B Chromosomes in the Drosophila Genus.

Abstract:

:Our current knowledge of B chromosome biology has been augmented by an increase in the number and diversity of species observed to carry B chromosomes as well as the use of next-generation sequencing for B chromosome genomic analysis. Within the genus Drosophila, B chromosomes have been observed in a handful of species, but recently they were discovered in a single laboratory stock of Drosophila melanogaster. In this paper, we review the B chromosomes that have been identified within the Drosophila genus and pay special attention to those recently found in D. melanogaster. These newly-discovered B chromosomes have centromeres, telomeres, and a number of simple satellite repeats. They also appear to be entirely heterochromatic since next-generation sequencing of isolated B chromosomes did not detect sequences associated with known genic regions. We also summarize what effects the B chromosomes have been found to have on the A chromosomes. Lastly, we highlight some of the outstanding questions regarding B chromosome biology and discuss how studying B chromosomes in Drosophila melanogaster, which is a versatile model system with a wealth of genetic and genomic tools, may advance our understanding of the B chromosome's unique biology.

journal_name

Genes (Basel)

journal_title

Genes

authors

Hanlon SL,Hawley RS

doi

10.3390/genes9100470

subject

Has Abstract

pub_date

2018-09-27 00:00:00

issue

10

issn

2073-4425

pii

genes9100470

journal_volume

9

pub_type

杂志文章,评审

相关文献

Genes文献大全
  • Clinical Characteristics and In Vitro Analysis of MYO6 Variants Causing Late-Onset Progressive Hearing Loss.

    abstract::MYO6 is known as a genetic cause of autosomal dominant and autosomal recessive inherited hearing loss. In this study, to clarify the frequency and clinical characteristics of hearing loss caused by MYO6 gene mutations, a large-scale genetic analysis of Japanese patients with hearing loss was performed. By means of mas...

    journal_title:Genes

    pub_type: 杂志文章

    doi:10.3390/genes11030273

    authors: Oka SI,Day TF,Nishio SY,Moteki H,Miyagawa M,Morita S,Izumi S,Ikezono T,Abe S,Nakayama J,Hyogo M,Okamoto N,Uehara N,Oshikawa C,Kitajiri SI,Usami SI

    更新日期:2020-03-04 00:00:00

  • From Chromosomes to Genome: Insights into the Evolutionary Relationships and Biogeography of Old World Knifefishes (Notopteridae; Osteoglossiformes).

    abstract::In addition to its wide geographical distribution, osteoglossiform fishes represent one of the most ancient freshwater teleost lineages; making it an important group for systematic and evolutionary studies. These fishes had a Gondwanan origin and their past distribution may have contributed to the diversity present in...

    journal_title:Genes

    pub_type: 杂志文章

    doi:10.3390/genes9060306

    authors: Barby FF,Ráb P,Lavoué S,Ezaz T,Bertollo LAC,Kilian A,Maruyama SR,Aguiar de Oliveira E,Artoni RF,Santos MH,Ilesanmi Jegede O,Hatanaka T,Tanomtong A,Liehr T,Cioffi MB

    更新日期:2018-06-19 00:00:00

  • Genome Sequencing and Assembly by Long Reads in Plants.

    abstract::Plant genomes generated by Sanger and Next Generation Sequencing (NGS) have provided insight into species diversity and evolution. However, Sanger sequencing is limited in its applications due to high cost, labor intensity, and low throughput, while NGS reads are too short to resolve abundant repeats and polyploidy, l...

    journal_title:Genes

    pub_type: 杂志文章,评审

    doi:10.3390/genes9010006

    authors: Li C,Lin F,An D,Wang W,Huang R

    更新日期:2017-12-28 00:00:00

  • A 24-Month Follow-Up Study of the Effect of Intra-Articular Injection of Autologous Microfragmented Fat Tissue on Proteoglycan Synthesis in Patients with Knee Osteoarthritis.

    abstract::Osteoarthritis (OA) is a widely prevalent disease worldwide, and with an increasingly ageing society, it has become a challenge for the field of regenerative medicine. OA is a disease process involving multiple joint tissues, including those not visible on radiography, and is a complex disease process with multiple ph...

    journal_title:Genes

    pub_type: 杂志文章

    doi:10.3390/genes10121051

    authors: Borić I,Hudetz D,Rod E,Jeleč Ž,Vrdoljak T,Skelin A,Polašek O,Plečko M,Trbojević-Akmačić I,Lauc G,Primorac D

    更新日期:2019-12-17 00:00:00

  • Genetic Association between Amyotrophic Lateral Sclerosis and Cancer.

    abstract::Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease. An ALS drug, Riluzole, has been shown to induce two different anticancer effects on hepatocellular carcinoma (HCC). In light of this finding, we explore the relationship between ALS and cancer, especially for HCC, from the molecular biological v...

    journal_title:Genes

    pub_type: 杂志文章

    doi:10.3390/genes8100243

    authors: Taguchi YH,Wang H

    更新日期:2017-09-27 00:00:00

  • Impact, Characterization, and Rescue of Pre-mRNA Splicing Mutations in Lysosomal Storage Disorders.

    abstract::Lysosomal storage disorders (LSDs) represent a group of more than 50 severe metabolic diseases caused by the deficiency of specific lysosomal hydrolases, activators, carriers, or lysosomal integral membrane proteins, leading to the abnormal accumulation of substrates within the lysosomes. Numerous mutations have been ...

    journal_title:Genes

    pub_type: 杂志文章,评审

    doi:10.3390/genes9020073

    authors: Dardis A,Buratti E

    更新日期:2018-02-06 00:00:00

  • Ectopic Expression of AhGLK1b (GOLDEN2-like Transcription Factor) in Arabidopsis Confers Dual Resistance to Fungal and Bacterial Pathogens.

    abstract::GOLDEN2-LIKE (GLK) is a member of the myeloblastosis (MYB) family transcription factor and it plays an important role in the regulation of plastid development and stress tolerance. In this study, a gene named AhGLK1b was identified from a cultivated peanut showing down-regulation in response to low calcium with a comp...

    journal_title:Genes

    pub_type: 杂志文章

    doi:10.3390/genes11030343

    authors: Ali N,Chen H,Zhang C,Khan SA,Gandeka M,Xie D,Zhuang W

    更新日期:2020-03-24 00:00:00

  • Germline-Specific Repetitive Elements in Programmatically Eliminated Chromosomes of the Sea Lamprey (Petromyzon marinus).

    abstract::The sea lamprey (Petromyzon marinus) is one of few vertebrate species known to reproducibly eliminate large fractions of its genome during normal embryonic development. This germline-specific DNA is lost in the form of large fragments, including entire chromosomes, and available evidence suggests that DNA elimination ...

    journal_title:Genes

    pub_type: 杂志文章

    doi:10.3390/genes10100832

    authors: Timoshevskiy VA,Timoshevskaya NY,Smith JJ

    更新日期:2019-10-22 00:00:00

  • Genetic Architecture Underpinning Yield Components and Seed Mineral-Nutrients in Sesame.

    abstract::Genetic dissection of yield components and seed mineral-nutrient is crucial for understanding plant physiological and biochemical processes and alleviate nutrient malnutrition. Sesame (Sesamum indicum L.) is an orphan crop that harbors rich allelic repertoire for seed mineral-nutrients. Here, we harness this wide dive...

    journal_title:Genes

    pub_type: 杂志文章

    doi:10.3390/genes11101221

    authors: Teboul N,Gadri Y,Berkovich Z,Reifen R,Peleg Z

    更新日期:2020-10-18 00:00:00

  • Genetic Basis of Maize Resistance to Multiple Insect Pests: Integrated Genome-Wide Comparative Mapping and Candidate Gene Prioritization.

    abstract::Several species of herbivores feed on maize in field and storage setups, making the development of multiple insect resistance a critical breeding target. In this study, an association mapping panel of 341 tropical maize lines was evaluated in three field environments for resistance to fall armyworm (FAW), whilst bulke...

    journal_title:Genes

    pub_type: 杂志文章

    doi:10.3390/genes11060689

    authors: Badji A,Kwemoi DB,Machida L,Okii D,Mwila N,Agbahoungba S,Kumi F,Ibanda A,Bararyenya A,Solemanegy M,Odong T,Wasswa P,Otim M,Asea G,Ochwo-Ssemakula M,Talwana H,Kyamanywa S,Rubaihayo P

    更新日期:2020-06-24 00:00:00

  • X-Linked Duchenne-Type Muscular Dystrophy in Jack Russell Terrier Associated with a Partial Deletion of the Canine DMD Gene.

    abstract::A 9-month old male Jack Russell Terrier started showing paraparesis of the hindlimbs after a walk. Hospitalized, the dog went into cardiac arrest, and later died. Necroscopic examination revealed a severe thickness of the diaphragm, esophagus, and base of the tongue, leading to the diagnosis of muscular dystrophy. The...

    journal_title:Genes

    pub_type:

    doi:10.3390/genes11101175

    authors: Brunetti B,Muscatello LV,Letko A,Papa V,Cenacchi G,Grillini M,Murgiano L,Jagannathan V,Drögemüller C

    更新日期:2020-10-08 00:00:00

  • Novel Variant in PLAG1 in a Familial Case with Silver-Russell Syndrome Suspicion.

    abstract::Silver-Russell syndrome (SRS) is a rare growth-related genetic disorder that is mainly associated with prenatal and postnatal growth retardation. Molecular causes are not clear in all cases, the most common ones being loss of methylation on chromosome 11p15 (≈50%) and maternal uniparental disomy for chromosome 7 (upd(...

    journal_title:Genes

    pub_type:

    doi:10.3390/genes11121461

    authors: Vado Y,Pereda A,Llano-Rivas I,Gorria-Redondo N,Díez I,Perez de Nanclares G

    更新日期:2020-12-05 00:00:00

  • RNA Sequencing Analysis of Chicken Cecum Tissues Following Eimeria tenella Infection in Vivo.

    abstract::Eimeria tenella (E. tenella) is one of the most frequent and pathogenic species of protozoan parasites of the genus Eimeria that exclusively occupies the cecum, exerting a high economic impact on the poultry industry. To investigate differentially expressed genes (DEGs) in the cecal tissue of Jinghai yellow chickens i...

    journal_title:Genes

    pub_type: 杂志文章

    doi:10.3390/genes10060420

    authors: Wang X,Zou W,Yu H,Lin Y,Dai G,Zhang T,Zhang G,Xie K,Wang J,Shi H

    更新日期:2019-05-31 00:00:00

  • Horizontally Acquired Homologs of Xenogeneic Silencers: Modulators of Gene Expression Encoded by Plasmids, Phages and Genomic Islands.

    abstract::Acquisition of mobile elements by horizontal gene transfer can play a major role in bacterial adaptation and genome evolution by providing traits that contribute to bacterial fitness. However, gaining foreign DNA can also impose significant fitness costs to the host bacteria and can even produce detrimental effects. T...

    journal_title:Genes

    pub_type: 杂志文章,评审

    doi:10.3390/genes11020142

    authors: Piña-Iturbe A,Suazo ID,Hoppe-Elsholz G,Ulloa-Allendes D,González PA,Kalergis AM,Bueno SM

    更新日期:2020-01-29 00:00:00

  • Identification of a Missense Variant in MFSD12 Involved in Dilution of Phaeomelanin Leading to White or Cream Coat Color in Dogs.

    abstract::White coat color in mammals has been selected several times during the domestication process. Numerous dog breeds are fixed for one form of white coat color that involves darkly pigmented skin. The genetic basis of this color, due to the absence of pigment in the hairs, was suggested to correspond to extreme dilution ...

    journal_title:Genes

    pub_type: 杂志文章

    doi:10.3390/genes10050386

    authors: Hédan B,Cadieu E,Botherel N,Dufaure de Citres C,Letko A,Rimbault M,Drögemüller C,Jagannathan V,Derrien T,Schmutz S,Leeb T,André C

    更新日期:2019-05-21 00:00:00

  • Novel Sequence Features of DNA Repair Genes/Proteins from Deinococcus Species Implicated in Protection from Oxidatively Generated Damage.

    abstract::Deinococcus species display a high degree of resistance to radiation and desiccation due to their ability to protect critical proteome from oxidatively generated damage; however, the underlying mechanisms are not understood. Comparative analysis of DNA repair proteins reported here has identified 22 conserved signatur...

    journal_title:Genes

    pub_type: 杂志文章

    doi:10.3390/genes9030149

    authors: Hassan FMN,Gupta RS

    更新日期:2018-03-08 00:00:00

  • Pulmonary Hypertension Remodels the Genomic Fabrics of Major Functional Pathways.

    abstract::Pulmonary hypertension (PH) is a serious disorder with high morbidity and mortality rate. We analyzed the right-ventricular systolic pressure (RVSP), right-ventricular hypertrophy (RVH), lung histology, and transcriptomes of six-week-old male rats with PH induced by (1) hypoxia (HO), (2) administration of monocrotalin...

    journal_title:Genes

    pub_type: 杂志文章

    doi:10.3390/genes11020126

    authors: Mathew R,Huang J,Iacobas S,Iacobas DA

    更新日期:2020-01-23 00:00:00

  • Biodegradation of Tetralin: Genomics, Gene Function and Regulation.

    abstract::Tetralin (1,2,3,4-tetrahydonaphthalene) is a recalcitrant compound that consists of an aromatic and an alicyclic ring. It is found in crude oils, produced industrially from naphthalene or anthracene, and widely used as an organic solvent. Its toxicity is due to the alteration of biological membranes by its hydrophobic...

    journal_title:Genes

    pub_type: 杂志文章,评审

    doi:10.3390/genes10050339

    authors: Floriano B,Santero E,Reyes-Ramírez F

    更新日期:2019-05-06 00:00:00

  • 46,XY,r(8)/45,XY,-8 Mosaicism as a Possible Mechanism of the Imprinted Birk-Barel Syndrome: A Case Study.

    abstract::Ring chromosome 8 (r(8)) is one of the least frequent ring chromosomes. Usually, maternal chromosome 8 forms a ring, which can be lost from cells due to mitotic instability. The 8q24 region contains the imprinted KCNK9 gene, which is expressed from the maternal allele. Heterozygous KCNK9 mutations are associated with ...

    journal_title:Genes

    pub_type: 杂志文章

    doi:10.3390/genes11121473

    authors: Kashevarova AA,Nikitina TV,Mikhailik LI,Belyaeva EO,Vasilyev SA,Lopatkina ME,Fedotov DA,Fonova EA,Zarubin AA,Sivtsev AA,Skryabin NA,Nazarenko LP,Lebedev IN

    更新日期:2020-12-09 00:00:00

  • The Genomic Makeup of Nine Horse Populations Sampled in the Netherlands.

    abstract::The spectrum of modern horse populations encompasses populations with a long history of development in isolation and relatively recently formed types. To increase our understanding of the evolutionary history and provide information on how to optimally conserve or improve these populations with varying development and...

    journal_title:Genes

    pub_type: 杂志文章

    doi:10.3390/genes10060480

    authors: Schurink A,Shrestha M,Eriksson S,Bosse M,Bovenhuis H,Back W,Johansson AM,Ducro BJ

    更新日期:2019-06-25 00:00:00

  • Viral Vector-Mediated Antisense Therapy for Genetic Diseases.

    abstract::RNA plays complex roles in normal health and disease and is becoming an important target for therapeutic intervention; accordingly, therapeutic strategies that modulate RNA function have gained great interest over the past decade. Antisense oligonucleotides (AOs) are perhaps the most promising strategy to modulate RNA...

    journal_title:Genes

    pub_type: 杂志文章,评审

    doi:10.3390/genes8020051

    authors: Imbert M,Dias-Florencio G,Goyenvalle A

    更新日期:2017-01-26 00:00:00

  • Shared and Species-Specific Patterns of Nascent Y Chromosome Evolution in Two Guppy Species.

    abstract::Sex chromosomes form once recombination is halted around the sex-determining locus between a homologous pair of chromosomes, resulting in a male-limited Y chromosome. We recently characterized the nascent sex chromosome system in the Trinidadian guppy (Poeciliareticulata). The guppy Y is one of the youngest animal sex...

    journal_title:Genes

    pub_type: 杂志文章

    doi:10.3390/genes9050238

    authors: Morris J,Darolti I,Bloch NI,Wright AE,Mank JE

    更新日期:2018-05-03 00:00:00

  • Exercise and High-Fat Diet in Obesity: Functional Genomics Perspectives of Two Energy Homeostasis Pillars.

    abstract::The heavy impact of obesity on both the population general health and the economy makes clarifying the underlying mechanisms, identifying pharmacological targets, and developing efficient therapies for obesity of high importance. The main struggle facing obesity research is that the underlying mechanistic pathways are...

    journal_title:Genes

    pub_type: 杂志文章,评审

    doi:10.3390/genes11080875

    authors: Ghanemi A,Melouane A,Yoshioka M,St-Amand J

    更新日期:2020-07-31 00:00:00

  • Comprehensive Transcriptomic Analysis Identifies ST8SIA1 as a Survival-Related Sialyltransferase Gene in Breast Cancer.

    abstract::Hypersialylation caused by the overexpression of sialyltransferases (STs) is a common feature in cancer that is associated with several characteristics of tumorigenesis. Thus, identifying cancer-associated STs is critical for cancer therapy. However, ST screening has been frequently conducted in cell line models. In t...

    journal_title:Genes

    pub_type: 杂志文章

    doi:10.3390/genes11121436

    authors: Kan JY,Moi SH,Hung WC,Hou MF,Chen FM,Shih SL,Shiau JP,Li CL,Chiang CP

    更新日期:2020-11-28 00:00:00

  • Computational Strategies for Scalable Genomics Analysis.

    abstract::The revolution in next-generation DNA sequencing technologies is leading to explosive data growth in genomics, posing a significant challenge to the computing infrastructure and software algorithms for genomics analysis. Various big data technologies have been explored to scale up/out current bioinformatics solutions ...

    journal_title:Genes

    pub_type: 杂志文章

    doi:10.3390/genes10121017

    authors: Shi L,Wang Z

    更新日期:2019-12-06 00:00:00

  • Detection of Microaneurysms in Fundus Images Based on an Attention Mechanism.

    abstract::Microaneurysms (MAs) are the earliest detectable diabetic retinopathy (DR) lesions. Thus, the ability to automatically detect MAs is critical for the early diagnosis of DR. However, achieving the accurate and reliable detection of MAs remains a significant challenge due to the size and complexity of retinal fundus ima...

    journal_title:Genes

    pub_type: 杂志文章

    doi:10.3390/genes10100817

    authors: Zhang L,Feng S,Duan G,Li Y,Liu G

    更新日期:2019-10-17 00:00:00

  • Specific LTR-Retrotransposons Show Copy Number Variations between Wild and Cultivated Sunflowers.

    abstract::The relationship between variation of the repetitive component of the genome and domestication in plant species is not fully understood. In previous work, variations in the abundance and proximity to genes of long terminal repeats (LTR)-retrotransposons of sunflower (Helianthus annuus L.) were investigated by Illumina...

    journal_title:Genes

    pub_type: 杂志文章

    doi:10.3390/genes9090433

    authors: Mascagni F,Vangelisti A,Giordani T,Cavallini A,Natali L

    更新日期:2018-08-29 00:00:00

  • Novel Insights into Antiviral Gene Regulation of Red Swamp Crayfish, Procambarus clarkii, Infected with White Spot Syndrome Virus.

    abstract::White spot syndrome virus (WSSV), one of the major pathogens of Procambarus clarkii, has caused severe disruption to the aquaculture industry of P. clarkii in China. To reveal the gene regulatory mechanisms underlying WSSV infection, a comparative transcriptome analysis was performed among WSSV-infected susceptible in...

    journal_title:Genes

    pub_type: 杂志文章

    doi:10.3390/genes8110320

    authors: Yi S,Li Y,Shi L,Zhang L

    更新日期:2017-11-10 00:00:00

  • Heat Stress Impairs the Physiological Responses and Regulates Genes Coding for Extracellular Exosomal Proteins in Rat.

    abstract::Heat stress (HS) is challenging in humans and animals as it is a complicated regulatory mechanism. This prompted us to characterize the physiological and molecular responses of a HS-animal model. In this study, a rat model system was developed by using three temperature treatments (40 ℃, 42 ℃, and 43 ℃) and sixteen bi...

    journal_title:Genes

    pub_type: 杂志文章

    doi:10.3390/genes11030306

    authors: Dou J,Khan A,Khan MZ,Mi S,Wang Y,Yu Y,Wang Y

    更新日期:2020-03-13 00:00:00

  • An Overview of Duplicated Gene Detection Methods: Why the Duplication Mechanism Has to Be Accounted for in Their Choice.

    abstract::Gene duplication is an important evolutionary mechanism allowing to provide new genetic material and thus opportunities to acquire new gene functions for an organism, with major implications such as speciation events. Various processes are known to allow a gene to be duplicated and different models explain how duplica...

    journal_title:Genes

    pub_type: 杂志文章,评审

    doi:10.3390/genes11091046

    authors: Lallemand T,Leduc M,Landès C,Rizzon C,Lerat E

    更新日期:2020-09-04 00:00:00