Genes Contributing to Domestication of Rice Seed Traits and Its Global Expansion.

abstract：:Transcriptional reprograming after the exposure of plants to elevated temperatures is a hallmark of stress response which is required for the manifestation of thermotolerance. Central transcription factors regulate the stress survival and recovery mechanisms and many of the core responses controlled by these factors a...

journal_title：Genes

authors： Hu Y,Fragkostefanakis S,Schleiff E,Simm S

更新日期：2020-06-16 00:00:00

abstract：:RabGTPase activating proteins (RabGAP) are responsible for directing the deactivation of vesicular trafficking master regulators associated to plant development, the RabGTPase proteins. Recently, RabGAPs were identified in Arabidopsis and rice, but studies were not yet reported in tomato. Herein, we identified 24 RabG...

journal_title：Genes

authors： Madrid-Espinoza J,Salinas-Cornejo J,Ruiz-Lara S

更新日期：2019-08-23 00:00:00

abstract：:Gene doping, an activity which abuses and misuses gene therapy, is a major concern in sports and horseracing industries. Effective methods capable of detecting and monitoring gene doping are urgently needed. Although several PCR-based methods that detect transgenes have been developed, many of them focus only on a sin...

journal_title：Genes

authors： Tozaki T,Ohnuma A,Kikuchi M,Ishige T,Kakoi H,Hirota KI,Kusano K,Nagata SI

更新日期：2020-04-23 00:00:00

abstract：:Since ancient times, the importance of physical activity (PA) and of a wholesome diet for human health has been clearly recognized. However, only recently, it has been acknowledged that PA can reverse at least some of the unwanted effects of a sedentary lifestyle, contributing to the treatment of pathologies such as h...

journal_title：Genes

authors： Di Liegro I

更新日期：2019-12-16 00:00:00

abstract：:Candida albicans mutants deficient in homologous recombination (HR) are extremely sensitive to the alkylating agent methyl-methane-sulfonate (MMS). Here, we have investigated the role of HR genes in the protection and repair of C. albicans chromosomes by taking advantage of the heat-labile property (55 °C) of MMS-indu...

journal_title：Genes

authors： Ciudad T,Bellido A,Andaluz E,Hermosa B,Larriba G

更新日期：2018-09-07 00:00:00

abstract：:A large number of studies have focused on identifying molecular biomarkers, including microRNAs (miRNAs) to aid in the diagnosis and prognosis of the most common subtypes of non-Hodgkin lymphoma (NHL), Diffuse Large B-cell Lymphoma and Follicular Lymphoma. NHL is difficult to diagnose and treat with many cases becomin...

journal_title：Genes

authors： Bradshaw G,Sutherland HG,Haupt LM,Griffiths LR

更新日期：2016-12-17 00:00:00

abstract：:Individual cells in an organism are variable, which strongly impacts cellular processes. Advances in sequencing technologies have enabled single-cell genomic analysis to become widespread, addressing shortcomings of analyses conducted on populations of bulk cells. While the field of single-cell plant genomics is in it...

journal_title：Genes

authors： Yuan Y,Lee H,Hu H,Scheben A,Edwards D

更新日期：2018-01-22 00:00:00

abstract：:Leafminer insects of the genus Liriomyza are small flies whose larvae feed on the internal tissue of some of the most important crop plants for the human diet. Several of these pest species are highly uniform from the morphological point of view, meaning molecular data represents the only reliable taxonomic tool usefu...

journal_title：Genes

authors： Carapelli A,Soltani A,Leo C,Vitale M,Amri M,Mediouni-Ben Jemâa J

更新日期：2018-11-15 00:00:00

abstract：:Pyrethroid resistance in major malaria vectors such as Anopheles funestus threatens malaria control efforts in Africa. Cytochrome P450-mediated metabolic resistance is best understood for CYP6P9 genes in southern Africa in An. funestus. However, we do not know if this resistance mechanism is spreading across Africa an...

journal_title：Genes

authors： Djuicy DD,Hearn J,Tchouakui M,Wondji MJ,Irving H,Okumu FO,Wondji CS

更新日期：2020-11-05 00:00:00

abstract：:Cultivation of faba bean (Vicia faba L.) in Tunisia is largely based on improved varieties of the crop. However, a few farmers continue to produce local cultivars or landraces. The National Gene Bank of Tunisia (NGBT) recently launched a collection project for faba bean landraces, with special focus on the regions of ...

journal_title：Genes

authors： Babay E,Khamassi K,Sabetta W,Miazzi MM,Montemurro C,Pignone D,Danzi D,Finetti-Sialer MM,Mangini G

更新日期：2020-02-24 00:00:00

abstract：:Cell size affects almost all biosynthetic processes by controlling the size of organelles and disrupting the nutrient uptake process. Yeast cells must reach a critical size to be able to enter a new cell cycle stage. Abnormal changes in cell size are often observed under pathological conditions such as cancer disease....

journal_title：Genes

authors： Zhao X,Li X,Zhang P,Li C,Feng W,Zhu X,Wei D

更新日期：2020-04-16 00:00:00

abstract：:The efficient extraction of DNA from challenging samples, such as bones, is critical for the success of downstream genotyping analysis in molecular genetic disciplines. Even though the ancient DNA community has developed several protocols targeting small DNA fragments that are typically present in decomposed or old sp...

journal_title：Genes

authors： Xavier C,Eduardoff M,Bertoglio B,Amory C,Berger C,Casas-Vargas A,Pallua J,Parson W

更新日期：2021-01-22 00:00:00

abstract：:GOLDEN2-LIKE (GLK) is a member of the myeloblastosis (MYB) family transcription factor and it plays an important role in the regulation of plastid development and stress tolerance. In this study, a gene named AhGLK1b was identified from a cultivated peanut showing down-regulation in response to low calcium with a comp...

journal_title：Genes

authors： Ali N,Chen H,Zhang C,Khan SA,Gandeka M,Xie D,Zhuang W

更新日期：2020-03-24 00:00:00

abstract：:Eimeria tenella (E. tenella) is one of the most frequent and pathogenic species of protozoan parasites of the genus Eimeria that exclusively occupies the cecum, exerting a high economic impact on the poultry industry. To investigate differentially expressed genes (DEGs) in the cecal tissue of Jinghai yellow chickens i...

journal_title：Genes

authors： Wang X,Zou W,Yu H,Lin Y,Dai G,Zhang T,Zhang G,Xie K,Wang J,Shi H

更新日期：2019-05-31 00:00:00

abstract：:In the years since the first complete human genome sequence was reported, there has been a rapid development of technologies to facilitate high-throughput sequence analysis of DNA (termed "next-generation" sequencing). These novel approaches to DNA sequencing offer the promise of complete genomic analysis at a cost fe...

journal_title：Genes

authors： Anderson MW,Schrijver I

更新日期：2010-05-25 00:00:00

abstract：:Despite recent genetic advances and numerous ongoing therapeutic trials, malignant melanoma remains fatal, and prognostic factors as well as more efficient treatments are needed. The development of such research strongly depends on the availability of appropriate models recapitulating all the features of human melanom...

journal_title：Genes

authors： Prouteau A,André C

更新日期：2019-06-30 00:00:00

abstract：:Coat color dilution corresponds to a specific pigmentation phenotype that leads to a dilution of wild type pigments. It affects both eumelanin and pheomelanin containing melanosomes. The mode of inheritance of the dilution phenotype is autosomal recessive. Candidate gene approaches focused on the melanophilin (MLPH) g...

journal_title：Genes

authors： Demars J,Iannuccelli N,Utzeri VJ,Auvinet G,Riquet J,Fontanesi L,Allain D

更新日期：2018-08-23 00:00:00

abstract：:Gene duplication is an important evolutionary mechanism allowing to provide new genetic material and thus opportunities to acquire new gene functions for an organism, with major implications such as speciation events. Various processes are known to allow a gene to be duplicated and different models explain how duplica...

journal_title：Genes

authors： Lallemand T,Leduc M,Landès C,Rizzon C,Lerat E

更新日期：2020-09-04 00:00:00

abstract：:While the clinical benefit of proteasome inhibitors (PIs) for multiple myeloma (MM) treatment remains unchallenged, dose-limiting toxicities and the inevitable emergence of drug resistance limit their long-term utility. Disease eradication is compromised by drug resistance that is either present de novo or therapy-ind...

journal_title：Genes

authors： Malek E,Kim BG,Driscoll JJ

更新日期：2016-10-06 00:00:00

abstract：:DNA double-strand breaks (DSBs) jeopardize genome integrity and can-when repaired unfaithfully-give rise to structural rearrangements associated with cancer. Exogenous agents such as ionizing radiation or chemotherapy can invoke DSBs, but a vast amount of breakage arises during vital endogenous DNA transactions, such ...

journal_title：Genes

authors： Bouwman BAM,Crosetto N

更新日期：2018-12-14 00:00:00

abstract：:The large phenotypic variation in the olfactory bulb may be related to heterogeneity in the progenitor cells. Accordingly, the progeny of subventricular zone (SVZ) progenitor cells that are destined for the olfactory bulb is of particular interest, specifically as there are many facets of these progenitors and their m...

journal_title：Genes

authors： Sánchez-González R,Figueres-Oñate M,Ojalvo-Sanz AC,López-Mascaraque L

更新日期：2020-03-13 00:00:00

abstract：:Hypertrophic cardiomyopathy associated with damaging variants in the ALPK3 gene is a fairly recent discovery, and only a small number of patients have been described thus far. Here we present two additional patients with hypertrophic cardiomyopathy caused by biallelic variants in ALPK3. Genetic investigation was perfo...

journal_title：Genes

authors： Jorholt J,Formicheva Y,Vershinina T,Kiselev A,Muravyev A,Demchenko E,Fedotov P,Zlotina A,Rygkov A,Vasichkina E,Sejersen T,Kostareva A

更新日期：2020-10-15 00:00:00

abstract：:Satellite DNAs are tandemly repeated sequences preferentially assembled into large arrays within constitutive heterochromatin and their transcription is often activated by stress conditions, particularly by heat stress. Bioinformatic analyses of sequenced genomes however reveal single repeats or short arrays of satell...

journal_title：Genes

authors： Feliciello I,Sermek A,Pezer Ž,Matulić M,Ugarković Đ

更新日期：2020-06-18 00:00:00

abstract：:Terpenoids play important roles in plant defense. Although some terpene synthases have been characterized, terpenoids and their biosynthesis in wheat (Triticumaestivum L.) still remain largely unknown. Here, we describe the identification of a terpene synthase gene in wheat. It encodes a sesquiterpene synthase that ca...

journal_title：Genes

authors： Pu Q,Liang J,Shen Q,Fu J,Pu Z,Liu J,Wang X,Wang Q

更新日期：2019-06-10 00:00:00

abstract：:Rice seed is a pivotal reproductive organ that directly determines yield and quality. Long non-coding RNAs (lncRNAs) have been recognized as key regulators in plant development, but the roles of lncRNAs in rice seed development remain unclear. In this study, we performed a paired-end RNA sequencing in samples of rice ...

journal_title：Genes

authors： Zhao J,Ajadi AA,Wang Y,Tong X,Wang H,Tang L,Li Z,Shu Y,Liu X,Li S,Wang S,Liu W,Zhang J

更新日期：2020-02-26 00:00:00

abstract：:The conserved Notch pathway is reported to be involved in progesterone synthesis and secretion; however, the exact effects remain controversial. To determine the role and potential mechanisms of the Notch signaling pathway in progesterone biosynthesis in porcine granulosa cells (pGCs), we first used a pharmacological ...

journal_title：Genes

authors： Guo R,Chen F,Shi Z

更新日期：2020-01-22 00:00:00

abstract：:It is increasingly recognised that lncRNAs play essential regulatory roles in fundamental biological processes and, consequently, that their dysregulation may contribute to major human diseases, including cancer. Better understanding of lncRNA biology may therefore offer new insights into pathogenetic mechanisms and t...

journal_title：Genes

authors： Pickard MR,Williams GT

更新日期：2015-07-07 00:00:00

abstract：:Elite athlete status is a partially heritable trait, as are many of the underpinning physiological, anthropometrical, and psychological traits that contribute to elite performance. In recent years, our understanding of the specific genetic variants that contribute to these traits has grown, such that there is consider...

journal_title：Genes

authors： Pickering C,Kiely J,Grgic J,Lucia A,Del Coso J

更新日期：2019-11-26 00:00:00

abstract：:Plant genomes generated by Sanger and Next Generation Sequencing (NGS) have provided insight into species diversity and evolution. However, Sanger sequencing is limited in its applications due to high cost, labor intensity, and low throughput, while NGS reads are too short to resolve abundant repeats and polyploidy, l...

journal_title：Genes

authors： Li C,Lin F,An D,Wang W,Huang R

更新日期：2017-12-28 00:00:00

abstract：:The histone-like nucleoid structuring protein (H-NS) has played a key role in shaping the evolution of Shigella spp., and provides the backdrop to the regulatory cascade that controls virulence by silencing many genes found on the large virulence plasmid. H-NS and its paralogue StpA are present in all four Shigella sp...

journal_title：Genes

authors： Picker MA,Wing HJ

更新日期：2016-12-01 00:00:00