Abstract：
:The multivariate nature of a fluidized bed system creates process complexity that increases the risk of production upset. This research explores the use of passive acoustic emissions monitoring paired with an artificial neural network to detect fluidized bed distributor plate blockage. In many cases, early process failure detection can allow for immediate intervention, thus lowering operation costs. Blockages were simulated by actively covering portions of a top-spray fluidized bed distributor plate. Piezoelectric microphones were placed within the fluidized bed exhaust and attached externally to the vessel wall. Several time and frequency domain feature vectors were extracted from the monitoring data using the open source pyAudioAnalysis library in Python. Through deep learning, the artificial neural network used these feature vectors to train against each distributor plate blockage condition. The deep learning model was then evaluated using k-fold cross validation. The findings were very positive and successfully demonstrated an application of deep learning to detect process upset.
journal_name
Int J Pharmjournal_title
International journal of pharmaceuticsauthors
Carter A,Briens Ldoi
10.1016/j.ijpharm.2018.08.052subject
Has Abstractpub_date
2018-12-01 00:00:00pages
235-240issue
1-2eissn
0378-5173issn
1873-3476pii
S0378-5173(18)30630-6journal_volume
552pub_type
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journal_title：International journal of pharmaceutics
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journal_title：International journal of pharmaceutics
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journal_title：International journal of pharmaceutics
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journal_title：International journal of pharmaceutics
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journal_title：International journal of pharmaceutics
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