Abstract：
OBJECTS:Understanding the neural basis underlying Internet gaming disorder (IGD) is essential for the diagnosis and treatment of this type of behavioural addiction. Aberrant resting-state functional connectivity (rsFC) of the default mode network (DMN) has been reported in individuals with IGD. Since rsFC is not a directional analysis, the effective connectivity within the DMN in IGD remains unclear. Here, we employed spectral dynamic causal modeling (spDCM) to explore this issue. METHODS:Resting state fMRI data were collected from 64 IGD (age: 22.6 ± 2.2) and 63 well-matched recreational Internet game users (RGU, age: 23.1 ± 2.5). Voxel-based mean time series data extracted from the 4 brain regions within the DMN (medial prefrontal cortex, mPFC; posterior cingulate cortex, PCC; bilateral inferior parietal lobule, left IPL/right IPL) of two groups during the resting state were used for the spDCM analysis. RESULTS:Compared with RGU, IGD showed reduced effective connectivity from the mPFC to the PCC and from the left IPL to the mPFC, with reduced self-connection in the PCC and the left IPL. CONCLUSIONS:The spDCM could distinguish the changes in the functional architecture between two groups more precisely than rsFC. Our findings suggest that the decreased excitatory connectivity from the mPFC to the PCC may be a crucial biomarker for IGD. Future brain-based intervention should pay attention to dysregulation in the IPL-mPFC-PCC circuits.
journal_name
Addict Behavjournal_title
Addictive behaviorsauthors
Wang M,Zheng H,Du X,Dong Gdoi
10.1016/j.addbeh.2018.10.019subject
Has Abstractpub_date
2019-03-01 00:00:00pages
62-70eissn
0306-4603issn
1873-6327pii
S0306-4603(18)30907-9journal_volume
90pub_type
杂志文章abstract：:It has been proposed that internal, stable, and global attributions for the cause of a lapse following a period of abstinence and concomitant feelings of guilt and loss of control increased the probability of a return to regular substance use. The Abstinence Violation Effect (AVE) hypotheses were tested in a sample of...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/0306-4603(94)90048-5
更新日期：1994-01-01 00:00:00
abstract：:Alcohol and marijuana misuse is prevalent on many university campuses, with high rates of undergraduate students reporting experiencing alcohol and/or marijuana-related problems, which have been consistently associated with coping-motivated use. While previous studies have found dispositional mindfulness to be negativ...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2020.106554
更新日期：2020-12-01 00:00:00
abstract：:The purpose of this study was to identify individual and social/environmental predictors of alcohol and drug use 2 years following substance abuse treatment. Participants (n=180) self-administered questionnaires within their first month of substance abuse treatment and completed a 2-year follow-up interview. Individua...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/s0306-4603(01)00284-2
更新日期：2003-06-01 00:00:00
abstract：:The attitudes, beliefs and expectations of the addict have received surprisingly little research attention. The present study looks at the relationship between the addict's perception of their own drug taking and their behaviour in treatment. The subjects who took part in the study were receiving treatment at a London...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/0306-4603(82)90044-2
更新日期：1982-01-01 00:00:00
abstract：:This article reviews the 61 alcohol treatment outcome studies published from 1989-1993 with respect to methodology. Although better assessment of subjects' pretreatment characteristics was noted, a minority of studies met even the basic requirements of experimental studies. Further, some reversals of methodological pr...
journal_title：Addictive behaviors
pub_type： 杂志文章,评审
doi：10.1016/s0306-4603(95)00109-3
更新日期：1997-03-01 00:00:00
abstract：:Peer influence and peer selection have both been linked to the smoking behavior of adolescents. The present investigation uses social network analysis methodology to explore the simultaneous effects of both processes on adolescent smoking and smoking susceptibility over two time periods. Results suggest the effects of...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2007.04.008
更新日期：2007-12-01 00:00:00
abstract：:Retrospective studies of military personnel and survivors of community disasters suggest a link between traumatic exposure and substance use. This is the first study to investigate this association prospectively in a military population. A representative cohort of members of the UK Armed Forces was recruited into a lo...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2008.03.010
更新日期：2008-08-01 00:00:00
abstract：:A two-year primary prevention program for junior high school students was evaluated. The program consisted of drug education, "alternatives," and affective in- service training for the students' teachers. Students in one junior high school received the intervention and students in another school served as a no-treatme...
journal_title：Addictive behaviors
pub_type： 临床试验,杂志文章
doi：10.1016/0306-4603(83)90040-0
更新日期：1983-01-01 00:00:00
abstract：:Previous studies have found that smoking is a strong factor that increases peripheral blood CD4+ T lymphocytes. However, most studies did not assess the cumulative long-life exposure of smoking on differential lymphocyte populations. In this study, to clarify the association of smoking habits and circulating lymphocyt...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2006.11.007
更新日期：2007-07-01 00:00:00
abstract：INTRODUCTION:Parental monitoring and family relations are recognized as protective factors for youth alcohol use. The purpose of this study was to investigate perceived parental monitoring and family relations among subgroups of Mexican youths with different patterns of drinking behaviors and consequences. METHODS:A l...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2015.07.025
更新日期：2015-12-01 00:00:00
abstract：:Individuals at high risk for alcoholism have been hypothesized to acquire alcoholic characteristics more rapidly than those at low risk. Two studies examined reactivity to alcohol cues, a phenomenon linked to craving for alcohol in clinical alcoholics, and ad lib drinking behavior in young men at varying risk for alco...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/0306-4603(90)90005-i
更新日期：1990-01-01 00:00:00
abstract：:Research shows that there has been a substantial increase in substance use and abuse during the COVID-19 pandemic, and that substance use/abuse is a commonly reported way of coping with anxiety concerning COVID-19. Anxiety about COVID-19 is more than simply worry about infection. Research provides evidence of a COVID ...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2020.106754
更新日期：2021-03-01 00:00:00
abstract：INTRODUCTION:Problematic alcohol use is highly comorbid with posttraumatic stress disorder (PTSD), and prior work has demonstrated that individuals with PTSD may self-medicate with alcohol in an effort to reduce their symptoms. The combination of impulsivity and alcohol-related expectancies influences the development o...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2014.09.022
更新日期：2015-02-01 00:00:00
abstract：:Treatment for drug use, like the process by which a person comes to use illicit drugs, may be seen to be at least in part a psychosocial process involving emotional, cognitive, and relationship domains. Treatment programs attempt to improve the psychosocial functioning of clients with the ultimate goal of effecting ch...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/0306-4603(95)00098-4
更新日期：1996-09-01 00:00:00
abstract：:Initial sensitivity to the pharmacological effects of a drug may affect patterns of future use and dependence for a wide variety of drugs. Retrospective reports of sensations experienced upon early experimentation, however, may be limited by recall bias based on time elapsed and subsequent experiences. To validate rep...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2004.08.001
更新日期：2005-03-01 00:00:00
abstract：:The aim of the study was to examine psychometric properties of the PUN screening test concerning illicit drug problem use by adolescents. The criterion standard for the test's validity was a diagnostic interview conducted by trained specialists. Respondents were reached by snowball sampling in 58 randomly chosen Polis...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2006.06.004
更新日期：2007-03-01 00:00:00
abstract：:The purpose of this systematic review and meta-analysis was to investigate the effects of transcranial direct current stimulation (tDCS) on symptoms of nicotine dependence in treatment-seeking smokers. Twelve studies qualified for this meta-analysis, and we used 15 total comparisons from the included studies for the d...
journal_title：Addictive behaviors
pub_type： 杂志文章,meta分析
doi：10.1016/j.addbeh.2019.05.006
更新日期：2019-09-01 00:00:00
abstract：BACKGROUND:US opioid overdose deaths continue to climb, with a 12.0% increase from 2016 to 2017. Fentanyl, a synthetic opioid, has been a major contributor to opioid-related overdose deaths. While fentanyl-related overdose is driven by illicit fentanyl, little is known about individuals who misuse prescription fentanyl...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2019.04.022
更新日期：2019-09-01 00:00:00
abstract：:This study investigates the association linking truancy and drug-related experiences among adolescents surveyed via a street outreach program. A total of 2126 adolescents aged 12 to 18 years recruited from Taipei street sites completed a self-administered anonymous questionnaire. The lifetime prevalence of illicit dru...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2005.04.011
更新日期：2006-01-01 00:00:00
abstract：:Most investigators have not adequately accounted for the alcohol content of different beverages when assessing alcohol consumption. Considerable research has assessed consumption in terms of the number of standard drinks. A problem with standard drink measures is that different distilled spirits, wines, and malt bever...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/0306-4603(91)90064-o
更新日期：1991-01-01 00:00:00
abstract：:The commodity model of social support and features of Nondirective Support may clarify varied results of support interventions for smoking cessation. A commodity model views social support as attractive in and of itself and as an alternative to high-risk choices such as smoking. If such support is easily accessible, a...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/s0306-4603(97)00064-6
更新日期：1997-11-01 00:00:00
abstract：:This study aims to assess which types of social influence are correlated with young people's (15-24 years) heavy drinking (six or more glasses) in public drinking places during the weekend. Drinking in public drinking places can be defined as a "timeout" situation. Therefore we assumed that situational factors (e.g., ...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/0306-4603(95)00052-6
更新日期：1996-03-01 00:00:00
abstract：:This study assessed how many months of pretreatment drinking data would represent a stable baseline. Fifty-one couples were interviewed using the time-line follow-back interviewing procedure to obtain 365 days of pretreatment drinking data. The pattern (binge, episodic, steady) and frequency of drinking did not differ...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/0306-4603(84)90031-5
更新日期：1984-01-01 00:00:00
abstract：INTRODUCTION:There has been a recent decrease in population level alcohol consumption in Australia, particularly in young people. Whether this is due to increasing abstinence or a shift in the way people think about alcohol is not known. The aim of this study is to investigate trends in self-identification of drinker t...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2016.12.002
更新日期：2017-04-01 00:00:00
abstract：:To investigate the role of treatment modality in relapse prevention treatment, 32 cocaine-dependent subjects were randomly assigned by cohorts to group-based relapse prevention (G-RP) or individually based RP (I-RP). The two RP formats were identical in content, consisting of 12 outpatient treatment sessions over a 2-...
journal_title：Addictive behaviors
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0306-4603(96)00047-0
更新日期：1997-05-01 00:00:00
abstract：PURPOSE:Adolescents susceptible to late-onset smoking (becoming regular smokers at age 18 or later) are an understudied population. Social support is a promising target for intervention, but it is important to distinguish between implicit social support (reminders that one belongs to a network of valued others) and exp...
journal_title：Addictive behaviors
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.addbeh.2016.06.017
更新日期：2016-11-01 00:00:00
abstract：BACKGROUND:Previous studies have reported positive associations between cannabis use and mental health problems. However, it has not been possible to draw a definitive conclusion regarding the causal direction between cannabis use and impaired mental health. This study aimed at examining possible associations between c...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2016.03.005
更新日期：2016-08-01 00:00:00
abstract：:The main purpose of this study was to test the relationship between past-year suicide attempt (SA) and past-year opioid misuse among Veterans at high risk of suicide who reported using at least one illicit substance or alcohol in the past year. Baseline data from 130 high suicide-risk Veterans (n = 39 past-year opioid...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2019.106064
更新日期：2019-12-01 00:00:00
abstract：BACKGROUND:Opioid agonist therapy (OAT) models are generally provided without consideration of how pre-treatment characteristics may be associated with outcome. Therefore, we aimed to first characterize longitudinal trajectories of opioid use before initiating OAT. Then we explored the impact of OAT on opioid use acros...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2020.106655
更新日期：2021-01-01 00:00:00
abstract：:The majority of young adults who use alcohol and marijuana sometimes use the two substances simultaneously. Understanding why young adults engage in simultaneous alcohol and marijuana (SAM) use may inform interventions and help offset negative consequences. To date, research has not yet examined motives for SAM use. T...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2017.08.027
更新日期：2018-01-01 00:00:00
