Familial hypercholesterolemia in Canada: Initial results from the FH Canada national registry.

Abstract:

BACKGROUND AND AIMS:Familial hypercholesterolemia (FH) is under-diagnosed and under-treated in most of the world, including Canada. National registries play a key role in identifying patients with FH, understanding gaps in care, and advancing the science of FH to better treat these patients. METHODS:FH Canada has established a national registry across 19 academic sites acting as "hubs" in Canada to increase awareness and access to standard-of-care therapies. RESULTS:To-date, more than 3000 patients with FH have been entered into a secure, web-based database. Early outcomes of this initiative include a greater understanding of treatment gaps for patients with FH in Canada, the development of a new, simplified Canadian definition of FH, and tools to aid in the diagnosis of FH, including imputation of baseline levels of LDL cholesterol. CONCLUSIONS:As the national registry expands in size and scope, further learning will emerge with ultimate benefit for the diagnosis and treatment of FH in Canada.

journal_name

Atherosclerosis

journal_title

Atherosclerosis

authors

Brunham LR,Ruel I,Khoury E,Hegele RA,Couture P,Bergeron J,Baass A,Dufour R,Francis GA,Cermakova L,Mancini GBJ,Brophy JM,Brisson D,Gaudet D,Genest J

doi

10.1016/j.atherosclerosis.2018.05.040

subject

Has Abstract

pub_date

2018-10-01 00:00:00

pages

419-424

eissn

0021-9150

issn

1879-1484

pii

S0021-9150(18)30283-1

journal_volume

277

pub_type

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