Abstract:
:A considerable amount of data supports a 1.8-7.4-fold increased mortality associated with Cushing's syndrome (CS). This is attributed to a high occurrence of several cardiovascular disease (CVD) risk factors in CS [e.g. adiposity, arterial hypertension (AHT), dyslipidaemia and type 2 diabetes mellitus (T2DM)]. Therefore, practically all patients with CS have the metabolic syndrome (MetS), which represents a high CVD risk. Characteristically, despite a relatively young average age, numerous patients with CS display a 'high' or 'very high' CVD risk (i.e. risk of a major CVD event >20% in the following 10 years). Although T2DM is listed as a condition with a high CVD risk, CS is not, despite the fact that a considerable proportion of the CS population will develop T2DM or impaired glucose tolerance. CS is also regarded as a risk factor for aortic dissection in current guidelines. This review considers the evidence supporting listing CS among high CVD risk conditions.
journal_name
Curr Vasc Pharmacoljournal_title
Current vascular pharmacologyauthors
Koracevic G,Stojkovic M,Lovic D,Pavlovic M,Kostic T,Kutlesic M,Micic S,Koracevic M,Djordjevic Mdoi
10.2174/1570161116666181005122339subject
Has Abstractpub_date
2020-01-01 00:00:00pages
12-24issue
1eissn
1570-1611issn
1875-6212pii
CVP-EPUB-93469journal_volume
18pub_type
杂志文章,评审abstract::Adipocytes are no longer considered just as cells related to storage of energy and thermoregulation. Now we know that they release a huge number of paracrine and endocrine biologically active molecules. This is also the case for perivascular adipose tissue (PVAT) that surrounds almost all blood vessels in the organism...
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doi:10.2174/1570161112666140423220628
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doi:10.2174/1570161114666160728093323
更新日期:2016-01-01 00:00:00
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doi:10.2174/1570161115666170830141852
更新日期:2018-01-01 00:00:00
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journal_title:Current vascular pharmacology
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更新日期:2015-01-01 00:00:00
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doi:10.2174/1570161117666190619143005
更新日期:2020-01-01 00:00:00
abstract:: ...
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doi:10.2174/1570161117999190403163922
更新日期:2019-01-01 00:00:00
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journal_title:Current vascular pharmacology
pub_type: 杂志文章,多中心研究
doi:10.2174/1570161115666170529090700
更新日期:2018-01-01 00:00:00
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journal_title:Current vascular pharmacology
pub_type: 杂志文章,评审
doi:10.2174/157016110790886992
更新日期:2010-03-01 00:00:00
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journal_title:Current vascular pharmacology
pub_type: 杂志文章,评审
doi:10.2174/157016107779317251
更新日期:2007-01-01 00:00:00
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journal_title:Current vascular pharmacology
pub_type:
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更新日期:2014-01-01 00:00:00
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journal_title:Current vascular pharmacology
pub_type: 杂志文章,评审
doi:10.2174/1570161052773898
更新日期:2005-01-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.2174/157016111201140327163302
更新日期:2014-01-01 00:00:00
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journal_title:Current vascular pharmacology
pub_type: 杂志文章,评审
doi:10.2174/1570161033386600
更新日期:2003-03-01 00:00:00
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journal_title:Current vascular pharmacology
pub_type: 杂志文章,评审
doi:10.2174/157016112803520927
更新日期:2012-11-01 00:00:00
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journal_title:Current vascular pharmacology
pub_type: 杂志文章,评审
doi:
更新日期:2013-03-01 00:00:00
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journal_title:Current vascular pharmacology
pub_type: 杂志文章,评审
doi:10.2174/1570161043476410
更新日期:2004-04-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.2174/1570161052773870
更新日期:2005-01-01 00:00:00
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pub_type: 社论,评审
doi:10.2174/157016109788340712
更新日期:2009-07-01 00:00:00
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doi:10.2174/1570161113666150916093451
更新日期:2016-01-01 00:00:00
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journal_title:Current vascular pharmacology
pub_type: 杂志文章,评审
doi:10.2174/157016109789043883
更新日期:2009-10-01 00:00:00
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journal_title:Current vascular pharmacology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.2174/157016112803520765
更新日期:2012-11-01 00:00:00
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journal_title:Current vascular pharmacology
pub_type: 杂志文章,评审
doi:10.2174/157016109787354132
更新日期:2009-01-01 00:00:00
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pub_type: 临床试验,杂志文章
doi:10.2174/1567201812666150120163025
更新日期:2015-01-01 00:00:00
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journal_title:Current vascular pharmacology
pub_type: 杂志文章,评审
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更新日期:2012-07-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2013-09-01 00:00:00
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journal_title:Current vascular pharmacology
pub_type: 杂志文章,评审
doi:10.2174/157016111796197233
更新日期:2011-07-01 00:00:00