Smooth Muscle Alpha Actin Immunoexpression (α-Sma) and CD-117 Antibody (C-Kit) in Capsules Formed by Polyurethane Foam-Coated Silicone Implants and with Textured Surface: A Study on Rats.


BACKGROUND:One of the undesirable complications that might occur after breast augmentation with silicone implants is capsular contracture. In its etiology, the relations between mast cells and myofibroblasts play an important role in collagen synthesis. Mast cells are able to activate fibroblasts into myofibroblasts, through paracrine secretions, inducing collagen production. The objectives of this study were to analyze the myofibroblast concentration through the α-SMA immunomarker and evaluate the intensity of mast cell expression against the C-Kit immunomarker. MATERIAL AND METHOD:Sixty-four Wistar rats were used, divided into two groups (polyurethane foam and textured surface) with 32 animals in each. The animals received silicone implants on the back, below the panniculus carnosus, and after the determined period, they were killed and the capsules formed around the implants were studied. The capsules were analyzed employing the immunohistochemical technique, with the α-SMA and C-Kit immunomarkers in subgroups of 30, 50, 70 and 90 days. RESULTS:The myofibroblast concentration was higher in the polyurethane group when compared to the textured group (30 days p = 0.105; 50 days p = 0.247; 70 days p = 0.014 and 90 days p = 0.536). The intensity of mast cell expression was more pronounced in the polyurethane group when compared to the textured group (30 days p = 0.798; 50 days p = 0.537; 70 days p = 0.094 and 90 days p = 0.536). CONCLUSIONS:Polyurethane-coated implants induced higher concentrations of myofibroblasts and higher expression of mast cells, when compared to the textured surface implants. NO LEVEL ASSIGNED:This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors .


Aesthetic Plast Surg


Silva EN,Ribas-Filho JM,Tabushi FI,Silva MAP,Siqueira EBD,de Noronha L,da Silva ABD,Lipinski LC,Guth I,Vosgerau LM




Has Abstract


2019-02-01 00:00:00














  • New options in breast reconstructive surgery: alternatives to the latissimus dorsi musculocutaneous flap.

    abstract::Transposition of the latissimus dorsi musculocutaneous flap is still considered by most authors a first-choice technique for breast reconstruction. However, the aesthetic drawbacks of the technique are significant: In our experience the posterior scar and the "patchlike" skin island are of concern to more than 30% of ...

    journal_title:Aesthetic plastic surgery

    pub_type: 杂志文章


    authors: Berrino P,Galli A,Santi PL

    更新日期:1986-01-01 00:00:00

  • Correction of capsular contracture by insertion of a breast prosthesis anterior to the original capsule and preservation of the contracted capsule: technique and outcomes.

    abstract:BACKGROUND:This study aimed to explore the treatment of capsular contracture after augmentation mammaplasty by insertion of a breast prosthesis anterior to the original capsule. METHODS:Through transaxillary or submammary incisions and small capsular incisions, 14 patients (18 breasts) with Baker grades 3 and 4 capsul...

    journal_title:Aesthetic plastic surgery

    pub_type: 杂志文章


    authors: Xue H,Lee SY

    更新日期:2011-12-01 00:00:00

  • Y-scar vertical mammaplasty for treatment of mild macromastia with pseudoptosis.

    abstract::Y-scar vertical mammaplasty is a technical modification of vertical scar breast reduction, which avoids superior areolar scarring. It has been previously shown to be particularly useful in young patients with mild macromastia and minimal or no ptosis. This case report presents a new indication for which to apply this ...

    journal_title:Aesthetic plastic surgery

    pub_type: 杂志文章


    authors: Akyurek M

    更新日期:2010-08-01 00:00:00

  • Body image dissatisfaction in male cosmetic surgery patients.

    abstract::This study was the first empirical investigation of body image dissatisfaction in male cosmetic surgery patients. Thirty men completed two body image measures prior to their initial consultation. Results were compared to the norms for each of the measures and with a sample of 30 women seeking similar cosmetic procedur...

    journal_title:Aesthetic plastic surgery

    pub_type: 杂志文章


    authors: Pertschuk MJ,Sarwer DB,Wadden TA,Whitaker LA

    更新日期:1998-01-01 00:00:00

  • Avoiding Psychological Pitfalls in Aesthetic Medical Procedures.

    abstract:OBJECTIVE:To assess the prevalence of body dysmorphic disorder (BDD) in an aesthetic surgery setting in the region of Southwest China, and to ascertain the differences in terms of body images between patients in the aesthetic setting and general Chinese population. This study tracked patient satisfaction with their bod...

    journal_title:Aesthetic plastic surgery

    pub_type: 杂志文章


    authors: Wang Q,Cao C,Guo R,Li X,Lu L,Wang W,Li S

    更新日期:2016-12-01 00:00:00

  • Prevention of acute hematoma after face-lifts.

    abstract::Acute hematoma remains one of the most frequently encountered complications after face-lift surgery. Several risk factors inherent to the patient and omission of certain intraoperative regimens are considered to cause hematoma. Significant risk factors include high blood pressure and male gender. Possible intraoperati...

    journal_title:Aesthetic plastic surgery

    pub_type: 杂志文章


    authors: Beer GM,Goldscheider E,Weber A,Lehmann K

    更新日期:2010-08-01 00:00:00

  • Effect of Platelet-Rich Fibrin on Fat Grafting in Animal Models: A Meta-Analysis.

    abstract:BACKGROUND:Autologous fat grafting has been widely used in plastic and reconstructive surgery, but one of the main reasons for limiting its application is the high resorption rate. Platelet-rich fibrin (PRF) is a new generation of platelet concentrate that has recently been used to improve the survival rate of fat graf...

    journal_title:Aesthetic plastic surgery

    pub_type: 杂志文章,meta分析


    authors: Liu R,Long Y,Liu L,Zhao X

    更新日期:2020-04-01 00:00:00

  • Secondary nasal revisions after rhinoplasties.

    abstract::This article describes procedures for correcting some of the most common deformities after rhinoplasty. Double or triple osteotomies, partial removal of the nasal bones, autogenous cartilage transplantations, and the value of the transplantation of auricular composite grafts are discussed. ...

    journal_title:Aesthetic plastic surgery

    pub_type: 杂志文章


    authors: Walter CD

    更新日期:1978-12-01 00:00:00

  • Histological characterization of human breast implant capsules.

    abstract:BACKGROUND:This study investigated the relationships between histomorphological aspects of breast capsules, including capsule thickness, collagen fiber alignment, the presence of α-smooth muscle actin (α-SMA)-positive myofibroblasts, and clinical observations of capsular contracture. METHODS:Breast capsule samples wer...

    journal_title:Aesthetic plastic surgery

    pub_type: 杂志文章


    authors: Bui JM,Perry T,Ren CD,Nofrey B,Teitelbaum S,Van Epps DE

    更新日期:2015-06-01 00:00:00

  • Subdermal liposuction.

    abstract::Liposuction is a widely used technique today and indications are that it is becoming even more popular due to new technical refinements. The use of cannulae with a smaller diameter allows suction of the fat immediately under the dermis. The cannula we use to perform this new kind of fat suction is straight and has an ...

    journal_title:Aesthetic plastic surgery

    pub_type: 杂志文章


    authors: Gasperoni C,Salgarello M,Emiliozzi P,Gargani G

    更新日期:1990-04-01 00:00:00

  • Ultrasonic Liposculpturing.

    abstract::The author describes a revolutionary body contouring technique based on the surgical use of ultrasonic energy. It allows the selective destruction of only excess adipose tissue. The technique is based on three fundamental steps: (1) preparation of the areas to be treated with a large infiltration of a special solution...

    journal_title:Aesthetic plastic surgery

    pub_type: 杂志文章


    authors: Zocchi M

    更新日期:2020-08-01 00:00:00

  • Patient-Reported Outcomes of Three Different Types of Breast Reconstruction with Correlation to the Clinical Data 5 Years Postoperatively.

    abstract:BACKGROUND:The aim of this study was to compare long-term clinical and patient-reported outcomes in terms of satisfaction and health-related quality of life (HRQoL) following postmastectomy breast reconstruction using BREAST-Q in patients undergoing implant-based reconstruction, abdominal-based autologous reconstructio...

    journal_title:Aesthetic plastic surgery

    pub_type: 杂志文章


    authors: Ticha P,Mestak O,Wu M,Bujda M,Sukop A

    更新日期:2020-12-01 00:00:00

  • Revision Abdominoplasty with Truncal Liposculpting: A 10-Year Experience.

    abstract:INTRODUCTION:Abdominoplasty is one of the most popular body-contouring procedures. Despite its popularity, classic abdominoplasty is still associated with a significant rate of complaints from patients such as: fullness of flanks and epigastric areas, lack of a posterior lumbar curve, hanging skin over the incision lin...

    journal_title:Aesthetic plastic surgery

    pub_type: 杂志文章


    authors: Sterodimas A,Boriani F,Nicaretta B,Pereira LH

    更新日期:2019-02-01 00:00:00

  • Toxic shock syndrome associated with suction-assisted lipectomy.

    abstract::Toxic shock syndrome (TSS) is a serious, potentially life-threatening condition resulting from an exotoxin of Staphylococcus aureus. Presenting symptoms include high fever, diarrhea, nausea, and vomiting progressing to hypotension, oliguria, conjunctival hyperemia, and an erythematous rash over the trunk, abdomen, and...

    journal_title:Aesthetic plastic surgery

    pub_type: 杂志文章,评审


    authors: Rhee CA,Smith RJ,Jackson IT

    更新日期:1994-04-01 00:00:00

  • Augmentation mammoplasty/mastopexy: lessons learned from 107 aesthetic cases.

    abstract:BACKGROUND:One-stage augmentation/mastopexy entails the challenge of augmenting breast volume with an implant while resecting excess skin. Although both augmenting and lifting the breast in a one-stage operation is gaining in popularity, its safety and its efficacy are still under debate and merit deeper evaluation. M...

    journal_title:Aesthetic plastic surgery

    pub_type: 杂志文章


    authors: Castello MF,Silvestri A,Nicoli F,Dashti T,Han S,Grassetti L,Torresetti M,Perdanasari AT,Zhang YX,Di Benedetto G,Lazzeri D

    更新日期:2014-10-01 00:00:00

  • The Use of a Retromammary Adipofascial Flap in Breast Augmentation for Patients with Thin Soft Tissue.

    abstract:BACKGROUND:In patients with a thin soft tissue breast envelope, lower pole implant palpability is a postoperative sequela that concerns patients. Anatomically, the lower aspect of the breast near the inframammary fold lacks sufficient soft tissue to cover the breast implant after augmentation. METHODS:A transareolar i...

    journal_title:Aesthetic plastic surgery

    pub_type: 杂志文章


    authors: Han HH,Kim KK,Lee KH,Kim IB,Lee PK

    更新日期:2018-12-01 00:00:00

  • An improved method of removing polyurethane foam-covered gel prostheses.

    abstract::One of the advantages of polyurethane foam-covered prostheses has been that in the first 5 to 10 years after their use, the amount of capsular contraction was found much less than when similar "slick" prostheses were used. Another advance was their fixation to the surrounding tissue thus giving a more natural appearan...

    journal_title:Aesthetic plastic surgery

    pub_type: 杂志文章


    authors: Cohney BC,Mitchell S

    更新日期:1997-05-01 00:00:00

  • A comparison of diced cartilage grafts wrapped in perichondrium versus fascia.

    abstract:UNLABELLED:Cartilage grafts are the most commonly used grafts for structural and aesthetic purposes. This study aimed to compare the viability of diced cartilage grafts wrapped in fascia with diced cartilage grafts wrapped in perichondrium. Approximately 2 × 2 cm cartilage grafts were harvested from the ears of seven N...

    journal_title:Aesthetic plastic surgery

    pub_type: 杂志文章


    authors: Kemaloğlu CA,Tekin Y

    更新日期:2014-12-01 00:00:00

  • Skin-muscle flap lower lid blepharoplasty: an easier dissection.

    abstract::Most descriptions of the skin-muscle flap lower lid blepharoplasty, the so-called McIndoe technique, indicate dissection of the flap in a cephalad-to-caudad direction from near the ciliary margin toward the bony orbital rim. However, this report describes a technical variation in which counter-traction and lateral-to-...

    journal_title:Aesthetic plastic surgery

    pub_type: 杂志文章


    authors: Aston SJ

    更新日期:1982-01-01 00:00:00

  • Ectropion after blepharoplasty prevention and treatment.

    abstract::Ectropion is the most common serious complication following blepharoplasty for the correction of baggy eyelid deformity. Although blepharoplasty may be considered one of the most gratifying plastic operations, if an ectropion results it then becomes one of the most distressing to patient and surgeon alike.Ectropion co...

    journal_title:Aesthetic plastic surgery

    pub_type: 杂志文章


    authors: Castañares S

    更新日期:1978-12-01 00:00:00

  • Improved patient satisfaction with augmentation mammoplasty: the transaxillary subpectoral approach.

    abstract::A survey from 1983 through 1988 of patients who underwent augmentation mammoplasty performed by the transaxillary subpectorial approach revealed the operation to be amazingly trouble-free, with patient satisfaction reaching 98.5%. The severe problem of capsular contracture seen in the 1978 prepectoral (submammary) cas...

    journal_title:Aesthetic plastic surgery

    pub_type: 杂志文章


    authors: Hetter GP

    更新日期:1991-04-01 00:00:00

  • The forehead lift : Some hints to secure better results.

    abstract::The operation for the forehead lift is reviewed considering the experience acquired in recent years in order to facilitate its safe execution. Particular attention is given to the removal of factors limiting the free upward movement of the frontal flap, such as preparation of the meso temporalis. The treatment of the ...

    journal_title:Aesthetic plastic surgery

    pub_type: 杂志文章


    authors: Marino H

    更新日期:1976-12-01 00:00:00

  • A triangular suture to simplify reduction mammaplasty.

    abstract::A technique to facilitate correct preoperative marking for an en bloc resection in superiorly based mammaplasty is presented. A temporary triangular suture is placed to control the estimated resection lines for the removal of the medial and lateral tissue block. The described technique helps to avoid the formation of ...

    journal_title:Aesthetic plastic surgery

    pub_type: 杂志文章


    authors: Wechselberger G,Schoeller T,Papp C

    更新日期:1998-11-01 00:00:00

  • The treatment of prominent ears: a 25-year survey of the island technique.

    abstract::The authors report on a 25-year retrospective study of 488 cases of prominent (protruding) ears corrected by the island technique of Pitanguy. ...

    journal_title:Aesthetic plastic surgery

    pub_type: 杂志文章


    authors: Pitanguy I,Müller P,Piccolo N,Ramalho E,Solinas R

    更新日期:1987-01-01 00:00:00

  • Direct approach to the difficult anterior neck region.

    abstract::This article presents an alternative method to correct the sagging neck with a local dermolipectomy and median platysma duplication. The technique is recommended mainly for the older patient with redundant skin and fat in that region and who, for some reason, does not want to undergo a facelift. ...

    journal_title:Aesthetic plastic surgery

    pub_type: 杂志文章


    authors: Kesselring UK

    更新日期:1992-10-01 00:00:00

  • Conservative mastectomies.

    abstract::Nowadays, oncological breast surgery has to be performed to maximize cosmetic results, and even mastectomies, when unavoidable, should conform to acceptable aesthetics. We investigated surgical approaches to skin-sparing mastectomies. Scar positioning and volume replacement were evaluated. We also discuss nipple-spari...

    journal_title:Aesthetic plastic surgery

    pub_type: 杂志文章,评审


    authors: Nava MB,Catanuto G,Pennati A,Garganese G,Spano A

    更新日期:2009-09-01 00:00:00

  • The effect of epidermal growth factor on autogenous fat graft.

    abstract::Autogenous fat grafting is widely used for the correction of soft tissue contour deformity. However, the high absorption rate results in the need for overcorrection, and graft longevity is unpredictable. The authors hypothesized that epidermal growth factor (EGF), a potent stimulator of neovascularization, would impro...

    journal_title:Aesthetic plastic surgery

    pub_type: 杂志文章


    authors: Park B,Kong JS,Kang S,Kim YW

    更新日期:2011-10-01 00:00:00

  • Evaluation of aesthetic abdominal surgery using a new clinical scale.

    abstract:BACKGROUND:Evaluation of outcomes after aesthetic surgery still is a challenge in plastic surgery. The evaluation frequently is based on subjective criteria. This study used a new clinical grading scale to evaluate aesthetic results for plastic surgeries to the abdomen. The method scores each of the following five para...

    journal_title:Aesthetic plastic surgery

    pub_type: 杂志文章


    authors: Salles AG,Ferreira MC,do Nascimento Remigio AF,Gemperli R

    更新日期:2012-02-01 00:00:00

  • Autologous Dermal Mesh in Severe Postpregnancy Recti Muscles Diastasis.

    abstract:INTRODUCTION:The severe postpregnancy diastasis of recti muscles causes a biomechanical alteration of the statics of the trunk and an unaesthetic bulging of the abdominal wall. This is always combined with cutaneous and subcutaneous excess, which is different on a case-by-case basis. There is not a consensus on the bes...

    journal_title:Aesthetic plastic surgery

    pub_type: 杂志文章


    authors: Bucaria V,Boccuzzi A

    更新日期:2020-10-27 00:00:00

  • Increasing projection in patients undergoing free nipple graft reduction mammoplasty.

    abstract::Reduction mammoplasty in patients with gigantomastia has traditionally been performed by a technique involving free nipple grafting. These patients usually have only a small amount of breast tissue above the inframammary fold and therefore this type of procedure has often left patients with an insufficient amount of s...

    journal_title:Aesthetic plastic surgery

    pub_type: 杂志文章


    authors: Abramson DL

    更新日期:1999-07-01 00:00:00