B Chromosomes in the Drosophila Genus.

abstract：:Single-cell RNA sequencing (scRNA-seq) has recently brought new insight into cell differentiation processes and functional variation in cell subtypes from homogeneous cell populations. A lack of prior knowledge makes unsupervised machine learning methods, such as clustering, suitable for analyzing scRNA-seq . However,...

journal_title：Genes

authors： Zhu X,Li HD,Xu Y,Guo L,Wu FX,Duan G,Wang J

更新日期：2019-01-29 00:00:00

abstract：:The transcription factor PAX6 is essential in ocular development in vertebrates, being considered the master regulator of the eye. During eye development, it is essential for the correct patterning and formation of the multi-layered optic cup and it is involved in the developing lens and corneal epithelium. In adultho...

journal_title：Genes

authors： Lima Cunha D,Arno G,Corton M,Moosajee M

更新日期：2019-12-17 00:00:00

abstract：:MYO6 is known as a genetic cause of autosomal dominant and autosomal recessive inherited hearing loss. In this study, to clarify the frequency and clinical characteristics of hearing loss caused by MYO6 gene mutations, a large-scale genetic analysis of Japanese patients with hearing loss was performed. By means of mas...

journal_title：Genes

authors： Oka SI,Day TF,Nishio SY,Moteki H,Miyagawa M,Morita S,Izumi S,Ikezono T,Abe S,Nakayama J,Hyogo M,Okamoto N,Uehara N,Oshikawa C,Kitajiri SI,Usami SI

更新日期：2020-03-04 00:00:00

abstract：:Lower levels of physical activity (PA) have been associated with increased risk of cardiovascular disease. Worldwide, there is a shift towards a lifestyle with less PA, posing a serious threat to public health. One of the suggested mechanisms behind the association between PA and disease development is through systemi...

journal_title：Genes

authors： Prins FM,Said MA,van de Vegte YJ,Verweij N,Groot HE,van der Harst P

更新日期：2019-11-07 00:00:00

abstract：:Cytokinin oxidase/dehydrogenases (CKXs) play a critical role in the irreversible degradation of cytokinins, thereby regulating plant growth and development. Brassica napus is one of the most widely cultivated oilseed crops worldwide. With the completion of whole-genome sequencing of B. napus, genome-wide identificatio...

journal_title：Genes

authors： Liu P,Zhang C,Ma JQ,Zhang LY,Yang B,Tang XY,Huang L,Zhou XT,Lu K,Li JN

更新日期：2018-03-16 00:00:00

abstract：:Inositol trisphosphate receptor (IP3R) mediated Ca+2 signaling is essential in determining the cell fate by regulating numerous cellular processes, including cell division and cell death. Despite extensive studies about the characterization of IP3R in cancer, the underlying molecular mechanism initiating the cell prol...

journal_title：Genes

authors： Ismatullah H,Jabeen I,Saeed MT

更新日期：2020-12-29 00:00:00

abstract：:The integration of phenotypes and genotypes is at an unprecedented level and offers new opportunities to establish deep phenotypes. There are a number of challenges to overcome, specifically, accelerated growth of data, data silos, incompleteness, inaccuracies, and heterogeneity within and across data sources. This pe...

journal_title：Genes

authors： Frey LJ

更新日期：2018-12-28 00:00:00

abstract：:The woody Sonchus alliance consists primarily of woody species of the genus Sonchus (subgenus Dendrosonchus; family Asteraceae). Most members of the alliance are endemic to the oceanic archipelagos in the phytogeographic region of Macaronesia. They display extensive morphological, ecological, and anatomical diversity,...

journal_title：Genes

authors： Cho MS,Yang JY,Yang TJ,Kim SC

更新日期：2019-03-14 00:00:00

abstract：:Asian rice (Oryza sativa) and African rice (Oryza glaberrima) are separately domesticated from their wild ancestors Oryza rufipogon and Oryza barthii, which are very sensitive to daylength. In the process of domestication, some traits that are favorable for the natural survival of wild rice such as seed dormancy and s...

journal_title：Genes

authors： Liu H,Li Q,Xing Y

更新日期：2018-10-10 00:00:00

abstract：:The multiple organellar RNA editing factors (MORF) gene family plays a key role in organelle RNA editing in flowering plants. MORF genes expressions are also affected by abiotic stress. Although seven OsMORF genes have been identified in rice, few reports have been published on their expression patterns in different t...

journal_title：Genes

authors： Zhang Q,Shen L,Ren D,Hu J,Chen G,Zhu L,Gao Z,Zhang G,Guo L,Zeng D,Qian Q

更新日期：2019-09-10 00:00:00

abstract：:We studied and compared the nucleolar expression or nucleoli from specific bivalents in spermatocytes of the standard Mus musculus domesticus 2n=40, of Robertsonian (Rb) homozygotes 2n = 24 and heterozygotes 2n = 32. We analyzed 200 nuclear microspreads of each specific nucleolar chromosome and spermatocyte karyotype,...

journal_title：Genes

authors： López-Moncada F,Tapia D,Zuñiga N,Ayarza E,López-Fenner J,Redi CA,Berríos S

更新日期：2019-02-06 00:00:00

abstract：:The development of the udder and the milk yield are closely related to the number and vitality of mammary epithelial cells. Many previous studies have proved that non-coding RNAs (ncRNAs) are widely involved in mammary gland development and the physiological activities of lactation. Our laboratory previous sequencing ...

journal_title：Genes

authors： Zhang M,Ma L,Liu Y,He Y,Li G,An X,Cao B

更新日期：2020-06-28 00:00:00

abstract：:Mobile DNA elements play a significant evolutionary role by promoting genome plasticity. Insertion sequences are the smallest prokaryotic transposable elements. They are highly diverse elements, and the ability to accurately identify, annotate, and infer the full genomic impact of insertion sequences is lacking. Halan...

journal_title：Genes

authors： Sadler M,R Mormile M,L Frank R

更新日期：2020-04-29 00:00:00

abstract：:Cancer stem cells (CSCs), having both self-renewal and tumorigenic capacity, utilize an energy metabolism system different from that of non-CSCs. Lipid droplets (LDs) are organelles that store neutral lipids, including triacylglycerol. Previous studies demonstrated that LDs are formed and store lipids as an energy sou...

journal_title：Genes

authors： Kuramoto K,Yamamoto M,Suzuki S,Togashi K,Sanomachi T,Kitanaka C,Okada M

更新日期：2021-01-14 00:00:00

abstract：:Silver-Russell syndrome (SRS) is a rare growth-related genetic disorder that is mainly associated with prenatal and postnatal growth retardation. Molecular causes are not clear in all cases, the most common ones being loss of methylation on chromosome 11p15 (≈50%) and maternal uniparental disomy for chromosome 7 (upd(...

journal_title：Genes

authors： Vado Y,Pereda A,Llano-Rivas I,Gorria-Redondo N,Díez I,Perez de Nanclares G

更新日期：2020-12-05 00:00:00

abstract：:DNA methyltransferases (DNMTs) play an essential role in DNA methylation and transcriptional regulation in the genome. DNMTs, along with other poorly studied elements, modulate the dynamic DNA methylation patterns of embryonic and adult cells. We summarize the current knowledge on the molecular mechanism of DNMTs' fun...

journal_title：Genes

authors： Loaeza-Loaeza J,Beltran AS,Hernández-Sotelo D

更新日期：2020-11-12 00:00:00

abstract：:Novel coat colour phenotypes often emerge during domestication, and there is strong evidence of genetic selection for the two main genes that control base coat colour in horses-ASIP and MC1R. These genes direct the type of pigment produced, red pheomelanin (MC1R) or black eumelanin (ASIP), as well as the relative conc...

journal_title：Genes

authors： Corbin LJ,Pope J,Sanson J,Antczak DF,Miller D,Sadeghi R,Brooks SA

更新日期：2020-05-30 00:00:00

abstract：:We set out to assess the NIH/3T3 cell proliferation activity of Arabidopsis oil body-expressed recombinant oleosin-hEGF-hEGF protein. Normally, human epidermal growth factor (hEGF) is purified through complex process, however, oleosin fusion technology provides an inexpensive and scalable platform for its purification...

journal_title：Genes

authors： Qiang W,Gao T,Lan X,Guo J,Noman M,Li Y,Guo Y,Kong J,Li H,Du L,Yang J

更新日期：2020-08-19 00:00:00

abstract：:Amazonian puffing snakes (Spilotes; Colubridae) are snakes widely distributed in the Neotropical region. However, chromosomal data are scarce in this group and, when available, are only limited to karyotype description using conventional staining. In this paper, we focused on the process of karyotype evolution and tre...

journal_title：Genes

authors： Viana PF,Ezaz T,de Bello Cioffi M,Jackson Almeida B,Feldberg E

更新日期：2019-04-09 00:00:00

abstract：:Olfaction, which is mediated by olfactory receptor (OR) genes, is essential in the daily life of fish, especially in foraging. However, Chinese perch (Siniperca chuatsi) is believed to prey with reliance on vision and lateral sensation, but not on olfaction. Therefore, understanding the evolutionary dynamics of the Ch...

journal_title：Genes

authors： Lv LY,Liang XF,He S

更新日期：2019-02-25 00:00:00

abstract：:Shiga toxin-producing Escherichia coli (STEC) are foodborne pathogens associated with outbreaks and hemolytic-uremic syndrome. Cattle and meat foods are the main reservoir and infection source, respectively. Pathogenicity islands (PAIs) play an important role in STEC pathogenicity, and non-locus of the enterocyte effa...

journal_title：Genes

authors： Soledad-Cadona J,Bustamante AV,González J,Mariel-Sanso A

更新日期：2018-02-10 00:00:00

abstract：:The Zn(II)₂Cys₆ zinc cluster gene family is a subclass of zinc-finger proteins, which are transcriptional regulators involved in a wide variety of biological processes in fungi. We performed genome-wide identification and characterization of Zn(II)₂Cys₆ zinc-cluster gene (C6 zinc gene) family in Tolypocladiumguangdong...

journal_title：Genes

authors： Zhang C,Huang H,Deng W,Li T

更新日期：2019-02-26 00:00:00

abstract：:DNA methylation patterns have been shown to change throughout the normal aging process. Several studies have found epigenetic aging markers using age predictors, but these studies only focused on blood-specific or tissue-common methylation patterns. Here, we constructed nine tissue-specific age prediction models using...

journal_title：Genes

authors： Choi H,Joe S,Nam H

更新日期：2019-11-04 00:00:00

abstract：:Staphylococcus aureus is a major human pathogen and an important cause of livestock infections. More than 20 staphylococcal enterotoxins with emetic activity can be produced by specific strains responsible for staphylococcal food poisoning, one of the most common food-borne diseases. Whole genome sequencing provides a...

journal_title：Genes

authors： Macori G,Bellio A,Bianchi DM,Chiesa F,Gallina S,Romano A,Zuccon F,Cabrera-Rubio R,Cauquil A,Merda D,Auvray F,Decastelli L

更新日期：2019-12-27 00:00:00

abstract：:This review looks back at five decades of research into genetic susceptibility to colorectal cancer (CRC) and the insights these studies have provided. Initial evidence of a genetic basis of CRC stems from epidemiological studies in the 1950s and is further provided by the existence of multiple dominant predisposition...

journal_title：Genes

authors： Whiffin N,Houlston RS

更新日期：2014-03-27 00:00:00

abstract：:Spiders often produce multiple types of silk, each with unique properties suiting them to certain tasks and biological functions. Orb-weaver spiders can generate more than six types of silk fibroins, with pyriform silk used to form attachment discs, adhering silk to other surfaces and substances. The unique higher-ord...

journal_title：Genes

authors： Wang K,Wen R,Jia Q,Liu X,Xiao J,Meng Q

更新日期：2019-06-03 00:00:00

abstract：:The availability of the genome sequence of the unisexual (male-female) Caenorhabditis nigoni offers an opportunity to compare its non-coding features with the related hermaphroditic species Caenorhabditis briggsae; to understand the evolutionary dynamics of their tandem repeat sequences (satellites), as a result of ev...

journal_title：Genes

authors： Subirana JA,Messeguer X

更新日期：2017-11-28 00:00:00

abstract：:Neurofibromatosis type 1 (NF1) is a cancer predisposition syndrome that results from dominant loss-of-function mutations mainly in the NF1 gene. Large rearrangements are present in 5-10% of affected patients, generally encompass NF1 neighboring genes, and are correlated with a more severe NF1 phenotype. Evident genoty...

journal_title：Genes

authors： Brussa Reis L,Turchetto-Zolet AC,Fonini M,Ashton-Prolla P,Rosset C

更新日期：2019-10-24 00:00:00

abstract：:Intercellular karyotypic variability has been a focus of genetic research for more than 50 years. It has been repeatedly shown that chromosome heterogeneity manifesting as chromosomal mosaicism is associated with a variety of human diseases. Due to the ability of changing dynamically throughout the ontogeny, chromosom...

journal_title：Genes

authors： Iourov IY,Vorsanova SG,Yurov YB,Kutsev SI

更新日期：2019-05-19 00:00:00

abstract：:Chlorella is a popular microalga with robust physiological and biochemical characteristics, which can be cultured under various conditions. The exploration of the small RNA content of Chlorella could improve strategies for the enhancement of metabolite production from this microalga. In this study, stress was introduc...

journal_title：Genes

authors： Azaman SNA,Satharasinghe DA,Tan SW,Nagao N,Yusoff FM,Yeap SK

更新日期：2020-09-25 00:00:00