Coinfection with cryptococcus and aspergillus in an immunocompetent adult: A case report.


RATIONALE:Aspergillus and Cryptococcus exposure can cause serious secondary infections in human lungs, especially in immunocompromised patients or in conjunction with a chronic disease caused by low disease resistance. Primary invasive fungal infections are clinically rare; therefore, coexistence of 2 fungi at an infection site is uncommon. This paper reports a case of healthy male who was diagnosed with both Cryptococcus neoformans and Aspergillus infections. PATIENT CONCERNS:A healthy 33-year-old male office worker was admitted to the Second Hospital of Jilin University for hemoptysis. A chest computed tomography (CT) scan showed a cavity, which was formed by the thick dorsal wall of the lower left lobe with an irregular inner wall and burr changes around the lesion. INTERVENTION:After 1.0 week of antibiotic and antituberculosis treatment, the hemoptysis symptoms remained. A resection of the left lower lobe was performed. DIAGNOSES:The postoperative pathological reports indicated the presence of both Aspergillus and Cryptococcus. The 2 fungal lesions were separate but within the same location. OUTCOMES:After treatment, the patient no longer had hemoptysis. LESSONS:The current study indicated that fungi can infect not only immunocompromised patients but also healthy people, and that there can be 2 separate fungal infections at the same infection site.


Medicine (Baltimore)




Wang Q,Wang Z,Hao Y,Li W,Xin T,Chen M,Gao P




Has Abstract


2018-09-01 00:00:00
















  • Usefulness of titanium mesh cage for posterior C1-C2 fixation in patients with atlantoaxial instability.

    abstract::The aim of this study was to investigate the usefulness of titanium mesh cage as an interlaminar spacer combined with nitinol shape memory loop fixation in patients with atlantoaxial instability.From April 2009 to March 2017, among the patients with atlantoaxial instability, a total of 30 patients were treated by niti...


    pub_type: 杂志文章


    authors: Yang HS,Kim KW,Oh YM,Eun JP

    更新日期:2017-09-01 00:00:00

  • Effect of high-flow nasal cannula oxygen therapy vs conventional oxygen therapy on adult postcardiothoracic operation: A meta-analysis.

    abstract:INTRODUCTION:The effect of high-flow nasal cannula (HFNC) on adult post cardiothoracic operation remains controversial. We conducted a meta-analysis of randomized controlled trials to evaluate the effect of HFNC and conventional oxygen therapy (COT) on postcardiothoracic surgery. METHODS:A search was conducted in Emba...


    pub_type: 杂志文章,meta分析


    authors: Wu X,Cao W,Zhang B,Wang S

    更新日期:2018-10-01 00:00:00

  • The ratio of estimated average glucose to fasting plasma glucose level as an indicator of insulin resistance in young adult diabetes: An observational study.

    abstract::At present, glycated hemoglobin (HbA1c) and glycated albumin (GA) are used to evaluate glycemic control in diabetic patients, but they cannot reflect insulin deficiency and/or insulin resistance.We investigated the feasibility of using estimated average glucose to fasting plasma glucose ratio (eAG/fPG ratio) to estima...


    pub_type: 杂志文章


    authors: Guo J,Lei S,Zhou Y,Pan C

    更新日期:2020-10-02 00:00:00

  • Gatekeeping and the utilization of community health services in Shenzhen, China: A cross-sectional study.

    abstract::To assess the effects of the gatekeeper policy implemented in Shenzhen, China, in conjunction with a labor health insurance program, on channeling patients toward community health centers (CHCs).Eight thousand patients who visited 8 CHCs in Shenzhen were surveyed between May 1, 2013 and July 28, 2013. Half of the pati...


    pub_type: 杂志文章


    authors: Li W,Gan Y,Dong X,Zhou Y,Cao S,Kkandawire N,Cong Y,Sun H,Lu Z

    更新日期:2017-09-01 00:00:00

  • Late-Onset Immune Thrombocytopenic Purpura After Withdrawal of Interferon Treatment for Chronic Hepatitis C Infection: A Case Report.

    abstract::Immune thrombocytopenic purpura (ITP) is a life-threatening complication following pegylated interferon alpha (PEG-IFN) plus ribavirin treatment, the standard treatment for hepatitis C virus (HCV) infection. We reported a rare case with late-onset ITP after withdrawal of PEG-IFN treatment.A 53-year-old male with hepat...


    pub_type: 杂志文章


    authors: Hsiao CH,Tseng KC,Tseng CW,Tung CH

    更新日期:2015-08-01 00:00:00

  • Risk factors of invasive candidiasis in critical cancer patients after various gastrointestinal surgeries: A 4-year retrospective study.

    abstract::For early diagnosis and treatment of invasive candidiasis (IC), the well-known risk factors may not apply in the intensive care unit (ICU). This retrospective study identified the risk factors predicting IC and candidemia in cancer patients under intensive care after gastrointestinal surgery.Enrolled were 229 cancer p...


    pub_type: 杂志文章


    authors: Xia R,Wang D

    更新日期:2019-11-01 00:00:00

  • Bioinformatics analysis to identify the critical genes, microRNAs and long noncoding RNAs in melanoma.

    abstract::Melanoma, which is usually induced by ultraviolet light exposure and the following DNA damage, is the most dangerous skin cancer. The purpose of the present study was to screen key molecules involved in melanoma.Microarray data of E-MTAB-1862 were downloaded from the ArrayExpress database, which included 21 primary me...


    pub_type: 杂志文章


    authors: Zhang Q,Wang Y,Liang J,Tian Y,Zhang Y,Tao K

    更新日期:2017-07-01 00:00:00

  • Transient Global Amnesia After Cerebral Angiography With Iomeprol: A Case Report.

    abstract::Transient global amnesia is now considered a very rare complication of cerebral angiography. Various etiological mechanisms have been suggested to account for this complication, but no consensus has been reached yet. This case report documents one of the few reported cases of cerebral angiography-related transient glo...


    pub_type: 杂志文章


    authors: Tiu C,Terecoasă EO,Grecu N,Dorobăţ B,Marinescu AN,Băjenaru OA

    更新日期:2016-05-01 00:00:00

  • Pathological fracture of the mandible caused by radicular cyst: A case report and literature review.

    abstract:RATIONALE:Pathological fracture of the mandible caused by radicular cyst is rare. This report describes a unique case of a mandibular pathological fracture caused by radicular cyst, arising from an endodontically treated molar. PATIENT CONCERN:A 49-year-old female was referred to our department with persistent pain in...


    pub_type: 杂志文章,评审


    authors: Xiao X,Dai JW,Li Z,Zhang W

    更新日期:2018-12-01 00:00:00

  • Noncancer-Related Health Events and Mortality in Head and Neck Cancer Patients After Definitive Radiotherapy: A Prospective Study.

    abstract::The survival of patients with head and neck squamous cell carcinoma (HNSCC) can be affected not only by progression of the original cancer or occurrence of a second cancer but also by noncancer health event (NCHE). In this study, we evaluated the prognostic significance of early NCHEs in HNSCC patients after definitiv...


    pub_type: 杂志文章


    authors: Kang HS,Roh JL,Kim SB,Choi SH,Nam SY,Kim SY

    更新日期:2016-05-01 00:00:00

  • Optimal intervention time and risk of the activating blood and removing stasis method in acute cerebral hemorrhage patients: A randomized placebo-controlled trial.

    abstract:INTRODUCTION:Stroke is the leading cause of disability-adjusted life years in neurological diseases and has become one of the top 3 fatal diseases in the world. Cerebral hemorrhage accounts for approximately 18% to 24% of all strokes in Asian countries. Cerebral hemorrhage is one of the most destructive subtypes of str...


    pub_type: 杂志文章,多中心研究


    authors: Ma Y,Zhang D,Lv Z,Cui Y,Fei Y,Chang T,Yu M,Lu J,Huang Q,Zhang Y,Xu P,Lan T,Wang J

    更新日期:2021-01-15 00:00:00

  • Rare ocular manifestations in an 11-year-old girl with incomplete Kawasaki disease: A case report.

    abstract:INTRODUCTION:Kawasaki disease is a necrotizing vasculitis featuring fever, erythema, conjunctivitis, and lymphadenopathy. Ocular manifestations in Kawasaki disease are commonly limited to anterior segment, posterior segment lesions are rarely reported. CASE PRESENTATION:We report a unique case of ocular manifestations...


    pub_type: 杂志文章


    authors: Gao Y,Zhang Y,Lu F,Wang X,Zhang M

    更新日期:2018-06-01 00:00:00

  • Effects of remifentanil versus nitrous oxide on postoperative nausea, vomiting, and pain in patients receiving thyroidectomy: Propensity score matching analysis.

    abstract::Remifentanil and nitrous oxide (N2O) are 2 commonly used anesthetic agents. Both these agents are known risk factors for postoperative nausea and vomiting (PONV). However, remifentanil and N2O have not been directly compared in a published study. Remifentanil can induce acute tolerance or hyperalgesia, thus affecting ...


    pub_type: 杂志文章


    authors: Kim MK,Yi MS,Kang H,Choi GJ

    更新日期:2016-10-01 00:00:00

  • Sex estimation from sternal measurements using multidetector computed tomography.

    abstract::We aimed to show the utility and reliability of sternal morphometric analysis for sex estimation.Sex estimation is a very important step in forensic identification. Skeletal surveys are main methods for sex estimation studies. Morphometric analysis of sternum may provide high accuracy rated data in sex discrimination....


    pub_type: 杂志文章


    authors: Ekizoglu O,Hocaoglu E,Inci E,Bilgili MG,Solmaz D,Erdil I,Can IO

    更新日期:2014-12-01 00:00:00

  • Comparison of psychiatric disturbances in patients with multiple sclerosis and neuromyelitis optica.

    abstract::Although both multiple sclerosis (MS) and neuromyelitis optica (NMO) are demyelinating diseases, their psychiatric disturbances may differ given differences in the neurological manifestations. We used subjective and objective measurements to compare the psychiatric disturbances in patients with MS and NMO.Psychiatric ...


    pub_type: 杂志文章


    authors: Shin JS,Kwon YN,Choi Y,Lee JY,Lee YI,Hwang JH,Choi SH,Kim SM

    更新日期:2019-09-01 00:00:00

  • Acupuncture for asthma: Protocol for a systematic review.

    abstract:BACKGROUND:Asthma is a common chronic disease in both adults and children. Inhaled corticosteroids (ICS) and β2-agonists are the major medications treating asthma with many side effects. Acupuncture has been used in many diseases including asthma. We aim to assess the efficacy and safety of acupuncture for asthma. MET...


    pub_type: 杂志文章


    authors: Li M,Zhang X,Bao H,Li C,Zhang P

    更新日期:2017-06-01 00:00:00

  • Case report of intestinal non-rotation, heterotaxy, and polysplenia in a patient with pancreatic cancer.

    abstract:RATIONALE:Heterotaxy with polysplenia is an extremely rare congenital condition resulting from abnormal arrangement of organs in the abdominal and thoracic cavities during embryologic development. When a malignancy such as pancreatic cancer develops under these conditions, surgical resection becomes particularly comple...


    pub_type: 杂志文章


    authors: Pagkratis S,Kryeziu S,Lin M,Hoque S,Bucobo JC,Buscaglia JM,Georgakis GV,Sasson AR,Kim J

    更新日期:2017-12-01 00:00:00

  • Interleukin-8 gene polymorphism -251T>A contributes to Alzheimer's disease susceptibility.

    abstract:BACKGROUND:Published association studies have investigated the correlation between interleukin-8 (IL-8) gene polymorphism -251T>A and susceptibility to Alzheimer's disease (AD); however, the results are conflicting. Thus, we conducted the meta-analysis to reassess the effect of IL-8 gene -251T>A variant on the risk of ...


    pub_type: 杂志文章,meta分析,评审


    authors: Qin B,Li L,Wang S,Wu J,Huang Y,Zhou P,Bai J,Zheng Y

    更新日期:2016-09-01 00:00:00

  • Case report: A non-obstructive azoospermia patient with heat shock factor-2 mutation.

    abstract:RATIONALE:Infertility is a common medical condition that affects nearly 15% of the world population. Non-obstructive azoospermia (NOA) is one of the most severe forms of male infertility. Some common structural variants, single nucleotide polymorphisms (SNPs), and genetic factors were reported to be associated with NOA...


    pub_type: 杂志文章


    authors: Zhao H,Zhang H,Xi Q,Li L,Zhu H,Hu X,Liu R

    更新日期:2020-07-31 00:00:00

  • A novel approach for medical research on lymphomas: A study validation of claims-based algorithms to identify incident cases.

    abstract::The use of claims database to study lymphomas in real-life conditions is a crucial issue in the future. In this way, it is essential to develop validated algorithms for the identification of lymphomas in these databases. The aim of this study was to assess the validity of diagnosis codes in the French health insurance...


    pub_type: 杂志文章


    authors: Conte C,Palmaro A,Grosclaude P,Daubisse-Marliac L,Despas F,Lapeyre-Mestre M

    更新日期:2018-01-01 00:00:00

  • Hand metastasis in a patient with cervical cancer: A case report.

    abstract:INTRODUCTION:Acrometastasis is infrequent and generally indicates a wider spread of metastasis with poor prognosis. The diagnosis is challenging, as it might mimic an infectious, inflammatory, or metabolic disease. Acrometastasis are most commonly found in patients with lung, gastrointestinal, kidney, and breast cancer...


    pub_type: 杂志文章


    authors: Gallardo-Alvarado L,Ramos AA,Perez-Montiel D,Ramirez-Morales R,Diaz E,Leon DC

    更新日期:2020-07-02 00:00:00

  • Sex Differences in the Morphine-Sparing Effects of Intraoperative Dexmedetomidine in Patient-Controlled Analgesia Following General Anesthesia: A Consort-Prospective, Randomized, Controlled Clinical Trial.

    abstract::Previous studies have reported that intraoperative dexmedetomidine has morphine-sparing effects in patient-controlled analgesia (PCA). The present study was designed to investigate the possible sex differences in the morphine-sparing effects of intraoperative dexmedetomidine following general anesthesia. A total of 22...


    pub_type: 杂志文章,随机对照试验


    authors: Li YY,Ge DJ,Li JY,Qi B

    更新日期:2016-05-01 00:00:00

  • Risk factors and long-term outcome for postoperative intra-abdominal infection after hepatectomy for hepatocellular carcinoma.

    abstract::Intra-abdominal infection (IAI) after hepatectomy is an important morbidity. Identification of risk factors that could be avoided in the perioperative period may reduce the prevalence of IAI after hepatectomy for hepatocelluar carcinoma (HCC).Between January 1995 and December 2009, all patients with HCC who underwent ...


    pub_type: 杂志文章


    authors: Tang H,Lu W,Yang Z,Jiang K,Chen Y,Lu S,Dong J

    更新日期:2017-04-01 00:00:00

  • Associations of human leukocyte antigen and interleukin-18 gene polymorphisms with viral load in patients with hepatitis B infection.

    abstract::This study aimed to assess the associations of human leukocyte antigen (HLA)-DR and interleukin (IL)-18 gene polymorphisms with hepatitis B virus (HBV).Clinical data were retrospectively reviewed between December 2006 and December 2015 at Xiangyang Central Hospital. HBV patients were assigned to the high and low viral...


    pub_type: 杂志文章


    authors: Jiang H,Cao F,Cao H,Rao Q,Yang Y

    更新日期:2018-07-01 00:00:00

  • Periocular triamcinolone acetonide injection for treating polypoidal choroidal vasculopathy concurrent with hemorrhagic retinal detachment.

    abstract::To investigate the clinical efficiency of periocular triamcinolone acetonide (TA) injection for treating polypoidal choroidal vasculopathy (PCV) concurrent with hemorrhagic retinal detachment (HRD).Twenty-two cases confirmed with PCV concurrent with HRD characterized by massive subretinal hemorrhage and exudation pres...


    pub_type: 杂志文章


    authors: Zhang K,Chen Y,Sun X,Zhong Q,Lin L,Gao Y,Hong F

    更新日期:2018-09-01 00:00:00

  • Biomarkers of gastric cancer-related ischemic stroke and its underlying pathogenesis.

    abstract::This study aimed to investigate the biomarkers and underlying pathogenesis of ischemic stroke in patients with gastric cancer (GC).Patients with active gastric cancer who had experienced acute ischemic stroke without conventional vascular risk factors (gastric cancer-related stroke [GCS] group) and visited The First A...


    pub_type: 杂志文章


    authors: Long H,Qin K,Chen J,Chen Y,Chen L,Zeng J,Liang Z

    更新日期:2018-04-01 00:00:00

  • Reporting and methodological quality of survival analysis in articles published in Chinese oncology journals.

    abstract::Survival analysis methods have gained widespread use in the filed of oncology. For achievement of reliable results, the methodological process and report quality is crucial. This review provides the first examination of methodological characteristics and reporting quality of survival analysis in articles published in ...


    pub_type: 杂志文章


    authors: Zhu X,Zhou X,Zhang Y,Sun X,Liu H,Zhang Y

    更新日期:2017-12-01 00:00:00

  • Erratum: Association of Lifestyle-Related Comorbidities With Periodontitis: A Nationwide Cohort Study in Korea: Erratum.

    abstract::[This corrects the article DOI: 10.1097/MD.0000000000001567.]. ...


    pub_type: 已发布勘误



    更新日期:2016-01-15 00:00:00

  • Validation of the mortality in emergency department sepsis (MEDS) score in a Singaporean cohort.

    abstract::The emergency department (ED) serves as the first point of hospital contact for most septic patients. Early mortality risk stratification using a quick and accurate triage tool would have great value in guiding management. The mortality in emergency department sepsis (MEDS) score was developed to risk stratify patient...


    pub_type: 杂志文章


    authors: Pong JZ,Koh ZX,Samsudin MI,Fook-Chong S,Liu N,Ong MEH

    更新日期:2019-08-01 00:00:00

  • MiR-664a-3p expression in patients with obstructive sleep apnea: A potential marker of atherosclerosis.

    abstract::The early prediction of atherosclerosis (AS) is important in the management of obstructive sleep apnea patients (OSA). MicroRNA (miRNA) plays a vital role in the evolution of OSA and AS. Its differential expression may therefore serve as a diagnostic and prognostic biomarker of AS in OSA. The aim of this study was to ...


    pub_type: 杂志文章


    authors: Li K,Chen Z,Qin Y,Wei Y

    更新日期:2018-02-01 00:00:00