Skin color-specific and spectrally-selective naked-eye dosimetry of UVA, B and C radiations.

abstract：:The gating mechanism of transmembrane ion channels is crucial for understanding how these proteins control ion flow across membranes in various physiological processes. Big potassium (BK) channels are particularly interesting with large single-channel conductance and dual regulation by membrane voltage and intracellul...

journal_title：Nature communications

authors： Jia Z,Yazdani M,Zhang G,Cui J,Chen J

更新日期：2018-08-24 00:00:00

abstract：:Clustered regularly-interspaced palindromic repeats (CRISPR)-based genetic screens using single-guide-RNA (sgRNA) libraries have proven powerful to identify genetic regulators. Applying CRISPR screens to interrogate functional elements in noncoding regions requires generating sgRNA libraries that are densely covering,...

journal_title：Nature communications

authors： Cheng J,Roden CA,Pan W,Zhu S,Baccei A,Pan X,Jiang T,Kluger Y,Weissman SM,Guo S,Flavell RA,Ding Y,Lu J

更新日期：2016-03-30 00:00:00

abstract：:Inferring neural mechanisms from functional magnetic resonance imaging (fMRI) is challenging because the fMRI signal integrates over millions of neurons. One approach is to compare computational models that map neural activity to fMRI responses, to see which best predicts fMRI data. We use this approach to compare fou...

journal_title：Nature communications

authors： Alink A,Abdulrahman H,Henson RN

更新日期：2018-09-21 00:00:00

abstract：:Two-Photon Microscopy has become an invaluable tool for biological and medical research, providing high sensitivity, molecular specificity, inherent three-dimensional sub-cellular resolution and deep tissue penetration. In terms of imaging speeds, however, mechanical scanners still limit the acquisition rates to typic...

journal_title：Nature communications

authors： Karpf S,Riche CT,Di Carlo D,Goel A,Zeiger WA,Suresh A,Portera-Cailliau C,Jalali B

更新日期：2020-04-28 00:00:00

abstract：:Rearrangement reactions have attracted considerable interest over the past decades due to their high bond-forming efficiency and atom economy in the construction of complex organic architectures. In contrast to the well-established [3,3]-rearrangement, [1,3] O-to-C rearrangement has been far less vigorously investigat...

journal_title：Nature communications

authors： Zhou B,Zhang YQ,Zhang K,Yang MY,Chen YB,Li Y,Peng Q,Zhu SF,Zhou QL,Ye LW

更新日期：2019-07-19 00:00:00

abstract：:Time-resolved photoelectron spectroscopy (TRPES) is a useful approach to elucidate the coupled electronic-nuclear quantum dynamics underlying chemical processes, but has remained limited by the use of low photon energies. Here, we demonstrate the general advantages of XUV-TRPES through an application to NO2, one of th...

journal_title：Nature communications

authors： von Conta A,Tehlar A,Schletter A,Arasaki Y,Takatsuka K,Wörner HJ

更新日期：2018-08-08 00:00:00

abstract：:Laboratory spectroscopy of atomic hydrogen in a magnetic flux density of 10(5) T (1 gigagauss), the maximum observed on high-field magnetic white dwarfs, is impossible because practically available fields are about a thousand times less. In this regime, the cyclotron and binding energies become equal. Here we demonstr...

journal_title：Nature communications

authors： Murdin BN,Li J,Pang ML,Bowyer ET,Litvinenko KL,Clowes SK,Engelkamp H,Pidgeon CR,Galbraith I,Abrosimov NV,Riemann H,Pavlov SG,Hübers HW,Murdin PG

更新日期：2013-01-01 00:00:00

abstract：:In addition to acting as a cellular energy source, ATP can also act as a damage-associated molecular pattern in both animals and plants. Stomata are leaf pores that control gas exchange and, therefore, impact critical functions such as photosynthesis, drought tolerance, and also are the preferred entry point for patho...

journal_title：Nature communications

authors： Chen D,Cao Y,Li H,Kim D,Ahsan N,Thelen J,Stacey G

更新日期：2017-12-22 00:00:00

abstract：:Zero-energy particles (such as Majorana fermions) are newly predicted quasiparticles and are expected to play an important role in fault-tolerant quantum computation. In conventional Hermitian quantum systems, however, such zero states are vulnerable and even become vanishing if couplings with surroundings are of the ...

journal_title：Nature communications

authors： Pan M,Zhao H,Miao P,Longhi S,Feng L

更新日期：2018-04-03 00:00:00

abstract：:Although B cell response is frequently found in cancer, there is little evidence that it alters tumor development or progression. The process through which tumor-associated antigens trigger humoral response is not well delineated. We investigate the repertoire of antigens associated with humoral immune response in pan...

journal_title：Nature communications

authors： Capello M,Vykoukal JV,Katayama H,Bantis LE,Wang H,Kundnani DL,Aguilar-Bonavides C,Aguilar M,Tripathi SC,Dhillon DS,Momin AA,Peters H,Katz MH,Alvarez H,Bernard V,Ferri-Borgogno S,Brand R,Adler DG,Firpo MA,Mulvihill S

更新日期：2019-01-16 00:00:00

abstract：:Magnetic resonance spectroscopy is one of the most important tools in chemical and bio-medical research. However, sensitivity limitations typically restrict imaging resolution to ~ 10 µm. Here we bring quantum control to the detection of chemical systems to demonstrate high-resolution electron spin imaging using the q...

journal_title：Nature communications

authors： Simpson DA,Ryan RG,Hall LT,Panchenko E,Drew SC,Petrou S,Donnelly PS,Mulvaney P,Hollenberg LCL

更新日期：2017-09-06 00:00:00

abstract：:Intense ultrashort X-ray pulses produced by modern free-electron lasers (FELs) allow one to probe biological systems, inorganic materials and molecular reaction dynamics with nanoscale spatial and femtoscale temporal resolution. These experiments require the knowledge, and possibly the control, of the spectro-temporal...

journal_title：Nature communications

authors： De Ninno G,Gauthier D,Mahieu B,Ribič PR,Allaria E,Cinquegrana P,Danailov MB,Demidovich A,Ferrari E,Giannessi L,Penco G,Sigalotti P,Stupar M

更新日期：2015-08-20 00:00:00

abstract：:Autophosphorylation of amino-acid residues is part of the folding process of various protein kinases. Conventional chemical screening of mature kinases has missed inhibitors that selectively interfere with the folding process. Here we report a cell-based assay that evaluates inhibition of a kinase at a transitional st...

journal_title：Nature communications

authors： Kii I,Sumida Y,Goto T,Sonamoto R,Okuno Y,Yoshida S,Kato-Sumida T,Koike Y,Abe M,Nonaka Y,Ikura T,Ito N,Shibuya H,Hosoya T,Hagiwara M

更新日期：2016-04-22 00:00:00

abstract：:In LaAlO(3)/SrTiO(3) heterointerfaces, charge carriers migrate from the LaAlO(3) to the interface in an electronic reconstruction. Magnetism has been observed in LaAlO(3)/SrTiO(3), but its relationship to the interface conductivity is unknown. Here we show that reconstruction is necessary, but not sufficient, for the ...

journal_title：Nature communications

authors： Kalisky B,Bert JA,Klopfer BB,Bell C,Sato HK,Hosoda M,Hikita Y,Hwang HY,Moler KA

更新日期：2012-06-26 00:00:00

abstract：:Visualizing the rearrangement of atoms in a wide range of molecular and condensed-matter systems requires resolving picometre displacements on a 10-fs timescale, which is achievable using pump-probe diffraction, given short enough pulses. Here we demonstrate the compression of single-electron pulses with a de Broglie ...

journal_title：Nature communications

authors： Gliserin A,Walbran M,Krausz F,Baum P

更新日期：2015-10-27 00:00:00

abstract：:Predictable stereoselective formation of supramolecular assembly is generally believed to be an important but complicated process. Here, we show that point chirality of a ligand decisively influences its supramolecular assembly behavior. We designed three closely related chiral ligands with different point chiralities...

journal_title：Nature communications

authors： Yeung CT,Yim KH,Wong HY,Pal R,Lo WS,Yan SC,Yee-Man Wong M,Yufit D,Smiles DE,McCormick LJ,Teat SJ,Shuh DK,Wong WT,Law GL

更新日期：2017-10-24 00:00:00

abstract：:The midge, Belgica antarctica, is the only insect endemic to Antarctica, and thus it offers a powerful model for probing responses to extreme temperatures, freeze tolerance, dehydration, osmotic stress, ultraviolet radiation and other forms of environmental stress. Here we present the first genome assembly of an extre...

journal_title：Nature communications

authors： Kelley JL,Peyton JT,Fiston-Lavier AS,Teets NM,Yee MC,Johnston JS,Bustamante CD,Lee RE,Denlinger DL

更新日期：2014-08-12 00:00:00

abstract：:The cellular mechanisms driving cardiac tissue formation remain poorly understood, largely due to the structural and functional complexity of the heart. It is unclear whether newly generated myocytes originate from cardiac stem/progenitor cells or from pre-existing cardiomyocytes that re-enter the cell cycle. Here, we...

journal_title：Nature communications

authors： Sereti KI,Nguyen NB,Kamran P,Zhao P,Ranjbarvaziri S,Park S,Sabri S,Engel JL,Sung K,Kulkarni RP,Ding Y,Hsiai TK,Plath K,Ernst J,Sahoo D,Mikkola HKA,Iruela-Arispe ML,Ardehali R

更新日期：2018-02-21 00:00:00

abstract：:Nuclear factor-κB (NFκB) and peroxisome proliferator activated receptor-γ (PPARγ) are both transcription factors that perform distinct but overlapping roles in cellular regulation. Here we report that PPARγ acts as an E3 ubiquitin ligase, physically interacting with p65 to induce its ubiquitination and degradation. Th...

journal_title：Nature communications

authors： Hou Y,Moreau F,Chadee K

更新日期：2012-01-01 00:00:00

abstract：:India is located at a critical geographic crossroads for understanding the dispersal of Homo sapiens out of Africa and into Asia and Oceania. Here we report evidence for long-term human occupation, spanning the last ~80 thousand years, at the site of Dhaba in the Middle Son River Valley of Central India. An unchanging...

journal_title：Nature communications

authors： Clarkson C,Harris C,Li B,Neudorf CM,Roberts RG,Lane C,Norman K,Pal J,Jones S,Shipton C,Koshy J,Gupta MC,Mishra DP,Dubey AK,Boivin N,Petraglia M

更新日期：2020-02-25 00:00:00

abstract：:We constructed an intelligent cloud lab that integrates lab automation with cloud servers and artificial intelligence (AI) to detect chirality in perovskites. Driven by the materials acceleration operating system in cloud (MAOSIC) platform, on-demand experimental design by remote users was enabled in this cloud lab. B...

journal_title：Nature communications

authors： Li J,Li J,Liu R,Tu Y,Li Y,Cheng J,He T,Zhu X

更新日期：2020-04-27 00:00:00

abstract：:In conventional computers, wiring between transistors is required to enable the execution of Boolean logic functions. This has resulted in processors in which billions of transistors are physically interconnected, which limits integration densities, gives rise to huge power consumption and restricts processing speeds....

journal_title：Nature communications

authors： Mahboob I,Flurin E,Nishiguchi K,Fujiwara A,Yamaguchi H

更新日期：2011-02-15 00:00:00

abstract：:Selective thermal emission in a useful range of energies from a material operating at high temperatures is required for effective solar thermophotovoltaic energy conversion. Three-dimensional metallic photonic crystals can exhibit spectral emissivity that is modified compared with the emissivity of unstructured metals...

journal_title：Nature communications

authors： Arpin KA,Losego MD,Cloud AN,Ning H,Mallek J,Sergeant NP,Zhu L,Yu Z,Kalanyan B,Parsons GN,Girolami GS,Abelson JR,Fan S,Braun PV

更新日期：2013-01-01 00:00:00

abstract：:Understanding the dynamics of ring polymers is a particularly challenging yet interesting problem in soft materials. Despite recent progress, a complete understanding of the nonequilibrium behavior of ring polymers has not yet been achieved. In this work, we directly observe the flow dynamics of DNA-based rings in sem...

journal_title：Nature communications

authors： Zhou Y,Hsiao KW,Regan KE,Kong D,McKenna GB,Robertson-Anderson RM,Schroeder CM

更新日期：2019-04-15 00:00:00

abstract：:Gross chromosomal rearrangements (GCRs), such as translocations, deletions or inversions, are often generated by illegitimate repair between two DNA breakages at regions with nucleotide sequences that might potentially adopt a non-B DNA conformation. We previously established a plasmid-based model system that recapitu...

journal_title：Nature communications

authors： Inagaki H,Ohye T,Kogo H,Tsutsumi M,Kato T,Tong M,Emanuel BS,Kurahashi H

更新日期：2013-01-01 00:00:00

abstract：:Proton conduction is a fundamental process in biology and in devices such as proton exchange membrane fuel cells. To maximize proton conduction, three-dimensional conduction pathways are preferred over one-dimensional pathways, which prevent conduction in two dimensions. Many crystalline porous solids to date show one...

journal_title：Nature communications

authors： Liu M,Chen L,Lewis S,Chong SY,Little MA,Hasell T,Aldous IM,Brown CM,Smith MW,Morrison CA,Hardwick LJ,Cooper AI

更新日期：2016-09-13 00:00:00

abstract：:Warming in the Arctic accelerates thawing of permafrost-affected soils, which leads to a release of greenhouse gases to the atmosphere. We do not know whether permafrost thaw also releases non-methane volatile organic compounds that can contribute to both negative and positive radiative forcing on climate. Here we sho...

journal_title：Nature communications

authors： Kramshøj M,Albers CN,Holst T,Holzinger R,Elberling B,Rinnan R

更新日期：2018-08-24 00:00:00

abstract：:The Paris Agreement set a goal to keep global warming well below 2 °C and pursue efforts to limit it to 1.5 °C. Understanding how 0.5 °C less warming reduces impacts and risks is key for climate policies. Here, we show that both areal and population exposures to dangerous extreme precipitation events (e.g., once in 10...

journal_title：Nature communications

authors： Zhang W,Zhou T,Zou L,Zhang L,Chen X

更新日期：2018-08-08 00:00:00

abstract：:Bell correlations are a foundational demonstration of how quantum entanglement contradicts the classical notion of local realism. Rigorous validation of quantum nonlocality have only been achieved between solid-state electron spins, internal states of trapped atoms, and photon polarisations, all weakly coupling to gra...

journal_title：Nature communications

authors： Shin DK,Henson BM,Hodgman SS,Wasak T,Chwedeńczuk J,Truscott AG

更新日期：2019-10-01 00:00:00

abstract：:Tropical south-western Pacific temperatures are of vital importance to the Great Barrier Reef (GBR), but the role of sea surface temperatures (SSTs) in the growth of the GBR since the Last Glacial Maximum remains largely unknown. Here we present records of Sr/Ca and δ(18)O for Last Glacial Maximum and deglacial corals...

journal_title：Nature communications

authors： Felis T,McGregor HV,Linsley BK,Tudhope AW,Gagan MK,Suzuki A,Inoue M,Thomas AL,Esat TM,Thompson WG,Tiwari M,Potts DC,Mudelsee M,Yokoyama Y,Webster JM

更新日期：2014-06-17 00:00:00