Abstract:
:Controlling the structure of catalysts at the atomic level provides an opportunity to establish detailed understanding of the catalytic form-to-function and realize new, non-equilibrium catalytic structures. Here, advanced thin-film deposition is used to control the atomic structure of La2/3Sr1/3MnO3, a well-known catalyst for the oxygen reduction reaction. The surface and sub-surface is customized, whereas the overall composition and d-electron configuration of the oxide is kept constant. Although the addition of SrMnO3 benefits the oxygen reduction reaction via electronic structure and conductivity improvements, SrMnO3 can react with ambient air to reduce the surface site availability. Placing SrMnO3 in the sub-surface underneath a LaMnO3 overlayer allows the catalyst to maintain the surface site availability while benefiting from improved electronic effects. The results show the promise of advanced thin-film deposition for realizing atomically precise catalysts, in which the surface and sub-surface structure and stoichiometry are tailored for functionality, over controlling only bulk compositions.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Eom CJ,Kuo DY,Adamo C,Moon EJ,May SJ,Crumlin EJ,Schlom DG,Suntivich Jdoi
10.1038/s41467-018-06503-8subject
Has Abstractpub_date
2018-10-02 00:00:00pages
4034issue
1issn
2041-1723pii
10.1038/s41467-018-06503-8journal_volume
9pub_type
杂志文章abstract::Whilst demonstrated extensively in vitro, the control of cell behaviour via modulation of substrate compliance in live tissues has not been accomplished to date. Here we propose that stem cells can be regulated solely through in situ modulation of tissue biomechanics. By first establishing, via high-resolution Brillou...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-09331-6
更新日期:2019-04-03 00:00:00
abstract::Deregulation of transcription factors (TFs) is an important driver of tumorigenesis, but non-invasive assays for assessing transcription factor activity are lacking. Here we develop and validate a minimally invasive method for assessing TF activity based on cell-free DNA sequencing and nucleosome footprint analysis. W...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-12714-4
更新日期:2019-10-11 00:00:00
abstract::Predictable stereoselective formation of supramolecular assembly is generally believed to be an important but complicated process. Here, we show that point chirality of a ligand decisively influences its supramolecular assembly behavior. We designed three closely related chiral ligands with different point chiralities...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-01025-1
更新日期:2017-10-24 00:00:00
abstract::Charge acceleration during an intense light field application to solids attracts much attention as elementary processes in high-harmonic generation and photoelectron emission. For manipulating such attosecond dynamics of charge, carrier-envelope-phase (CEP: relative phase between carrier oscillation of light field and...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-17776-3
更新日期:2020-08-18 00:00:00
abstract::A cloak that can hide living creatures from sight is a common feature of mythology but still remains unrealized as a practical device. To preserve the wave phase, the previous cloaking solution proposed by Pendry and colleagues required transformation of the electromagnetic space around the hidden object in such a way...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3652
更新日期:2013-01-01 00:00:00
abstract::The nitrogen-vacancy (NV) centre in diamond is a promising candidate for a solid-state qubit. However, its charge state is known to be unstable, discharging from the qubit state NV(-) into the neutral state NV(0) under various circumstances. Here we demonstrate that the charge state can be controlled by an electrolyti...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms1729
更新日期:2012-03-06 00:00:00
abstract::Stimulation of TNFR1 by TNFα can promote three distinct alternative mechanisms of cell death: necroptosis, RIPK1-independent and -dependent apoptosis. How cells decide which way to die is unclear. Here, we report that TNFα-induced phosphorylation of RIPK1 in the intermediate domain by TAK1 plays a key role in regulati...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-00406-w
更新日期:2017-08-25 00:00:00
abstract::Chromosomal rearrangements are essential events in the pathogenesis of both malignant and nonmalignant disorders, yet the factors affecting their formation are incompletely understood. Here we develop a zinc-finger nuclease translocation reporter and screen for factors that modulate rearrangements in human cells. We i...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms15110
更新日期:2017-04-27 00:00:00
abstract::Bcl9 and Pygo are Wnt enhanceosome components that effect β-catenin-dependent transcription. Whether they mediate β-catenin-dependent neoplasia is unclear. Here we assess their roles in intestinal tumourigenesis initiated by Apc loss-of-function (ApcMin), or by Apc1322T encoding a partially-functional Apc truncation c...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-08164-z
更新日期:2019-02-13 00:00:00
abstract::It is unclear why atmospheric oxygen remained trapped at low levels for more than 1.5 billion years following the Paleoproterozoic Great Oxidation Event. Here, we use models for erosion, weathering and biogeochemical cycling to show that this can be explained by the tectonic recycling of previously accumulated sedimen...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms14379
更新日期:2017-02-02 00:00:00
abstract::The original version of this Article contained an error in the spelling of the author Woochul Song, which was incorrectly given as Woochul C. Song. This has been corrected in both the PDF and HTML versions of the Article. ...
journal_title:Nature communications
pub_type: 杂志文章,已发布勘误
doi:10.1038/s41467-018-05447-3
更新日期:2018-08-14 00:00:00
abstract::The emergence of personalized and stratified medicine requires label-free, low-cost diagnostic technology capable of monitoring multiple disease biomarkers in parallel. Silicon photonic biosensors combine high-sensitivity analysis with scalable, low-cost manufacturing, but they tend to measure only a single biomarker ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms12769
更新日期:2016-09-14 00:00:00
abstract::A nest of begging chicks invites an intuitive explanation: needy chicks want to be fed and parents want to feed them. Surprisingly, however, in a quarter of species studied, parents ignore begging chicks. Furthermore, parents in some species even neglect smaller chicks that beg more, and preferentially feed the bigges...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms10985
更新日期:2016-03-29 00:00:00
abstract::ATAC-seq has become a leading technology for probing the chromatin landscape of single and aggregated cells. Distilling functional regions from ATAC-seq presents diverse analysis challenges. Methods commonly used to analyze chromatin accessibility datasets are adapted from algorithms designed to process different expe...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-14497-5
更新日期:2020-02-06 00:00:00
abstract::There is a critical need for standard approaches to assess, report and compare the technical performance of genome-scale differential gene expression experiments. Here we assess technical performance with a proposed standard 'dashboard' of metrics derived from analysis of external spike-in RNA control ratio mixtures. ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms6125
更新日期:2014-09-25 00:00:00
abstract::Graphyne allotropes of carbon are fascinating materials, and their electronic properties are predicted to rival those of the "wonder material" graphene. One allotrope of graphyne, having rectangular symmetry rather than hexagonal, stands out as particularly attractive, namely 6,6,12-graphyne. It is currently an insurm...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-11700-0
更新日期:2019-08-16 00:00:00
abstract::Multiciliated cells (MCCs) harbor dozens to hundreds of motile cilia, which generate hydrodynamic forces important in animal physiology. In vertebrates, MCC differentiation involves massive centriole production by poorly characterized structures called deuterosomes. Here, single-cell RNA sequencing reveals that human ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-06768-z
更新日期:2018-11-07 00:00:00
abstract::Amongst the many spectacular properties of hybrid lead halide perovskites, their defect tolerance is regarded as the key enabler for a spectrum of high-performance optoelectronic devices that propel perovskites to prominence. However, the plateauing efficiency enhancement of perovskite devices calls into question the ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-16463-7
更新日期:2020-06-01 00:00:00
abstract::Long-chain alcohols synthesis (LAS, C5+OH) from syngas provides a promising route for the conversion of coal/biomass/natural gas into high-value chemicals. Cu-Fe binary catalysts, with the merits of cost effectiveness and high CO conversion, have attracted considerable attention. Here we report a nano-construct of a F...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-13691-4
更新日期:2020-01-03 00:00:00
abstract::In vitro fabrication of functional vascularized three-dimensional tissues has been a long-standing objective in the field of tissue engineering. Here we report a technique to engineer cardiac tissues with perfusable blood vessels in vitro. Using resected tissue with a connectable artery and vein as a vascular bed, we ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms2406
更新日期:2013-01-01 00:00:00
abstract::Leaves lose approximately 400 H2O molecules for every 1 CO2 gained during photosynthesis. Most long-distance water transport in plants, or xylem sap flow, serves to replace this water to prevent desiccation. Theory predicts that the largest vessels contribute disproportionately to overall sap flow because flow in pipe...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-13673-6
更新日期:2019-12-10 00:00:00
abstract::For the large-scale sustainable implementation of polymer electrolyte membrane fuel cells in vehicles, high-performance electrocatalysts with low platinum consumption are desirable for use as cathode material during the oxygen reduction reaction in fuel cells. Here we report a carbon black-supported cost-effective, ef...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms15938
更新日期:2017-07-24 00:00:00
abstract::Identification of lymph node (LN) metastasis is essential for staging of solid tumors, and as a result, surgeons focus on harvesting significant numbers of LNs during ablative procedures for pathological evaluation. Isolating those LNs most likely to harbor metastatic disease can allow for a more rigorous evaluation o...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-13076-7
更新日期:2019-11-06 00:00:00
abstract::Protein-protein interactions featuring intricate binding epitopes remain challenging targets for synthetic inhibitors. Interactions of NEMO, a scaffolding protein central to NF-κB signaling, exemplify this challenge. Various regulators are known to interact with different coiled coil regions of NEMO, but the topologic...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-15576-3
更新日期:2020-04-14 00:00:00
abstract::Glucagon promotes hepatic gluconeogenesis and maintains whole-body glucose levels during fasting. The regulatory factors that are involved in fasting glucagon response are not well understood. Here we report a role of p52, a key activator of the noncanonical nuclear factor-kappaB signaling, in hepatic glucagon respons...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-12351-x
更新日期:2019-09-20 00:00:00
abstract::Proton conductive materials are of significant importance and highly desired for clean energy-related applications. Discovery of practical metal-organic frameworks (MOFs) with high proton conduction remains a challenge due to the use of toxic chemicals, inconvenient ligand preparation and complication of production at...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-07414-4
更新日期:2018-11-22 00:00:00
abstract::Many bacteria can exchange genetic material through horizontal gene transfer (HGT) mediated by plasmids and plasmid-borne transposable elements. Here, we study the population structure and dynamics of over 10,000 bacterial plasmids, by quantifying their genetic similarities and reconstructing a network based on their ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-16282-w
更新日期:2020-05-15 00:00:00
abstract::The experimental investigation of quantum devices incorporating mechanical resonators has opened up new frontiers in the study of quantum mechanics at a macroscopic level. It has recently been shown that surface acoustic waves (SAWs) can be piezoelectrically coupled to superconducting qubits, and confined in high-qual...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-01063-9
更新日期:2017-10-17 00:00:00
abstract::The outcome of adult cochlear implantation is predicted positively by the involvement of visual cortex in speech processing, and negatively by the cross-modal recruitment of the right temporal cortex during and after deafness. How these two neurofunctional predictors concur to modulate cochlear implant (CI) performanc...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms14872
更新日期:2017-03-28 00:00:00
abstract::Enantioenriched 1,4-dienes are versatile building blocks in asymmetric synthesis, therefore their efficient synthesis directly from chemical feedstock is highly sought after. Here, we show an enantioselective cross-hydroalkenylation of cyclic 1,3-diene and hetero-substituted terminal olefin by using a chiral [NHC-Ni(a...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-16139-2
更新日期:2020-05-08 00:00:00