A Temperature-Dependent Switch in Feeding Preference Improves Drosophila Development and Survival in the Cold.

Abstract:

:How cold-blooded animals acclimate to temperature and what determines the limits of their viable temperature range are not understood. Here, we show that Drosophila alter their dietary preference from yeast to plants when temperatures drop below 15°C and that the different lipids present in plants improve survival at low temperatures. We show that Drosophila require dietary unsaturated fatty acids present in plants to adjust membrane fluidity and maintain motor coordination. Feeding on plants extends lifespan and survival for many months at temperatures consistent with overwintering in temperate climates. Thus, physiological alterations caused by a temperature-dependent dietary shift could help Drosophila survive seasonal temperature changes.

journal_name

Dev Cell

journal_title

Developmental cell

authors

Brankatschk M,Gutmann T,Knittelfelder O,Palladini A,Prince E,Grzybek M,Brankatschk B,Shevchenko A,Coskun Ü,Eaton S

doi

10.1016/j.devcel.2018.05.028

subject

Has Abstract

pub_date

2018-09-24 00:00:00

pages

781-793.e4

issue

6

eissn

1534-5807

issn

1878-1551

pii

S1534-5807(18)30421-0

journal_volume

46

pub_type

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