Abstract:
BACKGROUND:Focal liver lesions are common in children and adults after Fontan procedures. OBJECTIVE:To explore the relationship between liver shear stiffness, using magnetic resonance (MR) elastography, and the presence of focal liver lesions in patients after Fontan procedures (total cavopulmonary anastomosis). MATERIALS AND METHODS:The retrospective study was approved by the institutional review board and the requirement for informed consent was waived. By searching institutional electronic medical records, we identified all patients with a history of Fontan palliation of congenital heart disease who had undergone same-day liver MR elastography and liver MRI without and with intravenous contrast material between January 2012 and December 2017. Using imaging reports, patients were placed into two groups: 1) no focal liver lesions and 2) one or more focal liver lesions. Patient age, sex, mean liver shear stiffness (kPa) and maximum single anatomical level liver shear stiffness (kPa) were recorded. The Mann-Whitney U test was used to compare age and liver stiffness between groups, while the Fisher exact test was used to assess the impact of gender on liver lesions. RESULTS:Forty-eight patients met study inclusion criteria; 33 (69%) had one or more focal liver lesions. The median age was 20.0 years (IQR [interquartile range]: 10.8-29.1 years) for patients without liver lesions and 19.9 years (IQR: 17.2-27.0 years) for patients with liver lesions (P=0.49). Eleven of 21 male patients (52.4%) had liver lesions compared to 22 of 27 female patients (81.5%) (P=0.058). Mean (4.62 kPa [IQR: 4.10-5.59 kPa] vs. 4.10 kPa [IQR: 3.44-4.80 kPa]; P=0.02) and maximum (5.53 kPa [IQR: 4.64-6.56 kPa] vs. 4.50 kPa [IQR: 3.82-5.35 kPa]; P=0.009) liver stiffness were significantly higher in patients without liver lesions as compared to patients with liver lesions. CONCLUSION:Our study demonstrated a significant negative association between focal liver lesions and increased liver stiffness in patients following Fontan procedures.
journal_name
Pediatr Radioljournal_title
Pediatric radiologyauthors
Diaz ES,Dillman JR,Veldtman GR,Trout ATdoi
10.1007/s00247-018-4264-zsubject
Has Abstractpub_date
2019-01-01 00:00:00pages
99-104issue
1eissn
0301-0449issn
1432-1998pii
10.1007/s00247-018-4264-zjournal_volume
49pub_type
杂志文章abstract:BACKGROUND:Data suggest an increased risk of thyroid dysfunction following iodine-based contrast material (IBCM) in children. OBJECTIVE:To estimate the prevalence of thyroid stimulating hormone (TSH) abnormalities following exposure to a single dose of intravenous IBCM during computed tomography (CT) in young children...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-020-04881-0
更新日期:2020-11-17 00:00:00
abstract::A retrospective study was performed of 39 children at the Children's Memorial Hospital, Chicago, Illinois, who underwent technetium-99m glucoheptonate (99mTcGH) scintigraphy for evaluation of possible urinary tract infection. Clinical and laboratory criteria classified the children as having pyelonephritis, cystitis, ...
journal_title:Pediatric radiology
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abstract::A 14-year-old girl presented with symptoms and signs of left otomastoiditis and meningitis. CT and MRI revealed a largely expanded cavum septum pellucidum with enhancing walls and findings suggesting left otomastoiditis and meningitis. At surgery, an abscess was found within the cavum septum pellucidum. Five similar c...
journal_title:Pediatric radiology
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doi:10.1007/s00247-003-0925-6
更新日期:2003-07-01 00:00:00
abstract::A 3-year-old Algerian boy with unusual facies, mesomelic dysplasia of the upper extremities, meta-epiphyseal changes in the lower extremities and skin dimples is reported. The authors are not able to classify the child's syndrome nosologically. ...
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abstract:BACKGROUND:The expected MRI-based dimensions of the intracranial optic nerve and optic tract in neonates are unknown. OBJECTIVE:To evaluate the sizes of the intracranial optic nerve and optic tract in neonates at term-equivalent age using MRI. MATERIALS AND METHODS:We retrospectively analyzed brain MRI examinations i...
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更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:Spinal imaging has been a neglected part of abusive head trauma (AHT) imaging. As most of the radiographs and CT spine are negative in AHT in infants, the cervical spine is assumed to be normal. There is increasing evidence in the role of injury to brainstem and cervical cord in the pathogenesis of AHT. In a...
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abstract:BACKGROUND:Various reports support the use of cervical spine (c-spine) CT over conventional radiography in screening of c-spine injury. Interest now exists in diagnostic radiation-induced morbidity. OBJECTIVE:To estimate excess relative risk for developing cancer from c-spine high-resolution CT radiation exposure. MA...
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abstract::Trichorhinophalangeal syndrome type II is a rare genetic disorder with the few published case reports mainly reporting the radiographic skeletal manifestations. There are no published imaging reports of long bone cysts involving multiple bones in this condition. We report a unique case of bone cysts involving multiple...
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journal_title:Pediatric radiology
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pub_type: 杂志文章,评审
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更新日期:2010-06-01 00:00:00
abstract::We present a pictorial review of neonatal ischemic brain injury and look at its pathophysiology, imaging features and differential diagnoses from a radiologist's perspective. The concept of perinatal stroke is defined and its distinction from hypoxic-ischemic injury is emphasized. A brief review of recent imaging adva...
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更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:Demand for pediatric cardiac computed tomography (CT) angiography is increasing due to recent advances that reduce the need for sedation and radiation exposure while enhancing diagnostic accuracy. This has resulted in the increasing use of cardiac CT angiography emergently during weekends and after hours. Th...
journal_title:Pediatric radiology
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doi:10.1007/s00247-020-04659-4
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:Patent ductus arteriosus (PDA) stent placement in infants with ductal-dependent pulmonary blood flow is being increasingly used in clinical practice. OBJECTIVE:To correlate computed tomographic (CT) angiography morphology and length of the PDA with catheter angiography and its relation to eventual PDA stent...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-020-04624-1
更新日期:2020-05-01 00:00:00
abstract::One of the obstacles in discussing childhood tuberculosis (TB) is the lack of standard descriptive terminology to classify the diverse spectrum of disease. Accurate disease classification is important, because the correct identification of the specific disease entity has definite prognostic significance. Accurate clas...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-004-1238-0
更新日期:2004-11-01 00:00:00
abstract:OBJECTIVE:To offer a descriptive review which characterizes and evaluates the significance of local physeal widening, (cartilaginous signal extending from the physis into the adjacent metaphysis), identified on magnetic resonance (MR) imaging. MATERIALS AND METHODS:MR images (recollected from exams performed between 1...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470050206
更新日期:1997-08-01 00:00:00
abstract::Transient cortical blindness is reported to occur in 0.3% to 1% of cerebral angiography procedures. It develops within minutes of contrast medium injection and lasts for up to several days. We report a long episode of transient cortical blindness in a 17-year-old boy with cerebellar haemangioblastoma, which started du...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-009-1335-1
更新日期:2009-11-01 00:00:00
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doi:10.1007/s00247-008-0878-x
更新日期:2008-11-01 00:00:00
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更新日期:2019-06-01 00:00:00
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更新日期:1990-01-01 00:00:00
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更新日期:1977-09-01 00:00:00
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更新日期:1998-12-01 00:00:00
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pub_type: 杂志文章,已发布勘误
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更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:Phalangeal microgeodic syndrome is an uncommon benign self-limiting condition that often occurs during cold weather. The etiology and the pathogenesis of the disease remain unclear. OBJECTIVE:To report a series of children with phalangeal microgeodic syndrome. MATERIALS AND METHODS:Twenty children with pha...
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更新日期:2020-09-01 00:00:00
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更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:Computed-tomography-guided interventions are attractive for tissue sampling of pediatric bone lesions; however, it comes with exposure to ionizing radiation, inherent to CT and magnified by multiple passes during needle localization. OBJECTIVE:We evaluate a method of CT-guided bone biopsy that minimizes ion...
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更新日期:2013-10-01 00:00:00
abstract::Foreign bodies, whether ingested, aspirated or retained in the soft tissues, are a particular hazard to pediatric patients. Ornamentation associated with the winter holidays is an uncommon source of foreign bodies in children, and many of these foreign bodies have a distinct appearance on imaging. Knowledge of these a...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/s00247-014-3192-9
更新日期:2014-12-01 00:00:00
abstract::This paper is a comprehensive review of the Doppler waveform appearance of ureteric jets. Six jet waveform patterns have been identified: monophasic, biphasic, triphasic, polyphasic, square and continuous. Details of the physical properties of jet patterns and their changes under various physiological conditions are i...
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更新日期:2007-05-01 00:00:00