Genetic influences on delayed reward discounting: A genome-wide prioritized subset approach.

abstract：:The high comorbidity of posttraumatic stress disorder (PTSD) and alcohol dependence (AD) has been firmly established. Although laboratory studies have examined self-reported craving in response to trauma and alcohol cues, no studies have reported on alcohol-related physiological responding in response to trauma cues i...

journal_title：Experimental and clinical psychopharmacology

authors： Coffey SF,Schumacher JA,Stasiewicz PR,Henslee AM,Baillie LE,Landy N

更新日期：2010-08-01 00:00:00

abstract：:The authors tested the hypothesis that the effects of nicotine on affect are moderated by the presence or absence of emotionally positive and negative stimuli and by attentional choice to avoid attending to emotionally negative stimuli. Thirty-two habitual smokers were assigned to tasks allowing attentional freedom to...

journal_title：Experimental and clinical psychopharmacology

authors： Gilbert DG,Riise H,Dillon A,Huber J,Rabinovich NE,Sugai C

更新日期：2008-02-01 00:00:00

abstract：:Polychlorinated biphenyls (PCBs) are ubiquitous environmental toxicants known to adversely impact human health. Ortho-substituted PCBs affect the nervous system, including the brain dopaminergic system. The reinforcing effects of psychostimulants are typically modulated via the dopaminergic system, so this study used ...

journal_title：Experimental and clinical psychopharmacology

authors： Miller MM,Meyer AE,Sprowles JL,Sable HJ

更新日期：2017-04-01 00:00:00

abstract：:Drug abuse and impulsive choice are related in humans. In female rats, impulsive choice predicted the rate of acquisition of IV cocaine self-administration. The objectives of the present experiments were to: (a) compare impulsive choice in males and females, (b) extend previous research on impulsive choice and acquisi...

journal_title：Experimental and clinical psychopharmacology

authors： Perry JL,Nelson SE,Carroll ME

更新日期：2008-04-01 00:00:00

abstract：:Relative to intravenous drug self-administration, locomotor activity is easier to measure with high throughput, particularly in mice. Therefore its potential to predict differences in self-administration between genotypes (e.g., targeted mutations, recombinant inbred strains) is appealing, but such predictive value is...

journal_title：Experimental and clinical psychopharmacology

authors： Thomsen M,Caine SB

更新日期：2011-10-01 00:00:00

abstract：:Using data from 4 smoking cessation trials conducted from 1988 to 2000, the authors investigated whether men are more successful than women in quitting smoking. Odds ratios indicated that the abstinence rates were not significantly different for men and women. Thus, there may be little value to diverting research fund...

journal_title：Experimental and clinical psychopharmacology

authors： Killen JD,Fortmann SP,Varady A,Kraemer HC

更新日期：2002-08-01 00:00:00

abstract：:Increased discounting (devaluing) of delayed rewards is associated with nearly all types of substance use disorders (SUDs) and is also present in individuals with family histories of SUDs. Early life adversity (ELA) likely contributes to these findings as it is common in both individuals with SUDs and their children a...

journal_title：Experimental and clinical psychopharmacology

authors： Acheson A,Vincent AS,Cohoon A,Lovallo WR

更新日期：2019-04-01 00:00:00

abstract：:Although the important roles of postquit affect and withdrawal symptoms in the process of smoking cessation have been well established, little is known about the relations between prequit affective trajectories and cessation outcome on the target quit date (TQD). This study examined whether a 16-week course of fluoxet...

journal_title：Experimental and clinical psychopharmacology

authors： Minami H,Kahler CW,Bloom EL,Prince MA,Abrantes AM,Strong DR,Niaura R,Miller IW,Palm Reed KM,Price LH,Brown RA

更新日期：2014-10-01 00:00:00

abstract：:In an elegant series of experiments, F. Leri and J. Stewart (2002) report that exposure to heroin increases subsequent reinstatement responding if the animal has access to the drug lever during the lapse and if responding on the lever results in the presentation of conditioned cues. It is interesting that exposure to ...

journal_title：Experimental and clinical psychopharmacology

authors： Goeders NE

更新日期：2002-11-01 00:00:00

abstract：:Smokers are highly reactive to smoking-related cues that are directly linked, or most proximal, to actual smoking behavior (e.g., lit cigarettes). However, over the course of smoking, proximal cues may not be the only stimuli to become strongly associated with smoking. Distal cues, such as the environments in which sm...

journal_title：Experimental and clinical psychopharmacology

authors： Conklin CA,Robin N,Perkins KA,Salkeld RP,McClernon FJ

更新日期：2008-06-01 00:00:00

abstract：:The social environment plays a critical role in determining the likelihood that an individual will use drugs or will develop a drug use disorder. Recent evidence obtained from preclinical studies reveals that proximal social factors (i.e., those factors that are immediately present at the time of drug exposure) exert ...

journal_title：Experimental and clinical psychopharmacology

authors： Strickland JC,Smith MA

更新日期：2014-02-01 00:00:00

abstract：:The consumption of caffeine has become a growing concern, partially because of the withdrawal properties of the drug. The current study examined personality correlates of caffeine consumption and dependence in 60 university students. Self-report and behavioral measures of sensation seeking, impulsivity, and risk takin...

journal_title：Experimental and clinical psychopharmacology

authors： Jones HA,Lejuez CW

更新日期：2005-08-01 00:00:00

abstract：:Social learning theory considers self-efficacy as a causal factor in behavior change. However, in line with behavioral theory, recent clinical research suggests self-efficacy ratings may reflect, rather than cause, behavior change. To test these two disparate views, self-efficacy was related to actual smoking abstinen...

journal_title：Experimental and clinical psychopharmacology

authors： Perkins KA,Parzynski C,Mercincavage M,Conklin CA,Fonte CA

更新日期：2012-02-01 00:00:00

abstract：:Despite considerable health risks due to lower levels of estrogen production and the compounding antiestrogenic effects of nicotine, postmenopausal females continue to smoke. These females face significant barriers to cessation, including negative affect, weight concerns, and menopausal symptom severity. The current p...

journal_title：Experimental and clinical psychopharmacology

authors： Peltier MR,Roys MR,Waters AF,Vinci C,Waldo KM,Stewart SA,Toups RC,Jones L,Copeland AL

更新日期：2018-04-01 00:00:00

abstract：:The "social lubrication" function of alcohol during interpersonal interactions is well documented. However, less is known about the effects of alcohol consumption on group-level behavior. Empirical findings from social psychological literature suggest that individuals tend to favor those who are considered as members ...

journal_title：Experimental and clinical psychopharmacology

authors： Zhou J,Heim D,Monk R,Levy A,Pollard P

更新日期：2018-06-01 00:00:00

abstract：:Nonpharmacological cues associated with drug intake may influence subjective and reinforcing effects of those drugs. Social drinkers (N = 80) participated in 2 sessions in which they rated and then consumed ad lib their preferred beer (with participants blind to brand). Visual and olfactory stimuli were obscured durin...

journal_title：Experimental and clinical psychopharmacology

authors： Perkins KA,Ciccocioppo M,Jacobs L,Doyle T,Caggiula A

更新日期：2003-11-01 00:00:00

abstract：:Rats were exposed to a diet containing 100 ppm cadmium chloride or a control diet. At 52 days of exposure, rats were trained to discriminate between saline and 5 mg/kg cocaine injections. After acquisition training, successive substitution tests were conducted using cocaine, the indirect dopamine agonist d-amphetamine...

journal_title：Experimental and clinical psychopharmacology

authors： Nation JR,Miller DK

更新日期：1999-05-01 00:00:00

abstract：:The relationship between nicotine abstinence and panic onset is still not well understood and the role of catastrophic misinterpretation, as possible moderator or mediator of this relationship, is unknown. We tested whether nicotine abstinence influences the response to a CO₂ panic challenge and whether catastrophic m...

journal_title：Experimental and clinical psychopharmacology

authors： Cosci F,Ibrahim HM,Nannini A,Schruers K

更新日期：2015-12-01 00:00:00

abstract：:While smokers are known to find smoking-related stimuli motivationally salient, the extent to which former smokers do so is largely unknown. In this study, we collected event-related potential (ERP) data from former and never smokers and compared them to a sample of current smokers interested in quitting who completed...

journal_title：Experimental and clinical psychopharmacology

authors： Robinson JD,Versace F,Engelmann JM,Cui Y,Slapin A,Oum R,Cinciripini PM

更新日期：2015-02-01 00:00:00

abstract：:The present, subjective value of a reinforcer typically decreases as a function of the delay to its receipt, a phenomenon termed delay discounting. Delay discounting, which is assumed to reflect impulsivity, is hypothesized to play an important role in drug abuse. The present study examined delay discounting of cocain...

journal_title：Experimental and clinical psychopharmacology

authors： Woolverton WL,Myerson J,Green L

更新日期：2007-06-01 00:00:00

abstract：:This study examined the relation of the Five-Factor Model (FFM) of personality to symptoms of alcohol and marijuana abuse before and after controlling for symptoms of antisocial personality disorder (APD) and internalizing psychopathology. The 481 participants completed a well-validated measure of the FFM and a struct...

journal_title：Experimental and clinical psychopharmacology

authors： Flory K,Lynam D,Milich R,Leukefeld C,Clayton R

更新日期：2002-11-01 00:00:00

abstract：:Oxytocin has been shown to decrease cocaine taking and seeking in male rats, suggesting potential treatment efficacy for drug addiction. In the present study, we extended these findings to the assessment of cocaine seeking and taking in female rats. Further, we made direct comparisons of oxytocin's impact on cocaine i...

journal_title：Experimental and clinical psychopharmacology

authors： Leong KC,Zhou L,Ghee SM,See RE,Reichel CM

更新日期：2016-02-01 00:00:00

abstract：:Nicotine addiction continues to be the main cause of preventable death in developed countries. Women and teen girls appear to be more vulnerable on certain aspects of nicotine addiction compared with men and boys. While the mechanism of gender differences in nicotine addiction is not yet clear, evidence suggests that ...

journal_title：Experimental and clinical psychopharmacology

authors： Lynch WJ,Sofuoglu M

更新日期：2010-12-01 00:00:00

abstract：:Previous research has shown that social drinkers continue to show attentional bias toward alcohol-related stimuli even after consuming a moderate dose of alcohol. In contrast, little is known about how alcohol acutely affects attentional bias in groups at risk to develop alcohol-related problems, such as adults with a...

journal_title：Experimental and clinical psychopharmacology

authors： Roberts W,Fillmore MT,Milich R

更新日期：2012-04-01 00:00:00

abstract：:Prescription stimulant misuse (PSM) is common in young adult college students, at over 10% in the past year, and it is associated with other substance use and risk behaviors. Research focused on the real-time drivers of PSM is absent, impeding prevention and intervention. This research aimed to fill that gap by examin...

journal_title：Experimental and clinical psychopharmacology

authors： Schepis TS,Buckner JD,Klare DL,Wade LR,Benedetto N

更新日期：2020-05-28 00:00:00

abstract：:This report describes a novel procedure for computer-controlled drug-dose determination for IV drug self-administration studies. By modifying the duration of each infusion of a single concentration of a drug solution, five or more unit doses (mg/kg/inj) can be dispensed from the same syringe. The advantages of this pr...

journal_title：Experimental and clinical psychopharmacology

authors： Fivel PA

更新日期：2011-04-01 00:00:00

abstract：:There are important individual differences in acute subjective responses to alcohol, which have often been assessed using self-report measures. There is also evidence of meaningful between-persons variation in alcohol's disinhibiting effects on behavior, such that some individuals become more impaired on tasks of inhi...

journal_title：Experimental and clinical psychopharmacology

authors： Quinn PD,Fromme K

更新日期：2016-04-01 00:00:00

abstract：:Lapses within the first 2 weeks of a smoking cessation attempt are strongly associated with a return to regular smoking (S. L. Kenford et al., 1994). Unfortunately, little is known about how to prevent an initial lapse from progressing to a full relapse, and presently there are no validated lapse-responsive therapeuti...

journal_title：Experimental and clinical psychopharmacology

authors： Juliano LM,Houtsmuller EJ,Stitzer ML

更新日期：2006-11-01 00:00:00

abstract：:Dependence on and abuse of prescription opioid drugs is now a major health problem, with initiation of prescription opioid abuse exceeding cocaine in young people. Coincident with the emergence of abuse and dependence on prescription opioids, there has been an increased emphasis on the treatment of pain. Pain is now t...

journal_title：Experimental and clinical psychopharmacology

authors： Mendelson J,Flower K,Pletcher MJ,Galloway GP

更新日期：2008-10-01 00:00:00

abstract：:The accurate assessment of nicotine withdrawal is important theoretically and clinically. A 28-item scale, the Wisconsin Smoking Withdrawal Scale, was developed that contains 7 reliable subscales tapping the major symptom elements of the nicotine withdrawal syndrome. Coefficients alpha for the subscales range from .75...

journal_title：Experimental and clinical psychopharmacology

authors： Welsch SK,Smith SS,Wetter DW,Jorenby DE,Fiore MC,Baker TB

更新日期：1999-11-01 00:00:00