Abstract:
:This study aimed to evaluate the characteristics of parathyroid carcinoma and to validate the diagnostic value of Tc-methoxyisobutylisonitrile (MIBI) single photon emission computed tomography/x-ray computed tomography (SPECT/CT) for differentiating between parathyroid carcinoma and hyperparathyroidism. Four consecutive patients with suspected primary hyperparathyroidism were enrolled in this study and underwent Tc-MIBI SPECT/CT, ultrasonography, enhanced CT, and MRI. Serum parathyroid hormone (PTH) and calcium were measured. All primary and recurrent lesions showed high focal uptake on Tc-MIBI image, whereas metastatic lymph nodes gave false negative results. The serum PTH was 165.14 ± 90.26 pmol/L, which declined rapidly after surgery. One patient with a persistently high PTH (147.5 pmol/L) after surgery presented with multiple lymphadenopathy in the neck. Higher expression of chromogranin A (CgA) further confirmed parathyroid carcinoma as a rare endocrine tumor. Parathyroid carcinoma is thus usually diagnosed incidentally based on nonspecific multiorgan symptoms of hypercalcemia and hyperparathyroidism. Tc-MIBI SPECT/CT may help to localize the parathyroid carcinoma, while MRI is valuable for detecting metastasis. Serum PTH and CgA serve as circulating biomarkers in parathyroid carcinoma, and raised levels of PTH and CgA together with locoregional lymphadenopathy may indicate parathyroid carcinoma. Further studies are needed.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Chen Z,Fu J,Shao Q,Zhou B,Wang Fdoi
10.1097/MD.0000000000012578subject
Has Abstractpub_date
2018-10-01 00:00:00pages
e12578issue
40eissn
0025-7974issn
1536-5964pii
00005792-201810050-00034journal_volume
97pub_type
杂志文章相关文献
MEDICINE文献大全abstract::The aim of this study was to investigate the usefulness of titanium mesh cage as an interlaminar spacer combined with nitinol shape memory loop fixation in patients with atlantoaxial instability.From April 2009 to March 2017, among the patients with atlantoaxial instability, a total of 30 patients were treated by niti...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000008022
更新日期:2017-09-01 00:00:00
abstract:AIM:Our objective is to assess the effects of epinephrine for out of hospital cardiac arrest. BACKGROUND:Cardiac arrest was the most serious medical incidents with an estimated incidence in the United States of 95.7 per 100,000 person years. Though epinephrine improved coronary and cerebral perfusion, improving a retu...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000017502
更新日期:2019-11-01 00:00:00
abstract:RATIONALE:Traumatic bilateral facet dislocation in the lumbar (L) spine has rarely been reported. All reported cases were presented with acute facet dislocation. However, we present the first case of delayed bilateral facet dislocation at L4-5. PATIENT CONCERNS:A 34-year-old woman presented with back pain after a head...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000012483
更新日期:2018-09-01 00:00:00
abstract::Identification of meaningful cluster modules of differential genes or representative biomarkers related to the stages of ovarian cancer (OC) is pivotal, which may help to detect mechanisms of OC progression and evaluate OC patients' prognosis.We downloaded gene expression data and the corresponding clinical informatio...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000011895
更新日期:2018-08-01 00:00:00
abstract::Irreversible electroporation (IRE) is a new nonthermal tumor ablation modality that induces apoptosis in the treated tissue without affecting collagen. Its use is particularly indicated for tumors involving major structures, such as encompassed or infiltrated vessels and/or ducts, which need to be preserved and hinder...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000946
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:Talaromyces marneffei (T marneffei), known as a significant pathogen in patients with AIDS in Southeast Asia, is a dimorphic fungus, which can cause deadly systematic infection in immunocompromised hosts. What is more, the dimorphic phase transition has been reported as a conspicuous process linked with viru...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000023409
更新日期:2020-11-25 00:00:00
abstract:RATIONAL:Spontaneous adrenal hematoma in pregnancy is a very rare condition. Herein we present an additional rare case of unilateral spontaneous adrenal hematoma in a pregnant woman, aiming to share this experience and summarize the signal characteristics of simple adrenal hematoma in magnetic resonance imaging (MRI). ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000013329
更新日期:2018-11-01 00:00:00
abstract:BACKGROUND:This study will assess the efficacy and safety of Shenmai injection (SMI) for the treatment of chronic heart failure (CHF). METHODS:The following electronic bibliographic databases will be searched from inception to the March 25, 2020 without language and publication time limitations: MEDLINE, PUBMED, Cochr...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000020663
更新日期:2020-06-26 00:00:00
abstract:PURPOSE:The aim of the soft tissue reconstruction of plantar forefoot should yield weight-bearing function and aesthetic contour, which poses a significant challenge for reconstructive surgeons to provide an appropriate flap according to the "like for like" reconstructive principle. Local flaps and pedicled flaps have ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000020819
更新日期:2020-12-11 00:00:00
abstract:BACKGROUND:The study is inclined to investigate the antagonistic effects of endostatin-vascular endothelial growth inhibitor chimeric recombinant adenovirus (Ad-hENDO-VEGI) on homocysteine (Hcy)-induced vascular endothelial cells (VECs) injury in vitro and in vivo. METHODS:Human VECs cell line ECV304 was selected and ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000005197
更新日期:2016-11-01 00:00:00
abstract::Periodontitis is a systemic and chronic inflammatory disease associated with multiple physical conditions. Distress and depression are other problems affecting the progression of periodontitis. However, the causal relationship between depression and periodontitis has not been adequately investigated. This aim of this ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000002347
更新日期:2015-12-01 00:00:00
abstract::Little is known about the effect of nonsteroidal anti-inflammatory drugs (NSAIDs), thiazolidinediones (TZDs), nifedipine and nondihydropyridine calcium channel blockers (CCBs) usage on the risk of all-cause hospitalization among seniors with heart failure (HF). We assessed the risk of all-cause hospitalization associa...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000006239
更新日期:2017-03-01 00:00:00
abstract::To date, there is no clear agreement regarding which is the best method to detect a connective tissue disease (CTD) during the initial diagnosis of interstitial lung diseases (ILD). The aim of our study was to explore the impact of a systematic diagnostic strategy to detect CTD-associated ILD (CTD-ILD) in clinical pra...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000018589
更新日期:2020-01-01 00:00:00
abstract::[This corrects the article DOI: 10.1097/MD.0000000000004949.]. ...
journal_title:Medicine
pub_type: 已发布勘误
doi:10.1097/MD.0000000000006031
更新日期:2017-01-20 00:00:00
abstract:BACKGROUND:Interest in the anesthetic use of xenon, a noble gas, has waxed and waned for decades, and the clinical effects of xenon are still debated. We performed a meta-analysis to compare the clinical efficacy of xenon with that of propofol. METHODS:Electronic searches were performed through December 2017 using var...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000010758
更新日期:2018-05-01 00:00:00
abstract:RATIONALE:Intraocular manifestation of hematopoietic tumors is rare and often difficult to distinguish from inflammation. We report a patient with acute lymphoblastic leukemia (ALL) who developed intraocular infiltration during the remission period. PATIENT CONCERNS:A 40-year-old man presented with hypopyon in his rig...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000018872
更新日期:2020-01-01 00:00:00
abstract:RATIONALE:Primary biliary cholangitis (PBC) is a liver autoimmune disease. If this disease is associated with other liver injury factors, both misdiagnosis and missed diagnosis will easily occur. Therefore, detailed disease history collection and related laboratory examination should be performed on patients with liver...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000012395
更新日期:2018-09-01 00:00:00
abstract:RATIONALE:Therapeutic or diagnostic thoracentesis is widely used in different clinical settings. Cardiac injury, a rare complication, could lead to fatal consequences. We describe a case of cardiac tamponade complicating thoracentesis that was recognized and rescued in a timely manner. PATIENT CONCERNS:A 42-year-old w...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000019778
更新日期:2020-04-01 00:00:00
abstract:RATIONALE:Pegaspargase has been used in the treatment of acute lymphoblastic leukemia with promising results. However, it has also been associated with several potentially serious complications, including thrombosis. Pegaspargase-induced cerebral venous thrombosis and bone marrow necrosis are very rare. PATIENT CONCER...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000008715
更新日期:2017-11-01 00:00:00
abstract::The originally dismal prognosis associated with anti-GBM Ab-mediated GN and Goodpasture's syndrome may be changing as we recognize a broader spectrum of disease, improve general supportive care, and improve specific treatment. Immunosuppressive therapy, if started early in the course of disease, may prevent or allow r...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/00005792-197909000-00002
更新日期:1979-09-01 00:00:00
abstract:RATIONALE:Absent pulmonary valve syndrome (APVS) is a rare congenital heart disease that is often associated with tetralogy of Fallot (TOF). Here, we report 2 cases of APVS associated with TOF diagnosed via fetal echocardiography and discuss their specific ultrasonographic characteristics. PATIENT CONCERNS:Two pregnan...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007747
更新日期:2017-09-01 00:00:00
abstract:RATIONALE:Malignant mesenchymoma (MM) is defined as a heterogeneous malignant soft tissue tumor that consists of 2 or more distinctly different mesenchymal components in addition to fibrosarcomatous elements. Bladder MM was rarely reported in the literature and there are only 5 cases of primary bladder MM documented in...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007579
更新日期:2017-08-01 00:00:00
abstract::[This corrects the article DOI: 10.1097/MD.0000000000004841.]. ...
journal_title:Medicine
pub_type: 已发布勘误
doi:10.1097/MD.0000000000006217
更新日期:2017-02-17 00:00:00
abstract::To evaluate the effects of different etching concentrations of phosphoric acid on the microtensile bond strength of Adper Single Bond 2 to fluorotic teeth.Deidentified extracted teeth were collected, including 30 sound teeth, 30 teeth with mild fluorosis, 30 teeth with moderate fluorosis, and 30 teeth with severe fluo...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000012093
更新日期:2018-08-01 00:00:00
abstract::Recent studies have revealed a link between estradiol (E2) and glucose homeostasis. We aimed to assess the association between cord blood hormone levels and the risk of gestational diabetes mellitus (GDM).A total of 204 pregnant women with GDM and 204 pregnant women without GDM (control) were included in the study. Ma...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000006962
更新日期:2017-05-01 00:00:00
abstract:RATIONALE:Lupus erythematosus tumidus (LET) is an uncommon type of cutaneous lupus erythematosus (CLE) that is rarely associated with other forms of lupus erythematosus. PATIENT CONCERNS:We report a 62-year-old Chinese man presented with recurrent erythematous facial plaques for 1 year and a low-grade fever for 1 week...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000010375
更新日期:2018-04-01 00:00:00
abstract::To date, a small number of studies concerning the effects and safety of tenofovir disoproxil fumarate (TDF) in Chinese individuals were conducted. In this study, we aimed to assess the antiviral effects and nephrotoxicity of TDF in Chinese patients with chronic hepatitis B virus (HBV) infection.Patients with chronic H...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000017590
更新日期:2019-10-01 00:00:00
abstract::Since the progression of cirrhosis is accelerated each time a complication recurs, the management and treatment of the complication is critical in enhancement of the quality of life and expectation of life in patients. The use of model for end-stage liver disease with incorporation of serum-sodium (MELD-Na) with physi...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000017862
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND:Intubation using direct laryngoscopy is a risky and painful procedure that is associated with undesirable hemodynamic changes such as tachycardia, hypertension, and arrhythmia. Recently, intravenous oxycodone was introduced and used for the control of acute postoperative pain and to attenuate intubation-rela...
journal_title:Medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/MD.0000000000015509
更新日期:2019-05-01 00:00:00
abstract::[This corrects the article DOI: 10.1097/MD.0000000000004251.]. ...
journal_title:Medicine
pub_type: 已发布勘误
doi:10.1097/MD.0000000000005665
更新日期:2016-12-09 00:00:00