Abstract:
BACKGROUND:Focal liver lesions are common in children and adults after Fontan procedures. OBJECTIVE:To explore the relationship between liver shear stiffness, using magnetic resonance (MR) elastography, and the presence of focal liver lesions in patients after Fontan procedures (total cavopulmonary anastomosis). MATERIALS AND METHODS:The retrospective study was approved by the institutional review board and the requirement for informed consent was waived. By searching institutional electronic medical records, we identified all patients with a history of Fontan palliation of congenital heart disease who had undergone same-day liver MR elastography and liver MRI without and with intravenous contrast material between January 2012 and December 2017. Using imaging reports, patients were placed into two groups: 1) no focal liver lesions and 2) one or more focal liver lesions. Patient age, sex, mean liver shear stiffness (kPa) and maximum single anatomical level liver shear stiffness (kPa) were recorded. The Mann-Whitney U test was used to compare age and liver stiffness between groups, while the Fisher exact test was used to assess the impact of gender on liver lesions. RESULTS:Forty-eight patients met study inclusion criteria; 33 (69%) had one or more focal liver lesions. The median age was 20.0 years (IQR [interquartile range]: 10.8-29.1 years) for patients without liver lesions and 19.9 years (IQR: 17.2-27.0 years) for patients with liver lesions (P=0.49). Eleven of 21 male patients (52.4%) had liver lesions compared to 22 of 27 female patients (81.5%) (P=0.058). Mean (4.62 kPa [IQR: 4.10-5.59 kPa] vs. 4.10 kPa [IQR: 3.44-4.80 kPa]; P=0.02) and maximum (5.53 kPa [IQR: 4.64-6.56 kPa] vs. 4.50 kPa [IQR: 3.82-5.35 kPa]; P=0.009) liver stiffness were significantly higher in patients without liver lesions as compared to patients with liver lesions. CONCLUSION:Our study demonstrated a significant negative association between focal liver lesions and increased liver stiffness in patients following Fontan procedures.
journal_name
Pediatr Radioljournal_title
Pediatric radiologyauthors
Diaz ES,Dillman JR,Veldtman GR,Trout ATdoi
10.1007/s00247-018-4264-zsubject
Has Abstractpub_date
2019-01-01 00:00:00pages
99-104issue
1eissn
0301-0449issn
1432-1998pii
10.1007/s00247-018-4264-zjournal_volume
49pub_type
杂志文章abstract::A case of spontaneous disappearance of an intrathoracic meningocele following insertion of a ventriculo-venous shunt is reported. The shunt was performed for treatment of hydrocephalus secondary to Arnold-Chiari malformation. The intrathoracic meningocele reappeared when the shunt obstructed and decreased in size when...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF00973987
更新日期:1977-03-17 00:00:00
abstract::Shaken-baby syndrome (SBS) is a type of child abuse caused by violent shaking of an infant, with or without impact, and characterized by subdural hematomas, retinal hemorrhages, and occult bone fractures. Parenchymal brain lesions in SBS may be missed or underestimated on CT scans, but can be detected at an earlier st...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-003-1025-3
更新日期:2003-12-01 00:00:00
abstract::Pyloric atresia is an uncommon congenital gastric outlet obstruction, accounting for only 1% of gastrointestinal atresias. Up to 55% of cases have associated anomalies, the most common of which is epidermolysis bullosa. Fetal MRI findings of the epidermolysis bullosa-pyloric atresia association have not been previousl...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-013-2737-7
更新日期:2013-12-01 00:00:00
abstract:BACKGROUND:Subglottic haemangioma causes progressive and life-threatening stridor, typically manifesting at age 2-3 months. Standard diagnosis is by laryngoscopy. Larynx sonography is rarely used but allows assessment of the presence and extension of a mass that impinges on the subglottic airway. The additional use of ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-011-2213-1
更新日期:2011-11-01 00:00:00
abstract:BACKGROUND:Acute pelvic pyomyositis is uncommon in non-tropical areas. OBJECTIVE:To summarize the clinical and MR findings in children with acute pelvic pyomyositis. MATERIALS AND METHODS:We retrospectively identified 20 children (mean age 9.4 years) who were evaluated by MR and diagnosed with acute pelvis pyomyositi...
journal_title:Pediatric radiology
pub_type: 临床试验,杂志文章
doi:10.1007/s00247-005-0082-1
更新日期:2006-04-01 00:00:00
abstract:OBJECTIVE:We prospectively surveyed patients with myelomeningocele who presented in our department over a 3-month period to determine the frequency of latex allergy in this population. MATERIALS AND METHODS:A questionnaire assessed history of allergy to latex and attitudes toward and use or avoidance of latex-containi...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF01377199
更新日期:1996-07-01 00:00:00
abstract:BACKGROUND:Percutaneous arterial closure devices have increasingly entered clinical practice to assist in achieving femoral arterial access site hemostasis. Prior studies have demonstrated the safety and efficacy of several arterial closure devices in adults. OBJECTIVE:To evaluate the efficacy of using an arterial clo...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-012-2606-9
更新日期:2013-06-01 00:00:00
abstract::Osteogenic sarcoma arising in the spine, and in particular the neural arch, is rare. We present the case of a 4-year-old girl with an osteogenic sarcoma arising in the left transverse process of the second lumbar vertebra. The child received chemotherapy and delayed surgical excision was performed following a favourab...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02020853
更新日期:1995-01-01 00:00:00
abstract::The anatomical anomalies that characterize septo-optic-dysplasia (deMorsier Syndrome) are variable and often subtle. We report imaging studies of nine patients with septo-optic-dysplasia which provide radiologic and ultrasonographic clues to this disorder. In addition, we propose that cerebral schizencephaly may be a ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02388642
更新日期:1989-01-01 00:00:00
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journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470050591
更新日期:1999-04-01 00:00:00
abstract::Atlas anomalies in terms of clefts and aplasia are rare. They can sometimes simulate fractures and need further evaluation. Imaging in terms of CT and MR can help resolve diagnostic confusion and also outline associated neurological involvement. A rare anomaly of anterior and posterior atlas arch, previously unclassif...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470100542
更新日期:2001-11-01 00:00:00
abstract:BACKGROUND:Transient synovitis is the most common cause of acute hip pain in children. However, MR imaging findings in transient synovitis and the role of MR imaging in differentiating transient synovitis from septic arthritis have not been fully reported. OBJECTIVE:To describe the MR findings of transient synovitis a...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-006-0289-9
更新日期:2006-11-01 00:00:00
abstract::Abdominal trauma is a leading cause of death in children older than 1 year of age. The spleen is the most common organ injured following blunt abdominal trauma. Pediatric trauma patients present unique clinical challenges as compared to adults, including different mechanisms of injury, physiologic responses, and indic...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/s00247-009-1336-0
更新日期:2009-09-01 00:00:00
abstract::Congenital solitary nonparasitic cysts of the liver (CSNCL) are extremely rare causes of abdominal masses in newborns and infants. We describe a cystic abdominal mass virtually all extrahepatic in a newborn that proved to be a CSNCL. ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02013009
更新日期:1992-01-01 00:00:00
abstract::Gadolinium-based contrast agents can increase the accuracy and expediency of an MRI examination. However the benefits of a contrast-enhanced scan must be carefully weighed against the well-documented risks associated with administration of exogenous contrast media. The purpose of this review is to discuss commercially...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/s00247-017-3806-0
更新日期:2017-05-01 00:00:00
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journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF00975350
更新日期:1976-04-14 00:00:00
abstract::We report a neonate with antenatal imaging features suggestive of CLOVES syndrome. Postnatal clinical and imaging findings confirmed the diagnosis, with the constellation of truncal overgrowth, cutaneous capillary malformation, lymphatic and musculoskeletal anomalies. The clinical, radiological and histopathological f...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-010-1559-0
更新日期:2010-08-01 00:00:00
abstract::Classic metaphyseal lesions associated with childbirth are rare. We report a distal tibial metaphyseal fracture following a difficult breech delivery. Classic metaphyseal fractures are considered highly specific injuries associated with non-accidental trauma. This case depicts a classic metaphyseal lesion sustained du...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-019-04490-6
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:Internal hernias are uncommon in children and their clinical and imaging findings have not been widely addressed. OBJECTIVE:To determine the spectrum of clinical and imaging findings of internal hernia (IH) in children and to highlight diagnostic features. MATERIALS AND METHODS:Review of clinical, imaging ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-011-2158-4
更新日期:2011-12-01 00:00:00
abstract::Kidney length (KL), renal area and renal parenchymal area were measured on i.v. urograms of 255 children without apparent kidney disease age 0 to 14 years. These parameters were compared with age, body height, body surface area and the distance between the 1st and 4th lumbar vertebral body. In addition, renal parenchy...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF01464310
更新日期:1980-04-01 00:00:00
abstract::A 3-year-old Algerian boy with unusual facies, mesomelic dysplasia of the upper extremities, meta-epiphyseal changes in the lower extremities and skin dimples is reported. The authors are not able to classify the child's syndrome nosologically. ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02012398
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abstract::Imaging plays a major role in the diagnostic work-up of children with hepatobiliary or pancreatic diseases. It consists mainly of US, CT and MRI, with US and MRI being the preferred imaging modalities because of the lack of ionizing radiation. In this review the technique of US, CT and MRI in children will be addresse...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
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journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02011950
更新日期:1993-01-01 00:00:00
abstract::Neonatal goiter is a rare cause of a neck mass and stridor. Often, the diagnosis can be made on clinical grounds exclusively, but there may be times when a neck mass becomes a diagnostic dilemma. There are several different imaging modalities available to the clinician that are useful in the rapid diagnosis of neonata...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF01405300
更新日期:1996-01-01 00:00:00
abstract::Gallbladder volvulus in children is rare. Pre-operative diagnosis is considered difficult because of the nonspecific symptoms and inflammatory blood analysis findings. Sometimes diagnosis is confirmed at laparotomy. Many reports mention that the chief complaints of this disease are sudden and severe abdominal pain. We...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-010-1753-0
更新日期:2011-01-01 00:00:00
abstract::Image quality takes on different perspectives and meanings when associated with the concept of as low as reasonably achievable (ALARA), which is chiefly focused on radiation dose delivered as a result of a medical imaging procedure. ALARA is important because of the increased radiosensitivity of children to ionizing r...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/s00247-004-1268-7
更新日期:2004-10-01 00:00:00
abstract::We present a rare case of a broken umbilical artery catheter retrieved via a transumbilical approach with biopsy forceps. ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:
更新日期:1995-11-01 00:00:00
abstract::Neonatal cerebral MR imaging is a sensitive technique for evaluating brain injury in the term and preterm infant. In term encephalopathic infants, MR imaging reliably detects not only the pattern of brain injury but might also provide clues about the timing of injury. In premature infants, MR imaging has surpassed US ...
journal_title:Pediatric radiology
pub_type: 杂志文章,实务指引
doi:10.1007/s00247-007-0705-9
更新日期:2008-03-01 00:00:00
abstract::Fibroblast growth factor receptor mutations cause some of the main short-limb skeletal dysplasias and craniosynostosis syndromes, including achondroplasia, hypochondroplasia, thanatophoric dysplasia, Apert syndrome, Crouzon syndrome, Pfeiffer syndrome, and Jackson-Weiss syndrome. Much work remains to be done in unrave...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
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更新日期:1997-05-01 00:00:00
abstract::We describe a 4-year-old girl with an inflammatory pseudotumour of the pancreas, which was preceded by varicella-zoster infection. Inflammatory pseudotumour may involve a variety of tissues, the lungs and liver being typical sites of predilection. Imaging and laboratory tests are nonspecific, and for this reason the d...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470000331
更新日期:2000-11-01 00:00:00