Abstract:
:Ongoing genetic and epigenetic research involving DNA methylation, salivary biomarkers, wild-type p53 tumor suppressor gene proteins, and HPV oncogenes are being directed at identification and treatment of dysplastic and malignant squamous cell mucosal lesions. Research is being conducted to improve immunotherapy drug response rates by increasing the amount of inflammation within the tumor microenvironment. Ongoing research is focused on the application of the antidiabetic drug metformin for the prevention and management of oral squamous cell dysplastic lesions. Professional and nonprofit cancer support organizations are essential for furthering education and research within the area of head and neck cancer.
journal_name
Oral Maxillofac Surg Clin North Amjournal_title
Oral and maxillofacial surgery clinics of North Americaauthors
Lubek JEdoi
10.1016/j.coms.2018.06.007subject
Has Abstractpub_date
2018-11-01 00:00:00pages
459-469issue
4eissn
1042-3699issn
1558-1365pii
S1042-3699(18)30059-1journal_volume
30pub_type
杂志文章,评审abstract::Digital imaging technology and refined software programs have significantly improved a clinician's ability to assess and evaluate anatomic structures and quantify both defect size and required graft volume. This article summarizes the computed tomography-based technology used in these applications to illustrate their ...
journal_title:Oral and maxillofacial surgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.coms.2019.03.008
更新日期:2019-08-01 00:00:00
abstract::This article addresses the incidence of specific complications and, where possible, offers a preventive or management strategy. Injuries of the inferior alveolar and lingual nerves are significant issues that are discussed separately in this text. Surgical removal of third molars is often associated with postoperative...
journal_title:Oral and maxillofacial surgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.coms.2006.11.013
更新日期:2007-02-01 00:00:00
abstract::The field of skin resurfacing is undergoing rapid evolution with many new technologies that have developed, providing more choices for physicians and patients. Knowing the potential adverse effects associated with each skin resurfacing modality is paramount in selecting the appropriate approach for each candidate, the...
journal_title:Oral and maxillofacial surgery clinics of North America
pub_type: 杂志文章
doi:10.1016/j.coms.2008.11.002
更新日期:2009-02-01 00:00:00
abstract::Asymptomatic third molars may have associated periodontal pathology that may not be limited to the third molar region and have a negative impact on systemic health. Third molars should be considered for removal when there is clinical, radiographic, or laboratory evidence of acute or chronic periodontitis, caries, peri...
journal_title:Oral and maxillofacial surgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.coms.2006.11.007
更新日期:2007-02-01 00:00:00
abstract::The submental island flap is a local flap that is simple to raise and is useful for oral and lower face reconstruction of soft tissue defects. It is based on the submental artery and the facial vein. Using a retrograde flow design allows for reconstruction of forehead, temporal, and periorbital defects. Raising the fl...
journal_title:Oral and maxillofacial surgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.coms.2014.05.005
更新日期:2014-08-01 00:00:00
abstract::Fractures of the larynx are uncommon injuries that may be associated with maxillofacial trauma. Clinicians treating maxillofacial injuries should be familiar with the signs and symptoms of laryngeal fractures and with proper airway management. A timely evaluation of the larynx, rapid airway intervention, and proper su...
journal_title:Oral and maxillofacial surgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.coms.2008.03.004
更新日期:2008-08-01 00:00:00
abstract::The transverse dimension is a critical component of comprehensive treatment in orthognathic surgery. Several treatment approaches exist and the team must consider the patient's needs, desires, and limitations when working to correct the malocclusion. Treatment approaches may include only orthodontic expansion or rapid...
journal_title:Oral and maxillofacial surgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.coms.2019.08.007
更新日期:2020-02-01 00:00:00
abstract::Because of the common shared risk factors of smoking and heavy alcohol consumption, literature involving oropharyngeal squamous cell carcinoma (OPSCC) is often combined with oral squamous cell carcinoma. Human papilloma virus is now confirmed to be a major risk factor of OPSCC with its distinct epidemiology and favora...
journal_title:Oral and maxillofacial surgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.coms.2017.03.004
更新日期:2017-08-01 00:00:00
abstract::This article briefly reviews some of the most common skin lesions in the head and neck of a child. Benign "lumps and bumps" are very common in children and it is prudent for the pediatric maxillofacial surgeon to be familiar with their presentation, workup (including radiographic studies), and definitive surgical mana...
journal_title:Oral and maxillofacial surgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.coms.2012.04.001
更新日期:2012-08-01 00:00:00
abstract::The esthetic stigmata and functional impairments associated with craniofacial deformities have long challenged surgeons in the management of deficiencies of the middle third of the face. By their very nature, craniofacial anomalies are repetitive patterns of deformity that affect the different functional and esthetic ...
journal_title:Oral and maxillofacial surgery clinics of North America
pub_type: 杂志文章
doi:10.1016/j.coms.2004.08.001
更新日期:2004-11-01 00:00:00
abstract::There is a recognized need to reconstruct and restore complex craniomaxillofacial soft tissues. The objective of this article is to focus on the role that tissue engineering/regenerative medicine can play in addressing various barriers (vascularity, tissue bulk, volitional control, and esthetics) and impediments (timi...
journal_title:Oral and maxillofacial surgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.coms.2016.08.007
更新日期:2017-02-01 00:00:00
abstract::Pediatric odontogenic tumors are rare, and are often associated with impacted teeth. Although they can develop anywhere in the jaws, odontogenic tumors mainly occur in the posterior mandible. This article discusses the diagnosis and treatment of the most common pediatric odontogenic tumors, such as ameloblastoma, kera...
journal_title:Oral and maxillofacial surgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.coms.2015.08.003
更新日期:2016-02-01 00:00:00
abstract::The temporomandibular joint (TMJ) is one of the many joints involved in the inflammatory arthritides. As imaging of joints has developed, so have the data regarding extent and prevalence of TMJ involvement in these diseases. TMJ disease is especially prevalent in juvenile arthritis. The adult and pediatric inflammator...
journal_title:Oral and maxillofacial surgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.coms.2014.09.001
更新日期:2015-02-01 00:00:00
abstract::To prepare global surgeons, academic institutions have created training programs that provide opportunities to develop foundational clinical knowledge, pursue academic inquiry, build surgical infrastructure and capacity, and become advocates and collaborators in resource-limited settings. Academic institutions can cre...
journal_title:Oral and maxillofacial surgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.coms.2020.04.005
更新日期:2020-08-01 00:00:00
abstract::The authors review the clinical presentation, diagnostic evaluation, and treatment modalities for salivary gland enlargement in an HIV-infected population. Because this can occasionally be the presenting clinical symptom of HIV infection, it is important for the oral/maxillofacial surgeon to diagnose and manage HIV sa...
journal_title:Oral and maxillofacial surgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.coms.2009.04.002
更新日期:2009-08-01 00:00:00
abstract::Patients undergoing treatment of head and neck cancer risk developing significant acute and chronic changes that affect the hard and soft tissue of the oral cavity and the head and neck region. This article discusses considerations and recommendations for patients before, during, and after treatment of head and neck c...
journal_title:Oral and maxillofacial surgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.coms.2018.06.006
更新日期:2018-11-01 00:00:00
abstract::Hair loss affects more than 1.2 billion people worldwide. As the technology and artistry of hair restoration surgery has improved including natural results, so too has the popularity of this procedure. As with any other surgical procedure, complications may occur and this presents a major challenge for the surgeon and...
journal_title:Oral and maxillofacial surgery clinics of North America
pub_type: 杂志文章
doi:10.1016/j.coms.2008.10.010
更新日期:2009-02-01 00:00:00
abstract::Postoperative bone healing after oral surgical procedures occurs uneventfully in most cases. However, in certain patients, the normal process of healing can be delayed and, in some cases, often because of multiple coexisting factors, the sites can become infected, with extension of the infection into medullary bone. T...
journal_title:Oral and maxillofacial surgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.coms.2011.04.005
更新日期:2011-08-01 00:00:00
abstract::The health care industry and delivery systems are placing greater emphasis on making their organizations safe. They do this by cultivating a culture of safety to help anticipate and prevent injuries and documenting and investigating injuries to develop prevention protocols. Many of the strategies used in the hospital ...
journal_title:Oral and maxillofacial surgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.coms.2015.04.008
更新日期:2015-08-01 00:00:00
abstract::Most patients who seek appearance-enhancing medical treatments report some degree of body image dissatisfaction, which is believed to motivate the pursuit of these treatments. However, patients with extreme body image dissatisfaction may be suffering from a psychiatric disorder known as body dysmorphic disorder (BDD)....
journal_title:Oral and maxillofacial surgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.coms.2010.07.002
更新日期:2010-11-01 00:00:00
abstract::Condylar hyperplasia (CH) is a progressive and pathologic overgrowth of either or both mandibular condyles, which can affect the neck, ramus, or body of the mandible. It may lead to facial asymmetry, malocclusion, speech, and masticatory problems. Identifying the specific type of condylar hyperplasia is crucial. Seria...
journal_title:Oral and maxillofacial surgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.coms.2014.09.011
更新日期:2015-02-01 00:00:00
abstract::Health disparities in the United States have been well documented over the past several decades and continue to affect the American population. As the world becomes more diverse, it is imperative that the health care professional workforce is trained to care for the diversifying patient population, striving to improve...
journal_title:Oral and maxillofacial surgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.coms.2020.04.006
更新日期:2020-08-01 00:00:00
abstract::This article reviews three poorly recognized yet relatively common presentations of hyperactive orofacial movement disorders: oromandibular dystonia, orofacial dyskinesia, and drug-induced extrapyramidal syndrome reactions. Orofacial movement disorders are often misdiagnosed as temporomandibular disorders, hence under...
journal_title:Oral and maxillofacial surgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.coms.2007.12.010
更新日期:2008-05-01 00:00:00
abstract::Coronectomy is considered in patients older than 25, where there is an intimate relationship between the roots of a retained lower third molar (occasionally second or first molars) and the inferior alveolar nerve, in noncontraindicated circumstances. It may be used on younger patients with a medium to high risk of inf...
journal_title:Oral and maxillofacial surgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.coms.2015.04.003
更新日期:2015-08-01 00:00:00
abstract::To thoroughly understand the biology of any lesion and render the appropriate management, clear and accurate definitions are paramount. For benign cysts and tumors of the oral maxillofacial region, an accurate depiction of these lesions needs to be elucidated to provide both the treating surgeon and the patient with a...
journal_title:Oral and maxillofacial surgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.coms.2012.01.007
更新日期:2012-05-01 00:00:00
abstract::The practicing oral and maxillofacial surgeon treating patients with oroantral communication (OAC)/oroantral fistulas should be familiar and competent with the various treatment options available. Multiple techniques are available from purely soft tissue flaps, which have proved to be successful over time, to a combin...
journal_title:Oral and maxillofacial surgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.coms.2012.01.015
更新日期:2012-05-01 00:00:00
abstract::Magnetic resonance imaging (MRI) is the modality of choice to identify intracranial or perineural spread from a head and neck primary tumor. Perineural spread is a form of metastatic disease in which primary tumors spread along neural pathways. Orbital cellulitis is a sight-threatening, and potentially life-threatenin...
journal_title:Oral and maxillofacial surgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.coms.2014.03.002
更新日期:2014-05-01 00:00:00
abstract::This article discusses the recent advances and basic concepts of skeletal anchorage devices of various types and reviews the current literature on their use. Temporary skeletal anchorage devices allow orthodontic movements that were previously thought to be difficult if not impossible. Much like the concepts introduce...
journal_title:Oral and maxillofacial surgery clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.coms.2009.10.011
更新日期:2010-02-01 00:00:00
abstract::In the post-World War I antibiotic era, the prevalence of central nervous system (CNS) infections is estimated to be 1 per 100,000 population. The literature is replete with anecdotal case reports of CNS infections of apparent dental etiology. Conversely, it is widely cited that the incidence of CNS infection of denta...
journal_title:Oral and maxillofacial surgery clinics of North America
pub_type: 杂志文章
doi:10.1016/j.coms.2011.08.001
更新日期:2011-11-01 00:00:00
abstract::The safe and efficient use of outpatient surgical anesthesia modalities is a significant part of the training and expertise of the oral and maxillofacial surgeon. Although adverse outcomes are rare, they can have considerable traumatic psychological and professional consequences for the surgeon involved. The goal of t...
journal_title:Oral and maxillofacial surgery clinics of North America
pub_type: 杂志文章
doi:10.1016/j.coms.2013.03.006
更新日期:2013-08-01 00:00:00