Haves and have nots must find a better way: The case for open scientific hardware.


:Many efforts are making science more open and accessible; they are mostly concentrated on issues that appear before and after experiments are performed: open access journals, open databases, and many other tools to increase reproducibility of science and access to information. However, these initiatives do not promote access to scientific equipment necessary for experiments. Mostly due to monetary constraints, equipment availability has always been uneven around the globe, affecting predominantly low-income countries and institutions. Here, a case is made for the use of free open source hardware in research and education, including countries and institutions where funds were never the biggest problem.


PLoS Biol


PLoS biology


Maia Chagas A




Has Abstract


2018-09-27 00:00:00














  • Group IV phospholipase A(2)alpha controls the formation of inter-cisternal continuities involved in intra-Golgi transport.

    abstract::The organization of intra-Golgi trafficking and the nature of the transport intermediates involved (e.g., vesicles, tubules, or tubular continuities) remain incompletely understood. It was recently shown that successive cisternae in the Golgi stack are interconnected by membrane tubules that form during the arrival of...

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    authors: San Pietro E,Capestrano M,Polishchuk EV,DiPentima A,Trucco A,Zizza P,Mariggiò S,Pulvirenti T,Sallese M,Tete S,Mironov AA,Leslie CC,Corda D,Luini A,Polishchuk RS

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    journal_title:PLoS biology

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    authors: Hussain A,Zhang M,Üçpunar HK,Svensson T,Quillery E,Gompel N,Ignell R,Grunwald Kadow IC

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  • Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1.

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    journal_title:PLoS biology

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  • Cyclin-dependent Kinase 1 and Aurora Kinase choreograph mitotic storage and redistribution of a growth factor receptor.

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    journal_title:PLoS biology

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    authors: Cota CD,Dreier MS,Colgan W,Cha A,Sia T,Davidson B

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    journal_title:PLoS biology

    pub_type: 评论,杂志文章


    authors: McAfee A,Pettis JS,Tarpy DR,Foster LJ

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    journal_title:PLoS biology

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    journal_title:PLoS biology

    pub_type: 杂志文章


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  • A c-di-GMP effector system controls cell adhesion by inside-out signaling and surface protein cleavage.

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    journal_title:PLoS biology

    pub_type: 杂志文章


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  • Understanding the evolutionary fate of finite populations: the dynamics of mutational effects.

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  • Correction: Novel Role of NOX in Supporting Aerobic Glycolysis in Cancer Cells with Mitochondrial Dysfunction and as a Potential Target for Cancer Therapy.

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    journal_title:PLoS biology

    pub_type: 杂志文章


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    journal_title:PLoS biology

    pub_type: 杂志文章


    authors: Ramos Pittol JM,Oruba A,Mittler G,Saccani S,van Essen D

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  • Effects of resveratrol and SIRT1 on PGC-1α activity and mitochondrial biogenesis: a reevaluation.

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    journal_title:PLoS biology

    pub_type: 杂志文章


    authors: Higashida K,Kim SH,Jung SR,Asaka M,Holloszy JO,Han DH

    更新日期:2013-07-01 00:00:00

  • The evolution of mutualism in gut microbiota via host epithelial selection.

    abstract::The human gut harbours a large and genetically diverse population of symbiotic microbes that both feed and protect the host. Evolutionary theory, however, predicts that such genetic diversity can destabilise mutualistic partnerships. How then can the mutualism of the human microbiota be explained? Here we develop an i...

    journal_title:PLoS biology

    pub_type: 杂志文章


    authors: Schluter J,Foster KR

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  • Regulation of mammary stem/progenitor cells by PTEN/Akt/beta-catenin signaling.

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    journal_title:PLoS biology

    pub_type: 杂志文章


    authors: Korkaya H,Paulson A,Charafe-Jauffret E,Ginestier C,Brown M,Dutcher J,Clouthier SG,Wicha MS

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  • A dual-specific macrophage colony-stimulating factor antagonist of c-FMS and αvβ3 integrin for osteoporosis therapy.

    abstract::There is currently a demand for new highly efficient and specific drugs to treat osteoporosis, a chronic bone disease affecting millions of people worldwide. We have developed a combinatorial strategy for engineering bispecific inhibitors that simultaneously target the unique combination of c-FMS and αvβ3 integrin, wh...

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    pub_type: 杂志文章


    authors: Zur Y,Rosenfeld L,Keshelman CA,Dalal N,Guterman-Ram G,Orenbuch A,Einav Y,Levaot N,Papo N

    更新日期:2018-08-24 00:00:00

  • Revisiting the basic reproductive number for malaria and its implications for malaria control.

    abstract::The prospects for the success of malaria control depend, in part, on the basic reproductive number for malaria, R0. Here, we estimate R0 in a novel way for 121 African populations, and thereby increase the number of R0 estimates for malaria by an order of magnitude. The estimates range from around one to more than 3,0...

    journal_title:PLoS biology

    pub_type: 杂志文章


    authors: Smith DL,McKenzie FE,Snow RW,Hay SI

    更新日期:2007-03-01 00:00:00

  • Self-organizing spots get under your skin.

    abstract::Sixty-five years after Turing first revealed the potential of systems with local activation and long-range inhibition to generate pattern, we have only recently begun to identify the biological elements that operate at many scales to generate periodic patterns in nature. In this Primer, we first review the theoretical...

    journal_title:PLoS biology

    pub_type: 杂志文章,评审


    authors: Dalle Nogare D,Chitnis AB

    更新日期:2017-12-20 00:00:00

  • Correction: Ionotropic Chemosensory Receptors Mediate the Taste and Smell of Polyamines.

    abstract::[This corrects the article DOI: 10.1371/journal.pbio.1002454.]. ...

    journal_title:PLoS biology

    pub_type: 杂志文章,已发布勘误


    authors: Hussain A,Zhang M,Üçpunar HK,Svensson T,Quillery E,Gompel N,Ignell R,Grunwald Kadow IC

    更新日期:2018-03-14 00:00:00

  • Phase-coding memories in mind.

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    journal_title:PLoS biology

    pub_type: 评论,杂志文章


    authors: Hakim N,Vogel EK

    更新日期:2018-08-29 00:00:00

  • Flight speeds among bird species: allometric and phylogenetic effects.

    abstract::Flight speed is expected to increase with mass and wing loading among flying animals and aircraft for fundamental aerodynamic reasons. Assuming geometrical and dynamical similarity, cruising flight speed is predicted to vary as (body mass)(1/6) and (wing loading)(1/2) among bird species. To test these scaling rules an...

    journal_title:PLoS biology

    pub_type: 杂志文章


    authors: Alerstam T,Rosén M,Bäckman J,Ericson PG,Hellgren O

    更新日期:2007-08-01 00:00:00

  • Selection for social signalling drives the evolution of chameleon colour change.

    abstract::Rapid colour change is a remarkable natural phenomenon that has evolved in several vertebrate and invertebrate lineages. The two principal explanations for the evolution of this adaptive strategy are (1) natural selection for crypsis (camouflage) against a range of different backgrounds and (2) selection for conspicuo...

    journal_title:PLoS biology

    pub_type: 杂志文章


    authors: Stuart-Fox D,Moussalli A

    更新日期:2008-01-01 00:00:00

  • An Estimate of the Total DNA in the Biosphere.

    abstract::Modern whole-organism genome analysis, in combination with biomass estimates, allows us to estimate a lower bound on the total information content in the biosphere: 5.3 × 1031 (±3.6 × 1031) megabases (Mb) of DNA. Given conservative estimates regarding DNA transcription rates, this information content suggests biospher...

    journal_title:PLoS biology

    pub_type: 杂志文章


    authors: Landenmark HK,Forgan DH,Cockell CS

    更新日期:2015-06-11 00:00:00

  • Correction: Song playbacks demonstrate slower evolution of song discrimination in birds from Amazonia than from temperate North America.

    abstract::[This corrects the article DOI: 10.1371/journal.pbio.3000478.]. ...

    journal_title:PLoS biology

    pub_type: 已发布勘误


    authors: PLOS Biology Staff.

    更新日期:2019-11-13 00:00:00

  • From dinosaurs to modern bird diversity: extending the time scale of adaptive radiation.

    abstract::What explains why some groups of organisms, like birds, are so species rich? And what explains their extraordinary ecological diversity, ranging from large, flightless birds to small migratory species that fly thousand of kilometers every year? These and similar questions have spurred great interest in adaptive radiat...

    journal_title:PLoS biology

    pub_type: 杂志文章


    authors: Moen D,Morlon H

    更新日期:2014-05-06 00:00:00