Abstract:
:In plants, environmental conditions such as temperature affect survival, growth, and fitness, particularly during key stages such as seedling growth and reproduction. To survive and thrive in changing conditions, plants have evolved adaptive responses that tightly regulate developmental processes such as hypocotyl elongation and flowering time in response to environmental temperature changes. Increases in temperature, coupled with increasing fluctuations in local climate and weather, severely affect our agricultural systems; therefore, understanding the mechanisms by which plants perceive and respond to temperature is critical for agricultural sustainability. In this review, we summarize recent findings on the molecular mechanisms of ambient temperature perception as well as possible temperature sensing components in plants. Based on recent publications, we highlight several temperature response mechanisms, including the deposition and eviction of histone variants, DNA methylation, alternative splicing, protein degradation, and protein localization. We discuss roles of each proposed temperature-sensing mechanism that affects plant development, with an emphasis on flowering time. Studies of plant ambient temperature responses are advancing rapidly, and this review provides insights for future research aimed at understanding the mechanisms of temperature perception and responses in plants.
journal_name
Int J Mol Scijournal_title
International journal of molecular sciencesauthors
Susila H,Nasim Z,Ahn JHdoi
10.3390/ijms19103196subject
Has Abstractpub_date
2018-10-16 00:00:00issue
10issn
1422-0067pii
ijms19103196journal_volume
19pub_type
杂志文章,评审abstract::Malondialdehyde (MAA) within a lipid pathway has been demonstrated to possess an important role in endothelial function that undergoes periodontitis and coronary heart disease (CHD) development. This study evaluated the impact of periodontitis, CHD, or a combination of both diseases (periodontitis + CHD) on salivary a...
journal_title:International journal of molecular sciences
pub_type: 临床试验,杂志文章
doi:10.3390/ijms20236061
更新日期:2019-12-01 00:00:00
abstract::Psoriasis vulgaris is an immune-mediated inflammatory skin disease. Although acitretin is a widely used synthetic retinoid for moderate to severe psoriasis, little is known about patients' genetics in response to this drug. In this study, 179 patients were enrolled in either the discovery set (13 patients) or replicat...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms18020295
更新日期:2017-01-29 00:00:00
abstract::The paper studies the combined effects of beta-emitting radionuclide tritium and Humic Substances (HS) on the marine unicellular microorganism-luminous bacteria-under conditions of low-dose radiation exposures (<0.04 Gy). Tritium was used as a component of tritiated water. Bacterial luminescence intensity was consider...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms21186783
更新日期:2020-09-16 00:00:00
abstract::Chronic inflammation in adipose tissue may contribute to depot-specific adipose tissue expansion, leading to obesity and insulin resistance. Dietary supplementation with quercetin or botanical extracts containing quercetin attenuates high fat diet (HFD)-induced obesity and insulin resistance and decreases inflammation...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms19030895
更新日期:2018-03-17 00:00:00
abstract::Increased plasma homocysteinemia is considered a risk factor of dementia, including Alzheimer's disease (AD) and vascular dementia. However, the reason elevated plasma homocysteinemia increases the risk of dementia remains unknown. A pathological hallmark of AD is neurofibrillary tangles (NFTs) that consist of patholo...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms19030891
更新日期:2018-03-17 00:00:00
abstract::Genomic actions of estrogens in vertebrates are exerted via two intracellular estrogen receptor (ER) subtypes, ERα and ERβ, which show cell- and tissue-specific expression profiles. Mammalian immune cells express ERs and are responsive to estrogens. More recently, evidence became available that ERs are also present in...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms19040932
更新日期:2018-03-21 00:00:00
abstract::Parathyroid hormone-related protein (PTHrP), with isoforms ranging from 139 to 173 amino acids, has long been implicated in the development and regulation of multiple tissues, including that of the skeleton, via paracrine and autocrine signaling. PTHrP is also known as a potent mediator of cancer-induced bone disease,...
journal_title:International journal of molecular sciences
pub_type: 杂志文章,评审
doi:10.3390/ijms20112814
更新日期:2019-06-08 00:00:00
abstract::Weight regulation and the magnitude of weight loss after a Roux-en-Y gastric bypass (RYGB) can be genetically determined. DNA methylation patterns and the expression of some genes can be altered after weight loss interventions, including RYGB. The present study aimed to evaluate how the gene expression and DNA methyla...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms21124476
更新日期:2020-06-24 00:00:00
abstract::Death associated protein kinase (DAPK) is a calcium/calmodulin-regulated serine/threonine kinase; its main function is to regulate cell death. DAPK family proteins consist of DAPK1, DAPK2, DAPK3, DAPK-related apoptosis-inducing protein kinases (DRAK)-1 and DRAK-2. In this review, we discuss the roles and regulatory me...
journal_title:International journal of molecular sciences
pub_type: 杂志文章,评审
doi:10.3390/ijms19103031
更新日期:2018-10-04 00:00:00
abstract::Alterations to the programmed cell death protein-1 (PD-1) pathway were previously shown to be involved in a poorer prognosis for patients with proliferative glomerulonephritis (PGN). Here, we investigated the association between several infectious agents and the expression of PD-1 and its ligand (PD-L1) on T and B lym...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms21218001
更新日期:2020-10-27 00:00:00
abstract::Osteoporosis is characterized by a reduction of the bone mineral density (BMD) and microarchitectural deterioration of the bone, which lead to bone fragility and susceptibility to fracture. Astaxanthin (AST) has a variety of biological activities, such as a protective effect against asthma or neuroinflammation, antiox...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms19030912
更新日期:2018-03-19 00:00:00
abstract::Polyglutamine diseases, including Huntington's disease and a number of spinocerebellar ataxias, are caused by expanded CAG repeats that are located in translated sequences of individual, functionally-unrelated genes. Only mutant proteins containing polyglutamine expansions have long been thought to be pathogenic, but ...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms160818741
更新日期:2015-08-11 00:00:00
abstract::Microglia are the resident immune cells of the central nervous system (CNS) and participate in physiological and pathological processes. Their unique developmental nature suggests age-dependent structural and functional impairments that might contribute to neurodegenerative diseases. In the present study, we addressed...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms19030706
更新日期:2018-03-01 00:00:00
abstract::Saturated aqueous solutions of various common salts were examined for their effect on aqueous aldol reactions catalysted by a highly active C(2)-symmetric diprolinamide organocatalyst developed in our laboratory. With respect to the aldol reaction between cyclohexanone and 4-nitrobenzaldehyde, deionised water was alwa...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms12129083
更新日期:2011-01-01 00:00:00
abstract::Aqueous solutions of ethoxylated alcohols which form lyotropic liquid crystals at high concentrations (40-80%) were selected as model lubricating substances. Microscopic studies under polarized light and viscosity measurements were carried out in order to confirm the presence of liquid crystalline structures in the ca...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms11010189
更新日期:2010-01-12 00:00:00
abstract::Even though advancement in medicine has contributed to the control of many diseases to date, cancer therapy continues to pose several challenges. Hepatocellular carcinoma (HCC) etiology is multifactorial. Recently, non-alcoholic fatty liver disease (NAFLD) has been considered as an important risk factor of HCC. NAFLD ...
journal_title:International journal of molecular sciences
pub_type: 杂志文章,评审
doi:10.3390/ijms21175999
更新日期:2020-08-20 00:00:00
abstract::A specific oligodeoxynucleotide (ODN), ODN MT01, was found to have positive effects on the proliferation and activation of the osteoblast-like cell line MG 63. In this study, the detailed signaling pathways in which ODN MT01 promoted the differentiation of osteoblasts were systematically examined. ODN MT01 enhanced th...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms13077902
更新日期:2012-01-01 00:00:00
abstract::Ten articles published in the "Special Issue: Salicylic Acid Signalling in Plants" are summarized, in order to get a global picture about the mode of action of salicylic acid in plants, and about its interaction with other stress-signalling routes. Its ecological aspects and possible practical use are also discussed. ...
journal_title:International journal of molecular sciences
pub_type: 社论
doi:10.3390/ijms21072655
更新日期:2020-04-10 00:00:00
abstract::Strigolactones (SLs), a group of plant hormones, induce germination of root-parasitic plants and inhibit shoot branching in many plants. Shoot branching is an important trait that affects the number and quality of flowers and fruits. Root-parasitic plants, such as Phelipanche spp., infect tomato roots and cause econom...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms19092645
更新日期:2018-09-06 00:00:00
abstract::Laser induced opening of the C(60) cage is studied by a semiclassical electron-radiation-ion dynamics technique. The simulation results indicate that the C(60) cage is abruptly opened immediately after laser excitation. The opening of the C(60) cage induces a quick increase in kinetic energy and a sharp decrease in el...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms12010353
更新日期:2011-01-13 00:00:00
abstract::Background: Chronic skin wounds are a growing financial burden for healthcare providers, causing discomfort/immobility to patients. Whilst animal chronic wound models have been developed to allow for mechanistic studies and to develop/test potential therapies, such systems are not good representations of the human chr...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms19041001
更新日期:2018-03-27 00:00:00
abstract::We herein review available computational and experimental data pointing to the abundance of structural disorder within the nucleoprotein (N) and phosphoprotein (P) from three paramyxoviruses, namely the measles (MeV), Nipah (NiV) and Hendra (HeV) viruses. We provide a detailed molecular description of the mechanisms g...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms160715688
更新日期:2015-07-10 00:00:00
abstract::Busulfan is an alkylating agent routinely used in conditioning regimens prior to allogeneic hematopoietic cell transplantation (HCT) for various nonmalignant disorders, including inborn errors of metabolism. The combination of model-based dosing and therapeutic drug monitoring (TDM) of busulfan pharmacokinetics (PK) t...
journal_title:International journal of molecular sciences
pub_type:
doi:10.3390/ijms21165634
更新日期:2020-08-06 00:00:00
abstract::Acute liver failure (ALF) leads to neurological symptoms defined as hepatic encephalopathy (HE). Although accumulation of ammonia and neuroinflammation are generally accepted as main contributors to HE pathomechanism, a buildup of bile acids (BA) in the blood is a frequent component of liver injury in HE patients. Rec...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms21207750
更新日期:2020-10-20 00:00:00
abstract::RNA interference (RNAi) has emerged as a powerful tool for studying target identification and holds promise for the development of therapeutic gene silencing. Recent advances in RNAi delivery and target selection provide remarkable opportunities for translational medical research. The induction of RNAi relies on small...
journal_title:International journal of molecular sciences
pub_type: 杂志文章,评审
doi:10.3390/ijms16035254
更新日期:2015-03-06 00:00:00
abstract::Current outcome prediction markers for localized prostate cancer (PCa) are insufficient. The impact of the lipid-modifying Sphingomyelin Phosphodiesterase Acid Like 3B (SMPDL3B) in PCa is unknown. Two cohorts of patients with PCa who underwent radical prostatectomy (n = 40, n = 56) and benign prostate hyperplasia (BPH...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms21124373
更新日期:2020-06-19 00:00:00
abstract::Sperm cryopreservation and artificial insemination are important methods for giant panda breeding and preservation of extant genetic diversity. Lower conception rates limit the use of artificial insemination with frozen-thawed giant panda sperm, due to the lack of understanding of the cryodamaging or cryoinjuring mech...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms19103066
更新日期:2018-10-08 00:00:00
abstract::The emergence of multidrug-resistant bacteria is a major global health concern. The search for new therapies has brought bacteriophages into the spotlight, and new phages are being described as possible therapeutic agents. Among the bacteria that are most extensively resistant to current antibiotics is Klebsiella pneu...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms21093160
更新日期:2020-04-30 00:00:00
abstract::Magnetic resonance spectroscopy (MRS) is a non-invasive method for quantitative estimation of liver fat. Knowledge of its imprecision, which comprises biological variability and measurement error, is required to design therapeutic trials with measurement of change. The role of adipocyte lipolysis in ectopic fat accumu...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms17071089
更新日期:2016-07-08 00:00:00
abstract::S-equol is a major bacterial metabolite of the soy isoflavone daidzein. It is known to be a phytoestrogen that acts by binding to the nuclear estrogen receptors (ERs) that are expressed in various brain regions, including the cerebellum. However, the effects of S-equol on cerebellar development and function have not y...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms20205178
更新日期:2019-10-18 00:00:00