Familial hypercholesterolemia in Canada: Initial results from the FH Canada national registry.

abstract：:Evidence is emerging that the contribution of atherosclerosis to the development of abdominal aortic aneurysm may differ from that of other manifestations of arterial disease. B-mode ultrasound may be helpful in understanding the characteristics and factors that contribute to the development of different manifestation...

journal_title：Atherosclerosis

authors： Simons PC,Algra A,Bots ML,Banga JD,Grobbee DE,van der Graaf Y

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Galectin-3 binding protein (Gal-3BP) is a secreted protein associated with inflammation and carotid atherosclerosis. We hypothesized that high Gal-3BP levels may indicate unfavorable plaque morphology and outcome in coronary artery disease (CAD). METHODS:Gal-3BP plasma levels were measured by ELISA...

journal_title：Atherosclerosis

authors： Gleissner CA,Erbel C,Linden F,Domschke G,Akhavanpoor M,Doesch AO,Buss SJ,Giannitsis E,Katus HA,Korosoglou G

更新日期：2016-08-01 00:00:00

abstract：AIMS:Besides carotid or cardiac embolism, stroke can occur via microangiopathy (small arterial disease [SAD]) and macroangiopathy (intracranial atherosclerotic stroke [ICAS]) of the intracranial vasculature. There have been efforts to identify risk factors specific to microangiopathy and macroangiopathy, including vasc...

journal_title：Atherosclerosis

authors： Bang OY,Chung JW,Ryoo S,Moon GJ,Kim GM,Chung CS,Lee KH

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:Prospective studies have supported the beneficial effects of n-3 fatty acid consumption on cardiac deaths, but limited data focused on atherosclerosis. We investigated the associations between n-3 fatty acids in erythrocytes and atherosclerosis in middle-aged and older Chinese. METHODS:847 subjects (285 men ...

journal_title：Atherosclerosis

authors： Dai XW,Zhang B,Wang P,Chen CG,Chen YM,Su YX

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND AND AIMS:We recently showed that miR-223-3p on high-density lipoproteins (HDL) is exported to endothelial cells, where it inhibits inflammation. However, the origin of miR-223-3p on HDL is unknown. We hypothesize that HDL-associated miR-223-3p originates in myeloid cells and is exported to HDL in a scavenger...

journal_title：Atherosclerosis

authors： Cuesta Torres LF,Zhu W,Öhrling G,Larsson R,Patel M,Wiese CB,Rye KA,Vickers KC,Tabet F

更新日期：2019-07-01 00:00:00

abstract：:Remnant-like particles (RLPs) are closely associated with coronary heart disease and can induce endothelial dysfunction through oxidative mechanisms. Many risk factors accelerate the onset of endothelial progenitor cells (EPCs) senescence via increased oxidative stress. In this study, we investigated the effect of RLP...

journal_title：Atherosclerosis

authors： Liu L,Wen T,Zheng XY,Yang DG,Zhao SP,Xu DY,Lü GH

更新日期：2009-02-01 00:00:00

abstract：PURPOSE:An elevated systolic blood pressure (SBP) response to a graded maximal exercise stress test (GEST) may be a predictor of endothelial dysfunction and hypertension. We examined relationships among the GEST peak SBP response and indicators of endothelial function. METHODS:Men (n=48, 43.7±1.4 yr) with high BP (145...

journal_title：Atherosclerosis

authors： Olson KM,Augeri AL,Seip RL,Tsongalis GJ,Thompson PD,Pescatello LS

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVES:Compare carotid plaque morphology of acute symptomatic, recently symptomatic and asymptomatic patients (groups 1, 2 and 3 respectively) with carotid artery disease using high resolution magnetic resonance imaging (MRI), to identify high-risk plaque characteristics best associated with risk of recurrent throm...

journal_title：Atherosclerosis

authors： Sadat U,Weerakkody RA,Bowden DJ,Young VE,Graves MJ,Li ZY,Tang TY,Gaunt ME,Hayes PD,Gillard JH

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:The cluster of differentiation-1d (CD1d) recognizes and presents the lipid antigens to NK-T lymphocytes. Atherosclerotic lesions contain atherogenic lipids, mainly cholesterol and its oxides. Peroxisome proliferator-activated receptor-γ (PPARγ) is also known to exist in atherosclerotic lesions, participating ...

journal_title：Atherosclerosis

authors： Rosales C,Tang D,Geng YJ

更新日期：2015-03-01 00:00:00

abstract：:The effect of a fish lipid concentrate rich in eicosapentaenoic acid was studied in 107 subjects for periods up to 2 years. Ninety-two had heart disease or hyper-lipidaemia and 15 had no history of heart disease. Serum triglyceride levels were rapidly reduced, cholesterol fell more slowly but high density lipoprotein ...

journal_title：Atherosclerosis

authors： Saynor R,Verel D,Gillott T

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Although familial hypercholesterolemia (FH) can be effectively managed using cholesterol-lowering medication, patients often fall short of complete treatment adherence. Identifying the psychological factors associated with self-regulation of FH medication is important to inform interventions to maxi...

journal_title：Atherosclerosis

authors： Hagger MS,Hardcastle SJ,Hu M,Kwok S,Lin J,Nawawi HM,Pang J,Santos RD,Soran H,Su TC,Tomlinson B,Watts GF

更新日期：2018-10-01 00:00:00

abstract：AIMS:Apolipoprotein C-III (apoC-III) has been recognized as a useful marker of triglyceride-rich lipoproteins (TRLs) metabolism and proposed as an indicator of prognosis for coronary risk in healthy subjects. We studied cross-sectionally in a population having low cholesterol levels, but a high prevalence of the metabo...

journal_title：Atherosclerosis

authors： Onat A,Hergenç G,Sansoy V,Fobker M,Ceyhan K,Toprak S,Assmann G

更新日期：2003-05-01 00:00:00

abstract：:Apolipoprotein E (apoE) exerts prominent anti-inflammatory effects and undergoes recycling by target cells. We previously reported that the peptide Ac-hE18A-NH(2), composed of the receptor binding domain (LRKLRKRLLR) of apoE covalently linked to the Class A amphipathic peptide 18A, dramatically lowers plasma cholester...

journal_title：Atherosclerosis

authors： Datta G,White CR,Dashti N,Chaddha M,Palgunachari MN,Gupta H,Handattu SP,Garber DW,Anantharamaiah GM

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:Fenofibrate has shown to reduce major cardiovascular events and slow angiographic progression of coronary atherosclerosis. The postulated mechanism of action is via the activation of peroxisomal proliferator-activated receptor-alpha (PPAR-alpha), a nuclear transcription factor that controls a variety of ce...

journal_title：Atherosclerosis

authors： Corti R,Osende J,Hutter R,Viles-Gonzalez JF,Zafar U,Valdivieso C,Mizsei G,Fallon JT,Fuster V,Badimon JJ

更新日期：2007-01-01 00:00:00

abstract：:The role of prostaglandin I2 (PGI2) in the control of DNA synthesis during the cell cycle was investigated in cultured rabbit aortic smooth muscle cells (SMC). SMC at confluency in the G0 state reached the S phase about 16 h after stimulation with serum, as judged by measurement of [3H]thymidine incorporation into DNA...

journal_title：Atherosclerosis

authors： Morisaki N,Kanzaki T,Motoyama N,Saito Y,Yoshida S

更新日期：1988-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Oxidation of low-density lipoprotein (LDL) and oxidized LDL-mediated activation of the innate immune system have been recognized as early key events during the pathogenesis of atherosclerosis. Recent evidence identified eosinophils as a major source of enzymatic lipid oxidation and suggested a poten...

journal_title：Atherosclerosis

authors： Hofheinz K,Seibert F,Ackermann JA,Dietel B,Tauchi M,Oszvar-Kozma M,Kühn H,Schett G,Binder CJ,Krönke G

更新日期：2020-10-01 00:00:00

abstract：UNLABELLED:Recent studies have shown, that chronic flavonoids treatment improves vascular function and cardiovascular remodeling by decreasing superoxide anion production as well as by increasing NO realize from endothelial cells. A progressive decrease in systolic blood pressure and reduction of low-density lipoprotei...

journal_title：Atherosclerosis

authors： Naruszewicz M,Laniewska I,Millo B,Dłuzniewski M

更新日期：2007-10-01 00:00:00

abstract：:Occlusive arterial disease stimulates compensatory growth of pre-existent and new arterial channels which help to maintain organ perfusion. Previous studies characterizing compensatory or collateral vascular growth have been performed in normocholesterolemic animals. Because hyperlipidemic states alter vascular regula...

journal_title：Atherosclerosis

authors： Bucay M,Nguy J,Barrios R,Chen CH,Henry PD

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND AND AIMS:The aim of this study was to investigate the impact of attenuated-signal plaque (ASP) observed by intravascular ultrasound (IVUS) on vessel response after drug-eluting stent implantation. METHODS:Data were derived from the IVUS cohort of the J-DESsERT trial comparing paclitaxel- and sirolimus-eluti...

journal_title：Atherosclerosis

authors： Kitahara H,Waseda K,Sakamoto K,Yamada R,Huang CC,Nakatani D,Sakata K,Kawarada O,Yock PG,Matsuyama Y,Yokoi H,Nakamura M,Muramatsu T,Nanto S,Fitzgerald PJ,Honda Y

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND AND AIMS:The sex- and age-related differences in the composition of iliofemoral atherosclerotic plaques are largely unknown. Therefore, the aim of the current study is to gain insight into plaque composition across strata of age and sex in a large cohort of vascular surgery patients. METHODS:Peripheral athe...

journal_title：Atherosclerosis

authors： de Bakker M,Timmerman N,van Koeverden ID,de Kleijn DPV,de Borst GJ,Pasterkamp G,Boersma E,den Ruijter HM

更新日期：2020-10-01 00:00:00

abstract：:The dose-response effects of clofibrate and niceritrol on serum cholesterol and triglycerides (TG) were studied in 29 patients with Type IIa and IIb hyperlipoproteinaemia. In 17 patients, clofibrate and niceritrol were then given as combined treatment, and the effects of this combination on serum lipoproteins were stu...

journal_title：Atherosclerosis

authors： Olsson AG,Orö L,Rössner S

更新日期：1975-07-01 00:00:00

abstract：:The involvement of endothelium-derived hyperpolarizing factor (EDHF) in the protective effect of 17beta-estradiol was investigated on the phenylephrine-precontracted carotid artery from cholesterol fed rabbits. Animals were fed for 8 weeks as follows: control group, standard chow; (control+estradiol) group, standard c...

journal_title：Atherosclerosis

authors： Ghanam K,Ea-Kim L,Javellaud J,Oudart N

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Autosomal dominant hypercholesterolemia (ADH) is caused by mutations in the low density lipoprotein receptor (LDLR), its ligand apoB (APOB) or proprotein convertase subtilisin/kexin type 9 (PCSK9) genes. Yet DNA sequencing does not identify mutations in these genes in a significant number of cases, suggestin...

journal_title：Atherosclerosis

authors： Awan Z,Choi HY,Stitziel N,Ruel I,Bamimore MA,Husa R,Gagnon MH,Wang RH,Peloso GM,Hegele RA,Seidah NG,Kathiresan S,Genest J

更新日期：2013-12-01 00:00:00

abstract：:The composition of very low density lipoproteins (VLDL: d less than 1.019) of New Zealand male rabbits reciving cholesterol (2 g/day) and metformin (135 mg/kg/day) is investigated. These rabbits, while showing only a slight reduction of plasma cholesterol levels, as compared to cholesterol-fed (h.c.) animals, show a m...

journal_title：Atherosclerosis

authors： Sirtori CR,Catapano A,Ghiselli GC,Innocenti AL,Rodriguez J

更新日期：1977-01-01 00:00:00

abstract：:Familial dysbetalipoproteinemia is characterized by hyperlipidemia, increases in beta-migrating, very low density lipoproteins (beta-VLDL), and homozygosity for apolipoprotein E2 (apo E2). In this study, 3 patients with familial dysbetalipoproteinemia were treated with lovastatin, and kinetics for apolipoprotein B (ap...

journal_title：Atherosclerosis

authors： Vega GL,East C,Grundy SM

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND AND PURPOSES:Pulse wave analysis (PWV), a marker of aortic stiffness, has independent predictive value for cardiovascular morbidity and mortality in both healthy and high-risk populations, especially fatal stroke, and for long-term functional stroke prognosis. Whether arterial stiffness and wave reflection a...

journal_title：Atherosclerosis

authors： Gąsecki D,Rojek A,Kwarciany M,Kowalczyk K,Boutouyrie P,Nyka W,Laurent S,Narkiewicz K

更新日期：2012-12-01 00:00:00

abstract：:The purpose of the present study was to examine the relationship between the changes in the expressions of several mRNAs and changes in endothelial function in streptozotocin-induced diabetic and chronic short-term insulin-treated rats. Aortas from later-stage (10 week) diabetics, but not those from their insulin-trea...

journal_title：Atherosclerosis

authors： Kobayashi T,Oishi K,Hayashi Y,Matsumoto T,Kamata K

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVE:Subjects with metabolic syndrome (MetS) and individuals with type 2 diabetes are at high risk for vascular complications. Hormones acting on vascular endothelium may be involved in the atherogenic process associated with metabolic disorders. The objective of this study was to determine the correlation of pro-...

journal_title：Atherosclerosis

authors： Then C,Kowall B,Lechner A,Meisinger C,Heier M,Koenig W,Peters A,Thiery J,Rathmann W,Seissler J

更新日期：2013-10-01 00:00:00

abstract：:Cholesteryl esters (CE) exchange between lipoproteins through the action of cholesteryl ester transfer protein (CETP). Situations at high risk for atherosclerosis are often accompanied by an accelerated net mass CE transfer (CET) from high density lipoproteins (HDL) to very low (VLDL) and low density lipoproteins (LDL...

journal_title：Atherosclerosis

authors： Elchebly M,Porokhov B,Pulcini T,Berthezène F,Ponsin G

更新日期：1996-06-01 00:00:00

abstract：:The newest guidelines for treating people with coronary artery disease (CAD) suggest benefit from statin-induced LDL cholesterol lowering regardless of baseline LDL cholesterol level. These guidelines were based on recent clinical trials that showed statistically significant statin-induced relative risk reductions (RR...

journal_title：Atherosclerosis

authors： Rembold CM

更新日期：2007-11-01 00:00:00