Abstract:
BACKGROUND AND AIMS:Familial hypercholesterolemia (FH) is under-diagnosed and under-treated in most of the world, including Canada. National registries play a key role in identifying patients with FH, understanding gaps in care, and advancing the science of FH to better treat these patients. METHODS:FH Canada has established a national registry across 19 academic sites acting as "hubs" in Canada to increase awareness and access to standard-of-care therapies. RESULTS:To-date, more than 3000 patients with FH have been entered into a secure, web-based database. Early outcomes of this initiative include a greater understanding of treatment gaps for patients with FH in Canada, the development of a new, simplified Canadian definition of FH, and tools to aid in the diagnosis of FH, including imputation of baseline levels of LDL cholesterol. CONCLUSIONS:As the national registry expands in size and scope, further learning will emerge with ultimate benefit for the diagnosis and treatment of FH in Canada.
journal_name
Atherosclerosisjournal_title
Atherosclerosisauthors
Brunham LR,Ruel I,Khoury E,Hegele RA,Couture P,Bergeron J,Baass A,Dufour R,Francis GA,Cermakova L,Mancini GBJ,Brophy JM,Brisson D,Gaudet D,Genest Jdoi
10.1016/j.atherosclerosis.2018.05.040subject
Has Abstractpub_date
2018-10-01 00:00:00pages
419-424eissn
0021-9150issn
1879-1484pii
S0021-9150(18)30283-1journal_volume
277pub_type
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