Yang Q,Wang L

    更新日期:2018-05-07 00:00:00

  • Membrane Topological Model of Glycosyltransferases of the GT-C Superfamily.

    abstract::Glycosyltransferases that use polyisoprenol-linked donor substrates are categorized in the GT-C superfamily. In eukaryotes, they act in the endoplasmic reticulum (ER) lumen and are involved in N-glycosylation, glypiation, O-mannosylation, and C-mannosylation of proteins. We generated a membrane topology model of C-man...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms20194842

    authors: Albuquerque-Wendt A,Hütte HJ,Buettner FFR,Routier FH,Bakker H

    更新日期:2019-09-29 00:00:00