Status (on/off) of oipA gene: their associations with gastritis and gastric cancer and geographic origins.


:Virulence factors of H. pylori, such as outer inflammatory protein A (oipA), are closely involved in the development of gastric diseases such as chronic gastritis and gastric cancer. The functional status of oipA is regulated by a repair mechanism based on CT dinucleotide repeats that influence the reading frame, thus granting the gene a functional or nonfunctional status; in other words, the functional status of the oipA gene seems to be associated with the development of gastric diseases. This study sought to detect the presence of the oipA gene and to determine its functional status in patients with gastric diseases. We analyzed 516 biopsy samples (101 with normal gastric tissue, 365 with chronic gastritis, and 50 with gastric cancer). The presence of oipA was determined by PCR, and the gene status was determined using sequencing reactions. The oipA gene was found to be associated with the development of chronic gastritis, and the "on" status of the gene was the most frequent in patients with gastric cancer who were from Western countries. The CT repeats revealed geographic characteristics, but it is the functional status of the oipA gene that seems to be involved in the development of gastric diseases and in the development of gastric cancer in particular.


Arch Microbiol


Archives of microbiology


Sallas ML,Dos Santos MP,Orcini WA,David ÉB,Peruquetti RL,Payão SLM,Rasmussen LT




Has Abstract


2019-01-01 00:00:00














  • Close genetic relationship between Nitrobacter hamburgensis nitrite oxidoreductase and Escherichia coli nitrate reductases.

    abstract::The nitrite oxidoreductase (NOR) from the facultative nitrite-oxidizing bacterium Nitrobacter hamburgensis X14 was investigated genetically. In order to develop a probe for the gene norB, the N-terminal amino acid sequence of the NOR beta-subunit (NorB) was determined. Based on that amino acid sequence, an oligonucleo...

    journal_title:Archives of microbiology

    pub_type: 杂志文章


    authors: Kirstein K,Bock E

    更新日期:1993-01-01 00:00:00

  • Periplasmic superoxide dismutases in Aquaspirillum magnetotacticum.

    abstract::Aquaspirillum magnetotacticum MS-1 cells cultured microaerobically (dissolved O2 tension 1% of saturation), expressed proteins with superoxide dismutase (SOD) activity. The majority (roughly 95%) of total cell superoxide dismutase activity was located in the cell periplasm with little or no activity in the cell cytopl...

    journal_title:Archives of microbiology

    pub_type: 杂志文章


    authors: Short KA,Blakemore RP

    更新日期:1989-01-01 00:00:00

  • Changes in phosphatase activity associated with cell wall defects in Chlamydomonas reinhardi.

    abstract::Experiments were performed to isolate mutants lacking alkaline phosphatase in Chlamydomonas reinhardi. Mutants with null enzyme activity were obtained. A cytological study of these mutants however revealed cell wall defects, suggesting that the loss of phosphatase activity in these strains is not due to the inactivati...

    journal_title:Archives of microbiology

    pub_type: 杂志文章


    authors: Loppes R,Deltour R

    更新日期:1975-05-05 00:00:00

  • Bacillus amyloliquefaciens strains isolated from moisture-damaged buildings produced surfactin and a substance toxic to mammalian cells.

    abstract::Fungicidic Bacillus amyloliquefaciens strains isolated from the indoor environment of moisture-damaged buildings contained heat-stable, methanol-soluble substances that inhibited motility of boar spermatozoa within 15 min of exposure and killed feline lung cells in high dilution in 1 day. Boar sperm cells lost motilit...

    journal_title:Archives of microbiology

    pub_type: 杂志文章


    authors: Mikkola R,Andersson MA,Grigoriev P,Teplova VV,Saris NE,Rainey FA,Salkinoja-Salonen MS

    更新日期:2004-04-01 00:00:00

  • A comparative study of the evolution of cellobiose utilization in Escherichia coli and Shigella sonnei.

    abstract::The chb operon of Escherichia coli is involved in the utilization of chitooligosaccharides. While acquisition of two classes of mutations leading to altered regulation of the chb operon is necessary to confer the ability to utilize the glucose disaccharide cellobiose to wild-type strains of E. coli, in the closely rel...

    journal_title:Archives of microbiology

    pub_type: 杂志文章


    authors: Joseph AM,Sonowal R,Mahadevan S

    更新日期:2017-03-01 00:00:00

  • Alpha-ketoglutarate enhances freeze-thaw tolerance and prevents carbohydrate-induced cell death of the yeast Saccharomyces cerevisiae.

    abstract::Stress resistance and fermentative capability are important quality characteristics of baker's yeast. In the present study, we examined protective effects of exogenous alpha-ketoglutarate (AKG), an intermediate of the tricarboxylic acid cycle and amino acid metabolism, against freeze-thaw and carbohydrate-induced stre...

    journal_title:Archives of microbiology

    pub_type: 杂志文章


    authors: Bayliak MM,Hrynkiv OV,Knyhynytska RV,Lushchak VI

    更新日期:2018-01-01 00:00:00

  • An ammonia-oxidizing bacterium, Nitrosovibrio tenuis nov. gen. nov. sp.

    abstract::An ammonia-oxidizing, autotroph growing, slender, curved rod was isolated from the soil of Hawaii. It is well distinguishable from any other nitrifying bacteria thus far described by their morphology. The cells are 1.1-3.0 mum long and 0.3-0.4 mum wide. They are motile by means of 1-4 subpolar to lateral flagella. In ...

    journal_title:Archives of microbiology

    pub_type: 杂志文章


    authors: Harms H,Koops HP,Wehrmann H

    更新日期:1976-05-03 00:00:00

  • Terraforming: synthetic biology's final frontier.

    abstract::Synthetic biology, the design and synthesis of synthetic biological systems from DNA to whole cells, has provided us with the ultimate tools for space exploration and colonisation. Herein, we explore some of the most significant advances and future prospects in the field of synthetic biology, in the context of astrobi...

    journal_title:Archives of microbiology

    pub_type: 信件


    authors: Sleator RD,Smith N

    更新日期:2019-08-01 00:00:00

  • A serine alkaline protease from the fungus Conidiobolus coronatus with a distinctly different structure than the serine protease subtilisin Carlsberg.

    abstract::In view of the functional similarities between subtilisin Carlsberg and the alkaline protease from Conidiobolus coronatus, the biochemical and structural properties of the two enzymes were compared. In spite of their similar biochemical properties, e.g., pH optima, heat stability, molecular mass, pI, esterase activity...

    journal_title:Archives of microbiology

    pub_type: 杂志文章


    authors: Phadtare S,Rao M,Deshpande V

    更新日期:1996-12-01 00:00:00

  • Morphological and molecular characterization of Frankia sp. isolates from nodules of Alnus nepalensis Don.

    abstract::Nodules collected from Alnus nepalensis growing in mixed forest stands at three different sites around Shillong, were crushed in various culture media to obtain isolates of Frankia. The isolates were found to have typical Frankia morphology as revealed by the scanning electron microscope. Seedlings inoculated with iso...

    journal_title:Archives of microbiology

    pub_type: 杂志文章


    authors: Ganesh G,Misra AK,Chapelon C,Normand P

    更新日期:1994-01-01 00:00:00

  • Could DNA uptake be a side effect of bacterial adhesion and twitching motility?

    abstract::DNA acquisition promotes the spread of resistance to antibiotics and virulence among bacteria. It is also linked to several natural phenomena including recombination, genome dynamics, adaptation and speciation. Horizontal DNA transfer between bacteria occurs via conjugation, transduction or competence for natural tran...

    journal_title:Archives of microbiology

    pub_type: 杂志文章,评审


    authors: Bakkali M

    更新日期:2013-04-01 00:00:00

  • Osmoregulation in Escherichia coli by accumulation of organic osmolytes: betaines, glutamic acid, and trehalose.

    abstract::It has been shown previously that externally added glycine betaine is accumulated in Escherichia coli in response to the external osmotic strength. Here we have shown, by using nuclear magnetic resonance spectroscopy and radiochemical methods, that E. coli growing in a glucose-mineral medium of elevated osmotic streng...

    journal_title:Archives of microbiology

    pub_type: 杂志文章


    authors: Larsen PI,Sydnes LK,Landfald B,Strøm AR

    更新日期:1987-02-01 00:00:00

  • Characterization of a carbofuran-degrading bacterium and investigation of the role of plasmids in catabolism of the insecticide carbofuran.

    abstract::A bacterium capable of using the carbamate insecticide carbofuran as a sole source of carbon and energy, was isolated from soil. The ability to catabolise carbofuran phenol, produced by cleavage of the carbamate ester linkage of the insecticide, was lost at very high frequency when the bacterium was grown in the absen...

    journal_title:Archives of microbiology

    pub_type: 杂志文章


    authors: Head IM,Cain RB,Suett DL

    更新日期:1992-01-01 00:00:00

  • Tubular structures of Vibrio psychroerythrus.

    abstract::The marine bacterium Vibrio psychoerythrus, an obligate psychrophile, contains uniformly dense rod-shaped organelles 10-15 nm wide and up to 1.3 mum long. These structures were frequently seen crossing the septum of dividing cells. ...

    journal_title:Archives of microbiology

    pub_type: 杂志文章


    authors: D'Aoust JY,Kushner DJ

    更新日期:1976-02-01 00:00:00

  • Spectroscopic properties and related functions of the stigma measured in living cells of Euglena gracilis.

    abstract::The spectroscopic properties of stigma inside green and dark-grown cells and of isolated stigma globules have been studied by means of a microspectrophotometer build in the Laboratory. On the base of these results and of the analysis of the absorption spectra of a stigma suspension, cell suspension and the cell methan...

    journal_title:Archives of microbiology

    pub_type: 杂志文章


    authors: Benedetti PA,Bianchini G,Checcucci A,Ferrara R,Grassi S

    更新日期:1976-12-01 00:00:00

  • Growth kinetics of a Vero cells adapted Bangladeshi strain of peste des petits ruminants (PPR) virus in cell culture.

    abstract::Growth kinetics of a Vero cells adapted Bangladeshi strain of peste des petits ruminants virus was studied in Vero cells to determine maximum virus yield. One-step growth curve was formulated after determining virus in both supernatant (CFV) and cell lysate (CAV) at different time categories by microtitre plate titrat...

    journal_title:Archives of microbiology

    pub_type: 杂志文章


    authors: Siddiqui MSI,Islam MR,Chowdhury EH

    更新日期:2021-01-05 00:00:00

  • Ethanol-sensitive mutants of Saccharomyces cerevisiae.

    abstract::Saccharomyces cerevisiae mutants unable to grow at ethanol concentrations at which the wild type strain S288C does grow, have been isolated. Some of them show additional phenotypic alterations in colony size, temperature sensitivity and viability in ethanol, which cosegregate with the growth sensitivity in ethanol. 21...

    journal_title:Archives of microbiology

    pub_type: 杂志文章


    authors: Aguilera A,Benítez T

    更新日期:1986-01-01 00:00:00

  • Aldolases of the lactic acid bacteria. Demonstration of immunological relationships among eight genera of Gram positive bacteria using an anti-pediococcal aldolase serum.

    abstract::Reciprocal qualitative and quantitative immunological experiments employing an anti-Pediococcus cerevisiae aldolase serum confirmed many of the interspecific relationships demonstrated previously among lactic acid bacteria with antisera prepared against the Streptococcus faecalis fructose diphosphate aldolase. The ext...

    journal_title:Archives of microbiology

    pub_type: 杂志文章


    authors: London J,Chace NM

    更新日期:1976-10-11 00:00:00

  • Induction of beta-oxidation enzymes and microbody proliferation in Aspergillus nidulans.

    abstract::Aspergillus nidulans is able to grow on oleic acid as sole carbon source. Characterization of the oleate-induced beta-oxidation pathway showed the presence of the two enzyme activities involved in the first step of this catabolic system: acyl-CoA oxidase and acyl-CoA dehydrogenase. After isopicnic centrifugation in a ...

    journal_title:Archives of microbiology

    pub_type: 杂志文章


    authors: Valenciano S,Lucas JR,Pedregosa A,Monistrol IF,Laborda F

    更新日期:1996-11-01 00:00:00

  • Genetic and biochemical analyses of chlorobenzene degradation gene clusters in Pandoraea sp. strain MCB032.

    abstract::Pandoraea sp. strain MCB032 was isolated as an emerging chlorobenzene degrader from a functionally stable bioreactor where species succession had occurred. In this study, two gene clusters encoding chlorobenzene metabolic functions have been cloned. Within the cbs gene cluster, CbsA and CbsB are similar to the chlorob...

    journal_title:Archives of microbiology

    pub_type: 杂志文章


    authors: Jiang XW,Liu H,Xu Y,Wang SJ,Leak DJ,Zhou NY

    更新日期:2009-06-01 00:00:00

  • Isolation and characterization of a unique protease from sporulating cells of Bacillus subtilis.

    abstract::Two proteases, designated I and II, have been isolated from sporulating cells of Bacillus subtilis. They were partially purified by ammonium sulfate fractionation, Sephadex chromatography and affinity columns. Protease I was found to be similar to an already characterized B. subtilis protease. Protease II is trypsin-l...

    journal_title:Archives of microbiology

    pub_type: 杂志文章


    authors: Srivastava OP,Aronson AI

    更新日期:1981-05-01 00:00:00

  • Hydrolysis of fungal and plant cell walls by enzymatic complexes from cultures of Fusarium isolates with different aggressiveness to rye (Secale cereale).

    abstract::The efficiency of hydrolysis of fungal (Fusarium spp.) cell wall and rye root cell wall by crude enzymatic complexes from (42-day-old) cultures of three F. culmorum isolates, a plant growth-promoting rhizosphere isolate (PGPF) DEMFc2, a deleterious rhizosphere isolate (DRMO) DEMFc5, and a pathogenic isolate DEMFc37, a...

    journal_title:Archives of microbiology

    pub_type: 杂志文章


    authors: Jaroszuk-Ściseł J,Kurek E

    更新日期:2012-08-01 00:00:00

  • [Utilization of trimethylammonium-compounds by Acinetobacter calcoaceticus (author's transl)].

    abstract::The utilization of carnitine and carnitine derivatives (O-acylcarnitines, carnitine carboxylderivatives) and structure-related trimethylammonium-compounds (betaines and nitrogen-bases) by Acinetobacter calcoaceticus was studied by means of the control of growth and the quantitative detection of metabolites. The strain...

    journal_title:Archives of microbiology

    pub_type: 杂志文章


    authors: Kleber H-P,Seim H,Aurich H,Strack E

    更新日期:1977-03-01 00:00:00

  • Genome-wide transcriptional responses of Nitrosomonas europaea to zinc.

    abstract::Nitrosomonas europaea, a Gram-negative obligate chemolithoautotroph, participates in global nitrogen cycling by carrying out nitrification and derives energy for growth through oxidation of ammonia. In this work, the physiological, proteomic, and transcriptional responses of N. europaea to zinc stress were studied. Th...

    journal_title:Archives of microbiology

    pub_type: 杂志文章


    authors: Park S,Ely RL

    更新日期:2008-06-01 00:00:00

  • Evaluation of mtr cluster expression in Shewanella RCRI7 during uranium removal.

    abstract::In recent years, bioremediation is considered as an efficient method to remove the pollutants from the industrial wastewater. In this study, quantitative gene expressions (Real-time RT-PCR) of mtr gene cluster (mtrA, mtrB, mtrC, mtrD, mtrE, mtrF and omcA) in five different uranium concentrations (0.1, 0.25, 0.5, 1 and...

    journal_title:Archives of microbiology

    pub_type: 杂志文章


    authors: Ghasemi R,Fatemi F,Mir-Derikvand M,Zarei M

    更新日期:2020-12-01 00:00:00

  • Quinolinate dehydrogenase and 6-hydroxyquinolinate decarboxylase involved in the conversion of quinolinic acid to 6-hydroxypicolinic acid by Alcaligenes sp. strain UK21.

    abstract::In the conversion of quinolinic acid to 6-hydroxypicolinic acid by whole cells of Alcaligenes sp. strain UK21, the enzyme reactions involved in the hydroxylation and decarboxylation of quinolinic acid were examined. Quinolinate dehydrogenase, which catalyzes the first step, the hydroxylation of quinolinic acid, was so...

    journal_title:Archives of microbiology

    pub_type: 杂志文章


    authors: Uchida A,Ogawa M,Yoshida T,Nagasawa T

    更新日期:2003-08-01 00:00:00

  • Factors affecting transcriptional regulation of the formate-hydrogen-lyase pathway of Escherichia coli.

    abstract::The regulatory elements involved in expression of the gene (fdhF) for the selenopolypeptide of formate dehydrogenase and of a gene (or transcriptional unit) (hyd) specifically responsible for the formation of the gas-evolving hydrogenase (hydrogenase 3) in Escherichia coli were investigated. Formate (or a product of i...

    journal_title:Archives of microbiology

    pub_type: 杂志文章


    authors: Birkmann A,Zinoni F,Sawers G,Böck A

    更新日期:1987-06-01 00:00:00

  • Microbial N-cycling gene abundance is affected by cover crop specie and development stage in an integrated cropping system.

    abstract::Grasses of the Urochloa genus have been widely used in crop-livestock integration systems or as cover crops in no-till systems such as in rotation with maize. Some species of Urochloa have mechanisms to reduce nitrification. However, the responses of microbial functions in crop-rotation systems with grasses and its co...

    journal_title:Archives of microbiology

    pub_type: 杂志文章


    authors: Rocha KF,Kuramae EE,Borges BMF,Leite MFA,Rosolem CA

    更新日期:2020-09-01 00:00:00

  • Role of respiration and glutathione in cadmium-induced oxidative stress in Escherichia coli K-12.

    abstract::Cadmium is a widespread pollutant that has been associated with oxidative stress, but the mechanism behind this effect in prokaryotes is still unclear. In this work, we exposed two glutathione deficient mutants (DeltagshA and DeltagshB) and one respiration deficient mutant (DeltaubiE) to a sublethal concentration of c...

    journal_title:Archives of microbiology

    pub_type: 杂志文章


    authors: Pacheco CC,Passos JF,Castro AR,Moradas-Ferreira P,De Marco P

    更新日期:2008-03-01 00:00:00

  • Characterization of Bacillus subtilis YfkE (ChaA): a calcium-specific Ca2+/H+ antiporter of the CaCA family.

    abstract::YfkE, a protein from Bacillus subtilis, exhibits homology to the Ca(2+):Cation Antiporter (CaCA) Family. In a fluorescence-based assay of everted membrane vesicles prepared from Na(+)(Ca(2+))/H(+) antiporter-defective mutant Escherichia coli KNabc, YfkE exhibited robust Ca(2+)/H(+) antiport activity, with a K (m) for ...

    journal_title:Archives of microbiology

    pub_type: 杂志文章


    authors: Fujisawa M,Wada Y,Tsuchiya T,Ito M

    更新日期:2009-08-01 00:00:00