Abstract：
:In the present work, Dioscorea opposita Thunb polysaccharide-zinc (DPS-zinc) inclusion complex was synthesized for the first time and its anti-diabetes activities against Streptozotocin (STZ)-induced diabetic rats were assayed. The detail structural and morphological analysis of as-prepared DPS-zinc complex was done by using different spectroscopic and microscopic methods. The pharmacological study revealed that DPS-zinc presented a potent hypoglycemic effect on STZ-induced diabetic rats, decreased the glucose and insulin levels, reduced malondialdehyde (MDA) contents and increased SOD and T-AOC activities significantly in liver. The levels of T-CHO, TG and LDL-C in serum were dramatically decreased while HDL-C level was increased with the treatment of proposed inclusion complex. In brief, DPS-zinc could be considered as a potential candidate for developing an ingredient of functional foods for zinc supplements with the hypoglycemic action.
journal_name
Int J Biol Macromoljournal_title
International journal of biological macromoleculesauthors
Zhang Y,Khan MZH,Yuan T,Zhang Y,Liu X,Du Z,Zhao Ydoi
10.1016/j.ijbiomac.2018.10.068subject
Has Abstractpub_date
2019-01-01 00:00:00pages
1029-1036eissn
0141-8130issn
1879-0003pii
S0141-8130(18)33934-5journal_volume
121pub_type
杂志文章abstract：:Basa acellular dermal matrix (BADM) has advantages in the preparation of oral prosthetic membranes. In order to prepare high-quality BADM, a suitable cross-linking agent is necessary. In this study, acellular dermal matrix was prepared from basa fish skin and then cross-linked with carbodiimide (EDC), oxidized chitosa...
journal_title：International journal of biological macromolecules
pub_type： 杂志文章
doi：10.1016/j.ijbiomac.2020.07.019
更新日期：2020-12-01 00:00:00
abstract：:In this study some physicochemical properties and elemental analysis of Prunus avium gum exudates were investigated. The gum studied had, on average, 75.14% carbohydrate, 11.3% uronic acids, 1.11% protein, 7.53% moisture content (w.b.) and 3.12% ash. Measured values for the angle of repose, Carr's index and Hausner ra...
journal_title：International journal of biological macromolecules
pub_type： 杂志文章
doi：10.1016/j.ijbiomac.2016.08.070
更新日期：2016-12-01 00:00:00
abstract：:Owing to the excellent cyto-compatibility of silk fibroin (SF) and the simple fabrication of nano-fibrous webs, electro-spun SF webs have attracted much research attention in numerous biomedical fields. Because the production rate of electro-spun webs is strongly dependent on the electro-spinning rate used, the electr...
journal_title：International journal of biological macromolecules
pub_type： 杂志文章
doi：10.1016/j.ijbiomac.2016.11.026
更新日期：2017-02-01 00:00:00
abstract：:To improve the hydrophobicity and thermoplastic processability of starch, lactic acid esterified starch (LA-e-starch) was prepared by in-situ solid phase esterification with corn starch as the raw material and LA as the esterifying agent. Fourier transform infrared spectroscopy confirmed that the esterification reacti...
journal_title：International journal of biological macromolecules
pub_type： 杂志文章
doi：10.1016/j.ijbiomac.2019.11.171
更新日期：2020-08-01 00:00:00
abstract：:Ultraviolet radiation, an effective sterilizing source, rapidly kills the causative organism (Mycobacterium leprae) of leprosy. But, the reasons behind this quick death are not clearly understood. Also, the impact of UV radiation on the antigen(s) which is/are responsible for the survival of this pathogen is still unk...
journal_title：International journal of biological macromolecules
pub_type： 杂志文章
doi：10.1016/j.ijbiomac.2018.07.151
更新日期：2018-11-01 00:00:00
abstract：:Sterilization of milk protein without heating is of great interest. Gamma irradiation is a very powerful method to decontaminated casein. Gamma-irradiation of proteins in aqueous media at doses higher than 5kGy is known to induce their aggregation (without oxygen) or degradation (in presence of oxygen). Camellia sinen...
journal_title：International journal of biological macromolecules
pub_type： 杂志文章
doi：10.1016/j.ijbiomac.2011.01.003
更新日期：2011-04-01 00:00:00
abstract：:Impacts of hot water extraction (HWE), pressurized water extraction (PWE), high-speed shearing homogenization extraction, microwave assisted extraction (MAE), ultrasound assisted extraction (UAE), ultrasound assisted enzymatic extraction, and ultrasound-microwave assisted extraction (UMAE) on physicochemical character...
journal_title：International journal of biological macromolecules
pub_type： 杂志文章
doi：10.1016/j.ijbiomac.2019.12.273
更新日期：2020-03-01 00:00:00
abstract：:The objective of the present work is to study the physicochemical and functional properties of taro starch (Colocasia esculenta) and to further modify the starch by treating with citric acid to obtain a novel functional material. DSC, FTIR and SEM studies were performed along with physicochemical analysis. The disinte...
journal_title：International journal of biological macromolecules
pub_type： 杂志文章
doi：10.1016/j.ijbiomac.2018.06.086
更新日期：2018-10-15 00:00:00
abstract：:Telomeric guanine-rich sequence can adopt quadruplex structures that are important for their biological role in chromosomal stabilisation. G quartets are characterised by the cyclic hydrogen bonding of four guanine bases in a coplanar arrangement and their stability is ion-dependent. In this work we compare the stabil...
journal_title：International journal of biological macromolecules
pub_type： 杂志文章
doi：10.1016/s0141-8130(02)00073-9
更新日期：2003-01-15 00:00:00
abstract：:Graft Copolymer resulting from polymerization of acrylic acid from chitosan is non-coherent, brittle and exhibit modest swelling in water, which limits its application. Chitosan-cellulose hybrid was initially prepared and novel polymeric ligand ((CTS/Cell)-g-PAA) derived from grafting polymerization of acrylic acid fr...
journal_title：International journal of biological macromolecules
pub_type： 杂志文章
doi：10.1016/j.ijbiomac.2018.05.062
更新日期：2018-09-01 00:00:00
abstract：:In the present study, the results from thermogravimetric analysis (TGA), contact angle measurements, tensile tests, scanning electron microscopy (SEM) and atomic force microscopy (AFM) of polymer composites containing chitosan (Ch) and montmorillonite (MMT) with and without poly(vinyl alcohol) (PVA) are presented. Mea...
journal_title：International journal of biological macromolecules
pub_type： 杂志文章
doi：10.1016/j.ijbiomac.2015.08.003
更新日期：2015-11-01 00:00:00
abstract：:The present study was performed to investigate the chemical composition and antioxidant activity of glycoprotein purified from Undaria pinnatifida Harvey (UPGP). On SDS-PAGE, UPGP migrated as a single band with a molecular weight of approximately 10 kDa and confirmed by staining with Schiff's reagent as glycoprotein. ...
journal_title：International journal of biological macromolecules
pub_type： 杂志文章
doi：10.1016/j.ijbiomac.2013.09.009
更新日期：2013-11-01 00:00:00
abstract：:There are several families of cysteine proteinases with different folds - for example the (chymo)trypsin fold family and papain-like fold family - but in both families the hydrolase activity of cysteine proteinases requires a cysteine residue as the catalytic nucleophile. In this work, we have analyzed the topology of...
journal_title：International journal of biological macromolecules
pub_type： 杂志文章
doi：10.1016/j.ijbiomac.2020.10.022
更新日期：2020-12-15 00:00:00
abstract：:The aim of this study was to fabricate a novel bilayer scaffold containing cellulose nanofiber/poly (vinyl) alcohol (CNF/PVA) to evaluate its potential use in skin tissue engineering. Here, the scaffolds were fabricated using a novel one-step freeze-drying technique with two different concentrations of the aforementio...
journal_title：International journal of biological macromolecules
pub_type： 杂志文章
doi：10.1016/j.ijbiomac.2019.06.104
更新日期：2019-09-01 00:00:00
abstract：:The corynemycolyltransferase proteins were identified from Corynebacterium glutamicum and Corynebacterium efficiens genomes using computational tools available in the public domain. Three-dimensional models were constructed for corynemycolyltransferases based on the crystal structures of related mycolyltransferases in...
journal_title：International journal of biological macromolecules
pub_type： 杂志文章
doi：10.1016/j.ijbiomac.2004.03.008
更新日期：2004-06-01 00:00:00
abstract：:This work studied the effect of preparation conditions for electrospun fiber mats of Thai silk fibroin/type B gelatin (SF/GB) for controlled release applications. The increasing in applied voltage resulted in decreased average fiber size and narrow fiber size distribution. An increasing in silk fibroin content in blen...
journal_title：International journal of biological macromolecules
pub_type： 杂志文章
doi：10.1016/j.ijbiomac.2010.02.008
更新日期：2010-06-01 00:00:00
abstract：:Amygdalin, despite possessing anticancerous properties, has been viewed as a controversial choice due to the presence of the cyanide group. Here, we synthesise and investigate the potential of alginate-chitosan nanoparticles (ACNPs) as drug delivery agents for amygdalin encapsulation and its delivery to cancer cells. ...
journal_title：International journal of biological macromolecules
pub_type： 杂志文章
doi：10.1016/j.ijbiomac.2020.02.191
更新日期：2020-06-15 00:00:00
abstract：:Bacterial cellulose (BC) has emerged as a biomaterial for diverse biomedical applications owing to its unique structural, physico-chemical, mechanical, and biological features. Its porous geometry and three-dimensional fibrous structure allow the impregnation of various materials into its matrix. The current study was...
journal_title：International journal of biological macromolecules
pub_type： 杂志文章
doi：10.1016/j.ijbiomac.2019.07.050
更新日期：2019-09-15 00:00:00
abstract：:This study aims to investigate the neuroprotective effects of Coptis chinensis Franch polysaccharide (CCP) on Aβ1-42 transgenic CL4176 Caenorhabditis elegans, as well as its mechanism of action. The results in life span experiment showed that CCP could significantly increase the lifespan of C. elegans and the effect i...
journal_title：International journal of biological macromolecules
pub_type： 杂志文章
doi：10.1016/j.ijbiomac.2018.03.035
更新日期：2018-07-01 00:00:00
abstract：:Here, we investigated the effect of preparation temperature and alginate-coating on L929 fibroblast behavior on lyophilized microporous PLLA/PLGA (95:5, w/w) scaffolds. The lower freezing temperature used during lyophilization (-80 °C) resulted in smaller pores (around 50 μm) and higher compressive modulus (1500 kPa) ...
journal_title：International journal of biological macromolecules
pub_type： 杂志文章
doi：10.1016/j.ijbiomac.2018.11.169
更新日期：2019-03-01 00:00:00
abstract：:Bone tissue engineering holds great promise and clinical efficacy for the regeneration of bone defects. In this study, an amphoteric N,O-carboxymethyl chitosan (NOCC) and fucoidan (FD) were covalently cross-linked via an amidation reaction to synthesize NOCC/FD composite hydrogels. The hydrogels were lyophilized and t...
journal_title：International journal of biological macromolecules
pub_type： 杂志文章
doi：10.1016/j.ijbiomac.2018.08.179
更新日期：2018-12-01 00:00:00
abstract：:The Publisher regrets that this article is an accidental duplication of an article that has already been published in Int. J. Biol. Macromol, doi:10.1016/j.ijbiomac.2008.07.012. The duplicate article has therefore been withdrawn. ...
journal_title：International journal of biological macromolecules
pub_type： 杂志文章
doi：10.1016/j.ijbiomac.2008.08.002
更新日期：2008-08-19 00:00:00
abstract：:A novel approach in fabricating anionic inter-polymeric complex polysaccharide bio-platform with enhanced mechanical, structural and chemical properties for burn wound dressings. This approach implies a facile, insitu method to design soft nano-floral inter-polymeric complexes. In particular, sodium alginate (SA) and ...
journal_title：International journal of biological macromolecules
pub_type： 杂志文章
doi：10.1016/j.ijbiomac.2020.04.157
更新日期：2020-08-15 00:00:00
abstract：:Osteochondral (OC) lesions can occur in the knee and ankle. Such lesions induce a fracture in the cartilage protecting the bone joints. Cartilage tissue shows limited self-regeneration ability, hence the tissue is avascular and lack of vascular innervation, while the bone is a unique organ with the capacity to self-re...
journal_title：International journal of biological macromolecules
pub_type： 杂志文章
doi：10.1016/j.ijbiomac.2020.01.191
更新日期：2020-04-15 00:00:00
abstract：:The study of drug-DNA interactions is of great importance, as it paves the way towards the design of better therapeutic agents. Here, the interaction of DNA with a therapeutic and prophylactic drug citral has been studied. We have attempted to ascertain the mode of binding of citral with calf thymus DNA (Ct-DNA) throu...
journal_title：International journal of biological macromolecules
pub_type： 杂志文章
doi：10.1016/j.ijbiomac.2018.02.098
更新日期：2018-07-01 00:00:00
abstract：:Soybean straw cannot be efficiently degraded and utilized by ruminants due to the complex cross-linked structure among cellulose, hemicellulose, and lignin in its cell wall. Xylanase can degrade the xylan component of hemicellulose, destroy the xylan-lignin matrix and, consequently, would theoretically improve the hyd...
journal_title：International journal of biological macromolecules
pub_type： 杂志文章
doi：10.1016/j.ijbiomac.2020.02.187
更新日期：2020-05-15 00:00:00
abstract：:It is well accepted that porphyrins related to heme, are effectively able to act as pharmaceutical. For instance, they were found to interfere with the aggregation of beta-amyloid peptide. In present study, the influence of heme concentration on the amyloid-type aggregation of ovalbumin was investigated. We provided e...
journal_title：International journal of biological macromolecules
pub_type： 杂志文章
doi：10.1016/j.ijbiomac.2008.10.011
更新日期：2009-01-01 00:00:00
abstract：:This study investigated the impact of citric acid modification combined with alcoholic-alkaline treatment on physicochemical, textural and rheological properties of sorghum and corn starches. Both starches were modified with citric acid (CA) using concentrations (20 and 40%) w/w and were named as SCA and CCA, respecti...
journal_title：International journal of biological macromolecules
pub_type： 杂志文章
doi：10.1016/j.ijbiomac.2019.10.143
更新日期：2020-05-01 00:00:00
abstract：:In this study, the cells-free and cells-loaded chitosan hydrochloride-alginate (CHC-Alg) microcapsules were firstly fabricated with polyelectrolyte complexes via an orifice-polymerization method. Scanning electron microscope images showed that the CHC-Alg microcapsules had a typical shell-core structure and the model ...
journal_title：International journal of biological macromolecules
pub_type： 杂志文章
doi：10.1016/j.ijbiomac.2016.09.034
更新日期：2016-12-01 00:00:00
abstract：:Potato tuber starch was genetically engineered in the plant by the simultaneous antisense suppression of the starch branching enzyme (SBE) I and II isoforms. Starch prepared from 12 independent lines and three control lines were characterised with respect to structural and physical properties. The lengths of the amylo...
journal_title：International journal of biological macromolecules
pub_type： 杂志文章
doi：10.1016/j.ijbiomac.2005.05.006
更新日期：2005-08-01 00:00:00
