MRI measured liver stiffness does not predict focal liver lesions after the Fontan operation.

Abstract:

BACKGROUND:Focal liver lesions are common in children and adults after Fontan procedures. OBJECTIVE:To explore the relationship between liver shear stiffness, using magnetic resonance (MR) elastography, and the presence of focal liver lesions in patients after Fontan procedures (total cavopulmonary anastomosis). MATERIALS AND METHODS:The retrospective study was approved by the institutional review board and the requirement for informed consent was waived. By searching institutional electronic medical records, we identified all patients with a history of Fontan palliation of congenital heart disease who had undergone same-day liver MR elastography and liver MRI without and with intravenous contrast material between January 2012 and December 2017. Using imaging reports, patients were placed into two groups: 1) no focal liver lesions and 2) one or more focal liver lesions. Patient age, sex, mean liver shear stiffness (kPa) and maximum single anatomical level liver shear stiffness (kPa) were recorded. The Mann-Whitney U test was used to compare age and liver stiffness between groups, while the Fisher exact test was used to assess the impact of gender on liver lesions. RESULTS:Forty-eight patients met study inclusion criteria; 33 (69%) had one or more focal liver lesions. The median age was 20.0 years (IQR [interquartile range]: 10.8-29.1 years) for patients without liver lesions and 19.9 years (IQR: 17.2-27.0 years) for patients with liver lesions (P=0.49). Eleven of 21 male patients (52.4%) had liver lesions compared to 22 of 27 female patients (81.5%) (P=0.058). Mean (4.62 kPa [IQR: 4.10-5.59 kPa] vs. 4.10 kPa [IQR: 3.44-4.80 kPa]; P=0.02) and maximum (5.53 kPa [IQR: 4.64-6.56 kPa] vs. 4.50 kPa [IQR: 3.82-5.35 kPa]; P=0.009) liver stiffness were significantly higher in patients without liver lesions as compared to patients with liver lesions. CONCLUSION:Our study demonstrated a significant negative association between focal liver lesions and increased liver stiffness in patients following Fontan procedures.

journal_name

Pediatr Radiol

journal_title

Pediatric radiology

authors

Diaz ES,Dillman JR,Veldtman GR,Trout AT

doi

10.1007/s00247-018-4264-z

subject

Has Abstract

pub_date

2019-01-01 00:00:00

pages

99-104

issue

1

eissn

0301-0449

issn

1432-1998

pii

10.1007/s00247-018-4264-z

journal_volume

49

pub_type

杂志文章
  • CT of staphylococcal anterior mediastinal abscess in an infant.

    abstract::A 6-week-old girl presented with bronchiolitis secondary to respiratory syncytial virus. Eight days after admission she developed a Staphylococcus aureus infection at a previous intravenous cannula site. Despite antibiotic therapy this led to an anterior mediastinal staphylococcal abscess, which was drained surgically...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:

    authors: Bungay HK,Shefler AG,McHugh K

    更新日期:1995-11-01 00:00:00

  • Lap belt iliac wing fracture: a predictor of bowel injury in children.

    abstract::Lap belt restraints in motor vehicle collisions have been associated with a variety of injuries, mainly bowel and lumbar spine. Cephalad positioning of the belt over the intended position across the anterior superior iliac spines (which typically occurs in younger children) is thought to be responsible for the observe...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/s00247-002-0779-3

    authors: Emery KH

    更新日期:2002-12-01 00:00:00

  • MRI evaluation of the knee in children with infantile Blount disease: tibial and extra-tibial findings.

    abstract:BACKGROUND:Infantile Blount disease is a developmental condition characterized by disorganized endochondral ossification in the medial aspect of the proximal tibial physis. OBJECTIVE:To describe the MR imaging abnormalities in the proximal tibia, distal femur, menisci and ligaments of children with infantile Blount di...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/s00247-013-2686-1

    authors: Ho-Fung V,Jaimes C,Delgado J,Davidson RS,Jaramillo D

    更新日期:2013-10-01 00:00:00

  • Comparison of helical and conventional chest CT in the uncooperative pediatric patient.

    abstract::The objective of this study was to compare the quality of conventional and helical computed tomography (CT) images in children unable to breath-hold. Sixteen patients (age range 1.1-7.5 years) underwent both conventional and helical chest CT on a General Electric HiSpeed Advantage scanner at a mean study interval of 3...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/BF02021699

    authors: Cox TD,White KS,Weinberger E,Effmann EL

    更新日期:1995-01-01 00:00:00

  • Left aortic arch with congenital isolation of the right subclavian artery.

    abstract::This is the first clinical and angiographic description of congenital subclavian steal in a patient with left aortic arch, isolation of the right subclavian artery, and an aortic diverticulum. ...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/BF01092954

    authors: Garti IJ,Aygen MM

    更新日期:1980-07-01 00:00:00

  • Misleading appearances in pediatric uroradiology.

    abstract::Certain misleading appearances are peculiar to pediatric uroradiology. The most frequently encountered pitfalls are related to the bladder, to vesicoureteral reflux, and to the duplicated collecting system. The bi-chambered nature of the child's bladder, and the rapid settling of contrast material to the most dependen...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/BF01644339

    authors: Lebowitz RL,Avni FE

    更新日期:1980-09-01 00:00:00

  • A proposed radiological classification of childhood intra-thoracic tuberculosis.

    abstract::One of the obstacles in discussing childhood tuberculosis (TB) is the lack of standard descriptive terminology to classify the diverse spectrum of disease. Accurate disease classification is important, because the correct identification of the specific disease entity has definite prognostic significance. Accurate clas...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/s00247-004-1238-0

    authors: Marais BJ,Gie RP,Schaaf HS,Starke JR,Hesseling AC,Donald PR,Beyers N

    更新日期:2004-11-01 00:00:00

  • Gastro-oesophageal intussusception after Nissen-fundoplication.

    abstract::A case of gastro-oesophageal intussusception was reported in 1840 by Von Rokitanski: this is rare, with only two other cases having been reported. In our patient the gastro-oesophageal intussusception followed Nissen fundoplication. ...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/BF02019667

    authors: Post PJ,Robben SG,Meradji M

    更新日期:1990-01-01 00:00:00

  • Is the first urinary infection in childhood a definite indication for radiological examination?

    abstract::The need for X-ray investigations of the urinary tract at the time of the first proven urinary infection, even in older girls, is stressed. This policy is the best way to detect chronic pyelonephritis and congenital anomalies of the urinary tract and provide timely and appropriate treatment. These conclusions are supp...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/BF00972109

    authors: Krepler P,Weisskirchner B,Schroth B

    更新日期:1977-10-28 00:00:00

  • Diagnostic performance of contrast-enhanced MR for acute appendicitis and alternative causes of abdominal pain in children.

    abstract:OBJECTIVE:Unenhanced MRI has emerged as a useful tool for diagnosing pediatric acute appendicitis. The use of contrast-enhanced MRI for diagnosing pediatric appendicitis has not been documented. The purpose of this study is to examine the diagnostic performance of contrast-enhanced MRI for acute appendicitis and altern...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/s00247-014-2952-x

    authors: Koning JL,Naheedy JH,Kruk PG

    更新日期:2014-08-01 00:00:00

  • Mesomelic dysplasia of the upper extremities associated with other abnormalities: a new syndrome?

    abstract::A 3-year-old Algerian boy with unusual facies, mesomelic dysplasia of the upper extremities, meta-epiphyseal changes in the lower extremities and skin dimples is reported. The authors are not able to classify the child's syndrome nosologically. ...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/BF02012398

    authors: Kozlowski K,Bacha L,Brachimi L,Massen R

    更新日期:1993-01-01 00:00:00

  • Cystic liver metastases from extracranial primitive neuroectodermal tumour: a case report.

    abstract::We report a rare case of cystic metastases to the liver from a peripheral primitive neuroectodermal tumour in a child. Ultrasound and CT appearances are described with a discussion on the histological findings and the differential diagnosis. ...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/s002470000347

    authors: Shah BK,McHugh K

    更新日期:2000-12-01 00:00:00

  • Size of the intracranial optic nerve and optic tract in neonates at term-equivalent age at magnetic resonance imaging.

    abstract:BACKGROUND:The expected MRI-based dimensions of the intracranial optic nerve and optic tract in neonates are unknown. OBJECTIVE:To evaluate the sizes of the intracranial optic nerve and optic tract in neonates at term-equivalent age using MRI. MATERIALS AND METHODS:We retrospectively analyzed brain MRI examinations i...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/s00247-015-3495-5

    authors: Oyama J,Mori K,Imamura M,Mizushima Y,Tateishi U

    更新日期:2016-04-01 00:00:00

  • Developing a pediatric endovascular thrombolysis program: a single-center experience.

    abstract::Deep venous thrombosis (DVT) is being increasingly recognized as a significant issue in children. Despite the low incidence of DVT, the risks of pulmonary embolism and death in children are significant. Post-thrombotic syndrome, a syndrome of chronic venous insufficiency, can have long-term adverse consequences in chi...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/s00247-013-2634-0

    authors: Kukreja K,Gruppo R,Chima R,Ristagno R,Racadio J

    更新日期:2013-08-01 00:00:00

  • Neurologic complications of cerebral angiography in childhood moyamoya syndrome.

    abstract::Purpose. To determine the incidence of neurologic complications of cerebral angiography in children with moyamoya syndrome (MMS) as compared to children without MMS. Materials and methods. One-hundred-ninety consecutive cerebral angiograms obtained in 152 children were evaluated. Sixty of these angiograms were obtaine...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/s002470050474

    authors: Robertson RL,Chavali RV,Robson CD,Barnes PD,Eldredge EA,Burrows PE,Scott RM

    更新日期:1998-11-01 00:00:00

  • Colour Doppler ultrasonography replacing surgical exploration for acute scrotum: myth or reality?

    abstract:BACKGROUND:Traditionally, every patient with an acute scrotum needed surgical exploration for definitive exclusion of testicular torsion. OBJECTIVE:In this study, we aimed to evaluate the improved accuracy in clinical diagnosis with colour Doppler Ultrasonography (US) added to normal clinical assessment. MATERIALS AN...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/s00247-005-1411-0

    authors: Lam WW,Yap TL,Jacobsen AS,Teo HJ

    更新日期:2005-06-01 00:00:00

  • Rickets as a complication of intravenous hyperalimentation in infants.

    abstract::Fifteen newborn infants developed roentgenographic evidence of rickets while on long-term intravenous hyperalimentation. In each instance, the initial diagnosis of rickets was suggested on the chest roentgenogram, where characteristic cupped and frayed upper humeral metaphyses were noted; subsequent knee and wrist roe...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/BF02386710

    authors: Binstadt DH,L'Heureux PR

    更新日期:1978-12-04 00:00:00

  • Bone fractures in children undergoing orthotopic liver transplantation.

    abstract::This retrospective study documents the incidence and distribution of fractures in 117 children with end-stage liver disease who underwent orthotopic liver transplantation (OLT) over a 6-year period (1987-1993). Both the pre- and post-OLT phases were included. Nineteen children (16.2 %) sustained a total of 69 fracture...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:

    authors: Hill SA,Kelly DA,John PR

    更新日期:1995-11-01 00:00:00

  • Evaluation of glomerular function in individual kidneys using dynamic magnetic resonance imaging.

    abstract::We used the fast field-echo technique of magnetic resonance (MR) imaging with an intravenous bolus injection of paramagnetic contrast agent to evaluate glomerular function. The time-dependent curves of changes in signal intensity observed in the renal cortex and renal medulla brought about by the paramagnetic contrast...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/BF01395707

    authors: Fukuda Y,Watanabe H,Tomita T,Katayama H,Miyano T,Yabuta K

    更新日期:1996-01-01 00:00:00

  • CT demonstration of cortical nephrocalcinosis in congenital oxalosis.

    abstract::The clinical, pathologic and roentgenographic features of a case of congenital oxalosis are discussed and contrasted to the more common forms of primary oxalosis. The ease of demonstration of the cortical deposition of calcium oxalate crystals on the CT scanner is reported. ...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/BF01001753

    authors: Luers PR,Lester PD,Siegler RL

    更新日期:1980-11-01 00:00:00

  • Optimization of a fluoroscope to reduce radiation exposure in pediatric imaging.

    abstract:BACKGROUND:A new children's hospital provided the impetus to investigate radiation dose and image quality in a fluoroscope that was specially engineered for pediatric fluoroscopy. Radiation protection management recommends radiation exposures that are as low as reasonably achievable, while still maintaining diagnostic ...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/s002470050728

    authors: Brown PH,Thomas RD,Silberberg PJ,Johnson LM

    更新日期:2000-04-01 00:00:00

  • Utilization of low-dose multidetector CT and virtual bronchoscopy in children with suspected foreign body aspiration.

    abstract:BACKGROUND:Foreign body aspiration is common in children, especially those under 3 years of age. Chest radiography and CT are the main imaging modalities for the evaluation of these children. Management of children with suspected foreign body aspiration (SFBA) mainly depends on radiological findings. OBJECTIVE:To inve...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/s00247-006-0331-y

    authors: Adaletli I,Kurugoglu S,Ulus S,Ozer H,Elicevik M,Kantarci F,Mihmanli I,Akman C

    更新日期:2007-01-01 00:00:00

  • Hemorrhage in cavum septi pellucidi.

    abstract::One case of hemorrhage in the cavum septi pellucidi (CSP) is presented. This unusual location of intracranial hemorrhage was demonstrated by cranial sonography in a premature neonate. ...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/BF02386822

    authors: Vade A,McKusick M,Michael A

    更新日期:1986-01-01 00:00:00

  • Diagnostic errors by radiology residents in interpreting pediatric radiographs in an emergency setting.

    abstract:BACKGROUND:There are few data regarding the frequency and type of diagnostic errors made by radiology residents and fellows ("trainees"). However, increasing interest in reducing medical errors highlights the need to analyze which areas of medical knowledge are most problematic for physicians-in-training, including rad...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/s00247-004-1150-7

    authors: Halsted MJ,Kumar H,Paquin JJ,Poe SA,Bean JA,Racadio JM,Strife JL,Donnelly LF

    更新日期:2004-04-01 00:00:00

  • Traumatic abdominal aortic dissection in a 16-month-old child.

    abstract::Abdominal aortic injury after blunt trauma is rare in the pediatric population. There have been fewer than 20 reported cases in the literature since 1960, and most were the result of motor vehicle collisions. We report the case of a 16-month-old boy who is the youngest reported patient to sustain this type of injury. ...

    journal_title:Pediatric radiology

    pub_type: 杂志文章,评审

    doi:10.1007/s00247-009-1224-7

    authors: Heck JM,Bittles MA

    更新日期:2009-07-01 00:00:00

  • Vertical expandable prosthetic titanium rib (VEPTR): a review of indications, normal radiographic appearance and complications.

    abstract::Vertical expandable prosthetic titanium rib (VEPTR) is increasingly used in the treatment of thoracic insufficiency, idiopathic and neuromuscular scoliosis and chest wall defects in children. In contrast to spinal fusion surgery, the VEPTR allows for growth while stabilizing the deformity. We illustrate the common ind...

    journal_title:Pediatric radiology

    pub_type: 杂志文章,评审

    doi:10.1007/s00247-014-3128-4

    authors: Parnell SE,Effmann EL,Song K,Swanson JO,Bompadre V,Phillips GS

    更新日期:2015-04-01 00:00:00

  • Preoperative ultrasonographic diagnosis of a parathyroid adenoma in a child.

    abstract::The case of a young boy with primary hyperparathyroidism due to an adenoma is reported. The tumor was localized by ultrasonography, and a close correlation between the image and the surgical findings was found. Since primary hyperparathyroidism in children under 15 years of age is frequently due to adenomata larger th...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/BF02386732

    authors: Rodríguez-Cueto G,Manzano-Sierra C,Villalpando-Hernandez S

    更新日期:1984-01-01 00:00:00

  • Subgaleal hematoma presenting as a manifestation of Factor XIII deficiency.

    abstract::Extracranial hematoma without significant head trauma is uncommon. We discuss a 9-year-old girl who presented with sudden head swelling, bilateral proptosis, extraocular muscle palsy, and progressive visual disturbance after hair braiding. The diagnosis of a large subgaleal hematoma with extension into the superior as...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/s00247-009-1176-y

    authors: Kim D,Taragin B

    更新日期:2009-06-01 00:00:00

  • Structural and perfusion magnetic resonance imaging of the lung in cystic fibrosis.

    abstract:BACKGROUND:Because of its absence of ionising radiation and possibility for obtaining functional information, MRI is promising for assessing lung disease in children who require repetitive imaging for long-term follow-up. OBJECTIVE:To describe MRI findings in children with cystic fibrosis and evaluate semi-quantitativ...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/s00247-017-4021-8

    authors: Amaxopoulou C,Gnannt R,Higashigaito K,Jung A,Kellenberger CJ

    更新日期:2018-02-01 00:00:00

  • Digital atlas of fetal brain MRI.

    abstract:BACKGROUND:Fetal MRI can be performed in the second and third trimesters. During this time, the fetal brain undergoes profound structural changes. Interpretation of appropriate development might require comparison with normal age-based models. Consultation of a hard-copy atlas is limited by the inability to compare mul...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/s00247-009-1411-6

    authors: Chapman T,Matesan M,Weinberger E,Bulas DI

    更新日期:2010-02-01 00:00:00