Abstract:
BACKGROUND:Focal liver lesions are common in children and adults after Fontan procedures. OBJECTIVE:To explore the relationship between liver shear stiffness, using magnetic resonance (MR) elastography, and the presence of focal liver lesions in patients after Fontan procedures (total cavopulmonary anastomosis). MATERIALS AND METHODS:The retrospective study was approved by the institutional review board and the requirement for informed consent was waived. By searching institutional electronic medical records, we identified all patients with a history of Fontan palliation of congenital heart disease who had undergone same-day liver MR elastography and liver MRI without and with intravenous contrast material between January 2012 and December 2017. Using imaging reports, patients were placed into two groups: 1) no focal liver lesions and 2) one or more focal liver lesions. Patient age, sex, mean liver shear stiffness (kPa) and maximum single anatomical level liver shear stiffness (kPa) were recorded. The Mann-Whitney U test was used to compare age and liver stiffness between groups, while the Fisher exact test was used to assess the impact of gender on liver lesions. RESULTS:Forty-eight patients met study inclusion criteria; 33 (69%) had one or more focal liver lesions. The median age was 20.0 years (IQR [interquartile range]: 10.8-29.1 years) for patients without liver lesions and 19.9 years (IQR: 17.2-27.0 years) for patients with liver lesions (P=0.49). Eleven of 21 male patients (52.4%) had liver lesions compared to 22 of 27 female patients (81.5%) (P=0.058). Mean (4.62 kPa [IQR: 4.10-5.59 kPa] vs. 4.10 kPa [IQR: 3.44-4.80 kPa]; P=0.02) and maximum (5.53 kPa [IQR: 4.64-6.56 kPa] vs. 4.50 kPa [IQR: 3.82-5.35 kPa]; P=0.009) liver stiffness were significantly higher in patients without liver lesions as compared to patients with liver lesions. CONCLUSION:Our study demonstrated a significant negative association between focal liver lesions and increased liver stiffness in patients following Fontan procedures.
journal_name
Pediatr Radioljournal_title
Pediatric radiologyauthors
Diaz ES,Dillman JR,Veldtman GR,Trout ATdoi
10.1007/s00247-018-4264-zsubject
Has Abstractpub_date
2019-01-01 00:00:00pages
99-104issue
1eissn
0301-0449issn
1432-1998pii
10.1007/s00247-018-4264-zjournal_volume
49pub_type
杂志文章abstract::A 6-week-old girl presented with bronchiolitis secondary to respiratory syncytial virus. Eight days after admission she developed a Staphylococcus aureus infection at a previous intravenous cannula site. Despite antibiotic therapy this led to an anterior mediastinal staphylococcal abscess, which was drained surgically...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:
更新日期:1995-11-01 00:00:00
abstract::Lap belt restraints in motor vehicle collisions have been associated with a variety of injuries, mainly bowel and lumbar spine. Cephalad positioning of the belt over the intended position across the anterior superior iliac spines (which typically occurs in younger children) is thought to be responsible for the observe...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-002-0779-3
更新日期:2002-12-01 00:00:00
abstract:BACKGROUND:Infantile Blount disease is a developmental condition characterized by disorganized endochondral ossification in the medial aspect of the proximal tibial physis. OBJECTIVE:To describe the MR imaging abnormalities in the proximal tibia, distal femur, menisci and ligaments of children with infantile Blount di...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-013-2686-1
更新日期:2013-10-01 00:00:00
abstract::The objective of this study was to compare the quality of conventional and helical computed tomography (CT) images in children unable to breath-hold. Sixteen patients (age range 1.1-7.5 years) underwent both conventional and helical chest CT on a General Electric HiSpeed Advantage scanner at a mean study interval of 3...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02021699
更新日期:1995-01-01 00:00:00
abstract::This is the first clinical and angiographic description of congenital subclavian steal in a patient with left aortic arch, isolation of the right subclavian artery, and an aortic diverticulum. ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF01092954
更新日期:1980-07-01 00:00:00
abstract::Certain misleading appearances are peculiar to pediatric uroradiology. The most frequently encountered pitfalls are related to the bladder, to vesicoureteral reflux, and to the duplicated collecting system. The bi-chambered nature of the child's bladder, and the rapid settling of contrast material to the most dependen...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF01644339
更新日期:1980-09-01 00:00:00
abstract::One of the obstacles in discussing childhood tuberculosis (TB) is the lack of standard descriptive terminology to classify the diverse spectrum of disease. Accurate disease classification is important, because the correct identification of the specific disease entity has definite prognostic significance. Accurate clas...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-004-1238-0
更新日期:2004-11-01 00:00:00
abstract::A case of gastro-oesophageal intussusception was reported in 1840 by Von Rokitanski: this is rare, with only two other cases having been reported. In our patient the gastro-oesophageal intussusception followed Nissen fundoplication. ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02019667
更新日期:1990-01-01 00:00:00
abstract::The need for X-ray investigations of the urinary tract at the time of the first proven urinary infection, even in older girls, is stressed. This policy is the best way to detect chronic pyelonephritis and congenital anomalies of the urinary tract and provide timely and appropriate treatment. These conclusions are supp...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF00972109
更新日期:1977-10-28 00:00:00
abstract:OBJECTIVE:Unenhanced MRI has emerged as a useful tool for diagnosing pediatric acute appendicitis. The use of contrast-enhanced MRI for diagnosing pediatric appendicitis has not been documented. The purpose of this study is to examine the diagnostic performance of contrast-enhanced MRI for acute appendicitis and altern...
journal_title:Pediatric radiology
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doi:10.1007/s00247-014-2952-x
更新日期:2014-08-01 00:00:00
abstract::A 3-year-old Algerian boy with unusual facies, mesomelic dysplasia of the upper extremities, meta-epiphyseal changes in the lower extremities and skin dimples is reported. The authors are not able to classify the child's syndrome nosologically. ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02012398
更新日期:1993-01-01 00:00:00
abstract::We report a rare case of cystic metastases to the liver from a peripheral primitive neuroectodermal tumour in a child. Ultrasound and CT appearances are described with a discussion on the histological findings and the differential diagnosis. ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470000347
更新日期:2000-12-01 00:00:00
abstract:BACKGROUND:The expected MRI-based dimensions of the intracranial optic nerve and optic tract in neonates are unknown. OBJECTIVE:To evaluate the sizes of the intracranial optic nerve and optic tract in neonates at term-equivalent age using MRI. MATERIALS AND METHODS:We retrospectively analyzed brain MRI examinations i...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-015-3495-5
更新日期:2016-04-01 00:00:00
abstract::Deep venous thrombosis (DVT) is being increasingly recognized as a significant issue in children. Despite the low incidence of DVT, the risks of pulmonary embolism and death in children are significant. Post-thrombotic syndrome, a syndrome of chronic venous insufficiency, can have long-term adverse consequences in chi...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-013-2634-0
更新日期:2013-08-01 00:00:00
abstract::Purpose. To determine the incidence of neurologic complications of cerebral angiography in children with moyamoya syndrome (MMS) as compared to children without MMS. Materials and methods. One-hundred-ninety consecutive cerebral angiograms obtained in 152 children were evaluated. Sixty of these angiograms were obtaine...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470050474
更新日期:1998-11-01 00:00:00
abstract:BACKGROUND:Traditionally, every patient with an acute scrotum needed surgical exploration for definitive exclusion of testicular torsion. OBJECTIVE:In this study, we aimed to evaluate the improved accuracy in clinical diagnosis with colour Doppler Ultrasonography (US) added to normal clinical assessment. MATERIALS AN...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-005-1411-0
更新日期:2005-06-01 00:00:00
abstract::Fifteen newborn infants developed roentgenographic evidence of rickets while on long-term intravenous hyperalimentation. In each instance, the initial diagnosis of rickets was suggested on the chest roentgenogram, where characteristic cupped and frayed upper humeral metaphyses were noted; subsequent knee and wrist roe...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02386710
更新日期:1978-12-04 00:00:00
abstract::This retrospective study documents the incidence and distribution of fractures in 117 children with end-stage liver disease who underwent orthotopic liver transplantation (OLT) over a 6-year period (1987-1993). Both the pre- and post-OLT phases were included. Nineteen children (16.2 %) sustained a total of 69 fracture...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:
更新日期:1995-11-01 00:00:00
abstract::We used the fast field-echo technique of magnetic resonance (MR) imaging with an intravenous bolus injection of paramagnetic contrast agent to evaluate glomerular function. The time-dependent curves of changes in signal intensity observed in the renal cortex and renal medulla brought about by the paramagnetic contrast...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF01395707
更新日期:1996-01-01 00:00:00
abstract::The clinical, pathologic and roentgenographic features of a case of congenital oxalosis are discussed and contrasted to the more common forms of primary oxalosis. The ease of demonstration of the cortical deposition of calcium oxalate crystals on the CT scanner is reported. ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF01001753
更新日期:1980-11-01 00:00:00
abstract:BACKGROUND:A new children's hospital provided the impetus to investigate radiation dose and image quality in a fluoroscope that was specially engineered for pediatric fluoroscopy. Radiation protection management recommends radiation exposures that are as low as reasonably achievable, while still maintaining diagnostic ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470050728
更新日期:2000-04-01 00:00:00
abstract:BACKGROUND:Foreign body aspiration is common in children, especially those under 3 years of age. Chest radiography and CT are the main imaging modalities for the evaluation of these children. Management of children with suspected foreign body aspiration (SFBA) mainly depends on radiological findings. OBJECTIVE:To inve...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-006-0331-y
更新日期:2007-01-01 00:00:00
abstract::One case of hemorrhage in the cavum septi pellucidi (CSP) is presented. This unusual location of intracranial hemorrhage was demonstrated by cranial sonography in a premature neonate. ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02386822
更新日期:1986-01-01 00:00:00
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journal_title:Pediatric radiology
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更新日期:2004-04-01 00:00:00
abstract::Abdominal aortic injury after blunt trauma is rare in the pediatric population. There have been fewer than 20 reported cases in the literature since 1960, and most were the result of motor vehicle collisions. We report the case of a 16-month-old boy who is the youngest reported patient to sustain this type of injury. ...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/s00247-009-1224-7
更新日期:2009-07-01 00:00:00
abstract::Vertical expandable prosthetic titanium rib (VEPTR) is increasingly used in the treatment of thoracic insufficiency, idiopathic and neuromuscular scoliosis and chest wall defects in children. In contrast to spinal fusion surgery, the VEPTR allows for growth while stabilizing the deformity. We illustrate the common ind...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/s00247-014-3128-4
更新日期:2015-04-01 00:00:00
abstract::The case of a young boy with primary hyperparathyroidism due to an adenoma is reported. The tumor was localized by ultrasonography, and a close correlation between the image and the surgical findings was found. Since primary hyperparathyroidism in children under 15 years of age is frequently due to adenomata larger th...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02386732
更新日期:1984-01-01 00:00:00
abstract::Extracranial hematoma without significant head trauma is uncommon. We discuss a 9-year-old girl who presented with sudden head swelling, bilateral proptosis, extraocular muscle palsy, and progressive visual disturbance after hair braiding. The diagnosis of a large subgaleal hematoma with extension into the superior as...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-009-1176-y
更新日期:2009-06-01 00:00:00
abstract:BACKGROUND:Because of its absence of ionising radiation and possibility for obtaining functional information, MRI is promising for assessing lung disease in children who require repetitive imaging for long-term follow-up. OBJECTIVE:To describe MRI findings in children with cystic fibrosis and evaluate semi-quantitativ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-017-4021-8
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:Fetal MRI can be performed in the second and third trimesters. During this time, the fetal brain undergoes profound structural changes. Interpretation of appropriate development might require comparison with normal age-based models. Consultation of a hard-copy atlas is limited by the inability to compare mul...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-009-1411-6
更新日期:2010-02-01 00:00:00